Proteintech

alpha Tubulin Monoclonal Antibody (1E4C11)

alpha Tubulin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 25

alpha Tubulin Antibody (66031-1-IG) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 66031-1-IG (alpha Tubulin antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IGG (H+L).

alpha Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

alpha Tubulin Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

alpha Tubulin Antibody in Western Blot (WB)

alpha Tubulin Antibody in Flow Cytometry (Flow)

alpha Tubulin Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

66031-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

View 643 publications 643 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:100

Immunocytochemistry (ICC/IF)

1:50-1:500

View 53 publications 53 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 8 publications 8 publications

Miscellaneous PubMed (MISC)

View 16 publications 16 publications

Not applicable (N/A)

View 29 publications 29 publications

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Published species

Human, Insect, Mouse, Non-human primate, Plant, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1E4C11

Immunogen

alpha Tubulin Fusion Protein Ag18034 (1-451 aa encoded by BC009314)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.73 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody specifically recognizes Tubulin Alpha.

Immunogen sequence: MRECISIHV GQAGVQIGNA CWELYCLEHG IQPDGQMPSD KTIGGGDDSF NTFFSETGAG KHVPRAVFVD LEPTVIDEVR TGTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIIDLVL DRIRKLADQC TGLQGFLVFH SFGGGTGSGF TSLLMERLSV DYGKKSKLEF SIYPAPQVST AVVEPYNSIL TTHTTLEHSD CAFMVDNEAI YDICRRNLDI ERPTYTNLNR LISQIVSSIT ASLRFDGALN VDLTEFQTNL VPYPRIHFPL ATYAPVISAE KAYHEQLSVA EITNACFEPA NQMVKCDPRH GKYMACCLLY RGDVVPKDVN AAIATIKTKR SIQFVDWCPT GFKVGINYQP PTVVPGGDLA KVQRAVCMLS NTTAIAEAWA RLDHKFDLMY AKRAFVHWYV GEGMEEGEFS EAREDMAALE KDYEEVGVDS VEGEGEEEGE EY (1-451 aa encoded by BC009314)

Target Information

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression.

Cell & bioscience

Chen L,Dong W,Zhou M,Yang C,Xiong M,Kazobinka G,Chen Z,Xing Y,Hou T

Mon Mar 06 00:00:00 UTC 2023

The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.

The Journal of cell biology

Gok MO,Connor OM,Wang X,Menezes CJ,Llamas CB,Mishra P,Friedman JR

Mon Apr 03 00:00:00 UTC 2023

Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.

Acta pharmacologica Sinica

Yang DG,Gao YY,Yin ZQ,Wang XR,Meng XS,Zou TF,Duan YJ,Chen YL,Liao CZ,Xie ZL,Fan XD,Sun L,Han JH,Yang XX

Wed Feb 01 00:00:00 UTC 2023

SLC27A4-mediated selective uptake of mono-unsaturated fatty acids promotes ferroptosis defense in hepatocellular carcinoma.

Free radical biology & medicine

Li Z,Liao X,Hu Y,Li M,Tang M,Zhang S,Mo S,Li X,Chen S,Qian W,Feng R,Yu R,Xu Y,Yuan S,Xie C,Li J

Sat May 20 00:00:00 UTC 2023

Repositioning linifanib as a potent anti-necroptosis agent for sepsis.

Cell death discovery

Yu L,Yang K,He X,Li M,Gao L,Zha Y

Fri Feb 10 00:00:00 UTC 2023

RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.

Molecular cell

Li Y,Huang J,Bao L,Zhu J,Duan W,Zheng H,Wang H,Jiang Y,Liu W,Zhang M,Yu Y,Yi C,Ji X

Thu Apr 20 00:00:00 UTC 2023

Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.

Environmental science and pollution research international

Zhu H,Kulyar MF,Ding Y,Yao W,Mo Q,Li J

Wed Mar 01 00:00:00 UTC 2023

Prognostic role and immune infiltration characteristics of EI24 in multiple cancer types.

Expert review of molecular diagnostics

Yang W,Zhou W,Zhao X,Duan L,Niu L,Zhang Y,Li Y,Wang X,Chen J,Fan A,Xie Q,Liu J,Han Y,Fan D,Hong L

Mon May 01 00:00:00 UTC 2023

Loss-of-function mutations in IQCN cause male infertility in humans and mice owing to total fertilization failure.

Molecular human reproduction

Wang Y,Chen G,Tang Z,Mei X,Lin C,Kang J,Lian J,Lu J,Liu Y,Lan F,Huang W,Zhang D

Fri Jun 30 00:00:00 UTC 2023

Loss-of-function mutations in IQCN cause male infertility in humans and mice owing to total fertilization failure.

Molecular human reproduction

Wang Y,Chen G,Tang Z,Mei X,Lin C,Kang J,Lian J,Lu J,Liu Y,Lan F,Huang W,Zhang D

Fri Jun 30 00:00:00 UTC 2023

Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.

Journal of medical virology

Tu W,Liu J,Qian F,Zhu L,Li M,Zheng H,Zhu C

Wed Mar 01 00:00:00 UTC 2023

Cytoskeletal protein SPTA1 mediating the decrease in erectile function induced by high-fat diet via Hippo signaling pathway.

Andrology

Chen Y,Wang L,Huang ZS,Feng JX,Li SX,Du ZJ,Zhang ZB,Liu J,Yang J,Hu ZM,Wang ZL,Chen J

Wed Mar 01 00:00:00 UTC 2023

Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation.

Free radical biology & medicine

Zhang B,Hou Q,Zhang X,Ma Y,Yuan J,Li S,Zhao X,Sun L,Wang H,Zheng H

Wed Feb 01 00:00:00 UTC 2023

TRAF6 Promotes PRMT5 Activity in a Ubiquitination-Dependent Manner.

Cancers

Liu L,Yin S,Gan W

Thu Apr 27 00:00:00 UTC 2023

Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.

Neural regeneration research

Huang LY,Ma JY,Song JX,Xu JJ,Hong R,Fan HD,Cai H,Wang W,Wang YL,Hu ZL,Shen JG,Qi SH

Mon May 01 00:00:00 UTC 2023

Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates.

Developmental cell

Fu Y,Jia X,Yuan J,Yang Y,Zhang T,Yu Q,Zhou J,Wang T

Mon Mar 13 00:00:00 UTC 2023

Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Ni Y,Chen Y,Jiang X,Pu T,Zhang L,Li S,Hu L,Bai B,Hu T,Yu L,Yang Y

Wed Feb 15 00:00:00 UTC 2023

Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling.

Pediatric research

Huang C,Wang W,Huang H,Jiang J,Ding Y,Li X,Ma J,Hou M,Pu X,Qian G,Lv H

Thu Jun 01 00:00:00 UTC 2023

Stimulation of functional recovery via neurorepair mechanisms by the traditional Japanese Kampo medicine, Ninjin'yoeito, and physical exercise in a rat ischemic stroke model.

Journal of ethnopharmacology

Tani A,Sakakima H,Otsuka S,Mizuno K,Nakanishi K,Norimatsu K,Takada S,Matsuoka T,Matsuzaki R,Nakakogawa T,Maruyama I

Fri Feb 10 00:00:00 UTC 2023

UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.

Biochimica et biophysica acta. Gene regulatory mechanisms

Hu X,Zou R,Zhang Z,Ji J,Li J,Huo XY,Liu D,Ge MX,Cui MK,Wu MZ,Li ZP,Wang Q,Zhang X,Zhang ZR

Thu Jun 01 00:00:00 UTC 2023

ZLN005 improves the survival of polymicrobial sepsis by increasing the bacterial killing via inducing lysosomal acidification and biogenesis in phagocytes.

Frontiers in immunology

Suzuki Y,Kami D,Taya T,Sano A,Ogata T,Matoba S,Gojo S

Mon Feb 27 00:00:00 UTC 2023

Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.

Molecular cancer research : MCR

Liao X,Li Z,Zheng H,Qian W,Zhang S,Chen S,Li X,Tang M,Xu Y,Yu R,Li M,Song L,Li J

Wed Jul 05 00:00:00 UTC 2023

Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.

Oncogene

Fang J,Zhang Y,Huang C,Lu R,Yu J,Chen R,Wang Y,Zhao X,Yu J,Huang J

Wed Mar 01 00:00:00 UTC 2023

The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.

Cell reports

Wen L,Yang X,Wu Z,Fu S,Zhan Y,Chen Z,Bi D,Shen Y

Tue Apr 25 00:00:00 UTC 2023

RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.

International journal of molecular sciences

Li L,Lv L,Xu JC,He Q,Chang N,Cui YY,Tao ZC,Zhu T,Qian LT

Wed Mar 15 00:00:00 UTC 2023

Fecal microbiota transplantation ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota in db/db mice.

BMJ open diabetes research & care

Chen L,Guo L,Feng S,Wang C,Cui Z,Wang S,Lu Q,Chang H,Hang B,Snijders AM,Mao JH,Lu Y,Ding D

Mon May 01 00:00:00 UTC 2023

Morusinol extracted from Morus alba induces cell cycle arrest and apoptosis via inhibition of DNA damage response in melanoma by CHK1 degradation through the ubiquitin-proteasome pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Guo L,Dong Z,Zhang X,Yang Y,Hu X,Ji Y,Li C,Wan S,Xu J,Liu C,Zhang Y,Liu L,Shi Y,Wu Z,Liu Y,Cui H

Thu Jun 01 00:00:00 UTC 2023

Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.

Cell death and differentiation

Qin J,Huang T,Wang Z,Zhang X,Wang J,Dang Q,Cui D,Wang X,Zhai Y,Zhao L,Lu G,Shao C,Li S,Liu H,Liu Z

Sun Jan 01 00:00:00 UTC 2023

MiR-216a-3p inhibits the proliferation and invasion of fibroblast-like synoviocytes by targeting dual-specificity phosphatase 5.

International journal of rheumatic diseases

Ni R,Liu H,Song G,Fu X,Deng B,Xu Z,Dai S,Huang G

Sat Apr 01 00:00:00 UTC 2023

IL-17C neutralization protects the kidney against acute injury and chronic injury.

EBioMedicine

Zhang F,Yin J,Liu L,Liu S,Zhang G,Kong Y,Wang Y,Wang N,Chen X,Wang F

Thu Jun 01 00:00:00 UTC 2023

Vitamin C promotes ACE2 degradation and protects against SARS-CoV-2 infection.

EMBO reports

Zuo Y,Zheng Z,Huang Y,He J,Zang L,Ren T,Cao X,Miao Y,Yuan Y,Liu Y,Ma F,Dai J,Tian S,Ding Q,Zheng H

Wed Apr 05 00:00:00 UTC 2023

Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis.

Asian journal of andrology

Wang XL,Li JM,Yuan SQ

Fri Apr 28 00:00:00 UTC 2023

Repurposing crizotinib to target RIPK1-dependent cell death.

International immunology

Yu Y,Li M,Fu S,He X,Hu X,Zhu G,Wang J,You X,Mou Y,Ye Z,Wei J,Zha Y

Mon May 08 00:00:00 UTC 2023

Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.

International immunopharmacology

Wu Q,Chen X,Qiao C,Cao X,Du Q,Yuan Y,Zuo Y,Miao Y,Zheng Z,Zhang T,Zang L,Yang X,Shi W,Xie Z,Xu Y,Wu D,Wen C,Zheng H

Sun Jan 01 00:00:00 UTC 2023

Porphyromonas gingivalis Outer Membrane Vesicles Promote Apoptosis via msRNA-Regulated DNA Methylation in Periodontitis.

Microbiology spectrum

Fan R,Zhou Y,Chen X,Zhong X,He F,Peng W,Li L,Wang X,Xu Y

Tue Feb 14 00:00:00 UTC 2023

LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei.

Nature communications

Zhu J,Chen K,Sun YH,Ye W,Liu J,Zhang D,Su N,Wu L,Kou X,Zhao Y,Wang H,Gao S,Kang L

Tue Feb 21 00:00:00 UTC 2023

Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling.

Nutrients

Xie Y,Shen F,He Y,Guo C,Yang R,Cao H,Pan Q,Fan J

Thu Mar 02 00:00:00 UTC 2023

Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment.

Proceedings of the National Academy of Sciences of the United States of America

Mun DJ,Goo BS,Suh BK,Hong JH,Woo Y,Kim SJ,Kim S,Lee SB,Won Y,Yoo JY,Cho E,Jang EJ,Nhung TTM,Triet HM,An H,Lee H,Nguyen MD,Park SY,Baek ST,Park SK

Tue Feb 21 00:00:00 UTC 2023

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.

Cancers

Caballero-Ruiz B,Gkotsi DS,Ollerton H,Morales-Alcala CC,Bordone R,Jenkins GML,Di Magno L,Canettieri G,Riobo-Del Galdo NA

Fri Jan 06 00:00:00 UTC 2023

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.

The Journal of clinical investigation

Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L

Fri Apr 01 00:00:00 UTC 2022

The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.

Carcinogenesis

Zeng Q,Jin F,Qian H,Chen H,Wang Y,Zhang D,Wei Y,Chen T,Guo B,Chai C

Thu Mar 24 00:00:00 UTC 2022

A comparative study of Mesenchymal Stem Cells transplantation approach to antagonize age-associated ovarian hypofunction with consideration of safety and efficiency.

Journal of advanced research

Wang L,Mei Q,Xie Q,Li H,Su P,Zhang L,Li K,Ma D,Chen G,Li J,Xiang W

Sun May 01 00:00:00 UTC 2022

A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology.

Nature cell biology

Zhou J,Duan M,Wang X,Zhang F,Zhou H,Ma T,Yin Q,Zhang J,Tian F,Wang G,Yang C

Fri Apr 01 00:00:00 UTC 2022

Trichodimerol inhibits inflammation through suppression of the nuclear transcription factor-kappaB/NOD-like receptor thermal protein domain associated protein 3 signaling pathway.

Frontiers in microbiology

Huo XY,Lei LR,Guo WX,Hu YJ,Kuang QX,Liu MD,Peng W,Dai YF,Wang D,Gu YC,Guo DL,Deng Y

Tue Sep 03 00:00:00 UTC 2024

KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.

Cancer letters

Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y

Tue Nov 01 00:00:00 UTC 2022

KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.

Cancer letters

Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y

Tue Nov 01 00:00:00 UTC 2022

6-O-desulfated heparin attenuates myocardial ischemia/reperfusion injury in mice through the regulation of miR-199a-5p/klotho axis.

Glycoconjugate journal

Wang Y,Li T,Li N,Huang C,Xiong X,Xie X,Wu M,Wang L,Jiang J

Thu Dec 01 00:00:00 UTC 2022

Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling.

Particle and fibre toxicology

Ribeiro LW,Pietri M,Ardila-Osorio H,Baudry A,Boudet-Devaud F,Bizingre C,Arellano-Anaya ZE,Haeberlé AM,Gadot N,Boland S,Devineau S,Bailly Y,Kellermann O,Bencsik A,Schneider B

Fri Jul 15 00:00:00 UTC 2022

The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma.

Frontiers in cell and developmental biology

Parkinson LM,Gillen SL,Woods LM,Chaytor L,Marcos D,Ali FR,Carroll JS,Philpott A

Wed Nov 27 00:00:00 UTC 2024

Trehalose prevents glyphosate-induced testicular damage in roosters via its antioxidative properties.

Research in veterinary science

Chen K,Liu JB,Tie CZ,Wang L

Tue Dec 20 00:00:00 UTC 2022

Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis.

Nature communications

Wang Z,Sun Y,Lou F,Bai J,Zhou H,Cai X,Sun L,Yin Q,Tang S,Wu Y,Fan L,Xu Z,Wang H,Hu X,Wang H

Mon Dec 19 00:00:00 UTC 2022

PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK.

Cells

Zi J,Xu J,Luo J,Yang X,Zhen Z,Li X,Hu D,Guo Y,Guo H,Ding X,Zhang L

Tue Oct 11 00:00:00 UTC 2022

Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.

Frontiers in pharmacology

Li J,Jiang Y,Dai Q,Yu Y,Lv X,Zhang Y,Liao X,Ao L,Hu G,Meng J,Peng Z,Tao L,Xie Y

Mon Apr 24 00:00:00 UTC 2023

Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.

Journal of medicinal chemistry

Zhang S,Chen X,Wu C,Xu H,Xie X,Feng M,Hu S,Bai H,Gao F,Tong L,Ding J,Liu H,Xie Z,Wang J

Thu Jun 09 00:00:00 UTC 2022

Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.

Biochemical and biophysical research communications

Huang XT,Zheng Y,Long G,Peng WT,Wan QQ

Thu Jun 30 00:00:00 UTC 2022

Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.

Frontiers in pharmacology

Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H

Wed Apr 13 00:00:00 UTC 2022

Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.

International immunopharmacology

Wang X,Duan C,Li Y,Lu H,Guo K,Ge X,Chen T,Shang Y,Liu H,Zhang D

Sat Oct 01 00:00:00 UTC 2022

Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.

International immunopharmacology

Wang X,Duan C,Li Y,Lu H,Guo K,Ge X,Chen T,Shang Y,Liu H,Zhang D

Sat Oct 01 00:00:00 UTC 2022

N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways.

Frontiers in pharmacology

Huang LJ,Wang YM,Gong LQ,Hu C,Gui Y,Zhang C,Tan X,Yu XK,Liao YL,Luo Y,Tang YQ,Dai YF,Deng Y,Wang D,Guo DL

Sat Jul 16 00:00:00 UTC 2022

N⁶-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming.

Theranostics

Zhang K,Zhang T,Yang Y,Tu W,Huang H,Wang Y,Chen Y,Pan K,Chen Z

Fri Jul 15 00:00:00 UTC 2022

ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.

Journal of molecular biology

Chen G,Yang Y,Wu QJ,Cao L,Ruan W,Shao C,Jiang L,Tang P,Ma S,Jiang A,Wang Z,Wu K,Zhang QC,Fu XD,Zhou Y

Fri Apr 15 00:00:00 UTC 2022

Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner.

Frontiers in immunology

Ran XH,Zhu JW,Chen YY,Ni RZ,Mu D

Tue Aug 30 00:00:00 UTC 2022

Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.

Cell death & disease

Xiao J,Zhang L,Yi H,Zou L,Mo J,Xue F,Zheng J,Huang Y,Lu H,Wu H,Xue P,Zhang X,He L,Li Z,Pang S,Qiao G,Duan Q,Zhu F

Tue Sep 27 00:00:00 UTC 2022

Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination.

Genes & diseases

Yuan G,Yang S,Yang S

Thu Sep 01 00:00:00 UTC 2022

STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages.

Oxidative medicine and cellular longevity

Wu XY,Chen YJ,Liu CA,Gong JH,Xu XS

Thu Mar 24 00:00:00 UTC 2022

Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors.

eLife

Kim SJ,Woo Y,Kim HJ,Goo BS,Nhung TTM,Lee SA,Suh BK,Mun DJ,Kim JH,Park SK

Mon Apr 25 00:00:00 UTC 2022

Protocol for isolation and proteostatic analysis of sub-populations of spermatogenic cells in mouse.

STAR protocols

Zou Q,Yang L,Qi H

Fri Jun 17 00:00:00 UTC 2022

HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.

Veterinary research communications

Lu L,Jin C,Dong PF,Wang ZY

Thu Dec 01 00:00:00 UTC 2022

SIX1 Predicts Poor Prognosis and Facilitates the Progression of Non-small Lung Cancer via Activating the Notch Signaling Pathway.

Journal of Cancer

Huang S,Lin W,Wang L,Gao Y,Yuan X,Zhang P,Chen Y,Chu Q

Tue Jan 25 00:00:00 UTC 2022

Seneca Valley Virus Induces DHX30 Cleavage to Antagonize Its Antiviral Effects.

Journal of virology

Wen W,Zheng Z,Wang H,Zhao Q,Yin M,Chen H,Li X,Qian P

Wed Sep 14 00:00:00 UTC 2022

ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.

Cell biology international

Li Y,Tang J,Li J,Du Y,Bai F,Yang L,Li X,Jin X,Wang T

Wed Jun 01 00:00:00 UTC 2022

Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.

Veterinary microbiology

Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J

Tue Mar 01 00:00:00 UTC 2022

Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Wang YF,Chang YY,Zhang XM,Gao MT,Zhang QL,Li X,Zhang L,Yao WF

Sun May 01 00:00:00 UTC 2022

Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.

Cell research

Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H

Sat Oct 01 00:00:00 UTC 2022

Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.

Cell research

Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H

Sat Oct 01 00:00:00 UTC 2022

Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification.

Journal of translational medicine

Lyu F,Li Y,Yan Z,He Q,Cheng L,Zhang P,Liu B,Liu C,Song Y,Xing Y

Tue May 10 00:00:00 UTC 2022

Asparaginyl endopeptidase protects against podocyte injury in diabetic nephropathy through cleaving cofilin-1.

Cell death & disease

Lei C,Li M,Qiu Y,Xie Y,Hao Z,Yin X,Zhang Z,Su H,Yang L,Lin J,Hammes HP,Zhang C

Fri Feb 25 00:00:00 UTC 2022

Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1.

Autophagy

Shao T,Ke H,Liu R,Xu L,Han S,Zhang X,Dang Y,Jiao X,Li W,Chen ZJ,Qin Y,Zhao S

Mon Aug 01 00:00:00 UTC 2022

SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1.

Cellular & molecular immunology

Zhang S,Wang J,Wang L,Aliyari S,Cheng G

Mon Aug 01 00:00:00 UTC 2022

4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects.

FEBS open bio

Birus R,El-Awaad E,Ballentin L,Alchab F,Aichele D,Ettouati L,Götz C,Le Borgne M,Jose J

Tue Feb 01 00:00:00 UTC 2022

Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity.

Molecular cell

Li Y,Huang J,Zhu J,Bao L,Wang H,Jiang Y,Tian K,Wang R,Zheng H,Duan W,Lai W,Yi X,Zhu Y,Guo T,Ji X

Thu Oct 20 00:00:00 UTC 2022

DELE1 tracks perturbed protein import and processing in human mitochondria.

Nature communications

Fessler E,Krumwiede L,Jae LT

Wed Apr 06 00:00:00 UTC 2022

Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma.

Cells

Li X,Chen Q,Liu J,Lai S,Zhang M,Zhen T,Hu H,Gao X,Wong AST,Zeng JZ

Thu Dec 01 00:00:00 UTC 2022

Dynamic control of chromatin-associated m⁶A methylation regulates nascent RNA synthesis.

Molecular cell

Xu W,He C,Kaye EG,Li J,Mu M,Nelson GM,Dong L,Wang J,Wu F,Shi YG,Adelman K,Lan F,Shi Y,Shen H

Thu Mar 17 00:00:00 UTC 2022

Metformin alleviates the cognitive impairment caused by aluminum by improving energy metabolism disorders in mice.

Biochemical pharmacology

Song Y,Liu Z,Zhu X,Hao C,Hao W,Wu S,Yang J,Lu X,Jin C

Mon Aug 01 00:00:00 UTC 2022

Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.

Frontiers in cardiovascular medicine

Cui WW,Ye C,Wang KX,Yang X,Zhu PY,Hu K,Lan T,Huang LY,Wang W,Gu B,Yan C,Ma P,Qi SH,Luo L

Sat May 07 00:00:00 UTC 2022

Alpha-synuclein/MPP⁺ mediated activation of NLRP3 inflammasome through microtubule-driven mitochondrial perinuclear transport.

Biochemical and biophysical research communications

Yang X,Ma H,Yv Q,Ye F,He Z,Chen S,Keram A,Li W,Zhu M

Sat Feb 26 00:00:00 UTC 2022

Alpha-synuclein/MPP⁺ mediated activation of NLRP3 inflammasome through microtubule-driven mitochondrial perinuclear transport.

