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Product Details
PA1-86602
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified porcine brain tubulin.
Conjugate
Form
Liquid
Concentration
5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_935821
Product Specific Information
Rabbit anti Porcine tubulin antibody recognizes tubulin, a protein which is the major constituent of microtubules.
Target Information
Tubulin protein is the major constituent of microtubules. Tubulin is a dimer of alpha and beta chains, which binds two molecules of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. There are at least six isotypes of both alpha- and beta- tubulin in human cells, which are distinguished by slightly different amino acid sequences and encoded by a large, multigene family that has been highly conserved throughout evolution. Although the most important functions of microtubules in proliferative cells are through their actions as components of the mitotic spindle, they are also involved in many other essential functions throughout the cell cycle of both malignant and nonmalignant cells. Anti-microtubule agents including Vinca alkaloids and taxanes may disrupt many of these essential functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-tubulin 1; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; beta 5-tubulin; beta Ib tubulin; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; Talpha1 alpha-tubulin; Tubulin alpha; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-3 chain; Tubulin B-alpha-1; tubulin beta; Tubulin beta chain; Tubulin beta-1 chain; Tubulin beta-5 chain; tubulin, alpha 1; tubulin, alpha 1a; tubulin, alpha, brain-specific; tubulin, beta 1 class VI; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; α/β-tubulin
Gene Aliases: 2810484G07Rik; B-ALPHA-1; CDCBM6; CH242-247L10.4; CSCSC1; LIS3; M(beta)1; M40; OK/SW-cl.56; Tuba-1; Tuba1; TUBA1A; TUBA3; TUBB; TUBB1; TUBB5
UniProt ID: (Human) Q71U36, (Human) P07437, (Human) Q9H4B7, (Pig) Q767L7, (Mouse) P68369, (Rat) P68370, (Mouse) A2AQ07
Entrez Gene ID: (Human) 7846, (Human) 203068, (Pig) 100134983, (Human) 81027, (Pig) 733686, (Mouse) 22142, (Rat) 64158, (Mouse) 545486, (Rat) 679312
GTPase activity
structural molecule activity
structural constituent of cytoskeleton
protein binding
GTP binding
protein domain specific binding
ubiquitin protein ligase binding
protein complex binding
GTPase activating protein binding
MHC class I protein binding
nucleotide binding
protein heterodimerization activity
microtubule-based process
protein polymerization
spindle assembly
G2/M transition of mitotic cell cycle
movement of cell or subcellular component
cellular process
cytoskeleton-dependent intracellular transport
natural killer cell mediated cytotoxicity
cell division
metabolic process
cytoskeleton organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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