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Invitrogen
alpha TTP Polyclonal Antibody
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Product Details
PA5-28781
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha TTP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546257
Product Specific Information
Recommended positive controls: IMR32, mouse liver, rat liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha TTP; Alpha-tocopherol transfer protein; Alpha-TTP; tocopherol (alpha) transfer protein; tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency); Tocopherol transfer protein alpha
Gene Aliases: alpha-TTP; alphaTTP; ATTP; AVED; TPP1; TTP; TTP1; TTPA
UniProt ID: (Human) P49638, (Rat) P41034, (Mouse) Q8BWP5
Entrez Gene ID: (Human) 7274, (Rat) 25571, (Chinese hamster) 100751868, (Mouse) 50500
placenta development
embryonic placenta development
response to nutrient
response to pH
response to toxic substance
developmental process
vitamin E metabolic process
intermembrane transport
vitamin transport
intracellular pH reduction
negative regulation of cell death
negative regulation of establishment of blood-brain barrier
transport
lipid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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