Biochemical and biophysical research communications

Yang X,Ma H,Yv Q,Ye F,He Z,Chen S,Keram A,Li W,Zhu M

Sat Feb 26 00:00:00 UTC 2022

Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function.

Neural regeneration research

Wu MY,Zou WJ,Yu P,Yang Y,Li SJ,Liu Q,Xie J,Chen SQ,Lin WJ,Tang Y

Sat Oct 01 00:00:00 UTC 2022

E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.

Immunology

Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y

Tue Nov 01 00:00:00 UTC 2022

E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.

Immunology

Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y

Tue Nov 01 00:00:00 UTC 2022

E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.

Immunology

Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y

Tue Nov 01 00:00:00 UTC 2022

E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.

Immunology

Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y

Tue Nov 01 00:00:00 UTC 2022

Rare POLN mutations confer risk for familial nasopharyngeal carcinoma through weakened Epstein-Barr virus lytic replication.

EBioMedicine

Xiao RW,Wang F,Wang TM,Zhang JB,Wu ZY,Deng CM,Liao Y,Zhou T,Yang DW,Dong SQ,Xue WQ,He YQ,Zheng XH,Li XZ,Zhang PF,Zhang SD,Hu YZ,Liu YY,Xia YF,Gao S,Mu JB,Feng L,Jia WH

Sat Oct 01 00:00:00 UTC 2022

Hexokinase 1 cellular localization regulates the metabolic fate of glucose.

Molecular cell

De Jesus A,Keyhani-Nejad F,Pusec CM,Goodman L,Geier JA,Stoolman JS,Stanczyk PJ,Nguyen T,Xu K,Suresh KV,Chen Y,Rodriguez AE,Shapiro JS,Chang HC,Chen C,Shah KP,Ben-Sahra I,Layden BT,Chandel NS,Weinberg SE,Ardehali H

Thu Apr 07 00:00:00 UTC 2022

miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.

Molecular biology reports

Xu H,Cui Y,Liu X,Zheng X,Liu J,Hu X,Gao F,Hu X,Li M,Wei X,Gao Y,Zhao Y

Tue Mar 01 00:00:00 UTC 2022

The identification of alternative oxidase in intermediate host snails of Schistosoma and its potential role in protecting Oncomelania hupensis against niclosamide-induced stress.

Parasites & vectors

Jiang N,Li SZ,Zhang YW,Habib MR,Xiong T,Xu S,Dong H,Zhao QP

Mon Mar 21 00:00:00 UTC 2022

Construction of Artificial Ovaries with Decellularized Porcine Scaffold and Its Elicited Immune Response after Xenotransplantation in Mice.

Journal of functional biomaterials

Wu T,Gao YY,Tang XN,Zhang JJ,Wang SX

Wed Sep 28 00:00:00 UTC 2022

BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells.

BMC oral health

Liu C,Yu J,Liu B,Liu M,Song G,Zhu L,Peng B

Thu Nov 24 00:00:00 UTC 2022

Resveratrol Synergistically Promotes BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells.

Stem cells international

Wang Y,Xia C,Chen Y,Jiang T,Hu Y,Gao Y

Fri Aug 05 00:00:00 UTC 2022

D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia.

iScience

Florio E,Serra M,Lewis RG,Kramár E,Freidberg M,Wood M,Morelli M,Borrelli E

Fri Oct 21 00:00:00 UTC 2022

LATS1 is a central signal transmitter for achieving full type-I interferon activity.

Science advances

Zuo Y,He J,Liu S,Xu Y,Liu J,Qiao C,Zang L,Sun W,Yuan Y,Zhang H,Chen X,Jin L,Miao Y,Huang F,Ren T,Wang J,Qian F,Zhu C,Zhang W,Liu Y,Xu G,Ma F,Zheng H

Fri Apr 08 00:00:00 UTC 2022

The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).

Biochemical pharmacology

Yang Y,Xiao H,Lin Z,Chen R,Li S,Li C,Sun X,Hei Z,Gong W,Huang H

Thu Dec 01 00:00:00 UTC 2022

METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability.

Nucleic acids research

Chen L,Zhang C,Ma W,Huang J,Zhao Y,Liu H

Fri Nov 11 00:00:00 UTC 2022

MEIG1 determines the manchette localization of IFT20 and IFT88, two intraflagellar transport components in male germ cells.

Developmental biology

Yap YT,Shi L,Zhang D,Huang Q,Siddika F,Wang Z,Li W,Zhang Z

Sun May 01 00:00:00 UTC 2022

Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.

Frontiers in pharmacology

Tan Z,Si Y,Yu Y,Ding J,Huang L,Xu Y,Zhang H,Lu Y,Wang C,Yu B,Yuan L

Sat Jul 16 00:00:00 UTC 2022

Osteopontin is required for the maintenance of leukemia stem cells in acute myeloid leukemia.

Biochemical and biophysical research communications

Zhou J,Chen X,Zhou P,Sun X,Chen Y,Li M,Chu Y,Zhou J,Hu X,Luo Y,Yuan W,Wang G

Sat Apr 16 00:00:00 UTC 2022

Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.

Biochimica et biophysica acta. Molecular cell research

Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L

Tue Feb 01 00:00:00 UTC 2022

Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood-Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight Junction Protein Reduction in Rat Stroke Model.

Frontiers in cellular neuroscience

Huang LY,Song JX,Cai H,Wang PP,Yin QL,Zhang YD,Chen J,Li M,Song JJ,Wang YL,Luo L,Wang W,Qi SH

Tue Mar 22 00:00:00 UTC 2022

TRIM67 Suppresses TNFalpha-Triggered NF-kB Activation by Competitively Binding Beta-TrCP to IkBa.

Frontiers in immunology

Fan W,Liu X,Zhang J,Qin L,Du J,Li X,Qian S,Chen H,Qian P

Mon May 02 00:00:00 UTC 2022

Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.

Cell death discovery

Zhou Y,Yong H,Cui W,Chu S,Li M,Li Z,Bai J,Zhang H

Mon Apr 11 00:00:00 UTC 2022

Secondary structure RNA elements control the cleavage activity of DICER.

Nature communications

Nguyen TD,Trinh TA,Bao S,Nguyen TA

Tue Apr 19 00:00:00 UTC 2022

Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.

Redox biology

Xu Z,Xu J,Sun S,Lin W,Li Y,Lu Q,Li F,Yang Z,Lu Y,Liu W

Mon Aug 01 00:00:00 UTC 2022

Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.

Cell death & disease

Zheng ZY,Chu MY,Lin W,Zheng YQ,Xu XE,Chen Y,Liao LD,Wu ZY,Wang SH,Li EM,Xu LY

Wed May 25 00:00:00 UTC 2022

MicroRNA-223-3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1).

Toxicology

Zhao S,Tan Y,Qin J,Xu H,Liu L,Wan H,Zhang C,Fan W,Qu S

Thu Jun 30 00:00:00 UTC 2022

Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.

Frontiers in immunology

Li L,Chen X,Lv M,Cheng Z,Liu F,Wang Y,Zhou A,Liu J,Zhao X

Tue Jul 19 00:00:00 UTC 2022

MiR-15p-5p Mediates the Coordination of ICAM-1 and FAK to Promote Endothelial Cell Proliferation and Migration.

Inflammation

Gu W,Zhang L,Zhang X,Wang B,Shi X,Hu K,Ye Y,Liu G

Wed Jun 01 00:00:00 UTC 2022

iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.

Oncogene

Zhao D,Zheng S,Wang X,Liu H,Zhao K,Li L,Hu Y

Tue Mar 01 00:00:00 UTC 2022

Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.

Evidence-based complementary and alternative medicine : eCAM

Wu M,Kang Q,Kang Y,Tong Y,Yang T,Fan Y

Sat Dec 10 00:00:00 UTC 2022

Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.

Frontiers in cellular neuroscience

Wang Y,Luo K,Li J,Liao Y,Liao C,Chen WS,Chen M,Ao L

Sat Jul 16 00:00:00 UTC 2022

Splicing factor BUD31 promotes ovarian cancer progression through sustaining the expression of anti-apoptotic BCL2L12.

Nature communications

Wang Z,Wang S,Qin J,Zhang X,Lu G,Liu H,Guo H,Wu L,Shender VO,Shao C,Kong B,Liu Z

Fri Oct 21 00:00:00 UTC 2022

Neddylation is essential for β-catenin degradation in Wnt signaling pathway.

Cell reports

Wang B,Wang T,Zhu H,Yan R,Li X,Zhang C,Tao W,Ke X,Hao P,Qu Y

Tue Mar 22 00:00:00 UTC 2022

Identification and Characterization of BmNPV m6A Sites and Their Possible Roles During Viral Infection.

Frontiers in immunology

Zhang X,Zhang Y,Pan J,Gong C,Hu X

Fri Apr 08 00:00:00 UTC 2022

Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.

Molecular cell

Zhou Q,Hao B,Cao X,Gao L,Yu Z,Zhao Y,Zhu M,Zhong G,Chi F,Dai X,Mao J,Zhu Y,Rong P,Chen L,Bai X,Ye C,Chen S,Liang T,Li L,Feng XH,Tan M,Zhao B

Thu Dec 15 00:00:00 UTC 2022

Damage of uremic myocardium by p-cresyl sulfate and the ameliorative effect of Klotho by regulating SIRT6 ubiquitination.

Toxicology letters

Chen C,Xie C,Xiong Y,Wu H,Wu L,Zhu J,Xing C,Mao H

Mon Aug 15 00:00:00 UTC 2022

Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.

Frontiers in oncology

Han T,Tong J,Wang M,Gan Y,Gao B,Chen J,Liu Y,Hao Q,Zhou X

Sat Jul 16 00:00:00 UTC 2022

Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers.

Cell & bioscience

Bai L,Tu WY,Xiao Y,Zhang K,Shen C

Tue Aug 30 00:00:00 UTC 2022

Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly.

Cell proliferation

Cao Y,Zhu X,Zhen P,Tian Y,Ji D,Xue K,Yan W,Chai J,Liu H,Wang W

Thu Dec 01 00:00:00 UTC 2022

GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis.

Oncogenesis

Zhao C,Yu H,Fan X,Niu W,Fan J,Sun S,Gong M,Zhao B,Fang Z,Chen X

Mon May 23 00:00:00 UTC 2022

D609 inhibition of phosphatidylcholine-specific phospholipase C attenuates prolonged insulin stimulation-mediated GLUT4 downregulation in 3T3-L1 adipocytes.

Journal of physiology and biochemistry

Ma J,Zhang X,Song Y,Qin Y,Tan Y,Zheng L,Cheng B,Xi X

Sun May 01 00:00:00 UTC 2022

O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.

International journal of molecular sciences

Cao Y,Zhang M,Li Y,Lu J,Zhou W,Li X,Shi H,Xu B,Li S

Tue Nov 22 00:00:00 UTC 2022

The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.

iScience

Magusto J,Beaupère C,Afonso MB,Auclair M,Delaunay JL,Soret PA,Courtois G,Aït-Slimane T,Housset C,Jéru I,Fève B,Ratziu V,Rodrigues CMP,Gautheron J

Fri Oct 21 00:00:00 UTC 2022

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Fri Sep 27 00:00:00 UTC 2024

Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.

The EMBO journal

Gruijs da Silva LA,Simonetti F,Hutten S,Riemenschneider H,Sternburg EL,Pietrek LM,Gebel J,Dötsch V,Edbauer D,Hummer G,Stelzl LS,Dormann D

Tue Apr 19 00:00:00 UTC 2022

BmCPV-Derived Circular DNA vcDNA-S7 Mediated by Bombyx mori Reverse Transcriptase (RT) Regulates BmCPV Infection.

Frontiers in immunology

Zhu M,Pan J,Tong X,Qiu Q,Zhang X,Zhang Y,Sun S,Feng Y,Xue R,Cao G,Hu X,Gong C

Fri Apr 08 00:00:00 UTC 2022

Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.

Epilepsia

Lin JR,Cheng JF,Liu YT,Hsu TR,Lin KM,Chen C,Lin CL,Tsai MH,Tsai JW

Sun May 01 00:00:00 UTC 2022

Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.

Epilepsia

Lin JR,Cheng JF,Liu YT,Hsu TR,Lin KM,Chen C,Lin CL,Tsai MH,Tsai JW

Sun May 01 00:00:00 UTC 2022

Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication.

Chemico-biological interactions

Wang Q,Chen W,Zhang B,Gao Z,Zhang Q,Deng H,Han L,Shen XL

Fri Feb 25 00:00:00 UTC 2022

Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway.

Lipids in health and disease

Xiong H,Ye J,Xie K,Hu W,Xu N,Yang H

Thu Dec 29 00:00:00 UTC 2022

Worenine Prevents Solar Ultraviolet-Induced Sunburn by Inhibiting JNK2.

Frontiers in pharmacology

Xiao J,Lu H,Ma T,Ni X,Chang T,Liu M,Li N,Lu P,Ke C,Tian Q,Zou L,Wang F,Wang W,Zhang L,Yuan P,Liu L,Zhang J,Shi F,Duan Q,Zhu F

Fri Aug 19 00:00:00 UTC 2022

Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.

Cells

Zrimšek M,Kuchaříková H,Draganić K,Dobrovolná P,Heiss Spornberger V,Winkelmayer L,Hassler MR,Lochmanová G,Zdráhal Z,Egger G

Tue Aug 02 00:00:00 UTC 2022

Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.

International immunopharmacology

Yao TT,Zhang Y,He RL,Lv X,He YJ,Li MY,Han YY,Long LZ,Jiang GL,Cheng XY,Hu GY,Li QB,Tao LJ,Meng J

Thu Dec 01 00:00:00 UTC 2022

Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.

International journal of molecular sciences

Lan T,Zhang K,Lin F,He Q,Wu S,Xu Z,Zhang Y,Quan F

Wed Aug 03 00:00:00 UTC 2022

Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.

Open biology

Xue J,Liao Q,Luo M,Hua C,Zhao J,Yu G,Chen X,Li X,Zhang X,Ran R,Lu F,Wang Y,Qiao L

Fri Apr 01 00:00:00 UTC 2022

Brown adipose tissue involution associated with progressive restriction in progenitor competence.

Cell reports

Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB

Tue Apr 12 00:00:00 UTC 2022

Acetylation of fructose-bisphosphate aldolase-mediated glycolysis is essential for Bombyx mori nucleopolyhedrovirus infection.

Microbial pathogenesis

Gao X,Xu S,Mo Y,Zhu Y,Chen X,Miao M,Quan Y,Yu W

Thu Sep 01 00:00:00 UTC 2022

Inhibiting STAT5 significantly attenuated Ang II-induced cardiac dysfunction and inflammation.

European journal of pharmacology

Jin G,Wang L,Ma J

Sat Jan 15 00:00:00 UTC 2022

TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.

International journal of molecular sciences

Gu H,Zhu S,Peng C,Wei Z,Shen Y,Yuan C,Yang H,Cui H,Yang L

Mon Sep 05 00:00:00 UTC 2022

SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner.

Emerging microbes & infections

Zhou YQ,Wang K,Wang XY,Cui HY,Zhao Y,Zhu P,Chen ZN

Thu Dec 01 00:00:00 UTC 2022

Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.

Molecular and cellular endocrinology

Yan H,Li Q,Li M,Zou X,Bai N,Yu Z,Zhang J,Zhang D,Zhang Q,Wang J,Jia H,Wu Y,Hou Z

Sat Jan 01 00:00:00 UTC 2022

Antagonistic action of a synthetic androgen ligand mediated by chromatin remodeling in a human prostate cancer cell line.

Biochemical and biophysical research communications

Sawada T,Kanemoto Y,Amano R,Hayakawa A,Kurokawa T,Mori J,Kato S

Tue Jul 05 00:00:00 UTC 2022

Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis.

Annals of translational medicine

Wu F,Yuan X,Liu W,Meng L,Li X,Gao X,Zhou S,Fang L,Yu D

Sun May 01 00:00:00 UTC 2022

Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.

iScience

Vabret N,Najburg V,Solovyov A,Gopal R,McClain C,Šulc P,Balan S,Rahou Y,Beauclair G,Chazal M,Varet H,Legendre R,Sismeiro O,Sanchez David RY,Chauveau L,Jouvenet N,Markowitz M,van der Werf S,Schwartz O,Tangy F,Bhardwaj N,Greenbaum BD,Komarova AV

Fri Jul 15 00:00:00 UTC 2022

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.

Nature metabolism

Zhang CS,Li M,Wang Y,Li X,Zong Y,Long S,Zhang M,Feng JW,Wei X,Liu YH,Zhang B,Wu J,Zhang C,Lian W,Ma T,Tian X,Qu Q,Yu Y,Xiong J,Liu DT,Wu Z,Zhu M,Xie C,Wu Y,Xu Z,Yang C,Chen J,Huang G,He Q,Huang X,Zhang L,Sun X,Liu Q,Ghafoor A,Gui F,Zheng K,Wang W,Wang ZC,Yu Y,Zhao Q,Lin SY,Wang ZX,Piao HL,Deng X,Lin SC

Sat Oct 01 00:00:00 UTC 2022

DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway.

Science signaling

Liu L,Dai X,Yin S,Liu P,Hill EG,Wei W,Gan W

Tue Jan 04 00:00:00 UTC 2022

TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.

Frontiers in immunology

Shi B,Hao Y,Li W,Dong H,Xu M,Gao P

Thu May 19 00:00:00 UTC 2022

Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.

Theranostics

Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T

Thu Mar 10 00:00:00 UTC 2022

SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.

Cancer letters

Li TJ,Jin KZ,Li H,Ye LY,Li PC,Jiang B,Lin X,Liao ZY,Zhang HR,Shi SM,Lin MX,Fei QL,Xiao ZW,Xu HX,Liu L,Yu XJ,Wu WD

Fri Apr 01 00:00:00 UTC 2022

C3/C3aR inhibition alleviates GMH-IVH-induced hydrocephalus by preventing microglia-astrocyte interactions in neonatal rats.

Neuropharmacology

Tang J,Jila S,Luo T,Zhang B,Miao H,Feng H,Chen Z,Zhu G

Tue Mar 01 00:00:00 UTC 2022

STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment.

Cancer cell international

Pu Z,Liu J,Liu Z,Peng F,Zhu Y,Wang X,He J,Yi P,Hu X,Fan X,Chen J

Wed Oct 12 00:00:00 UTC 2022

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.

Cell reports. Medicine

Singh A,D'Amico D,Andreux PA,Fouassier AM,Blanco-Bose W,Evans M,Aebischer P,Auwerx J,Rinsch C

Tue May 17 00:00:00 UTC 2022

The involvement of the primo vascular system in local enteritis and its modification by electroacupuncture.

Frontiers in immunology

Nan S,Wan J,Lei Q,Wang X,Ma N,Yin R,Zhu J,Ding M,Ding Y

Tue Jan 31 00:00:00 UTC 2023

UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.

EMBO reports

Song P,Yang W,Lou KF,Dong H,Zhang H,Wang B,Chen D

Mon Nov 07 00:00:00 UTC 2022

Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export.

Molecular brain

Nakashima N,Nakashima A,Nakashima K,Takano M

Fri Nov 04 00:00:00 UTC 2022

Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.

Frontiers in endocrinology

Wang C,Sun Y

Tue Apr 19 00:00:00 UTC 2022

Analysis of the Effects of Ninjin'yoeito on Physical Frailty in Mice.

International journal of molecular sciences

Otsuka S,Fukumaru K,Tani A,Takada S,Kikuchi K,Norimatsu K,Matsuzaki R,Matsuoka T,Sakakima H,Omiya Y,Mizuno K,Matsubara Y,Maruyama I

Fri Sep 23 00:00:00 UTC 2022

Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease.

Acta pharmacologica Sinica

Yin F,Zheng PQ,Zhao LQ,Wang YZ,Miao NJ,Zhou ZL,Cheng Q,Chen PP,Xie HY,Li JY,Ni JY,Zhou L,Zhang W,Wang XX,Liu J,Lu LM

Sat Jan 01 00:00:00 UTC 2022

Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhou Y,Lu Q

Thu Sep 01 00:00:00 UTC 2022

Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.

Frontiers in cellular neuroscience

Cheng L,Su Y,Zhi K,Xie Y,Zhang C,Meng X

Tue Oct 11 00:00:00 UTC 2022

Alternative polyadenylation by sequential activation of distal and proximal PolyA sites.

Nature structural & molecular biology

Tang P,Yang Y,Li G,Huang L,Wen M,Ruan W,Guo X,Zhang C,Zuo X,Luo D,Xu Y,Fu XD,Zhou Y

Sat Jan 01 00:00:00 UTC 2022

Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.

The Science of the total environment

Zhou J,Zeng L,Zhang Y,Wang M,Li Y,Jia Y,Wu L,Su P

Tue Nov 15 00:00:00 UTC 2022

Progerin-expressing endothelial cells are unable to adapt to shear stress.

Biophysical journal

Danielsson BE,Peters HC,Bathula K,Spear LM,Noll NA,Dahl KN,Conway DE

Tue Feb 15 00:00:00 UTC 2022

A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.

Bioorganic chemistry

Yao S,Yin J,Liu W,Li Y,Huang J,Qi C,Hu Z,Tong Q,Gu L,Zhang Y

Sat Oct 01 00:00:00 UTC 2022

Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.

Journal of experimental & clinical cancer research : CR

Yang W,Li J,Zhang M,Yu H,Zhuang Y,Zhao L,Ren L,Gong J,Bi H,Zeng L,Xue Y,Yang J,Zhao Y,Wang S,Gao S,Fu Z,Li D,Zhang J,Wang T,Shan M,Tang B,Li X

Fri Feb 18 00:00:00 UTC 2022

Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.

Environmental toxicology

Hao W,Zhu X,Liu Z,Song Y,Wu S,Lu X,Yang J,Jin C

Wed Jun 01 00:00:00 UTC 2022

Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression.

Journal of molecular cell biology

Li Y,Yang C,Wang H,Zhao L,Kong Q,Cang Y,Zhao S,Lv L,Li Y,Mao B,Ma P

Tue Apr 05 00:00:00 UTC 2022

Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.

Neuropharmacology

Yang C,Kang F,Huang X,Zhang W,Wang S,Han M,Zhang Z,Li J

Thu Dec 01 00:00:00 UTC 2022

The deubiquitinase USP10 protects pancreatic cancer cells from endoplasmic reticulum stress.

NPJ precision oncology

Bhattacharya U,Thavathiru E,Neizer-Ashun F,Xu C,Gatalica Z,Dwivedi SKD,Dey A,Mukherjee P,Bhattacharya R

Wed Dec 21 00:00:00 UTC 2022

Expression pattern of alkB homolog 5 in goat testis and its role in spermatogonial stem cells.

Cell and tissue research

Liu Z,Cai Y,Deng M,Li D,Leng Q,Shi L,Tang Y,Wang F,Wan Y

Sat Jan 01 00:00:00 UTC 2022

DNA methylation status of DNAJA4 is essential for human erythropoiesis.

Epigenomics

Zhang H,Xue F,Zhao H,Chen L,Wang T,Wu X

Sat Oct 01 00:00:00 UTC 2022

The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.

The Journal of cell biology

Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E

Mon Dec 05 00:00:00 UTC 2022

The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.

The Journal of cell biology

Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E

Mon Dec 05 00:00:00 UTC 2022

Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment.

Cell reports. Medicine

Mei Z,Yang T,Liu Y,Gao Y,Hou Z,Zhuang Q,He D,Zhang X,Tan Q,Zhu X,Qin Y,Chen X,Xu C,Bian C,Wang X,Wang C,Wu D,Huang S,Li Z

Tue May 17 00:00:00 UTC 2022

Genome-Wide Analysis of the Indispensable Role of Non-structural Proteins in the Replication of SARS-CoV-2.

Frontiers in microbiology

Jin Y,Ouyang M,Yu T,Zhuang J,Wang W,Liu X,Duan F,Guo D,Peng X,Pan JA

Sat Jul 16 00:00:00 UTC 2022

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy.

Nature communications

Zhao M,Wei H,Li C,Zhan R,Liu C,Gao J,Yi Y,Cui X,Shan W,Ji L,Pan B,Cheng S,Song M,Sun H,Jiang H,Cai J,Garcia-Barrio MT,Chen YE,Meng X,Dong E,Wang DW,Zheng L

Fri Apr 01 00:00:00 UTC 2022

Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair.

Science advances

Liu L,Lin B,Yin S,Ball LE,Delaney JR,Long DT,Gan W

Fri Dec 09 00:00:00 UTC 2022

Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.

International immunopharmacology

He J,Liu L,Liu X,Chen H,Liu K,Huang N,Wang Y

Thu Dec 01 00:00:00 UTC 2022

The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Cheng G,Zhang S,Lv M,Qi C,Fan R,Guo X,Liu J,Zhao X

Mon Aug 01 00:00:00 UTC 2022

Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.

International journal of molecular sciences

Han M,Li Y,Guo Y,Zhu W,Jiang J

Sun Nov 13 00:00:00 UTC 2022

Multiple ciliary localization signals control INPP5E ciliary targeting.

eLife

Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR

Mon Sep 05 00:00:00 UTC 2022

Multiple ciliary localization signals control INPP5E ciliary targeting.

eLife

Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR

Mon Sep 05 00:00:00 UTC 2022

Isolation of five different primary cell types from a single sample of human skin.

STAR protocols

Kabacik S,Lowe D,Cohen H,Felton S,Spitzer J,Raj K

Fri Jun 17 00:00:00 UTC 2022

Critical Role of Cathepsin L/V in Regulating Endothelial Cell Senescence.

Biology

Li C,Liu Z,Chen M,Zhang L,Shi R,Zhong H

Mon Dec 26 00:00:00 UTC 2022

Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.

International immunopharmacology

Liu W,Liu M,Xiong H,Xia L,Yang Q,Chen M,Cai Y,Li S

Thu Dec 01 00:00:00 UTC 2022

H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.

Nucleic acids research

Li Z,Zhang X,Xie S,Liu X,Fei C,Huang X,Tang Y,Zhou LQ

Fri Jul 08 00:00:00 UTC 2022

Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.

Oncogene

Hao X,Bu W,Lv G,Xu L,Hou D,Wang J,Liu X,Yang T,Zhang X,Liu Q,Gong Y,Shao C

Sat Jan 01 00:00:00 UTC 2022

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.

Cell research

Hu CL,Chen BY,Li Z,Yang T,Xu CH,Yang R,Yu PC,Zhao J,Liu T,Liu N,Shan B,Zhang Q,Song J,Fei MY,Zong LJ,Zhang JY,Wu JC,Chen SB,Wang Y,Chang B,Hou D,Liu P,Jiang Y,Li X,Chen X,Deng CH,Ren YY,Wang R,Jin J,Xue K,Zhang Y,Du M,Shi J,Wu LY,Chang CK,Shen S,Chen Z,Chen SJ,Liu X,Sun XJ,Zheng M,Wang L

Thu Dec 01 00:00:00 UTC 2022

Solamargine Alleviated UVB-Induced Inflammation and Melanogenesis in Human Keratinocytes and Melanocytes via the p38 MAPK Signaling Pathway, a Promising Agent for Post-inflammatory Hyperpigmentation.

Frontiers in medicine

Zhao J,Dan Y,Liu Z,Wang Q,Jiang M,Zhang C,Sheu HM,Lin CS,Xiang L

Sat Jul 16 00:00:00 UTC 2022

SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.

Autophagy

Lee JE,Kim N,Jung M,Mun JY,Yoo JY

Fri Jul 01 00:00:00 UTC 2022

Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice.

Frontiers in cardiovascular medicine

Ren KW,Yu XH,Gu YH,Xie X,Wang Y,Wang SH,Li HH,Bi HL

Sat Oct 29 00:00:00 UTC 2022

Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.

Biochemical and biophysical research communications

Wang KX,Yan C,Yang X,Zhu PY,Cui WW,Ye C,Hu K,Lan T,Huang LY,Wang W,Ma P,Qi SH,Gu B,Luo L

Sat Jun 18 00:00:00 UTC 2022

LPS-Induced Activation of the cGAS-STING Pathway is Regulated by Mitochondrial Dysfunction and Mitochondrial DNA Leakage in Endometritis.

Journal of inflammation research

Li MZ,Wen XY,Liu XQ,Wang YQ,Yan L

Sat Oct 15 00:00:00 UTC 2022

lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization.

Research (Washington, D.C.)

Zhao K,Wang X,Zhao D,Lin Q,Zhang Y,Hu Y

Tue Aug 02 00:00:00 UTC 2022

Curcumae Radix Decreases Neurodegenerative Markers through Glycolysis Decrease and TCA Cycle Activation.

Nutrients

Jo SL,Yang H,Lee SR,Heo JH,Lee HW,Hong EJ

Mon Apr 11 00:00:00 UTC 2022

Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.

Viral immunology

Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z

Sat Oct 01 00:00:00 UTC 2022

S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.

Frontiers in oncology

Huang W,Zou L,Hao Z,Wang B,Mao F,Duan Q,Guo D

Sat Jul 16 00:00:00 UTC 2022

A long non-coding RNA as a direct vitamin D target transcribed from the antisense strand of the human HSD17B2 locus.

Bioscience reports

Kanemoto Y,Nishimura K,Hayakawa A,Sawada T,Amano R,Mori J,Kurokawa T,Murakami Y,Kato S

Fri May 27 00:00:00 UTC 2022

ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation.

Scientific reports

Azzarelli R,McNally A,Dell'Amico C,Onorati M,Simons B,Philpott A

Fri Feb 11 00:00:00 UTC 2022

Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.

International immunopharmacology

Chen X,Wu Q,Cao X,Yang Y,Gong Z,Ren T,Du Q,Yuan Y,Zuo Y,Miao Y,He J,Qiao C,Zheng Z,Zhang T,Xu Y,Wu D,Wang Q,Huang L,Xie Z,Lv H,Wang J,Gong F,Liu Z,Wen C,Zheng H

Tue Nov 01 00:00:00 UTC 2022

DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.

Cell death & disease

Wang YL,Zhao WW,Bai SM,Ma Y,Yin XK,Feng LL,Zeng GD,Wang F,Feng WX,Zheng J,Wang YN,Zeng B,Liu Q,Hung MC,Wan XB

Tue Aug 16 00:00:00 UTC 2022

cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.

Protein & cell

Li X,Li X,Xie C,Cai S,Li M,Jin H,Wu S,Cui J,Liu H,Zhao Y

Sat Jan 01 00:00:00 UTC 2022

Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway.

Scientific reports

Zhu W,Ding C,Huang P,Ran J,Lian P,Tang Y,Dai W,Huang X

Mon Apr 04 00:00:00 UTC 2022

HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.

British journal of cancer

Zhang G,Tan R,Wan S,Yang R,Hu X,Zhao E,Ding X,Zhang J,Li B,Liang P,Cui H

Tue Nov 01 00:00:00 UTC 2022

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine.

Frontiers in pharmacology

Huang PP,Zhu WQ,Xiao JM,Zhang YQ,Li R,Yang Y,Shen L,Luo F,Dai W,Lian PA,Tang YX,Ran JL,Huang XS

Tue Aug 30 00:00:00 UTC 2022

Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.

Frontiers in pharmacology

Gu YH,Ren KW,Wang Y,Wang SH,Yu XH,Xu LW,Li HH,Bi HL

Fri Nov 18 00:00:00 UTC 2022

An acetylated mannan isolated from Aloe vera induce colorectal cancer cells apoptosis via mitochondrial pathway.

Carbohydrate polymers

Tong X,Lao C,Li D,Du J,Chen J,Xu W,Li L,Ye H,Guo X,Li J

Thu Sep 01 00:00:00 UTC 2022

High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.

EMBO reports

Yuan Y,Miao Y,Ren T,Huang F,Qian L,Chen X,Zuo Y,Zhang HG,He J,Qiao C,Du Q,Wu Q,Zhang W,Zhu C,Xu Y,Wu D,Shi W,Jiang J,Xu G,Zheng H

Wed Jan 05 00:00:00 UTC 2022

Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes.

Frontiers in pharmacology

Lin Z,Li Z,Guo Z,Cao Y,Li J,Liu P,Li Z

Sat Jul 16 00:00:00 UTC 2022

Recycling of autophagosomal components from autolysosomes by the recycler complex.

Nature cell biology

Zhou C,Wu Z,Du W,Que H,Wang Y,Ouyang Q,Jian F,Yuan W,Zhao Y,Tian R,Li Y,Chen Y,Gao S,Wong CCL,Rong Y

Fri Apr 01 00:00:00 UTC 2022

Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model.

Redox biology

Pei Z,Qin Y,Fu X,Yang F,Huo F,Liang X,Wang S,Cui H,Lin P,Zhou G,Yan J,Wu J,Chen ZN,Zhu P

Tue Nov 01 00:00:00 UTC 2022

RAD51 is essential for spermatogenesis and male fertility in mice.

Cell death discovery

Qin J,Huang T,Wang J,Xu L,Dang Q,Xu X,Liu H,Liu Z,Shao C,Zhang X

Tue Mar 15 00:00:00 UTC 2022

LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.

Bioengineered

Sun Z,Xue C,Li J,Zhao H,Du Y,Du N

Tue Mar 01 00:00:00 UTC 2022

Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.

Oxidative medicine and cellular longevity

Chen P,Yang J,Wu N,Han B,Kastelic JP,Gao J

Fri Mar 18 00:00:00 UTC 2022

Maternal Factor Dppa3 Activates 2C-Like Genes and Depresses DNA Methylation in Mouse Embryonic Stem Cells.

Frontiers in cell and developmental biology

Zhang C,Wen H,Liu S,Fu E,Yu L,Chen S,Han Q,Li Z,Liu N

Sat Jul 16 00:00:00 UTC 2022

Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.

Cell reports

Liang C,Zhang S,Robinson D,Ploeg MV,Wilson R,Nah J,Taylor D,Beh S,Lim R,Sun L,Muoio DM,Stroud DA,Ho L

Tue Aug 16 00:00:00 UTC 2022

Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.

Pharmacological research

Sun X,Xiao H,Li S,Chen R,Lin Z,Yang Y,Chen Z,Deng L,Huang H

Tue Feb 01 00:00:00 UTC 2022

Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.

Functional & integrative genomics

Xiong Y,Song X,Zu X,Chen M,He W,Qi L

Sat Oct 01 00:00:00 UTC 2022

Inhibition of CK2 Reduces NG2 Expression in Juvenile Angiofibroma.

Biomedicines

Boewe AS,Wemmert S,Kulas P,Schick B,Götz C,Wrublewsky S,Montenarh M,Menger MD,Laschke MW,Ampofo E

Thu Apr 21 00:00:00 UTC 2022

Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation.

Nature communications

Xie Z,Hou L,Shen S,Wu Y,Wang J,Jie Z,Zhao X,Li X,Zhang X,Chen J,Xu W,Ning L,Ma Q,Wang S,Wang H,Yuan P,Fang X,Qin A,Fan S

Mon Jan 10 00:00:00 UTC 2022

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

Profile analysis and functional modeling identify circular RNAs in nonalcoholic fatty liver disease as regulators of hepatic lipid metabolism.

Frontiers in genetics

Xie Y,Cao Y,Guo CJ,Guo XY,He YF,Xu QY,Shen F,Pan Q

Tue Oct 04 00:00:00 UTC 2022

Hippocampal overexpression of TREM2 ameliorates high fat diet induced cognitive impairment and modulates phenotypic polarization of the microglia.

Genes & diseases

Wu M,Liao M,Huang R,Chen C,Tian T,Wang H,Li J,Li J,Sun Y,Wu C,Li Q,Xiao X

Tue Mar 01 00:00:00 UTC 2022

BRCC36 prevents vascular calcification in chronic kidney disease through the β-catenin signalling pathway.

Experimental cell research

Xie C,Chen C,Wu L,Xiong Y,Xing C,Mao H

Fri Apr 01 00:00:00 UTC 2022

Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.

Nature communications

Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW

Mon Nov 28 00:00:00 UTC 2022

Naringenin Promotes Myotube Formation and Maturation for Cultured Meat Production.

Foods (Basel, Switzerland)

Yan Q,Fei Z,Li M,Zhou J,Du G,Guan X

Tue Nov 22 00:00:00 UTC 2022

Circ_0004087 interaction with SND1 promotes docetaxel resistance in prostate cancer by boosting the mitosis error correction mechanism.

Journal of experimental & clinical cancer research : CR

Chen L,Song Y,Hou T,Li X,Cheng L,Li Y,Xing Y

Fri Jun 03 00:00:00 UTC 2022

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.

The EMBO journal

Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L

Thu Dec 01 00:00:00 UTC 2022

RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.

Science advances

Ma P,Wan LP,Li Y,He CH,Song NN,Zhao S,Wang H,Ding YQ,Mao B,Sheng N

Fri Sep 30 00:00:00 UTC 2022

Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.

Nature communications

Yuan K,Li Z,Kuang W,Wang X,Ji M,Chen W,Ding J,Li J,Min W,Sun C,Ye X,Lu M,Wang L,Ge H,Jiang Y,Hao H,Xiao Y,Yang P

Wed May 25 00:00:00 UTC 2022

Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.

Nature communications

Wang L,Wen X,Wang Z,Lin Z,Li C,Zhou H,Yu H,Li Y,Cheng Y,Chen Y,Lou G,Pan J,Cao M

Sat Jul 09 00:00:00 UTC 2022

Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.

Nature communications

Wang L,Wen X,Wang Z,Lin Z,Li C,Zhou H,Yu H,Li Y,Cheng Y,Chen Y,Lou G,Pan J,Cao M

Sat Jul 09 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Peripheral Transplantation of Mesenchymal Stem Cells at Sepsis Convalescence Improves Cognitive Function of Sepsis Surviving Mice.

Oxidative medicine and cellular longevity

Tan L,Cheng Y,Wang H,Tong J,Qin X

Wed Oct 05 00:00:00 UTC 2022

Camptothecin compromises transcription recovery and cell survival against cisplatin and ultraviolet irradiation regardless of transcription-coupled nucleotide excision repair.

DNA repair

Sakasai R,Wakasugi M,Matsui T,Sunatani Y,Saijo M,Matsunaga T,Iwabuchi K

Sun May 01 00:00:00 UTC 2022

Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway.

Cancer cell international

Li P,Li L,Li Z,Wang S,Li R,Zhao W,Feng Y,Huang S,Li L,Qiu H,Xia S

Thu Jan 06 00:00:00 UTC 2022

In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.

International journal of molecular sciences

Mareux E,Lapalus M,Ben Saad A,Zelli R,Lakli M,Riahi Y,Almes M,Banet M,Callebaut I,Decout JL,Falguières T,Jacquemin E,Gonzales E

Thu Sep 15 00:00:00 UTC 2022

In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.

International journal of molecular sciences

Mareux E,Lapalus M,Ben Saad A,Zelli R,Lakli M,Riahi Y,Almes M,Banet M,Callebaut I,Decout JL,Falguières T,Jacquemin E,Gonzales E

Thu Sep 15 00:00:00 UTC 2022

FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.

Cellular and molecular life sciences : CMLS

Zhou T,Chen T,Lai B,Zhang W,Luo X,Xia D,Fu W,Xu J

Mon May 02 00:00:00 UTC 2022

Hypotonic induction of aquaporin5 expression in rat astrocytes through p38 MAPK pathway.

Anatomia, histologia, embryologia

Yi Y,Qiu G,Liu H,Gao F,Liu X,Chen Y,Yang M

Tue Nov 01 00:00:00 UTC 2022

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells.

Journal of experimental & clinical cancer research : CR

Wu AC,Yang WB,Chang KY,Lee JS,Liou JP,Su RY,Cheng SM,Hwang DY,Kikkawa U,Hsu TI,Wang CY,Chang WC,Chen PY,Chuang JY

Wed Feb 02 00:00:00 UTC 2022

Cell cycle arrest induced by trichoplein depletion is independent of cilia assembly.

Journal of cellular physiology

Huang M,Kong X,Tang Z,Lin Z,He R,Cao M,Zhang X

Wed Jun 01 00:00:00 UTC 2022

Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome.

Nature genetics

Cousin MA,Creighton BA,Breau KA,Spillmann RC,Torti E,Dontu S,Tripathi S,Ajit D,Edwards RJ,Afriyie S,Bay JC,Harper KM,Beltran AA,Munoz LJ,Falcon Rodriguez L,Stankewich MC,Person RE,Si Y,Normand EA,Blevins A,May AS,Bier L,Aggarwal V,Mancini GMS,van Slegtenhorst MA,Cremer K,Becker J,Engels H,Aretz S,MacKenzie JJ,Brilstra E,van Gassen KLI,van Jaarsveld RH,Oegema R,Parsons GM,Mark P,Helbig I,McKeown SE,Stratton R,Cogne B,Isidor B,Cacheiro P,Smedley D,Firth HV,Bierhals T,Kloth K,Weiss D,Fairley C,Shieh JT,Kritzer A,Jayakar P,Kurtz-Nelson E,Bernier RA,Wang T,Eichler EE,van de Laar IMBH,McConkie-Rosell A,McDonald MT,Kemppainen J,Lanpher BC,Schultz-Rogers LE,Gunderson LB,Pichurin PN,Yoon G,Zech M,Jech R,Winkelmann J,Beltran AS,Zimmermann MT,Temple B,Moy SS,Klee EW,Tan QK,Lorenzo DN

Thu Jul 01 00:00:00 UTC 2021

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.

Neuron

Wang C,Xiong M,Gratuze M,Bao X,Shi Y,Andhey PS,Manis M,Schroeder C,Yin Z,Madore C,Butovsky O,Artyomov M,Ulrich JD,Holtzman DM

Wed May 19 00:00:00 UTC 2021

Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases.

Proceedings of the National Academy of Sciences of the United States of America

De Cesare V,Carbajo Lopez D,Mabbitt PD,Fletcher AJ,Soetens M,Antico O,Wood NT,Virdee S

Tue Jan 26 00:00:00 UTC 2021

NR1D1 Deletion Induces Rupture-Prone Vulnerable Plaques by Regulating Macrophage Pyroptosis via the NF-κB/NLRP3 Inflammasome Pathway.

Oxidative medicine and cellular longevity

Wu Z,Liao F,Luo G,Qian Y,He X,Xu W,Ding S,Pu J

Thu Mar 03 00:00:00 UTC 2022

NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.

Oxidative medicine and cellular longevity

Su X,Yang Y,Guo C,Zhang R,Sun S,Wang Y,Qiao Q,Fu Y,Pang Q

Wed Jan 05 00:00:00 UTC 2022

Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor.

Development (Cambridge, England)

Otsu K,Ida-Yonemochi H,Ikezaki S,Ema M,Hitomi J,Ohshima H,Harada H

Mon Feb 15 00:00:00 UTC 2021

Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.

International journal of molecular sciences

Chen F,Jiao XF,Meng F,Wang YS,Ding ZM,Miao YL,Xiong JJ,Huo LJ

Mon May 03 00:00:00 UTC 2021

Pinocembrin relieves lipopolysaccharide and bleomycin induced lung inflammation via inhibiting TLR4-NF-κB-NLRP3 inflammasome signaling pathway.

International immunopharmacology

Gan W,Li X,Cui Y,Xiao T,Liu R,Wang M,Wei Y,Cui M,Ren S,Helian K,Ning W,Zhou H,Yang C

Fri Jan 01 00:00:00 UTC 2021

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.

Cell metabolism

Liu Y,Liang G,Xu H,Dong W,Dong Z,Qiu Z,Zhang Z,Li F,Huang Y,Li Y,Wu J,Yin S,Zhang Y,Guo P,Liu J,Xi JJ,Jiang P,Han D,Yang CG,Xu MM

Tue Jun 01 00:00:00 UTC 2021

OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.

Pathology, research and practice

Ge X,Peng X,Li M,Ji F,Chen J,Zhang D

Wed Sep 01 00:00:00 UTC 2021

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.

International journal of molecular sciences

Zhou H,Su H,Chen W

Wed Sep 01 00:00:00 UTC 2021

Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.

eLife

Wang D,Ye Z,Wei W,Yu J,Huang L,Zhang H,Yue J

Fri Nov 19 00:00:00 UTC 2021

Nitrogen-Doped Multiwalled Carbon Nanotubes Enhance Bone Remodeling through Immunomodulatory Functions.

ACS applied materials & interfaces

Li H,He D,Xiao X,Yu G,Hu G,Zhang W,Wen X,Lin Y,Li X,Lin H,Diao Y,Tang Y

Wed Jun 02 00:00:00 UTC 2021

CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.

Cancers

Schmitt BM,Boewe AS,Götz C,Philipp SE,Urbschat S,Oertel J,Menger MD,Laschke MW,Ampofo E

Fri Apr 02 00:00:00 UTC 2021

Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.

Research in veterinary science

Xing Y,Wang L,Xu G,Guo S,Zhang M,Cheng G,Liu Y,Liu J

Mon Nov 01 00:00:00 UTC 2021

Loss of E-cadherin due to road dust PM_2.5 activates the EGFR in human pharyngeal epithelial cells.

Environmental science and pollution research international

Tung NT,Ho KF,Niu X,Sun J,Shen Z,Wu F,Cao J,Dung HB,Thuy TPC,Hsiao TC,Liu WT,Chuang HC

Fri Oct 01 00:00:00 UTC 2021

Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress.

Cell proliferation

Wu L,He S,Ye W,Shen J,Zhao K,Zhang Y,Zhang R,Wei J,Cao S,Chen K,Le R,Xi C,Kou X,Zhao Y,Wang H,Kang L,Gao S

Mon Nov 01 00:00:00 UTC 2021

Gut Metabolite Trimethylamine N-Oxide Protects INS-1 β-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions.

Biomolecules

Krueger ES,Beales JL,Russon KB,Elison WS,Davis JR,Hansen JM,Neilson AP,Hansen JM,Tessem JS

Fri Dec 17 00:00:00 UTC 2021

Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.

JCI insight

Xu G,Fu S,Zhan X,Wang Z,Zhang P,Shi W,Qin N,Chen Y,Wang C,Niu M,Guo Y,Wang J,Bai Z,Xiao X

Mon Jan 25 00:00:00 UTC 2021

RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense.

Cell death and differentiation

Guo X,Ma P,Li Y,Yang Y,Wang C,Xu T,Wang H,Li C,Mao B,Qi X

Mon Feb 01 00:00:00 UTC 2021

Nuclear Lamin A/C Expression Is a Key Determinant of Paclitaxel Sensitivity.

Molecular and cellular biology

Smith ER,Leal J,Amaya C,Li B,Xu XX

Wed Jun 23 00:00:00 UTC 2021

Proteomic analysis of the exosomes secreted from Ctenopharyngodon idellus kidney cells infected with grass carp reovirus reveals their involvement in the cellular responses to viral infection.

Fish physiology and biochemistry

Zhang X,Zhang Y,Pan J,Zhu M,Liang Z,Shen Z,Dai K,Yan B,Dai Y,Xue R,Cao G,Hu X,Gong C

Sun Aug 01 00:00:00 UTC 2021

Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer.

Cancer immunology, immunotherapy : CII

Liu Y,Huang Z,Wei Y,Zhang M,Li X,Yang S,Wang H

Mon Feb 01 00:00:00 UTC 2021

ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.

Cell death & disease

Zhang W,Zhang R,Zeng Y,Li Y,Chen Y,Zhou J,Zhang Y,Wang A,Zhu J,Liu Z,Yan Z,Huang JA

Sat Jul 31 00:00:00 UTC 2021

Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.

Biochemical pharmacology

Wu H,Chen Y,Li B,Li C,Guo J,You J,Hu X,Kuang D,Qi S,Liu P,Li L,Xu C

Mon Feb 01 00:00:00 UTC 2021

PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca²⁺/Calpain/VE-Cadherin Signaling.

Frontiers in molecular biosciences

Guo XW,Zhang H,Huang JQ,Wang SN,Lu Y,Cheng B,Dong SH,Wang YY,Li FS,Li YW

Wed Sep 29 00:00:00 UTC 2021

Ginsenoside Rb1 protected PC12 cells from Aβ_25-35-induced cytotoxicity via PPARγ activation and cholesterol reduction.

European journal of pharmacology

Changhong K,Peng Y,Yuan Z,Cai J

Mon Feb 15 00:00:00 UTC 2021

Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.

Redox biology

Du L,Xie Y,Zheng K,Wang N,Gao M,Yu T,Cao L,Shao Q,Zou Y,Xia W,Fang Q,Zhao B,Guo D,Peng X,Pan JA

Fri Nov 26 00:00:00 UTC 2021

Regulation of PDGFR-β gene expression by targeting the G-vacancy bearing G-quadruplex in promoter.

Nucleic acids research

Chen JN,He YD,Liang HT,Cai TT,Chen Q,Zheng KW

Thu Dec 16 00:00:00 UTC 2021

Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK1.

Molecular therapy. Nucleic acids

Zhu M,Liang Z,Pan J,Zhang X,Xue R,Cao G,Hu X,Gong C

Fri Sep 03 00:00:00 UTC 2021

Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer.

Frontiers in oncology

Lin Z,Li Q,Zhao Y,Lin Z,Cheng N,Zhang D,Liu G,Lin J,Zhang H,Lin D

Wed Dec 15 00:00:00 UTC 2021

Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.

Cancer gene therapy

Liu Y,Wang Y,Liu J,Kang R,Tang D

Mon Feb 01 00:00:00 UTC 2021

FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.

Frontiers in cardiovascular medicine

Zhuang L,Mao Y,Liu Z,Li C,Jin Q,Lu L,Tao R,Yan X,Chen K

Tue Aug 31 00:00:00 UTC 2021

Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.

The EMBO journal

Xu Y,Shi T,Cui X,Yan L,Wang Q,Xu X,Zhao Q,Xu X,Tang QQ,Tang H,Pan D

Wed Dec 15 00:00:00 UTC 2021

BCL7C suppresses ovarian cancer growth by inactivating mutant p53.

Journal of molecular cell biology

Huang C,Hao Q,Shi G,Zhou X,Zhang Y

Fri May 07 00:00:00 UTC 2021

Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose-induced senescence and apoptosis.

Experimental and therapeutic medicine

Hong H,Xiao J,Guo Q,Du J,Jiang Z,Lu S,Zhang H,Zhang X,Wang X

Mon Nov 01 00:00:00 UTC 2021

A newly identified small molecular compound acts as a protein kinase inhibitor to suppress metastasis of colorectal cancer.

Bioorganic chemistry

Qi L,Zhang Y,Song F,Han Y,Ding Y

Mon Feb 01 00:00:00 UTC 2021

Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants.

Liver international : official journal of the International Association for the Study of the Liver

Ben Saad A,Vauthier V,Tóth Á,Janaszkiewicz A,Durand-Schneider AM,Bruneau A,Delaunay JL,Lapalus M,Mareux E,Garcin I,Gonzales E,Housset C,Aït-Slimane T,Jacquemin E,Di Meo F,Falguières T

Tue Jun 01 00:00:00 UTC 2021

NLRP3 inflammasome of renal tubular epithelial cells induces kidney injury in acute hemolytic transfusion reactions.

Clinical and translational medicine

Liu Z,Chen Y,Niu B,Yin D,Feng F,Gu S,An Q,Xu J,An N,Zhang J,Yi J,Yin W,Qin X,Hu X

Mon Mar 01 00:00:00 UTC 2021

EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.

Journal of neuroinflammation

Liu T,Li T,Chen X,Li Z,Feng M,Yao W,Wan L,Zhang C,Zhang Y

Thu Sep 16 00:00:00 UTC 2021

Enterovirus D68 Protease 2A^pro Targets TRAF3 To Subvert Host Innate Immune Responses.

Journal of virology

Kang J,Pang Z,Zhou Z,Li X,Liu S,Cheng J,Liu P,Tan W,Wang Z,Wang T

Wed Jan 13 00:00:00 UTC 2021

Triple-Negative Breast Cancer Cells Recruit Neutrophils by Secreting TGF-β and CXCR2 Ligands.

Frontiers in immunology

SenGupta S,Hein LE,Xu Y,Zhang J,Konwerski JR,Li Y,Johnson C,Cai D,Smith JL,Parent CA

Mon Oct 18 00:00:00 UTC 2021

USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.

Biochemical pharmacology

Sun XH,Xiao HM,Zhang M,Lin ZY,Yang Y,Chen R,Liu PQ,Huang KP,Huang HQ

Tue Jun 01 00:00:00 UTC 2021

MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway.

EBioMedicine

Ling Q,Li F,Zhang X,Mao S,Lin X,Pan J,Ye W,Wei W,Qian Y,Hu C,Huang X,Wang J,Wang H,Huang J,Wang Y,Jin J

Thu Jul 01 00:00:00 UTC 2021

lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.

Molecular therapy. Nucleic acids

Li D,Wang X,Dang Y,Zhang X,Zhao S,Lu G,Chan WY,Leung PCK,Qin Y

Fri Mar 05 00:00:00 UTC 2021

Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Hao W,Hao C,Wu C,Xu Y,Wu S,Lu X,Yang J,Jin C

Mon Nov 01 00:00:00 UTC 2021

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.

Life science alliance

Redl E,Sheibani-Tezerji R,Cardona CJ,Hamminger P,Timelthaler G,Hassler MR,Zrimšek M,Lagger S,Dillinger T,Hofbauer L,Draganić K,Tiefenbacher A,Kothmayer M,Dietz CH,Ramsahoye BH,Kenner L,Bock C,Seiser C,Ellmeier W,Schweikert G,Egger G

Mon Feb 01 00:00:00 UTC 2021

UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

Molecular oncology

Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y

Wed Dec 01 00:00:00 UTC 2021

UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

Molecular oncology

Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y

Wed Dec 01 00:00:00 UTC 2021

Effects of detraining on preconditioning exercise-induced neuroprotective potential after ischemic stroke in rats.

Brain structure & function

Otsuka S,Sakakima H,Tani A,Nakanishi K,Takada S,Norimatsu K,Maejima H,Maruyama I

Wed Sep 01 00:00:00 UTC 2021

Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.

Journal of Cancer

Chen L,Yi C,Li W,Tseng Y,Zhang J,Liu J

Tue Jan 05 00:00:00 UTC 2021

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.

iScience

Zhang X,Wang Z,Xu Q,Chen Y,Liu W,Zhong T,Li H,Quan C,Zhang L,Cui CP

Fri Oct 22 00:00:00 UTC 2021

PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Yan L,Jin W,Zhao Q,Cui X,Shi T,Xu Y,Li F,Jin W,Zhang Z,Zhang Z,Tang QQ,Pan D

Sun Aug 01 00:00:00 UTC 2021

Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.

Molecular cancer research : MCR

Wang Q,Wu H,Hu J,Fu H,Qu Y,Yang Y,Cai KQ,Efimov A,Wu M,Yen T,Wang Y,Yang ZJ

Fri Oct 01 00:00:00 UTC 2021

Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.

Molecular cancer research : MCR

Wang Q,Wu H,Hu J,Fu H,Qu Y,Yang Y,Cai KQ,Efimov A,Wu M,Yen T,Wang Y,Yang ZJ

Fri Oct 01 00:00:00 UTC 2021

ATG5 is instrumental in the transition from autophagy to apoptosis during the degeneration of tick salivary glands.

PLoS neglected tropical diseases

Wang Y,Zhang H,Luo L,Zhou Y,Cao J,Xuan X,Suzuki H,Zhou J

Fri Jan 01 00:00:00 UTC 2021

Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.

Biochemical and biophysical research communications

Cai Y,Gu WT,Cheng K,Jia PF,Li F,Wang M,Zhang WF,Qiu JT,Wu ZB,Zhao WG

Fri Apr 23 00:00:00 UTC 2021

ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.

Cellular signalling

Cao C,He K,Li S,Ge Q,Liu L,Zhang Z,Zhang H,Wang X,Sun X,Ding L

Wed Sep 01 00:00:00 UTC 2021

Methylation of dual-specificity phosphatase 4 controls cell differentiation.

Cell reports

Su H,Jiang M,Senevirathne C,Aluri S,Zhang T,Guo H,Xavier-Ferrucio J,Jin S,Tran NT,Liu SM,Sun CW,Zhu Y,Zhao Q,Chen Y,Cable L,Shen Y,Liu J,Qu CK,Han X,Klug CA,Bhatia R,Chen Y,Nimer SD,Zheng YG,Iancu-Rubin C,Jin J,Deng H,Krause DS,Xiang J,Verma A,Luo M,Zhao X

Tue Jul 27 00:00:00 UTC 2021

p53 induces ARTS to promote mitochondrial apoptosis.

Cell death & disease

Hao Q,Chen J,Liao J,Huang Y,Gan Y,Larisch S,Zeng SX,Lu H,Zhou X

Wed Feb 24 00:00:00 UTC 2021

CircSTK40 contributes to recurrent implantation failure via modulating the HSP90/AKT/FOXO1 axis.

Molecular therapy. Nucleic acids

Ni T,Zhang Q,Li Y,Huang C,Zhou T,Yan J,Chen ZJ

Fri Dec 03 00:00:00 UTC 2021

Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC).

OncoTargets and therapy

Huang GZ,Wu QQ,Zheng ZN,Shao TR,Li F,Lu XY,Ye HY,Chen GX,Song YX,Zeng WS,Ai YL,Lv XZ

Thu Apr 21 00:00:00 UTC 2022

Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.

Journal of virology

Luo MT,Mu D,Yang X,Luo RH,Zheng HY,Chen M,Guo YQ,Zheng YT

Mon Jul 26 00:00:00 UTC 2021

Hypoxia regulates overall mRNA homeostasis by inducing Met¹-linked linear ubiquitination of AGO2 in cancer cells.

Nature communications

Zhang H,Zhao X,Guo Y,Chen R,He J,Li L,Qiang Z,Yang Q,Liu X,Huang C,Lu R,Fang J,Cao Y,Huang J,Wang Y,Huang J,Chen GQ,Cheng J,Yu J

Mon Sep 13 00:00:00 UTC 2021

Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.

Life science alliance

Ibe NU,Subramanian A,Mukherjee S

Wed Dec 01 00:00:00 UTC 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.

eLife

Gautheron J,Morisseau C,Chung WK,Zammouri J,Auclair M,Baujat G,Capel E,Moulin C,Wang Y,Yang J,Hammock BD,Cerame B,Phan F,Fève B,Vigouroux C,Andreelli F,Jeru I

Tue Aug 03 00:00:00 UTC 2021

EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development.

Investigative ophthalmology & visual science

Cao X,An J,Cao Y,Lv J,Wang J,Ding Y,Lin X,Zhou X

Mon Feb 01 00:00:00 UTC 2021

Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.

Frontiers in pharmacology

Han Y,Jiang M,He R,Lv X,Liao X,He Y,Zhang F,Long L,Jiang G,Peng Z,Tao L,Hu G,Meng J

Tue Oct 12 00:00:00 UTC 2021

Discovery of a novel AR/HDAC6 dual inhibitor for prostate cancer treatment.

Aging

Zhou M,Zheng H,Li Y,Huang H,Min X,Dai S,Zhou W,Chen Z,Xu G,Chen Y

Wed Feb 17 00:00:00 UTC 2021

Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis.

Molecular neurobiology

Otsuka S,Setoyama K,Takada S,Nakanishi K,Terashi T,Norimatsu K,Tani A,Sakakima H,Maruyama I,Tancharoen S,Tanaka E,Kikuchi K

Mon Nov 01 00:00:00 UTC 2021

NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia.

Science advances

Srivastava S,Sahu U,Zhou Y,Hogan AK,Sathyan KM,Bodner J,Huang J,Wong KA,Khalatyan N,Savas JN,Ntziachristos P,Ben-Sahra I,Foltz DR

Fri Jan 01 00:00:00 UTC 2021

Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling.

Frontiers in cell and developmental biology

Bernatik O,Paclikova P,Kotrbova A,Bryja V,Cajanek L

Tue Mar 16 00:00:00 UTC 2021

GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.

Molecular medicine reports

Li SS,Chen DM,Chen LB,Wei H,Wang JL,Xiao J,Huang YH,Lian YF

Tue Jun 01 00:00:00 UTC 2021

Identification of the Bcl-2 and Bax homologs from Rhipicephalus haemaphysaloides and their function in the degeneration of tick salivary glands.

Parasites & vectors

Hu S,Wang Y,Xu Z,Zhou Y,Cao J,Zhang H,Zhou J

Wed Aug 04 00:00:00 UTC 2021

Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150^glued.

Molecular brain

Suh BK,Lee SA,Park C,Suh Y,Kim SJ,Woo Y,Nhung TTM,Lee SB,Mun DJ,Goo BS,Choi HS,Kim SJ,Park SK

Mon Jan 18 00:00:00 UTC 2021

Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.

PloS one

Anchoori RK,George L,Tseng SH,Lam B,Polkampally S,Amiano AD,Foran P,Tsingine H,Samanapally H,Carrizo Velasquez F,Das S,Xing D,Bin Salam A,Karanam B,Hung CF,Roden RBS

Thu Nov 18 00:00:00 UTC 2021

Identification of proximal SUMO-dependent interactors using SUMO-ID.

Nature communications

Barroso-Gomila O,Trulsson F,Muratore V,Canosa I,Merino-Cacho L,Cortazar AR,Pérez C,Azkargorta M,Iloro I,Carracedo A,Aransay AM,Elortza F,Mayor U,Vertegaal ACO,Barrio R,Sutherland JD

Thu Nov 18 00:00:00 UTC 2021

TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.

Cell death and differentiation

Nie X,Xiao D,Ge Y,Xie Y,Zhou H,Zheng T,Li X,Liu H,Huang H,Zhao Y

Mon Mar 01 00:00:00 UTC 2021

LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.

Redox biology

Wei WS,Wang N,Deng MH,Dong P,Liu JY,Xiang Z,Li XD,Li ZY,Liu ZH,Peng YL,Li Z,Jiang LJ,Yao K,Ye YL,Lu WH,Zhang ZL,Zhou FJ,Liu ZW,Xie D,Yu CP

Sat Nov 27 00:00:00 UTC 2021

SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.

Nature communications

Shangguan X,He J,Ma Z,Zhang W,Ji Y,Shen K,Yue Z,Li W,Xin Z,Zheng Q,Cao Y,Pan J,Dong B,Cheng J,Wang Q,Xue W

Mon Mar 22 00:00:00 UTC 2021

Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3.

Autophagy

Wen W,Li X,Yin M,Wang H,Qin L,Li H,Liu W,Zhao Z,Zhao Q,Chen H,Hu J,Qian P

Mon Nov 01 00:00:00 UTC 2021

Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.

Frontiers in veterinary science

Lin Z,Lin Z,Zhao Y,Cheng N,Zhang D,Lin J,Zhang H,Lin D

Tue Jan 04 00:00:00 UTC 2022

One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver.

International journal of molecular sciences

Sugasawa T,Ono S,Yonamine M,Fujita SI,Matsumoto Y,Aoki K,Nakano T,Tamai S,Yoshida Y,Kawakami Y,Takekoshi K

Sat May 29 00:00:00 UTC 2021

HOIL-1-catalysed, ester-linked ubiquitylation restricts IL-18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages.

The FEBS journal

Petrova T,Zhang J,Nanda SK,Figueras-Vadillo C,Cohen P

Fri Oct 01 00:00:00 UTC 2021

N6-methyladenosine regulates ATM expression and downstream signaling.

Journal of Cancer

Zhang X,Liu P,Zheng X,Wang J,Peng Q,Li Z,Wei L,Liu C,Wu Y,Wen Y,Yan Q,Ma J

Sat Aug 17 00:00:00 UTC 2024

Antibody Self-Assembly Maximizes Cytoplasmic Immunostaining Accuracy of Compact Quantum Dots.

Chemistry of materials : a publication of the American Chemical Society

Ma L,Geng J,Kolossov VL,Han Z,Pei Y,Lim SJ,Kilian KA,Smith AM

Tue Jul 13 00:00:00 UTC 2021

Screening and identification of autophagy-related biomarkers for oral squamous cell carcinoma (OSCC) via integrated bioinformatics analysis.

Journal of cellular and molecular medicine

Huang GZ,Lu ZY,Rao Y,Gao H,Lv XZ

Sat May 01 00:00:00 UTC 2021

FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation.

Cell death & disease

Liu X,Ge J,Chen C,Shen Y,Xie J,Zhu X,Liu M,Hu J,Chen L,Guo L,Zhou Q,Yan X,Qiu Y,Wan R,Marian AJ,Hong K

Tue Jan 05 00:00:00 UTC 2021

Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway.

Journal of immunology research

Lin Y,Xie Y,Hao Z,Bi H,Liu Y,Yang X,Xia Y

Thu Mar 03 00:00:00 UTC 2022

Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.

Journal of immunology (Baltimore, Md. : 1950)

Wen W,Li X,Wang H,Zhao Q,Yin M,Liu W,Chen H,Qian P

Thu Jul 01 00:00:00 UTC 2021

In vitro and in vivo synergistic anti-tumor effect of LIN28 inhibitor and metformin in oral squamous cell carcinoma.

European journal of pharmacology

Chen H,Sa G,Li L,He S,Wu T

Fri Jan 15 00:00:00 UTC 2021

Disrupted-in-schizophrenia 1 enhances the quality of circadian rhythm by stabilizing BMAL1.

Translational psychiatry

Lee SB,Park J,Kwak Y,Park YU,Nhung TTM,Suh BK,Woo Y,Suh Y,Cho E,Cho S,Park SK

Thu Feb 04 00:00:00 UTC 2021

Comprehensive Analysis of the Expression and Prognosis Value of Chromobox Family Members in Clear Cell Renal Cell Carcinoma.

Frontiers in oncology

Zhu Y,Pu Z,Li Z,Lin Y,Li N,Peng F

Tue Aug 17 00:00:00 UTC 2021

Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANA^SIM-Associated Proteins in Hypoxia.

mSystems

Liu X,Gan J,Du S,Zhu C,Wang Y,Jia Y,Zhang D,Qu D,Wei F,Robertson ES,Cai Q

Tue Dec 21 00:00:00 UTC 2021

Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANA^SIM-Associated Proteins in Hypoxia.

mSystems

Liu X,Gan J,Du S,Zhu C,Wang Y,Jia Y,Zhang D,Qu D,Wei F,Robertson ES,Cai Q

Tue Dec 21 00:00:00 UTC 2021

Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment.

The Journal of biological chemistry

McKinzey DR,Gomathinayagam S,Griffin WC,Klinzing KN,Jeffries EP,Rajkovic A,Trakselis MA

Tue Aug 24 00:00:00 UTC 2021

Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.

Microorganisms

Chen S,Li Y,Chu B,Yuan L,Liu N,Zhu Y,Wang J

Fri Sep 17 00:00:00 UTC 2021

Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells.

Bioactive materials

Zhang Y,Elechalawar CK,Hossen MN,Francek ER,Dey A,Wilhelm S,Bhattacharya R,Mukherjee P

Mon Feb 01 00:00:00 UTC 2021

Melatonin Alleviates Renal Injury in Mouse Model of Sepsis.

Frontiers in pharmacology

Chen L,Han Z,Shi Z,Liu C,Lu Q

Tue Sep 21 00:00:00 UTC 2021

Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.

Frontiers in cardiovascular medicine

Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y

Tue Jan 11 00:00:00 UTC 2022

Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.

Frontiers in cardiovascular medicine

Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y

Tue Jan 11 00:00:00 UTC 2022

Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.

Frontiers in cardiovascular medicine

Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y

Tue Jan 11 00:00:00 UTC 2022

Small Molecule Palmatine Targeting Musashi-2 in Colorectal Cancer.

Frontiers in pharmacology

Zhang X,Su K,Liu Y,Zhu D,Pan Y,Ke X,Qu Y

Wed Feb 16 00:00:00 UTC 2022

RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic.

International journal of molecular sciences

Ben Saad A,Vauthier V,Lapalus M,Mareux E,Bennana E,Durand-Schneider AM,Bruneau A,Delaunay JL,Gonzales E,Housset C,Aït-Slimane T,Guillonneau F,Jacquemin E,Falguières T

Wed Jun 30 00:00:00 UTC 2021

The translational repressor 4E-BP1 regulates RRM2 levels and functions as a tumor suppressor in Ewing sarcoma tumors.

Oncogene

Goss KL,Koppenhafer SL,Waters T,Terry WW,Wen KK,Wu M,Ostergaard J,Gordon PM,Gordon DJ

Fri Jan 01 00:00:00 UTC 2021

Cadmium exposure induces osteoporosis through cellular senescence, associated with activation of NF-κB pathway and mitochondrial dysfunction.

Environmental pollution (Barking, Essex : 1987)

Luo H,Gu R,Ouyang H,Wang L,Shi S,Ji Y,Bao B,Liao G,Xu B

Wed Dec 01 00:00:00 UTC 2021

Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.

Journal of neuroinflammation

Wang M,Feng LR,Li ZL,Ma KG,Chang KW,Chen XL,Yang PB,Ji SF,Ma YB,Han H,Ruganzua JB,Yang WN,Qian YH

Mon Jun 28 00:00:00 UTC 2021

Olanzapine leads to nonalcoholic fatty liver disease through the apolipoprotein A5 pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Li R,Zhu W,Huang P,Yang Y,Luo F,Dai W,Shen L,Pei W,Huang X

Wed Sep 01 00:00:00 UTC 2021

CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.

Pharmacological research

Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H

Fri Jan 01 00:00:00 UTC 2021

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.

iScience

Zou Q,Yang L,Shi R,Qi Y,Zhang X,Qi H

Fri Dec 17 00:00:00 UTC 2021

Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer.

FEBS open bio

Yang Z,Sun H,Ma W,Wu K,Peng G,Ou T,Wu S

Wed Sep 01 00:00:00 UTC 2021

The transcription factor NF-Y participates to stem cell fate decision and regeneration in adult skeletal muscle.

Nature communications

Rigillo G,Basile V,Belluti S,Ronzio M,Sauta E,Ciarrocchi A,Latella L,Saclier M,Molinari S,Vallarola A,Messina G,Mantovani R,Dolfini D,Imbriano C

Thu Oct 14 00:00:00 UTC 2021

Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway.

Frontiers in pharmacology

Lv X,Yao T,He R,He Y,Li M,Han Y,Zhang Y,Long L,Jiang G,Cheng X,Xie Y,Huang L,Peng Z,Hu G,Li Q,Tao L,Meng J

Fri Jan 07 00:00:00 UTC 2022

Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients.

Journal of experimental & clinical cancer research : CR

Belluti S,Semeghini V,Rigillo G,Ronzio M,Benati D,Torricelli F,Reggiani Bonetti L,Carnevale G,Grisendi G,Ciarrocchi A,Dominici M,Recchia A,Dolfini D,Imbriano C

Mon Nov 15 00:00:00 UTC 2021

Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.

Journal of agricultural and food chemistry

Zhang Q,Su G,Yang Q,Wei Z,Wang J,Zheng L,Zhao M

Wed Sep 15 00:00:00 UTC 2021

Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9⁺ cells to prevent the development of liver cancer in a mouse model.

Stem cell research & therapy

Chen M,Lu C,Lu H,Zhang J,Qin D,Liu S,Li X,Zhang L

Mon Apr 12 00:00:00 UTC 2021

Caspase-3/NLRP3 signaling in the mesenchymal stromal niche regulates myeloid-biased hematopoiesis.

Stem cell research & therapy

Zhang J,Chen Y,Yin D,Feng F,An Q,Liu Z,An N,Xu J,Yi J,Gu S,Yin W,Wang Y,Hu X

Sat Nov 20 00:00:00 UTC 2021

Sirt3 Maintains Microvascular Endothelial Adherens Junction Integrity to Alleviate Sepsis-Induced Lung Inflammation by Modulating the Interaction of VE-Cadherin and β-Catenin.

Oxidative medicine and cellular longevity

Chen DQ,Shen MJ,Wang H,Li Y,Tang AL,Li S,Xiong MC,Guo Y,Zhang GQ

Fri Feb 04 00:00:00 UTC 2022

MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.

Development (Cambridge, England)

Wang X,Wen Y,Zhang J,Swanson G,Guo S,Cao C,Krawetz SA,Zhang Z,Yuan S

Thu Apr 01 00:00:00 UTC 2021

Embryonic stem cell-derived extracellular vesicles promote the recovery of kidney injury.

Stem cell research & therapy

Yu L,Liu S,Wang C,Zhang C,Wen Y,Zhang K,Chen S,Huang H,Liu Y,Wu L,Han Z,Chen X,Li Z,Liu N

Fri Jul 02 00:00:00 UTC 2021

Effect of low-intensity motor balance and coordination exercise on cognitive functions, hippocampal Aβ deposition, neuronal loss, neuroinflammation, and oxidative stress in a mouse model of Alzheimer's disease.

Experimental neurology

Nakanishi K,Sakakima H,Norimatsu K,Otsuka S,Takada S,Tani A,Kikuchi K

Mon Mar 01 00:00:00 UTC 2021

Cholesterol-25-Hydroxylase Suppresses Seneca Valley Virus Infection via Producing 25-Hydroxycholesterol to Block Adsorption Procedure.

Virologica Sinica

Li H,Zhao Z,Li X,Qin L,Wen W,Chen H,Qian P

Fri Oct 01 00:00:00 UTC 2021

FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation.

Cell death & disease

Xu L,Xu W,Li D,Yu X,Gao F,Qin Y,Yang Y,Zhao S

Mon Aug 09 00:00:00 UTC 2021

Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy.

Aging

Shen Z,Ji K,Cai Z,Huang C,He X,Xu H,Chen G

Fri Mar 19 00:00:00 UTC 2021

CUL4^high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival.

The American journal of pathology

Wang Y,Yan F,Nasar A,Chen ZS,Altorki NK,Stiles B,Narula N,Zhou P

Wed Sep 01 00:00:00 UTC 2021

Snail enhances arginine synthesis by inhibiting ubiquitination-mediated degradation of ASS1.

EMBO reports

Jia H,Yang Y,Li M,Chu Y,Song H,Zhang J,Zhang D,Zhang Q,Xu Y,Wang J,Xu H,Zou X,Peng H,Hou Z

Wed Aug 04 00:00:00 UTC 2021

BRCC36 functions noncatalytically to promote antiviral response by maintaining STAT1 protein stability.

European journal of immunology

Cheng Q,Feng Q,Xu Y,Zuo Y,Liu J,Yuan Y,Miao Y,Liu Y,Lei L,Guo T,Zhang L,Wu D,Zheng H

Mon Feb 01 00:00:00 UTC 2021

Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3.

Immunology

Chen X,Xu Y,Tu W,Huang F,Zuo Y,Zhang HG,Jin L,Feng Q,Ren T,He J,Miao Y,Yuan Y,Zhao Q,Liu J,Zhang R,Zhu L,Qian F,Zhu C,Zheng H,Wang J

Thu Jul 01 00:00:00 UTC 2021

HSV-1-encoded ICP0 degrades the host deubiquitinase BRCC36 to antagonize interferon antiviral response.

Molecular immunology

Zhang L,Huang F,Liu J,Xu Y,Miao Y,Yuan Y,Chen X,Zhang HG,Wang J,Zheng H,Zuo Y

Thu Jul 01 00:00:00 UTC 2021

Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.

Theranostics

Guo S,Meng L,Liu H,Yuan L,Zhao N,Ni J,Zhang Y,Ben J,Li YP,Ma J

Thu Jul 29 00:00:00 UTC 2021

Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.

Cell death discovery

Ge W,Wang Y,Zheng S,Zhao D,Wang X,Zhang X,Hu Y

Mon Jul 26 00:00:00 UTC 2021

SIRT2 ablation inhibits glucose-stimulated insulin secretion through decreasing glycolytic flux.

Theranostics

Zhou F,Zhang L,Zhu K,Bai M,Zhang Y,Zhu Q,Wang S,Sheng C,Yuan M,Liu Y,Lu J,Shao L,Wang X,Zhou L

Mon Aug 16 00:00:00 UTC 2021

Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.

Bioorganic chemistry

Liang Y,Zhang M,Zhou P,Liu M,Li J,Wang Y

Fri Oct 01 00:00:00 UTC 2021

Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.

Journal of experimental & clinical cancer research : CR

Liu S,Chen L,Chen H,Xu K,Peng X,Zhang M

Fri Feb 12 00:00:00 UTC 2021

Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells.

Cell death & disease

Yang WB,Wu AC,Hsu TI,Liou JP,Lo WL,Chang KY,Chen PY,Kikkawa U,Yang ST,Kao TJ,Chen RM,Chang WC,Ko CY,Chuang JY

Tue Sep 28 00:00:00 UTC 2021

Metformin inhibits MAPK signaling and rescues pancreatic aquaporin 7 expression to induce insulin secretion in type 2 diabetes mellitus.

The Journal of biological chemistry

He X,Gao F,Hou J,Li T,Tan J,Wang C,Liu X,Wang M,Liu H,Chen Y,Yu Z,Yang M

Sun Aug 01 00:00:00 UTC 2021

ORMDL1 is upregulated and associated with favorable outcomes in colorectal cancer.

Translational oncology

Wang Q,Liu W,Chen S,Luo Q,Li Y,Peng S,Wang H,Liu X,Chen D

Fri Oct 01 00:00:00 UTC 2021

Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.

Journal of physiology and biochemistry

Li Y,Zhao Y,Li Y,Zhang X,Li C,Long N,Chen X,Bao L,Zhou J,Xie Y

Mon Feb 01 00:00:00 UTC 2021

The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.

Molecules (Basel, Switzerland)

Chen C,Lv Q,Li Y,Jin YH

Sun Jun 27 00:00:00 UTC 2021

Kindlin-2 Acts as a Key Mediator of Lung Fibroblast Activation and Pulmonary Fibrosis Progression.

American journal of respiratory cell and molecular biology

Zhang P,Wang J,Luo W,Yuan J,Cui C,Guo L,Wu C

Thu Jul 01 00:00:00 UTC 2021

ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer.

Journal of experimental & clinical cancer research : CR

Sun X,He Z,Guo L,Wang C,Lin C,Ye L,Wang X,Li Y,Yang M,Liu S,Hua X,Wen W,Lin C,Long Z,Zhang W,Li H,Jian Y,Zhu Z,Wu X,Lin H

Fri Apr 30 00:00:00 UTC 2021

Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.

Cell death & disease

Chang H,Xu Q,Li J,Li M,Zhang Z,Ma H,Yang X

Wed Jul 21 00:00:00 UTC 2021

Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.

Molecular immunology

Li M,Lu H,Wang X,Duan C,Zhu X,Zhang Y,Ge X,Ji F,Wang X,Su J,Zhang D

Wed Dec 01 00:00:00 UTC 2021

Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis.

Theranostics

Zheng Q,Li P,Zhou X,Qiang Y,Fan J,Lin Y,Chen Y,Guo J,Wang F,Xue H,Xiong J,Li F

Fri Feb 04 00:00:00 UTC 2022

Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy.

ACS nano

Xie S,Sun W,Zhang C,Dong B,Yang J,Hou M,Xiong L,Cai B,Liu X,Xue W

Tue Apr 27 00:00:00 UTC 2021

LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.

Cell death discovery

Li D,Wang X,Li G,Dang Y,Zhao S,Qin Y

Sun May 16 00:00:00 UTC 2021

Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.

Aging

Peng Y,Zhang Z,Zhang A,Liu C,Sun Y,Peng Z,Liu Y

Wed Mar 24 00:00:00 UTC 2021

PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons.

Neurochemistry international

Marcus JM,Hossain MI,Gagné JP,Poirier GG,McMahon LL,Cowell RM,Andrabi SA

Wed Sep 01 00:00:00 UTC 2021

Identification of fusarielin M as a novel inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB).

Bioorganic chemistry

Chen D,Liu L,Lu Y,Chen S

Fri Jan 01 00:00:00 UTC 2021

Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells.

BMC cancer

Amaya C,Luo S,Baigorri J,Baucells R,Smith ER,Xu XX

Wed Sep 01 00:00:00 UTC 2021

NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.

American journal of cancer research

Fan XJ,Wang YL,Zhao WW,Bai SM,Ma Y,Yin XK,Feng LL,Feng WX,Wang YN,Liu Q,Hung MC,Wan XB

Tue Jul 13 00:00:00 UTC 2021

SLC25A21 Suppresses Cell Growth in Bladder Cancer via an Oxidative Stress-Mediated Mechanism.

Frontiers in oncology

Wang Y,Gao J,Hu S,Zeng W,Yang H,Chen H,Wang S

Wed Apr 27 00:00:00 UTC 2022

Androgen-dependent and DNA-binding-independent association of androgen receptor with chromatic regions coding androgen-induced noncoding RNAs.

Bioscience, biotechnology, and biochemistry

Sawada T,Nishimura K,Mori J,Kanemoto Y,Kouzmenko A,Amano R,Hayakawa A,Tokiwa S,Shimmura H,Kato S

Wed Sep 22 00:00:00 UTC 2021

Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.

Frontiers in pharmacology

Tong X,Zhang S,Wang D,Zhang L,Huang J,Zhang T,Fan H

Tue Nov 23 00:00:00 UTC 2021

SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation.

Theranostics

Guan C,Huang X,Yue J,Xiang H,Shaheen S,Jiang Z,Tao Y,Tu J,Liu Z,Yao Y,Yang W,Hou Z,Liu J,Yang XD,Zou Q,Su B,Liu Z,Ni J,Cheng J,Wu X

Thu Jul 29 00:00:00 UTC 2021

Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS.

Communications biology

Deng HX,Zhai H,Shi Y,Liu G,Lowry J,Liu B,Ryan ÉB,Yan J,Yang Y,Zhang N,Yang Z,Liu E,Ma YC,Siddique T

Thu Mar 25 00:00:00 UTC 2021

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity

Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H

Tue Jul 14 00:00:00 UTC 2020

Targeting PML in triple negative breast cancer elicits growth suppression and senescence.

Cell death and differentiation

Arreal L,Piva M,Fernández S,Revandkar A,Schaub-Clerigué A,Villanueva J,Zabala-Letona A,Pujana M,Astobiza I,Cortazar AR,Hermanova I,Bozal-Basterra L,Arruabarrena-Aristorena A,Crespo JR,Valcarcel-Jimenez L,Zúñiga-García P,Canals F,Torrano V,Barrio R,Sutherland JD,Alimonti A,Martin-Martin N,Carracedo A

Wed Apr 01 00:00:00 UTC 2020

USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.

PLoS pathogens

Liu J,Jin L,Chen X,Yuan Y,Zuo Y,Miao Y,Feng Q,Zhang H,Huang F,Guo T,Zhang L,Zhu L,Qian F,Zhu C,Zheng H

Wed Jan 01 00:00:00 UTC 2020

SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells.

Molecular oncology

Dou J,Zhang H,Chen R,Shu Z,Yuan H,Zhao X,Wang Y,Huang J,Zhou A,Yu J

Tue Sep 01 00:00:00 UTC 2020

Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress.

Oncogenesis

Zhang J,Duan H,Feng Z,Han X,Gu C

Tue May 12 00:00:00 UTC 2020

FNDC3B 3'-UTR shortening escapes from microRNA-mediated gene repression and promotes nasopharyngeal carcinoma progression.

Cancer science

Li YQ,Chen Y,Xu YF,He QM,Yang XJ,Li YQ,Hong XH,Huang SY,Tang LL,Liu N

Mon Jun 01 00:00:00 UTC 2020

Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape.

Journal of immunology (Baltimore, Md. : 1950)

Li Z,Wang J,Zhang X,Liu P,Zhang X,Wang J,Zheng X,Wei L,Peng Q,Liu C,Yan Q,Shen S,Li X,Ma J

Fri May 01 00:00:00 UTC 2020

Prohibitin (PHB) interacts with AKT in mitochondria to coordinately modulate sperm motility.

Asian journal of andrology

Li XH,Chai RR,Chen GW,Zhang LF,Tan-Tai WJ,Shi HJ,Martin-DeLeon PA,O WS,Chen H

Wed Sep 22 00:00:00 UTC 2021

ChREBP-β regulates thermogenesis in brown adipose tissue.

The Journal of endocrinology

Wei C,Ma X,Su K,Qi S,Zhu Y,Lin J,Wang C,Yang R,Chen X,Wang W,Zhang WJ

Mon Jun 01 00:00:00 UTC 2020

Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.

Biomaterials

Huang L,Yan W,Cai B,Song Y,Lv Q,Wang G,Wang L,Wang Z

Sat Aug 01 00:00:00 UTC 2020

Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.

International immunopharmacology

Qian G,Zhu L,Huang C,Liu Y,Ren Y,Ding Y,Qian W,Xu Q,Zheng H,Lv H

Thu Oct 01 00:00:00 UTC 2020

Maintaining protein stability of ΔNp63 via USP28 is required by squamous cancer cells.

EMBO molecular medicine

Prieto-Garcia C,Hartmann O,Reissland M,Braun F,Fischer T,Walz S,Schülein-Völk C,Eilers U,Ade CP,Calzado MA,Orian A,Maric HM,Münch C,Rosenfeldt M,Eilers M,Diefenbacher ME

Tue Apr 07 00:00:00 UTC 2020

Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway.

Biomaterials

Ni R,Song G,Fu X,Song R,Li L,Pu W,Gao J,Hu J,Liu Q,He F,Zhang D,Huang G

Sat Feb 01 00:00:00 UTC 2020

Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.

Cancers

Ke C,Hou H,Li J,Su K,Huang C,Lin Y,Lu Z,Du Z,Tan W,Yuan Z

Mon May 04 00:00:00 UTC 2020

Aging

Huang GZ,Wu QQ,Zheng ZN,Shao TR,Chen YC,Zeng WS,Lv XZ

Thu Jun 11 00:00:00 UTC 2020

PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval.

Cell reports

Yong XLH,Cousin MA,Anggono V

Tue Oct 27 00:00:00 UTC 2020

A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation.

Nucleic acids research

Maltby CJ,Schofield JPR,Houghton SD,O'Kelly I,Vargas-Caballero M,Deinhardt K,Coldwell MJ

Fri Sep 25 00:00:00 UTC 2020

Precise and efficient silencing of mutant Kras^G12D by CRISPR-CasRx controls pancreatic cancer progression.

Theranostics

Jiang W,Li H,Liu X,Zhang J,Zhang W,Li T,Liu L,Yu X

Tue Jun 01 00:00:00 UTC 2021

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

Biochemical and biophysical research communications

Miyauchi Y,Kurita A,Yamashita R,Takamatsu T,Ikushiro S,Mackenzie PI,Tanaka Y,Ishii Y

Thu Apr 30 00:00:00 UTC 2020

Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1.

Frontiers in microbiology

Zhang HG,Guo J,Yuan Y,Zuo Y,Liu J,Zhu L,Miao Y,Chen X,Jin L,Huang F,Ren T,He J,Shi W,Wen Z,Zhu C,Zheng H,Dong C,Qian F

Fri Dec 18 00:00:00 UTC 2020

MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.

American journal of physiology. Renal physiology

Ye C,Xiong W,Lei CT,Tang H,Su H,Yi F,Zhang C

Thu Oct 01 00:00:00 UTC 2020

Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Su H,Ye C,Lei CT,Tang H,Zeng JY,Yi F,Zhang C

Wed Jan 01 00:00:00 UTC 2020

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.

Journal of hematology & oncology

Domínguez JM,Pérez-Chacón G,Guillén MJ,Muñoz-Alonso MJ,Somovilla-Crespo B,Cibrián D,Acosta-Iborra B,Adrados M,Muñoz-Calleja C,Cuevas C,Sánchez-Madrid F,Avilés P,Zapata JM

Tue Apr 07 00:00:00 UTC 2020

The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress.

Autophagy

Shim MS,Nettesheim A,Hirt J,Liton PB

Wed Jul 01 00:00:00 UTC 2020

Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.

Acta neuropathologica communications

Tsai MH,Cheng HY,Nian FS,Liu C,Chao NH,Chiang KL,Chen SF,Tsai JW

Tue Jul 14 00:00:00 UTC 2020

Murine Cytomegalovirus Protein pM49 Interacts with pM95 and Is Critical for Viral Late Gene Expression.

Journal of virology

Han T,Hao H,Sleman SS,Xuan B,Tang S,Yue N,Qian Z

Fri Feb 28 00:00:00 UTC 2020

Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.

Frontiers in cell and developmental biology

Zhang T,Li H,Wang K,Xu B,Chen ZN,Bian H

Mon Sep 28 00:00:00 UTC 2020

Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.

Frontiers in immunology

Geng N,Wang X,Yu X,Wang R,Zhu Y,Zhang M,Liu J,Liu Y

Mon Mar 29 00:00:00 UTC 2021

Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.

Frontiers in immunology

Geng N,Wang X,Yu X,Wang R,Zhu Y,Zhang M,Liu J,Liu Y

Mon Mar 29 00:00:00 UTC 2021

The protective effect of rosmarinic acid on myotube formation during myoblast differentiation under heat stress.

In vitro cellular & developmental biology. Animal

Chen KL,Wang Y,Lin ZP,Li HX

Tue Sep 01 00:00:00 UTC 2020

Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos.

Nature communications

Chen M,Zhu Q,Li C,Kou X,Zhao Y,Li Y,Xu R,Yang L,Yang L,Gu L,Wang H,Liu X,Jiang C,Gao S

Tue Apr 14 00:00:00 UTC 2020

Effects of peptidoglycan on the development of steatohepatitis.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Jin M,Lai Y,Zhao P,Shen Q,Su W,Yin Y,Zhang W

Wed Apr 01 00:00:00 UTC 2020

Structural basis for DEAH-helicase activation by G-patch proteins.

Proceedings of the National Academy of Sciences of the United States of America

Studer MK,Ivanović L,Weber ME,Marti S,Jonas S

Tue Mar 31 00:00:00 UTC 2020

METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.

Molecular cell

Zhang C,Chen L,Peng D,Jiang A,He Y,Zeng Y,Xie C,Zhou H,Luo X,Liu H,Chen L,Ren J,Wang W,Zhao Y

Thu Aug 06 00:00:00 UTC 2020

A role of cellular translation regulation associated with toxic Huntingtin protein.

Cellular and molecular life sciences : CMLS

Joag H,Ghatpande V,Desai M,Sarkar M,Raina A,Shinde M,Chitale R,Deo A,Bose T,Majumdar A

Tue Sep 01 00:00:00 UTC 2020

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.

Cell reports

Yomtoubian S,Lee SB,Verma A,Izzo F,Markowitz G,Choi H,Cerchietti L,Vahdat L,Brown KA,Andreopoulou E,Elemento O,Chang J,Inghirami G,Gao D,Ryu S,Mittal V

Tue Jan 21 00:00:00 UTC 2020

MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.

Journal of experimental & clinical cancer research : CR

Sun Z,Zhang Q,Yuan W,Li X,Chen C,Guo Y,Shao B,Dang Q,Zhou Q,Wang Q,Wang G,Liu J,Kan Q

Fri Nov 20 00:00:00 UTC 2020

FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Park SY,Koh HC

Sun Mar 01 00:00:00 UTC 2020

Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo.

Medical science monitor : international medical journal of experimental and clinical research

Sun Y,Pan H,Shen S,Xia Z,Yu Z,Li C,Sun P,Xin C

Thu Jul 16 00:00:00 UTC 2020

SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.

Cell death & disease

Liu H,Xie S,Fang F,Kalvakolanu DV,Xiao W

Wed Jun 10 00:00:00 UTC 2020

Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion.

Science signaling

Lee S,Park H,Zhu PP,Jung SY,Blackstone C,Chang J

Tue Jan 07 00:00:00 UTC 2020

Circular RNA circ_0026359 Enhances Cisplatin Resistance in Gastric Cancer via Targeting miR-1200/POLD4 Pathway.

BioMed research international

Zhang Z,Yu X,Zhou B,Zhang J,Chang J

Wed May 05 00:00:00 UTC 2021

HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation.

Cell stress

Zhao JF,Rodger CE,Allen GFG,Weidlich S,Ganley IG

Wed Mar 04 00:00:00 UTC 2020

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.

Journal of extracellular vesicles

Jiang W,Ma P,Deng L,Liu Z,Wang X,Liu X,Long G

Sat Oct 24 00:00:00 UTC 2020

Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha.

Pharmacology

Yu X,Wang S,Wang J,Gong J,Shi J,Yu S

Wed Feb 03 00:00:00 UTC 2021

Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.

Molecular cell

Yuan Y,Miao Y,Qian L,Zhang Y,Liu C,Liu J,Zuo Y,Feng Q,Guo T,Zhang L,Chen X,Jin L,Huang F,Zhang H,Zhang W,Li W,Xu G,Zheng H

Thu Feb 20 00:00:00 UTC 2020

GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.

Molecular biomedicine

Zhou J,Tan Y,Zhang Y,Tong A,Shen X,Sun X,Jia D,Sun Q

Wed Dec 30 00:00:00 UTC 2020

Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact.

Cell death and differentiation

Tang J,Zhang K,Dong J,Yan C,Hu C,Ji H,Chen L,Chen S,Zhao H,Song Z

Wed Jan 01 00:00:00 UTC 2020

A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.

Fitoterapia

Liu DM,Cao ZX,Yan HL,Li W,Yang F,Zhao WJ,Diao QC,Tan YZ

Sun Mar 01 00:00:00 UTC 2020

Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.

Frontiers in immunology

Wen W,Zhao Q,Yin M,Qin L,Hu J,Chen H,Li X,Qian P

Tue Jun 15 00:00:00 UTC 2021

Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.

Cell death & disease

Zhang Y,Zhao S,Fu Y,Yan L,Feng Y,Chen Y,Wu Y,Deng Y,Zhang G,Chen Z,Chen Y,Liu T

Tue Aug 18 00:00:00 UTC 2020

The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.

Carcinogenesis

Tang H,Chu Y,Huang Z,Cai J,Wang Z

Wed Apr 22 00:00:00 UTC 2020

High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy.

Molecular brain

Su P,Ying M,Han Z,Xia J,Jin S,Li Y,Wang H,Xu F

Mon Jan 13 00:00:00 UTC 2020

A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.

International journal of molecular medicine

Fan J,Ji CC,Cheng YJ,Yao H,Chen XM,Zheng ZH,Wu SH

Sun Mar 01 00:00:00 UTC 2020

ITM2A as a Tumor Suppressor and Its Correlation With PD-L1 in Breast Cancer.

Frontiers in oncology

Zhang R,Xu T,Xia Y,Wang Z,Li X,Chen W

Thu Apr 21 00:00:00 UTC 2022

Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.

Molecular cancer research : MCR

Koppenhafer SL,Goss KL,Terry WW,Gordon DJ

Wed Jan 01 00:00:00 UTC 2020

A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.

Oncogene

Wang X,Wang Y,Li L,Xue X,Xie H,Shi H,Hu Y

Sat Feb 01 00:00:00 UTC 2020

Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells.

British journal of cancer

Teratake Y,Takashina T,Iijima K,Sakuma T,Yamamoto T,Ishizaka Y

Sun Mar 01 00:00:00 UTC 2020

Nuclear import of NLS- RARα is mediated by importin α/β.

Cellular signalling

Ye J,Zhong L,Xiong L,Li J,Yu L,Dan W,Yuan Z,Yao J,Zhong P,Liu J,Liu D,Liu B

Fri May 01 00:00:00 UTC 2020

β-Actin facilitates etoposide-induced p53 nuclear import.

Journal of biosciences

Qi W,Li J,Pei X,Ke Y,Bu Q,Ni X

Fri Nov 13 00:00:00 UTC 2020

Small-molecule inhibitors of ubiquitin-specific protease 7 enhance type-I interferon antiviral efficacy by destabilizing SOCS1.

Immunology

Yuan Y,Miao Y,Zeng C,Liu J,Chen X,Qian L,Wang X,Qian F,Yu Z,Wang J,Qian G,Fu Q,Lv H,Zheng H

Sun Mar 01 00:00:00 UTC 2020

lncMGPF is a novel positive regulator of muscle growth and regeneration.

Journal of cachexia, sarcopenia and muscle

Lv W,Jin J,Xu Z,Luo H,Guo Y,Wang X,Wang S,Zhang J,Zuo H,Bai W,Peng Y,Tang J,Zhao S,Zuo B

Tue Dec 01 00:00:00 UTC 2020

Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity.

Life science alliance

Zachari M,Longo M,Ganley IG

Tue Dec 01 00:00:00 UTC 2020

Melatonin protects mouse testes from palmitic acid-induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1-dependent manner.

Journal of pineal research

Xu D,Liu L,Zhao Y,Yang L,Cheng J,Hua R,Zhang Z,Li Q

Sun Nov 01 00:00:00 UTC 2020

Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.

Biochimica et biophysica acta. Molecular cell research

Tang K,Li S,Li P,Xia Q,Yang R,Li T,Li L,Jiang Y,Qin X,Yang H,Wu C,You F,Tan Y,Liu Y

Fri May 01 00:00:00 UTC 2020

Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.

Clinical science (London, England : 1979)

Sun X,Huang K,Haiming X,Lin Z,Yang Y,Zhang M,Liu P,Huang H

Fri Jul 17 00:00:00 UTC 2020

USP39 Serves as a Deubiquitinase to Stabilize STAT1 and Sustains Type I IFN-Induced Antiviral Immunity.

Journal of immunology (Baltimore, Md. : 1950)

Peng Y,Guo J,Sun T,Fu Y,Zheng H,Dong C,Xiong S

Tue Dec 01 00:00:00 UTC 2020

LncRNA UCA1 maintains the low-tumorigenic and nonmetastatic status by stabilizing E-cadherin in primary prostate cancer cells.

Molecular carcinogenesis

Zhao X,Wang Y,He J,Deng R,Huang X,Guo Y,Li L,Xie R,Yu J

Thu Oct 01 00:00:00 UTC 2020

Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.

Nature communications

Zuo Y,Feng Q,Jin L,Huang F,Miao Y,Liu J,Xu Y,Chen X,Zhang H,Guo T,Yuan Y,Zhang L,Wang J,Zheng H

Mon Mar 02 00:00:00 UTC 2020

MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.

Journal of cellular physiology

Zhang X,Dang Y,Liu R,Zhao S,Ma J,Qin Y

Sun Nov 01 00:00:00 UTC 2020

Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.

Journal of Alzheimer's disease : JAD

Almansoub HAMM,Tang H,Wu Y,Wang DQ,Mahaman YAR,Salissou MTM,Lu Y,Hu F,Zhou LT,Almansob YAM,Liu D

Mon Apr 19 00:00:00 UTC 2021

RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling.

Development (Cambridge, England)

Ma P,An T,Zhu L,Zhang L,Wang H,Ren B,Sun B,Zhou X,Li Y,Mao B

Mon Jun 15 00:00:00 UTC 2020

Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma.

Cancer research

Slemmons KK,Yeung C,Baumgart JT,Juarez JOM,McCalla A,Helman LJ

Wed Jul 15 00:00:00 UTC 2020

Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.

EMBO molecular medicine

Li SB,Liu YY,Yuan L,Ji MF,Zhang A,Li HY,Tang LQ,Fang SG,Zhang H,Xing S,Li MZ,Zhong Q,Lin SJ,Liu WL,Huang P,Zeng YX,Zheng YM,Ling ZQ,Sui JH,Zeng MS

Mon Sep 07 00:00:00 UTC 2020

Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.

Science advances

Guerra J,Valadao AL,Vlachakis D,Polak K,Vila IK,Taffoni C,Prabakaran T,Marriott AS,Kaczmarek R,Houel A,Auzemery B,Déjardin S,Boudinot P,Nawrot B,Jones NJ,Paludan SR,Kossida S,Langevin C,Laguette N

Fri May 01 00:00:00 UTC 2020

RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.

Cell death and differentiation

Zheng T,Zhou H,Li X,Peng D,Yang Y,Zeng Y,Liu H,Ren J,Zhao Y

Sun Nov 01 00:00:00 UTC 2020

GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.

Biochemical and biophysical research communications

Guo S,Ouyang S,Wang X,Liao A,Yuan S

Thu Aug 27 00:00:00 UTC 2020

Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Lin T,Luo W,Li Z,Zhang L,Zheng X,Mai L,Yang W,Guan G,Su Z,Liu P,Li Z,Xie Y

Tue Dec 01 00:00:00 UTC 2020

Generation and Application of Mouse Monoclonal Antibody Against Human Cytomegalovirus UL23.

Viral immunology

Li W,Chai H,Feng L,Deng J,Yang X,Ran Y,Li H

Mon Jun 01 00:00:00 UTC 2020

ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.

Experimental and therapeutic medicine

Li M,Fan Y,Wang Y,Xu J,Xu H

Sat Aug 01 00:00:00 UTC 2020

NAF-1 Inhibition by Resveratrol Suppresses Cancer Stem Cell-Like Properties and the Invasion of Pancreatic Cancer.

Frontiers in oncology

Qin T,Cheng L,Xiao Y,Qian W,Li J,Wu Z,Wang Z,Xu Q,Duan W,Wong L,Wu E,Ma Q,Ma J

Mon Sep 28 00:00:00 UTC 2020

Circular RNA CRIM1 functions as a ceRNA to promote nasopharyngeal carcinoma metastasis and docetaxel chemoresistance through upregulating FOXQ1.

Molecular cancer

Hong X,Liu N,Liang Y,He Q,Yang X,Lei Y,Zhang P,Zhao Y,He S,Wang Y,Li J,Li Q,Ma J,Li Y

Sat Feb 15 00:00:00 UTC 2020

DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway.

Scientific reports

Fujii A,Sunatani Y,Furuichi K,Fujimoto K,Adachi H,Iwabuchi K,Yokoyama H

Thu Dec 17 00:00:00 UTC 2020

Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.

Cell reports

Li S,Wu Z,Li Y,Tantray I,De Stefani D,Mattarei A,Krishnan G,Gao FB,Vogel H,Lu B

Tue Aug 04 00:00:00 UTC 2020

Flavin adenine dinucleotide ameliorates hypertensive vascular remodeling via activating short chain acyl-CoA dehydrogenase.

Life sciences

Zhong X,Ma Z,Su Y,Li Z,Liao Y,Pan X,Zang L,Zhou S

Thu Oct 01 00:00:00 UTC 2020

Initiator and executioner caspases in salivary gland apoptosis of Rhipicephalus haemaphysaloides.

Parasites & vectors

Wang Y,Hu S,Tuerdi M,Yu X,Zhang H,Zhou Y,Cao J,da Silva Vaz I,Zhou J

Fri Jun 05 00:00:00 UTC 2020

Downregulation of miR-146b-5p via iodine involvement repressed papillary thyroid carcinoma cell proliferation.

Journal of molecular endocrinology

Pan Y,Yun W,Shi B,Cui R,Liu C,Ding Z,Fan J,Jiang W,Tang J,Zheng T,Yu X,Liu Y

Sat Aug 01 00:00:00 UTC 2020

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis.

Disease models & mechanisms

Aoudjehane L,Gautheron J,Le Goff W,Goumard C,Gilaizeau J,Nget CS,Savier E,Atif M,Lesnik P,Morichon R,Chrétien Y,Calmus Y,Scatton O,Housset C,Conti F

Wed Apr 29 00:00:00 UTC 2020

WD40 repeat and FYVE domain containing 3 is essential for cardiac development.

Cardiovascular research

Zhang S,Song Z,An L,Liu X,Hu XW,Naz A,Zhou R,Guo X,He L,Zhu H

Mon Jul 01 00:00:00 UTC 2019

WD40 repeat and FYVE domain containing 3 is essential for cardiac development.

Cardiovascular research

Zhang S,Song Z,An L,Liu X,Hu XW,Naz A,Zhou R,Guo X,He L,Zhu H

Mon Jul 01 00:00:00 UTC 2019

Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.

Oncogene

Zhang H,Wang Y,Dou J,Guo Y,He J,Li L,Liu X,Chen R,Deng R,Huang J,Xie R,Zhao X,Yu J

Fri Feb 01 00:00:00 UTC 2019

Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.

Oncogene

Zhang H,Wang Y,Dou J,Guo Y,He J,Li L,Liu X,Chen R,Deng R,Huang J,Xie R,Zhao X,Yu J

Fri Feb 01 00:00:00 UTC 2019

The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma.

Frontiers in oncology

Cheng F,Zhang P,Xiao Q,Li Y,Dong M,Wang H,Kuang D,He Y,Duan Q,Mao F,Wang B,Guo D

Sat Nov 04 00:00:00 UTC 2023

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.

American journal of physiology. Cell physiology

Kang H,Hong Z,Zhong M,Klomp J,Bayless KJ,Mehta D,Karginov AV,Hu G,Malik AB

Tue Jan 01 00:00:00 UTC 2019

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.

American journal of physiology. Cell physiology

Kang H,Hong Z,Zhong M,Klomp J,Bayless KJ,Mehta D,Karginov AV,Hu G,Malik AB

Tue Jan 01 00:00:00 UTC 2019

Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.

Brain structure & function

Otsuka S,Sakakima H,Terashi T,Takada S,Nakanishi K,Kikuchi K

Fri Mar 01 00:00:00 UTC 2019

Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.

Brain structure & function

Otsuka S,Sakakima H,Terashi T,Takada S,Nakanishi K,Kikuchi K

Fri Mar 01 00:00:00 UTC 2019

Genomic Structure of Hstx2 Modifier of Prdm9-Dependent Hybrid Male Sterility in Mice.

Genetics

Lustyk D,Kinský S,Ullrich KK,Yancoskie M,Kašíková L,Gergelits V,Sedlacek R,Chan YF,Odenthal-Hesse L,Forejt J,Jansa P

Fri Nov 01 00:00:00 UTC 2019

Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.

Frontiers in molecular neuroscience

Chang HY,Cheng HY,Tsao AN,Liu C,Tsai JW

Tue Sep 29 00:00:00 UTC 2020

Tranilast enhances the effect of anticancer agents in osteosarcoma.

Oncology reports

Nakashima T,Nagano S,Setoguchi T,Sasaki H,Saitoh Y,Maeda S,Komiya S,Taniguchi N

Mon Jul 01 00:00:00 UTC 2019

CXCL13/CXCR5 signaling contributes to diabetes-induced tactile allodynia via activating pERK, pSTAT3, pAKT pathways and pro-inflammatory cytokines production in the spinal cord of male mice.

Brain, behavior, and immunity

Liu S,Liu X,Xiong H,Wang W,Liu Y,Yin L,Tu C,Wang H,Xiang X,Xu J,Duan B,Tao A,Zhao Z,Mei Z

Thu Aug 01 00:00:00 UTC 2019

Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.

Virology

Wen W,Yin M,Zhang H,Liu T,Chen H,Qian P,Hu J,Li X

Sun Sep 01 00:00:00 UTC 2019

PARP11 regulates total levels of type-I interferon receptor IFNAR1.

Nature microbiology

Guo T,Liu J,Chen X,Jin L,Huang F,Zheng H

Fri Nov 01 00:00:00 UTC 2019

Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes.

Molecular biology of the cell

Colicino EG,Stevens K,Curtis E,Rathbun L,Bates M,Manikas J,Amack J,Freshour J,Hehnly H

Sat Jun 15 00:00:00 UTC 2019

p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.

Biochemical and biophysical research communications

Wang T,Li K,Song H,Xu D,Liao Y,Jing B,Guo W,Hu M,Kuang Y,Sun B,Ling J,Zhang T,Xu J,Yao F,Deng J

Tue May 28 00:00:00 UTC 2019

Pharmacologic Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage.

Molecular cancer research : MCR

Buranasudja V,Doskey CM,Gibson AR,Wagner BA,Du J,Gordon DJ,Koppenhafer SL,Cullen JJ,Buettner GR

Tue Oct 01 00:00:00 UTC 2019

Silver nanoparticles selectively induce human oncogenic γ-herpesvirus-related cancer cell death through reactivating viral lytic replication.

Cell death & disease

Wan C,Tai J,Zhang J,Guo Y,Zhu Q,Ling D,Gu F,Gan J,Zhu C,Wang Y,Liu S,Wei F,Cai Q

Tue May 21 00:00:00 UTC 2019

Proteasome inhibition promotes mono-ubiquitination and nuclear translocation of mature (52 kDa) PINK1.

Biochemical and biophysical research communications

Sun L,Büeler H

Tue Sep 17 00:00:00 UTC 2019

The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole.

The Journal of biological chemistry

Pike CM,Boyer-Andersen R,Kinch LN,Caplan JL,Neunuebel MR

Fri Apr 19 00:00:00 UTC 2019

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

Journal of proteome research

Dayebgadoh G,Sardiu ME,Florens L,Washburn MP

Fri Sep 06 00:00:00 UTC 2019

Synaptic Injury in the Thalamus Accompanies White Matter Injury in Hypoxia/Ischemia-Mediated Brain Injury in Neonatal Rats.

BioMed research international

Liu N,Tong X,Huang W,Fu J,Xue X

Thu Mar 26 00:00:00 UTC 2020

Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.

Frontiers in pharmacology

Zhang J,Li L,Zhang Q,Yang X,Zhang C,Zhang X,Zhang D,Lv Y,Song H,Chen B,Liu Y,Hu J,Huang Y

Thu Oct 01 00:00:00 UTC 2020

Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.

Frontiers in pharmacology

Zhang J,Li L,Zhang Q,Yang X,Zhang C,Zhang X,Zhang D,Lv Y,Song H,Chen B,Liu Y,Hu J,Huang Y

Thu Oct 01 00:00:00 UTC 2020

Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models.

Scientific reports

Vauthier V,Ben Saad A,Elie J,Oumata N,Durand-Schneider AM,Bruneau A,Delaunay JL,Housset C,Aït-Slimane T,Meijer L,Falguières T

Tue Apr 30 00:00:00 UTC 2019

Simultaneous targeting of XPO1 and BCL2 as an effective treatment strategy for double-hit lymphoma.

Journal of hematology & oncology

Liu Y,Azizian NG,Dou Y,Pham LV,Li Y

Thu Nov 21 00:00:00 UTC 2019

SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.

Life sciences

Xu D,Jiang X,He H,Liu D,Yang L,Chen H,Wu L,Geng G,Li Q

Sun Sep 01 00:00:00 UTC 2019

ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.

Nature microbiology

Guo T,Zuo Y,Qian L,Liu J,Yuan Y,Xu K,Miao Y,Feng Q,Chen X,Jin L,Zhang L,Dong C,Xiong S,Zheng H

Fri Nov 01 00:00:00 UTC 2019

Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.

Molecular neurobiology

Nian FS,Li LL,Cheng CY,Wu PC,Lin YT,Tang CY,Ren BS,Tai CY,Fann MJ,Kao LS,Hong CJ,Tsai JW

Sun Sep 01 00:00:00 UTC 2019

CACYBP Enhances Cytoplasmic Retention of P27^Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.

Theranostics

Lian YF,Huang YL,Zhang YJ,Chen DM,Wang JL,Wei H,Bi YH,Jiang ZW,Li P,Chen MS,Huang YH

Mon Sep 14 00:00:00 UTC 2020

Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.

Neurological research

Terashi T,Otsuka S,Takada S,Nakanishi K,Ueda K,Sumizono M,Kikuchi K,Sakakima H

Sat Jun 01 00:00:00 UTC 2019

SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.

International journal of molecular sciences

Xu D,Wu L,Jiang X,Yang L,Cheng J,Chen H,Hua R,Geng G,Yang L,Li Q

Mon Mar 18 00:00:00 UTC 2019

m⁶A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner.

Cell death & disease

Wu R,Liu Y,Zhao Y,Bi Z,Yao Y,Liu Q,Wang F,Wang Y,Wang X

Wed Feb 20 00:00:00 UTC 2019

Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.

Human molecular genetics

Simmons AJ,Park R,Sterling NA,Jang MH,van Deursen JMA,Yen TJ,Cho SH,Kim S

Sat Jun 01 00:00:00 UTC 2019

Kinesin-6 Klp9 plays motor-dependent and -independent roles in collaboration with Kinesin-5 Cut7 and the microtubule crosslinker Ase1 in fission yeast.

Scientific reports

Yukawa M,Okazaki M,Teratani Y,Furuta K,Toda T

Tue May 14 00:00:00 UTC 2019

Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity mediated by Lonp1/Aco2/Hsp75.

Toxicon : official journal of the International Society on Toxinology

Li C,Chen W,Zheng L,Zhang B,Yang X,Zhang Q,Wang N,Wang Y,Yang J,Sha J,Zhou Z,Li X,Li Y,Shen XL

Tue Oct 01 00:00:00 UTC 2019

Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.

eLife

Woo Y,Kim SJ,Suh BK,Kwak Y,Jung HJ,Nhung TTM,Mun DJ,Hong JH,Noh SJ,Kim S,Lee A,Baek ST,Nguyen MD,Choe Y,Park SK

Mon Dec 09 00:00:00 UTC 2019

Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality.

International journal of cardiology

Liu X,Zhang S,An L,Wu J,Hu X,Lai S,Mazhar H,Zou Y,He L,Zhu H

Sun Dec 01 00:00:00 UTC 2019

Vacuolar protein sorting 4 is required for silkworm metamorphosis.

Insect molecular biology

Xia H,Chen L,Shao D,Liu X,Wang Q,Zhu F,Guo Z,Gao L,Chen K

Tue Oct 01 00:00:00 UTC 2019

Neferine in the Lotus Plumule Potentiates the Antitumor Effect of Imatinib in Primary Chronic Myeloid Leukemia Cells In Vitro.

Journal of food science

Zhang Y,Xiao Y,Dong Q,Ouyang W,Qin Q

Mon Apr 01 00:00:00 UTC 2019

Dissecting the Role of DDX21 in Regulating Human Cytomegalovirus Replication.

Journal of virology

Hao H,Han T,Xuan B,Sun Y,Tang S,Yue N,Qian Z

Sun Dec 15 00:00:00 UTC 2019

Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.

Cell reports

Zhu Q,Ding L,Zi Z,Gao S,Wang C,Wang Y,Zhu C,Yuan Z,Wei F,Cai Q

Tue Mar 26 00:00:00 UTC 2019

NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.

Scientific reports

Martin-Hurtado A,Martin-Morales R,Robledinos-Antón N,Blanco R,Palacios-Blanco I,Lastres-Becker I,Cuadrado A,Garcia-Gonzalo FR

Wed Sep 25 00:00:00 UTC 2019

Seneca Valley Virus 2C and 3C^pro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.

Frontiers in microbiology

Liu T,Li X,Wu M,Qin L,Chen H,Qian P

Thu Oct 01 00:00:00 UTC 2020

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.

Developmental cell

Chang CH,Zanini M,Shirvani H,Cheng JS,Yu H,Feng CH,Mercier AL,Hung SY,Forget A,Wang CH,Cigna SM,Lu IL,Chen WY,Leboucher S,Wang WJ,Ruat M,Spassky N,Tsai JW,Ayrault O

Mon Jan 28 00:00:00 UTC 2019

Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.

eLife

Adams CR,Htwe HH,Marsh T,Wang AL,Montoya ML,Subbaraj L,Tward AD,Bardeesy N,Perera RM

Tue May 28 00:00:00 UTC 2019

Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor.

The international journal of biochemistry & cell biology

Yu X,Wu J,Hu M,Wu J,Zhu Q,Yang Z,Xie X,Feng YQ,Yue J

Wed May 01 00:00:00 UTC 2019

DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella.

Clinical genetics

Li Y,Sha Y,Wang X,Ding L,Liu W,Ji Z,Mei L,Huang X,Lin S,Kong S,Lu J,Qin W,Zhang X,Zhuang J,Tang Y,Lu Z

Wed May 01 00:00:00 UTC 2019

CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.

BMC cancer

Li H,Jin X,Liu B,Zhang P,Chen W,Li Q

Thu Aug 22 00:00:00 UTC 2019

Preparation and identification of polyclonal antibody against human cytomegalovirus encoding protein UL23.

Protein expression and purification

Chai H,Wu S,Deng J,Feng L,Yang X,Ran Y,Li H

Sun Sep 01 00:00:00 UTC 2019

ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade.

International journal of molecular sciences

Tsai YT,Wu AC,Yang WB,Kao TJ,Chuang JY,Chang WC,Hsu TI

Mon Nov 11 00:00:00 UTC 2019

TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.

Cell death & disease

Lu H,Xiao J,Ke C,Ni X,Xiu R,Tian Q,Pan H,Zou L,Wang F,Ma T,Ji X,Yuan P,Liu L,Zhang J,Jia W,Duan Q,Zhu F

Mon Aug 05 00:00:00 UTC 2019

Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis.

Cell reports

Wang Y,Guo Y,Tang C,Han X,Xu M,Sun J,Zhao Y,Zhang Y,Wang M,Cao X,Zhu X,Guo W

Tue Dec 03 00:00:00 UTC 2019

NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury.

American journal of physiology. Renal physiology

Xu D,Chen P,Wang B,Wang Y,Miao N,Yin F,Cheng Q,Zhou Z,Xie H,Zhou L,Liu J,Wang X,Zent R,Lu L,Zhang W

Fri Feb 01 00:00:00 UTC 2019

NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury.

American journal of physiology. Renal physiology

Xu D,Chen P,Wang B,Wang Y,Miao N,Yin F,Cheng Q,Zhou Z,Xie H,Zhou L,Liu J,Wang X,Zent R,Lu L,Zhang W

Fri Feb 01 00:00:00 UTC 2019

Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.

Cell communication and signaling : CCS

Hanáková K,Bernatík O,Kravec M,Micka M,Kumar J,Harnoš J,Ovesná P,Paclíková P,Rádsetoulal M,Potěšil D,Tripsianes K,Čajánek L,Zdráhal Z,Bryja V

Mon Dec 23 00:00:00 UTC 2019

The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.

Nature medicine

Ji YX,Huang Z,Yang X,Wang X,Zhao LP,Wang PX,Zhang XJ,Alves-Bezerra M,Cai L,Zhang P,Lu YX,Bai L,Gao MM,Zhao H,Tian S,Wang Y,Huang ZX,Zhu XY,Zhang Y,Gong J,She ZG,Li F,Cohen DE,Li H

Thu Feb 01 00:00:00 UTC 2018

The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.

Nature medicine

Ji YX,Huang Z,Yang X,Wang X,Zhao LP,Wang PX,Zhang XJ,Alves-Bezerra M,Cai L,Zhang P,Lu YX,Bai L,Gao MM,Zhao H,Tian S,Wang Y,Huang ZX,Zhu XY,Zhang Y,Gong J,She ZG,Li F,Cohen DE,Li H

Thu Feb 01 00:00:00 UTC 2018

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.

Cancer cell

Zhu D,Osuka S,Zhang Z,Reichert ZR,Yang L,Kanemura Y,Jiang Y,You S,Zhang H,Devi NS,Bhattacharya D,Takano S,Gillespie GY,Macdonald T,Tan C,Nishikawa R,Nelson WG,Olson JJ,Van Meir EG

Mon Jun 11 00:00:00 UTC 2018

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.

Cancer cell

Zhu D,Osuka S,Zhang Z,Reichert ZR,Yang L,Kanemura Y,Jiang Y,You S,Zhang H,Devi NS,Bhattacharya D,Takano S,Gillespie GY,Macdonald T,Tan C,Nishikawa R,Nelson WG,Olson JJ,Van Meir EG

Mon Jun 11 00:00:00 UTC 2018

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.

Cell metabolism

Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC

Tue Apr 03 00:00:00 UTC 2018

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.

Cell metabolism

Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC

Tue Apr 03 00:00:00 UTC 2018

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.

Cell metabolism

McWilliams TG,Prescott AR,Montava-Garriga L,Ball G,Singh F,Barini E,Muqit MMK,Brooks SP,Ganley IG

Tue Feb 06 00:00:00 UTC 2018

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.

Cell metabolism

McWilliams TG,Prescott AR,Montava-Garriga L,Ball G,Singh F,Barini E,Muqit MMK,Brooks SP,Ganley IG

Tue Feb 06 00:00:00 UTC 2018

Zc3h13 Regulates Nuclear RNA m⁶A Methylation and Mouse Embryonic Stem Cell Self-Renewal.

Molecular cell

Wen J,Lv R,Ma H,Shen H,He C,Wang J,Jiao F,Liu H,Yang P,Tan L,Lan F,Shi YG,He C,Shi Y,Diao J

Thu Mar 15 00:00:00 UTC 2018

Zc3h13 Regulates Nuclear RNA m⁶A Methylation and Mouse Embryonic Stem Cell Self-Renewal.

Molecular cell

Wen J,Lv R,Ma H,Shen H,He C,Wang J,Jiao F,Liu H,Yang P,Tan L,Lan F,Shi YG,He C,Shi Y,Diao J

Thu Mar 15 00:00:00 UTC 2018

RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.

Proceedings of the National Academy of Sciences of the United States of America

Kincaid RP,Lam VL,Chirayil RP,Randall G,Sullivan CS

Tue Aug 07 00:00:00 UTC 2018

RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.

Proceedings of the National Academy of Sciences of the United States of America

Kincaid RP,Lam VL,Chirayil RP,Randall G,Sullivan CS

Tue Aug 07 00:00:00 UTC 2018

The Protective Role of Brain CYP2J in Parkinson's Disease Models.

Oxidative medicine and cellular longevity

Li Y,Wu J,Yu X,Na S,Li K,Yang Z,Xie X,Yang J,Yue J

Mon Oct 22 00:00:00 UTC 2018

The Protective Role of Brain CYP2J in Parkinson's Disease Models.

Oxidative medicine and cellular longevity

Li Y,Wu J,Yu X,Na S,Li K,Yang Z,Xie X,Yang J,Yue J

Mon Oct 22 00:00:00 UTC 2018

Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents.

European journal of medicinal chemistry

Zhang L,Zhao Y,Wang J,Yang D,Zhao C,Wang C,Ma C,Cheng M

Thu May 10 00:00:00 UTC 2018

Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents.

European journal of medicinal chemistry

Zhang L,Zhao Y,Wang J,Yang D,Zhao C,Wang C,Ma C,Cheng M

Thu May 10 00:00:00 UTC 2018

Murine Cytomegalovirus Protein pM91 Interacts with pM79 and Is Critical for Viral Late Gene Expression.

Journal of virology

Pan D,Han T,Tang S,Xu W,Bao Q,Sun Y,Xuan B,Qian Z

Sat Sep 15 00:00:00 UTC 2018

Murine Cytomegalovirus Protein pM91 Interacts with pM79 and Is Critical for Viral Late Gene Expression.

Journal of virology

Pan D,Han T,Tang S,Xu W,Bao Q,Sun Y,Xuan B,Qian Z

Sat Sep 15 00:00:00 UTC 2018

PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.

Journal of cellular physiology

Liu Y,Wang JX,Huang D,Wang B,Li LL,Li XX,Ni P,Dong XL,Xia W,Yu CX,Xu WL,Chu WF,Zhao D

Sat Dec 01 00:00:00 UTC 2018

PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.

Journal of cellular physiology

Liu Y,Wang JX,Huang D,Wang B,Li LL,Li XX,Ni P,Dong XL,Xia W,Yu CX,Xu WL,Chu WF,Zhao D

Sat Dec 01 00:00:00 UTC 2018

Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity.

Frontiers in molecular neuroscience

Chen YA,Lu IL,Tsai JW

Thu Oct 01 00:00:00 UTC 2020

Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity.

Frontiers in molecular neuroscience

Chen YA,Lu IL,Tsai JW

Thu Oct 01 00:00:00 UTC 2020

mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells.

Molecular cancer therapeutics

Koppenhafer SL,Goss KL,Terry WW,Gordon DJ

Sat Dec 01 00:00:00 UTC 2018

mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells.

Molecular cancer therapeutics

Koppenhafer SL,Goss KL,Terry WW,Gordon DJ

Sat Dec 01 00:00:00 UTC 2018

Deletion of the stress-response protein REDD1 promotes ceramide-induced retinal cell death and JNK activation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Dai W,Miller WP,Toro AL,Black AJ,Dierschke SK,Feehan RP,Kimball SR,Dennis MD

Tue Jun 19 00:00:00 UTC 2018

Deletion of the stress-response protein REDD1 promotes ceramide-induced retinal cell death and JNK activation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Dai W,Miller WP,Toro AL,Black AJ,Dierschke SK,Feehan RP,Kimball SR,Dennis MD

Tue Jun 19 00:00:00 UTC 2018

AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang P,Song Y,Sun Y,Li X,Chen L,Yang L,Xing Y

Sun Jul 01 00:00:00 UTC 2018

AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang P,Song Y,Sun Y,Li X,Chen L,Yang L,Xing Y

Sun Jul 01 00:00:00 UTC 2018

UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment.

Molecular neurobiology

Yu Q,Zhang H,Li Y,Liu C,Wang S,Liao X

Tue May 01 00:00:00 UTC 2018

UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment.

Molecular neurobiology

Yu Q,Zhang H,Li Y,Liu C,Wang S,Liao X

Tue May 01 00:00:00 UTC 2018

Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.

Proteomics

Wang X,Wen Y,Dong J,Cao C,Yuan S

Sun Jul 01 00:00:00 UTC 2018

Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.

Proteomics

Wang X,Wen Y,Dong J,Cao C,Yuan S

Sun Jul 01 00:00:00 UTC 2018

Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.

Proteomics

Wang X,Wen Y,Dong J,Cao C,Yuan S

Sun Jul 01 00:00:00 UTC 2018

Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.

Journal of cell science

Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW

Mon Dec 17 00:00:00 UTC 2018

Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.

Journal of cell science

Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW

Mon Dec 17 00:00:00 UTC 2018

miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.

Journal of physiology and biochemistry

Chen C,Deng Y,Hu X,Ren H,Zhu J,Fu S,Xie J,Peng Y

Wed Aug 01 00:00:00 UTC 2018

miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.

Journal of physiology and biochemistry

Chen C,Deng Y,Hu X,Ren H,Zhu J,Fu S,Xie J,Peng Y

Wed Aug 01 00:00:00 UTC 2018

ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.

Journal of cellular biochemistry

Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D

Sun Apr 01 00:00:00 UTC 2018

ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.

Journal of cellular biochemistry

Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D

Sun Apr 01 00:00:00 UTC 2018

A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.

DNA and cell biology

Cui X,Zhou Z,Zhu K,Feng R,Han J,Li M,Wang S,Li J,Zhang J,Jiang Q,Zhang W,Mu H,Liu Y,Hu Y

Tue May 01 00:00:00 UTC 2018

A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.

DNA and cell biology

Cui X,Zhou Z,Zhu K,Feng R,Han J,Li M,Wang S,Li J,Zhang J,Jiang Q,Zhang W,Mu H,Liu Y,Hu Y

Tue May 01 00:00:00 UTC 2018

Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.

Biochemical and biophysical research communications

Jheng GW,Hur SS,Chang CM,Wu CC,Cheng JS,Lee HH,Chung BC,Wang YK,Lin KH,Del Álamo JC,Chien S,Tsai JW

Sun Mar 11 00:00:00 UTC 2018

Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.

Biochemical and biophysical research communications

Jheng GW,Hur SS,Chang CM,Wu CC,Cheng JS,Lee HH,Chung BC,Wang YK,Lin KH,Del Álamo JC,Chien S,Tsai JW

Sun Mar 11 00:00:00 UTC 2018

Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.

Biochemical and biophysical research communications

Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H

Fri Apr 06 00:00:00 UTC 2018

Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.

Biochemical and biophysical research communications

Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H

Fri Apr 06 00:00:00 UTC 2018

Ifi27 is indispensable for mitochondrial function and browning in adipocytes.

Biochemical and biophysical research communications

Jin W,Jin W,Pan D

Mon Jun 18 00:00:00 UTC 2018

Ifi27 is indispensable for mitochondrial function and browning in adipocytes.

Biochemical and biophysical research communications

Jin W,Jin W,Pan D

Mon Jun 18 00:00:00 UTC 2018

MCPIP1 is a positive regulator of type I interferons antiviral activity.

Biochemical and biophysical research communications

Qian L,Zuo Y,Deng W,Miao Y,Liu J,Yuan Y,Guo T,Zhang L,Jin J,Wang J,Zheng H

Sun Apr 15 00:00:00 UTC 2018

MCPIP1 is a positive regulator of type I interferons antiviral activity.

Biochemical and biophysical research communications

Qian L,Zuo Y,Deng W,Miao Y,Liu J,Yuan Y,Guo T,Zhang L,Jin J,Wang J,Zheng H

Sun Apr 15 00:00:00 UTC 2018

Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling.

Evidence-based complementary and alternative medicine : eCAM

Tang Y,Huang W,Song Q,Zheng X,He R,Liu J

Sat Apr 09 00:00:00 UTC 2022

Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling.

Evidence-based complementary and alternative medicine : eCAM

Tang Y,Huang W,Song Q,Zheng X,He R,Liu J

Sat Apr 09 00:00:00 UTC 2022

Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy.

Drug design, development and therapy

Zhang M,Yan Z,Bu L,An C,Wang D,Liu X,Zhang J,Yang W,Deng B,Xie J,Zhang B

Mon Oct 29 00:00:00 UTC 2018

Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy.

Drug design, development and therapy

Zhang M,Yan Z,Bu L,An C,Wang D,Liu X,Zhang J,Yang W,Deng B,Xie J,Zhang B

Mon Oct 29 00:00:00 UTC 2018

A growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5⁺ intestinal stem cell maintenance.

Cell discovery

Li Y,Liu Y,Liu B,Wang J,Wei S,Qi Z,Wang S,Fu W,Chen YG

Thu Oct 01 00:00:00 UTC 2020

A growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5⁺ intestinal stem cell maintenance.

Cell discovery

Li Y,Liu Y,Liu B,Wang J,Wei S,Qi Z,Wang S,Fu W,Chen YG

Thu Oct 01 00:00:00 UTC 2020

Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.

The Journal of biological chemistry

Mana-Capelli S,McCollum D

Fri Nov 23 00:00:00 UTC 2018

Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.

The Journal of biological chemistry

Mana-Capelli S,McCollum D

Fri Nov 23 00:00:00 UTC 2018

Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.

FEBS letters

Jiang D,Zou X,Zhang C,Chen J,Li Z,Wang Y,Deng Z,Wang L,Chen S

Sun Apr 01 00:00:00 UTC 2018

EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.

Cell death & disease

Peng Q,Chen L,Wu W,Wang J,Zheng X,Chen Z,Jiang Q,Han J,Wei L,Wang L,Huang J,Ma J

Mon Nov 19 00:00:00 UTC 2018

EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.

Cell death & disease

Peng Q,Chen L,Wu W,Wang J,Zheng X,Chen Z,Jiang Q,Han J,Wei L,Wang L,Huang J,Ma J

Mon Nov 19 00:00:00 UTC 2018

Low-dose paclitaxel downregulates MYC proto-oncogene bHLH transcription factor expression in colorectal carcinoma cells.

Oncology letters

Li W,Zhu W,Lv C,Qu H,Xu K,Li H,Li H,Du Y,Liu G,Wang Y,Wei HJ,Zhao HY

Thu Feb 01 00:00:00 UTC 2018

Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.

EBioMedicine

Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W

Fri Jun 01 00:00:00 UTC 2018

Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.

EBioMedicine

Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W

Fri Jun 01 00:00:00 UTC 2018

CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.

International journal of molecular sciences

Shi WP,Ju D,Li H,Yuan L,Cui J,Luo D,Chen ZN,Bian H

Tue Apr 10 00:00:00 UTC 2018

CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.

International journal of molecular sciences

Shi WP,Ju D,Li H,Yuan L,Cui J,Luo D,Chen ZN,Bian H

Tue Apr 10 00:00:00 UTC 2018

MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.

Cell death & disease

Dang Y,Wang X,Hao Y,Zhang X,Zhao S,Ma J,Qin Y,Chen ZJ

Wed Jan 24 00:00:00 UTC 2018

MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.

Cell death & disease

Dang Y,Wang X,Hao Y,Zhang X,Zhao S,Ma J,Qin Y,Chen ZJ

Wed Jan 24 00:00:00 UTC 2018

High-Content Screening of a Taiwanese Indigenous Plant Extract Library Identifies Syzygium simile leaf Extract as an Inhibitor of Fatty Acid Uptake.

International journal of molecular sciences

Yen CH,Chang HS,Yang TH,Wang SF,Wu HC,Chen YC,Lin KJ,Wang S

Sun Jul 22 00:00:00 UTC 2018

High-Content Screening of a Taiwanese Indigenous Plant Extract Library Identifies Syzygium simile leaf Extract as an Inhibitor of Fatty Acid Uptake.

International journal of molecular sciences

Yen CH,Chang HS,Yang TH,Wang SF,Wu HC,Chen YC,Lin KJ,Wang S

Sun Jul 22 00:00:00 UTC 2018

Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.

Aging

Lian YF,Huang YL,Wang JL,Deng MH,Xia TL,Zeng MS,Chen MS,Wang HB,Huang YH

Thu Aug 09 00:00:00 UTC 2018

Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.

Aging

Lian YF,Huang YL,Wang JL,Deng MH,Xia TL,Zeng MS,Chen MS,Wang HB,Huang YH

Thu Aug 09 00:00:00 UTC 2018

Quercetin attenuates AZT-induced neuroinflammation in the CNS.

Scientific reports

Yang Y,Liu X,Wu T,Zhang W,Shu J,He Y,Tang SJ

Wed Apr 18 00:00:00 UTC 2018

Quercetin attenuates AZT-induced neuroinflammation in the CNS.

Scientific reports

Yang Y,Liu X,Wu T,Zhang W,Shu J,He Y,Tang SJ

Wed Apr 18 00:00:00 UTC 2018

Legumain, an asparaginyl endopeptidase, mediates the effect of M2 macrophages on attenuating renal interstitial fibrosis in obstructive nephropathy.

Kidney international

Wang D,Xiong M,Chen C,Du L,Liu Z,Shi Y,Zhang M,Gong J,Song X,Xiang R,Liu E,Tan X

Sun Jul 01 00:00:00 UTC 2018

Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.

Cell death & disease

Huang Y,Wang H,Lian Y,Wu X,Zhou L,Wang J,Deng M,Huang Y

Fri Feb 02 00:00:00 UTC 2018

Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.

Cell death & disease

Huang Y,Wang H,Lian Y,Wu X,Zhou L,Wang J,Deng M,Huang Y

Fri Feb 02 00:00:00 UTC 2018

β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.

Frontiers in immunology

Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H

Fri Oct 25 00:00:00 UTC 2019

β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.

Frontiers in immunology

Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H

Fri Oct 25 00:00:00 UTC 2019

ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.

Journal of immunology (Baltimore, Md. : 1950)

Feng Q,Miao Y,Ge J,Yuan Y,Zuo Y,Qian L,Liu J,Cheng Q,Guo T,Zhang L,Yu Z,Zheng H

Sun Jul 15 00:00:00 UTC 2018

Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.

Science China. Life sciences

Wang L,Liu L,Qin L,Luo Q,Zhang Z

Sat Apr 01 00:00:00 UTC 2017

Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.

Science China. Life sciences

Wang L,Liu L,Qin L,Luo Q,Zhang Z

Sat Apr 01 00:00:00 UTC 2017

Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.

Antiviral research

Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H

Tue Aug 01 00:00:00 UTC 2017

Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.

Antiviral research

Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H

Tue Aug 01 00:00:00 UTC 2017

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.

Journal of virology

Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE

Fri Dec 15 00:00:00 UTC 2017

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.

Journal of virology

Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE

Fri Dec 15 00:00:00 UTC 2017

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.

International journal of molecular medicine

Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J

Wed Nov 01 00:00:00 UTC 2017

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.

International journal of molecular medicine

Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J

Wed Nov 01 00:00:00 UTC 2017

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.

International journal of molecular medicine

Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J

Wed Nov 01 00:00:00 UTC 2017

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.

International journal of molecular medicine

Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J

Wed Nov 01 00:00:00 UTC 2017

Antithrombin III prevents progression of chronic kidney disease following experimental ischaemic-reperfusion injury.

Journal of cellular and molecular medicine

Yin J,Wang F,Kong Y,Wu R,Zhang G,Wang N,Wang L,Lu Z,Liang M

Fri Dec 01 00:00:00 UTC 2017

Antithrombin III prevents progression of chronic kidney disease following experimental ischaemic-reperfusion injury.

Journal of cellular and molecular medicine

Yin J,Wang F,Kong Y,Wu R,Zhang G,Wang N,Wang L,Lu Z,Liang M

Fri Dec 01 00:00:00 UTC 2017

MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.

Journal of cellular and molecular medicine

Tang H,Lei CT,Ye C,Gao P,Wan C,Chen S,He FF,Wang YM,Su H,Zhang C

Fri Dec 01 00:00:00 UTC 2017

MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.

Journal of cellular and molecular medicine

Tang H,Lei CT,Ye C,Gao P,Wan C,Chen S,He FF,Wang YM,Su H,Zhang C

Fri Dec 01 00:00:00 UTC 2017

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Human molecular genetics

Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J

Fri Dec 15 00:00:00 UTC 2017

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Human molecular genetics

Fri Dec 15 00:00:00 UTC 2017

IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.

Endocrinology

Dang X,Zhu Q,He Y,Wang Y,Lu Y,Li X,Qi J,Wu H,Sun Y

Sun Oct 01 00:00:00 UTC 2017

IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.

Endocrinology

Dang X,Zhu Q,He Y,Wang Y,Lu Y,Li X,Qi J,Wu H,Sun Y

Sun Oct 01 00:00:00 UTC 2017

TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.

Molecular immunology

Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P

Wed Feb 01 00:00:00 UTC 2017

TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.

Molecular immunology

Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P

Wed Feb 01 00:00:00 UTC 2017

HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells.

Experimental cell research

Shang Y,Chen H,Ye J,Wei X,Liu S,Wang R

Wed Nov 15 00:00:00 UTC 2017

HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells.

Experimental cell research

Shang Y,Chen H,Ye J,Wei X,Liu S,Wang R

Wed Nov 15 00:00:00 UTC 2017

Hydrogen peroxide promotes the expression of angiopoietin like 4 in RAW264.7 macrophages via MAPK pathways.

Molecular medicine reports

Liu N,Cui C,Sun Y,Zhang F,Wang S,Su G,Cai X

Wed Nov 01 00:00:00 UTC 2017

Co-expression of podoplanin and fibroblast growth factor 1 predicts poor prognosis in patients with lung squamous cell carcinoma.

Molecular medicine reports

Li J,Chen H,Li X,Wang L,Gao A,Zhang P,Lin W,Gao W,Yang D,Guo X,Liu J,Dang Q,Sun Y

Tue Aug 01 00:00:00 UTC 2017

Co-expression of podoplanin and fibroblast growth factor 1 predicts poor prognosis in patients with lung squamous cell carcinoma.

Molecular medicine reports

Li J,Chen H,Li X,Wang L,Gao A,Zhang P,Lin W,Gao W,Yang D,Guo X,Liu J,Dang Q,Sun Y

Tue Aug 01 00:00:00 UTC 2017

Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.

Molecular medicine reports

Wang Y,Gu YH,Liu M,Bai Y,Wang HL

Wed Feb 01 00:00:00 UTC 2017

Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.

Molecular medicine reports

Wang Y,Gu YH,Liu M,Bai Y,Wang HL

Wed Feb 01 00:00:00 UTC 2017

CMIP Promotes Proliferation and Metastasis in Human Glioma.

BioMed research international

Wang B,Wu ZS,Wu Q

Mon Apr 16 00:00:00 UTC 2018

CMIP Promotes Proliferation and Metastasis in Human Glioma.

BioMed research international

Wang B,Wu ZS,Wu Q

Mon Apr 16 00:00:00 UTC 2018

Tectorigenin attenuates the MPP⁺-induced SH-SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition.

Experimental and therapeutic medicine

Gong P,Deng F,Zhang W,Ji J,Liu J,Sun Y,Hu J

Wed Nov 01 00:00:00 UTC 2017

Tectorigenin attenuates the MPP⁺-induced SH-SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition.

Experimental and therapeutic medicine

Gong P,Deng F,Zhang W,Ji J,Liu J,Sun Y,Hu J

Wed Nov 01 00:00:00 UTC 2017

Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.

Cell death & disease

Xie P,Yang JP,Cao Y,Peng LX,Zheng LS,Sun R,Meng DF,Wang MY,Mei Y,Qiang YY,Cao L,Xiang YQ,Luo DH,Yun JP,Huang BJ,Jia LJ,Qian CN

Thu Jun 01 00:00:00 UTC 2017

Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.

Cell death & disease

Xie P,Yang JP,Cao Y,Peng LX,Zheng LS,Sun R,Meng DF,Wang MY,Mei Y,Qiang YY,Cao L,Xiang YQ,Luo DH,Yun JP,Huang BJ,Jia LJ,Qian CN

Thu Jun 01 00:00:00 UTC 2017

HTLV-1 Tax upregulates early growth response protein 1 through nuclear factor-κB signaling.

Oncotarget

Huang Q,Niu Z,Han J,Liu X,Lv Z,Li H,Yuan L,Li X,Sun S,Wang H,Huang X

Tue Aug 01 00:00:00 UTC 2017

Identification and Characterization of BmVta1, a Bombyx mori (Lepidoptera: Bombycidae) Homologue for Vta1 That is Up-Regulated in Development.

Journal of insect science (Online)

Xia H,Shao D,Liu X,Wang Q,Zhou Y,Chen K

Mon May 01 00:00:00 UTC 2017

Identification and Characterization of BmVta1, a Bombyx mori (Lepidoptera: Bombycidae) Homologue for Vta1 That is Up-Regulated in Development.

Journal of insect science (Online)

Xia H,Shao D,Liu X,Wang Q,Zhou Y,Chen K

Mon May 01 00:00:00 UTC 2017

A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.

Scientific reports

Pirone L,Xolalpa W,Sigurðsson JO,Ramirez J,Pérez C,González M,de Sabando AR,Elortza F,Rodriguez MS,Mayor U,Olsen JV,Barrio R,Sutherland JD

Wed Jan 18 00:00:00 UTC 2017

A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.

Scientific reports

Pirone L,Xolalpa W,Sigurðsson JO,Ramirez J,Pérez C,González M,de Sabando AR,Elortza F,Rodriguez MS,Mayor U,Olsen JV,Barrio R,Sutherland JD

Wed Jan 18 00:00:00 UTC 2017

SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.

Journal of hematology & oncology

Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M

Thu Jun 08 00:00:00 UTC 2017

SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.

Journal of hematology & oncology

Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M

Thu Jun 08 00:00:00 UTC 2017

SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.

Journal of hematology & oncology

Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M

Thu Jun 08 00:00:00 UTC 2017

SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.

Journal of hematology & oncology

Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M

Thu Jun 08 00:00:00 UTC 2017

SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis.

Molecular cancer

Yuan H,Deng R,Zhao X,Chen R,Hou G,Zhang H,Wang Y,Xu M,Jiang B,Yu J

Wed Oct 11 00:00:00 UTC 2017

Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling.

Scientific reports

Wu T,Zhang J,Geng M,Tang SJ,Zhang W,Shu J

Fri Jun 23 00:00:00 UTC 2017

Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling.

Scientific reports

Wu T,Zhang J,Geng M,Tang SJ,Zhang W,Shu J

Fri Jun 23 00:00:00 UTC 2017

Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.

Scientific reports

Zhang C,Mao HL,Cao Y

Mon Jun 19 00:00:00 UTC 2017

Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.

Scientific reports

Zhang C,Mao HL,Cao Y

Mon Jun 19 00:00:00 UTC 2017

MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors.

Scientific reports

Ji HP,Xiong Y,Song WT,Zhang ED,Gao ZL,Yao F,Su T,Zhou RR,Xia XB

Tue Sep 12 00:00:00 UTC 2017

MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors.

Scientific reports

Ji HP,Xiong Y,Song WT,Zhang ED,Gao ZL,Yao F,Su T,Zhou RR,Xia XB

Tue Sep 12 00:00:00 UTC 2017

Suppression of nuclear factor erythroid‑2‑related factor 2‑mediated antioxidative defense in the lung injury induced by chronic exposure to methamphetamine in rats.

Molecular medicine reports

Bai Y,Wang Y,Liu M,Gu YH,Jiang B,Wu X,Wang HL

Mon May 01 00:00:00 UTC 2017

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling.

Oncotarget

Wang JL,Qi Z,Li YH,Zhao HM,Chen YG,Fu W

Tue Sep 19 00:00:00 UTC 2017

TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling.

Oncotarget

Wang JL,Qi Z,Li YH,Zhao HM,Chen YG,Fu W

Tue Sep 19 00:00:00 UTC 2017

NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival.

Scientific reports

Nakano M,Tamura Y,Yamato M,Kume S,Eguchi A,Takata K,Watanabe Y,Kataoka Y

Tue Feb 14 00:00:00 UTC 2017

NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival.

Scientific reports

Nakano M,Tamura Y,Yamato M,Kume S,Eguchi A,Takata K,Watanabe Y,Kataoka Y

Tue Feb 14 00:00:00 UTC 2017

The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.

The Journal of biological chemistry

de Castro RO,Previato L,Goitea V,Felberg A,Guiraldelli MF,Filiberti A,Pezza RJ

Fri May 19 00:00:00 UTC 2017

The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.

The Journal of biological chemistry

de Castro RO,Previato L,Goitea V,Felberg A,Guiraldelli MF,Filiberti A,Pezza RJ

Fri May 19 00:00:00 UTC 2017

Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner.

Frontiers in cellular and infection microbiology

Allgood SC,Romero Dueñas BP,Noll RR,Pike C,Lein S,Neunuebel MR

Fri May 18 00:00:00 UTC 2018

Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner.

Frontiers in cellular and infection microbiology

Allgood SC,Romero Dueñas BP,Noll RR,Pike C,Lein S,Neunuebel MR

Fri May 18 00:00:00 UTC 2018

Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zuo T,Zhu M,Xu W,Wang Z,Song H

Mon Jan 22 00:00:00 UTC 2018

Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zuo T,Zhu M,Xu W,Wang Z,Song H

Mon Jan 22 00:00:00 UTC 2018

Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts.

Scientific reports

Liu X,Zuo R,Bao Y,Qu X,Sun K,Ying H

Wed Aug 16 00:00:00 UTC 2017

Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts.

Scientific reports

Liu X,Zuo R,Bao Y,Qu X,Sun K,Ying H

Wed Aug 16 00:00:00 UTC 2017

Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine.

Oncotarget

Goss KL,Koppenhafer SL,Harmoney KM,Terry WW,Gordon DJ

Fri Oct 20 00:00:00 UTC 2017

Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Yu H,Zhang X,Liu R,Li H,Xiao X,Zhou Y,Wei C,Yang M,Liao M,Zhao J,Xia Z,Liao Q

Sat Jul 01 00:00:00 UTC 2017

Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Yu H,Zhang X,Liu R,Li H,Xiao X,Zhou Y,Wei C,Yang M,Liao M,Zhao J,Xia Z,Liao Q

Sat Jul 01 00:00:00 UTC 2017

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.

Open biology

Ma P,Ren B,Yang X,Sun B,Liu X,Kong Q,Li C,Mao B

Tue Aug 01 00:00:00 UTC 2017

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.

Open biology

Ma P,Ren B,Yang X,Sun B,Liu X,Kong Q,Li C,Mao B

Tue Aug 01 00:00:00 UTC 2017

Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.

Nature communications

Liu G,Zhou L,Zhang H,Chen R,Zhang Y,Li L,Lu JY,Jiang H,Liu D,Qi S,Jiang YM,Yin K,Xie Z,Shi Y,Liu Y,Cao X,Chen YX,Zou D,Zhang WJ

Wed Mar 22 00:00:00 UTC 2017

Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.

Nature communications

Liu G,Zhou L,Zhang H,Chen R,Zhang Y,Li L,Lu JY,Jiang H,Liu D,Qi S,Jiang YM,Yin K,Xie Z,Shi Y,Liu Y,Cao X,Chen YX,Zou D,Zhang WJ

Wed Mar 22 00:00:00 UTC 2017

A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis.

eLife

Wang Z,Xia X,Yang X,Zhang X,Liu Y,Wu D,Fang Y,Liu Y,Xu J,Qiu Y,Zhou X

Tue Dec 12 00:00:00 UTC 2017

A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis.

eLife

Wang Z,Xia X,Yang X,Zhang X,Liu Y,Wu D,Fang Y,Liu Y,Xu J,Qiu Y,Zhou X

Tue Dec 12 00:00:00 UTC 2017

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.

Nature chemical biology

Theodoropoulos PC,Gonzales SS,Winterton SE,Rodriguez-Navas C,McKnight JS,Morlock LK,Hanson JM,Cross B,Owen AE,Duan Y,Moreno JR,Lemoff A,Mirzaei H,Posner BA,Williams NS,Ready JM,Nijhawan D

Fri Apr 01 00:00:00 UTC 2016

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.

Nature chemical biology

Theodoropoulos PC,Gonzales SS,Winterton SE,Rodriguez-Navas C,McKnight JS,Morlock LK,Hanson JM,Cross B,Owen AE,Duan Y,Moreno JR,Lemoff A,Mirzaei H,Posner BA,Williams NS,Ready JM,Nijhawan D

Fri Apr 01 00:00:00 UTC 2016

Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.

Proceedings of the National Academy of Sciences of the United States of America

Mukhopadhyay C,Triplett A,Bargar T,Heckman C,Wagner KU,Naramura M

Tue Dec 20 00:00:00 UTC 2016

Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.

Proceedings of the National Academy of Sciences of the United States of America

Mukhopadhyay C,Triplett A,Bargar T,Heckman C,Wagner KU,Naramura M

Tue Dec 20 00:00:00 UTC 2016

State estimation and prediction using clustered particle filters.

Proceedings of the National Academy of Sciences of the United States of America

Lee Y,Majda AJ

Tue Dec 20 00:00:00 UTC 2016

State estimation and prediction using clustered particle filters.

Proceedings of the National Academy of Sciences of the United States of America

Lee Y,Majda AJ

Tue Dec 20 00:00:00 UTC 2016

Suberoylanilide hydroxamic acid represses glioma stem-like cells.

Journal of biomedical science

Hsu CC,Chang WC,Hsu TI,Liu JJ,Yeh SH,Wang JY,Liou JP,Ko CY,Chang KY,Chuang JY

Fri Nov 18 00:00:00 UTC 2016

Suberoylanilide hydroxamic acid represses glioma stem-like cells.

Journal of biomedical science

Hsu CC,Chang WC,Hsu TI,Liu JJ,Yeh SH,Wang JY,Liou JP,Ko CY,Chang KY,Chuang JY

Fri Nov 18 00:00:00 UTC 2016

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.

PLoS pathogens

El Najjar F,Cifuentes-Muñoz N,Chen J,Zhu H,Buchholz UJ,Moncman CL,Dutch RE

Thu Sep 01 00:00:00 UTC 2016

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.

PLoS pathogens

El Najjar F,Cifuentes-Muñoz N,Chen J,Zhu H,Buchholz UJ,Moncman CL,Dutch RE

Thu Sep 01 00:00:00 UTC 2016

Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.

PLoS pathogens

Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H

Fri Jul 01 00:00:00 UTC 2016

Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.

PLoS pathogens

Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H

Fri Jul 01 00:00:00 UTC 2016

Insulin deficiency induces rat renal mesangial cell dysfunction via activation of IGF-1/IGF-1R pathway.

Acta pharmacologica Sinica

Kong YL,Shen Y,Ni J,Shao DC,Miao NJ,Xu JL,Zhou L,Xue H,Zhang W,Wang XX,Lu LM

Mon Feb 01 00:00:00 UTC 2016

Insulin deficiency induces rat renal mesangial cell dysfunction via activation of IGF-1/IGF-1R pathway.

Acta pharmacologica Sinica

Kong YL,Shen Y,Ni J,Shao DC,Miao NJ,Xu JL,Zhou L,Xue H,Zhang W,Wang XX,Lu LM

Mon Feb 01 00:00:00 UTC 2016

ERK-mediated NF-κB activation through ASIC1 in response to acidosis.

Oncogenesis

Chen B,Liu J,Ho TT,Ding X,Mo YY

Mon Dec 12 00:00:00 UTC 2016

ERK-mediated NF-κB activation through ASIC1 in response to acidosis.

Oncogenesis

Chen B,Liu J,Ho TT,Ding X,Mo YY

Mon Dec 12 00:00:00 UTC 2016

Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.

World journal of gastroenterology

Li Y,Liu YH,Hu YY,Chen L,Li JM

Fri Oct 14 00:00:00 UTC 2016

Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.

World journal of gastroenterology

Li Y,Liu YH,Hu YY,Chen L,Li JM

Fri Oct 14 00:00:00 UTC 2016

Influence of miR-30b regulating humoral immune response by genetic difference.

Immunologic research

Duan ZQ,Shi JD,Wu MN,Hu NZ,Hu YZ

Mon Feb 01 00:00:00 UTC 2016

Influence of miR-30b regulating humoral immune response by genetic difference.

Immunologic research

Duan ZQ,Shi JD,Wu MN,Hu NZ,Hu YZ

Mon Feb 01 00:00:00 UTC 2016

A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Tsai MH,Kuo PW,Myers CT,Li SW,Lin WC,Fu TY,Chang HY,Mefford HC,Chang YC,Tsai JW

Thu Sep 01 00:00:00 UTC 2016

A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Tsai MH,Kuo PW,Myers CT,Li SW,Lin WC,Fu TY,Chang HY,Mefford HC,Chang YC,Tsai JW

Thu Sep 01 00:00:00 UTC 2016

Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.

Biochemical and biophysical research communications

Qian G,Ren Y,Zuo Y,Yuan Y,Zhao P,Wang X,Cheng Q,Liu J,Zhang L,Guo T,Liu C,Zheng H

Fri Jun 03 00:00:00 UTC 2016

Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.

Biochemical and biophysical research communications

Qian G,Ren Y,Zuo Y,Yuan Y,Zhao P,Wang X,Cheng Q,Liu J,Zhang L,Guo T,Liu C,Zheng H

Fri Jun 03 00:00:00 UTC 2016

Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.

The Journal of biological chemistry

Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H

Fri Nov 25 00:00:00 UTC 2016

Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.

The Journal of biological chemistry

Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H

Fri Nov 25 00:00:00 UTC 2016

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.

Oncotarget

Fritsch J,Fickers R,Klawitter J,Särchen V,Zingler P,Adam D,Janssen O,Krause E,Schütze S

Tue Nov 15 00:00:00 UTC 2016

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.

Oncotarget

Fritsch J,Fickers R,Klawitter J,Särchen V,Zingler P,Adam D,Janssen O,Krause E,Schütze S

Tue Nov 15 00:00:00 UTC 2016

Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.

Journal of biomolecular screening

Wang B,Sun J,Shi J,Guo Q,Tong X,Zhang J,Hu N,Hu Y

Fri Jul 01 00:00:00 UTC 2016

Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.

Journal of biomolecular screening

Wang B,Sun J,Shi J,Guo Q,Tong X,Zhang J,Hu N,Hu Y

Fri Jul 01 00:00:00 UTC 2016

Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.

Molecular brain

Park C,Lee SA,Hong JH,Suh Y,Park SJ,Suh BK,Woo Y,Choi J,Huh JW,Kim YM,Park SK

Sat Jul 02 00:00:00 UTC 2016

Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.

Molecular brain

Park C,Lee SA,Hong JH,Suh Y,Park SJ,Suh BK,Woo Y,Choi J,Huh JW,Kim YM,Park SK

Sat Jul 02 00:00:00 UTC 2016

SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.

Nucleic acids research

Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J

Fri Sep 18 00:00:00 UTC 2015

SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.

Nucleic acids research

Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J

Fri Sep 18 00:00:00 UTC 2015

SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.

Nucleic acids research

Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J

Fri Sep 18 00:00:00 UTC 2015

Drosophila Dicer-2 has an RNA interference-independent function that modulates Toll immune signaling.

Science advances

Wang Z,Wu D,Liu Y,Xia X,Gong W,Qiu Y,Yang J,Zheng Y,Li J,Wang YF,Xiang Y,Hu Y,Zhou X

Thu Oct 01 00:00:00 UTC 2015

Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.

Journal of virology

Xie M,Xuan B,Shan J,Pan D,Sun Y,Shan Z,Zhang J,Yu D,Li B,Qian Z

Sun Mar 01 00:00:00 UTC 2015

Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.

Journal of virology

Xie M,Xuan B,Shan J,Pan D,Sun Y,Shan Z,Zhang J,Yu D,Li B,Qian Z

Sun Mar 01 00:00:00 UTC 2015

Finding Missing Proteins from the Epigenetically Manipulated Human Cell with Stringent Quality Criteria.

Journal of proteome research

Yang L,Lian X,Zhang W,Guo J,Wang Q,Li Y,Chen Y,Yin X,Yang P,Lan F,He QY,Zhang G,Wang T

Fri Sep 04 00:00:00 UTC 2015

Finding Missing Proteins from the Epigenetically Manipulated Human Cell with Stringent Quality Criteria.

Journal of proteome research

Yang L,Lian X,Zhang W,Guo J,Wang Q,Li Y,Chen Y,Yin X,Yang P,Lan F,He QY,Zhang G,Wang T

Fri Sep 04 00:00:00 UTC 2015

Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates.

Neurobiology of aging

Luccarini I,Grossi C,Rigacci S,Coppi E,Pugliese AM,Pantano D,la Marca G,Ed Dami T,Berti A,Stefani M,Casamenti F

Sun Feb 01 00:00:00 UTC 2015

Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates.

Neurobiology of aging

Luccarini I,Grossi C,Rigacci S,Coppi E,Pugliese AM,Pantano D,la Marca G,Ed Dami T,Berti A,Stefani M,Casamenti F

Sun Feb 01 00:00:00 UTC 2015

Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats.

Molecular and cellular endocrinology

Li D,Wang X,Lan X,Li Y,Liu L,Yi J,Li J,Sun Q,Wang Y,Li H,Zhong N,Holmdahl R,Lu S

Sun Feb 15 00:00:00 UTC 2015

Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats.

Molecular and cellular endocrinology

Li D,Wang X,Lan X,Li Y,Liu L,Yi J,Li J,Sun Q,Wang Y,Li H,Zhong N,Holmdahl R,Lu S

Sun Feb 15 00:00:00 UTC 2015

Analysis of grayscale characteristics in images of labeled microtubules from cultured cardiac myocytes.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

Dang Y,Lan X,Zhang Q,Li L,Huang Y

Wed Apr 01 00:00:00 UTC 2015

Analysis of grayscale characteristics in images of labeled microtubules from cultured cardiac myocytes.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

Dang Y,Lan X,Zhang Q,Li L,Huang Y

Wed Apr 01 00:00:00 UTC 2015

Cell expression patterns of CD147 in N-diethylnitrosamine/phenobarbital-induced mouse hepatocellular carcinoma.

Journal of molecular histology

Lu M,Wu J,He F,Wang XL,Li C,Chen ZN,Bian H

Sun Feb 01 00:00:00 UTC 2015

Cell expression patterns of CD147 in N-diethylnitrosamine/phenobarbital-induced mouse hepatocellular carcinoma.

Journal of molecular histology

Lu M,Wu J,He F,Wang XL,Li C,Chen ZN,Bian H

Sun Feb 01 00:00:00 UTC 2015

Increased stathmin expression strengthens fear conditioning in epileptic rats.

Biomedical reports

Zhang L,Feng D,Tao H,DE X,Chang Q,Hu Q

Thu Jan 01 00:00:00 UTC 2015

Increased stathmin expression strengthens fear conditioning in epileptic rats.

Biomedical reports

Zhang L,Feng D,Tao H,DE X,Chang Q,Hu Q

Thu Jan 01 00:00:00 UTC 2015

Modulation of amylose content by structure-based modification of OsGBSS1 activity in rice (Oryza sativa L.).

Plant biotechnology journal

Liu D,Wang W,Cai X

Mon Dec 01 00:00:00 UTC 2014

Modulation of amylose content by structure-based modification of OsGBSS1 activity in rice (Oryza sativa L.).

Plant biotechnology journal

Liu D,Wang W,Cai X

Mon Dec 01 00:00:00 UTC 2014

lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.

The FEBS journal

Zhu M,Chen Q,Liu X,Sun Q,Zhao X,Deng R,Wang Y,Huang J,Xu M,Yan J,Yu J

Fri Aug 01 00:00:00 UTC 2014

lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.

The FEBS journal

Zhu M,Chen Q,Liu X,Sun Q,Zhao X,Deng R,Wang Y,Huang J,Xu M,Yan J,Yu J

Fri Aug 01 00:00:00 UTC 2014

Axl receptor tyrosine kinase expression in breast cancer.

Journal of clinical pathology

D'Alfonso TM,Hannah J,Chen Z,Liu Y,Zhou P,Shin SJ

Fri Aug 01 00:00:00 UTC 2014

Axl receptor tyrosine kinase expression in breast cancer.

Journal of clinical pathology

D'Alfonso TM,Hannah J,Chen Z,Liu Y,Zhou P,Shin SJ

Fri Aug 01 00:00:00 UTC 2014

TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer.

Oncotarget

Li X,Liu Y,Chen W,Fang Y,Xu H,Zhu HH,Chu M,Li W,Zhuang G,Gao WQ

Wed Oct 15 00:00:00 UTC 2014

TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer.

Oncotarget

Li X,Liu Y,Chen W,Fang Y,Xu H,Zhu HH,Chu M,Li W,Zhuang G,Gao WQ

Wed Oct 15 00:00:00 UTC 2014

INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.

Molecular and cellular biochemistry

Yunlei Z,Zhe C,Yan L,Pengcheng W,Yanbo Z,Le S,Qianjin L

Fri Feb 01 00:00:00 UTC 2013

INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.

Molecular and cellular biochemistry

Yunlei Z,Zhe C,Yan L,Pengcheng W,Yanbo Z,Le S,Qianjin L

Fri Feb 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: alpha tubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3E; Alpha-tubulin 4; Alpha-tubulin 6; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; Alpha-tubulin isotype M-alpha-6; Alpha-tubulin ubiquitous; beta-tubulin T beta15 (aa 1-445); class II beta-tubulin isotype; class IIb beta-tubulin; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; T beta-15; Talpha1 alpha-tubulin; Testis-specific alpha-tubulin; TUBA1/3/4; Tubulin alpha; Tubulin alpha chain-like 3; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-1B chain; Tubulin alpha-1C chain; Tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; Tubulin alpha-3E chain; Tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-6 chain; Tubulin alpha-ubiquitous chain; Tubulin B-alpha-1; Tubulin beta-2B chain; Tubulin H2-alpha; Tubulin K-alpha-1; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin, alpha-like 3; tubulin, beta 2; tubulin, beta 2B class IIb; tubulin, beta polypeptide paralog

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Gene Aliases: 2410129E14Rik; ALS22; B-ALPHA-1; bA408E5.3; bA506K6.1; bcm948; brdp; H2-ALPHA; K-ALPHA-1; LIS3; M[a]4; M[a]6; PMGYSA; RGD1309427; RGD1565476; Tuba-1; TUBA1; TUBA1A; TUBA1B; TUBA1C; TUBA2; TUBA3; TUBA3C; TUBA3E; Tuba4; TUBA4A; TUBA6; TUBAL3; Tubb2; Tubb2a; TUBB2B

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Function(s)

GTPase activity structural molecule activity structural constituent of cytoskeleton protein binding GTP binding protein domain specific binding double-stranded RNA binding ubiquitin protein ligase binding molecular_function enzyme binding nucleotide binding protein heterodimerization activity

Process(es)

microtubule-based process protein polymerization cellular response to interleukin-4 neuron migration cytoskeleton organization cytoskeleton-dependent intracellular transport cell division metabolic process biological_process G2/M transition of mitotic cell cycle platelet degranulation microtubule cytoskeleton organization

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alpha Tubulin Monoclonal Antibody (1E4C11)

alpha Tubulin Antibody (66031-1-IG) in ICC/IF

Product Details

66031-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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