Product References
Age-related metabolic and neurodegenerative changes in SAMP8 mice.
Aging
Pačesová A,Holubová M,Hrubá L,Strnadová V,Neprašová B,Pelantová H,Kuzma M,Železná B,Kuneš J,Maletínská L
71-5800 was used in Immunohistochemistry to conclude that changes specific for neurodegenerative processes were observed between the 3rd and 6th month of age in SAMP8 mice; thus, potential neuroprotective interventions could be applied between these ages.
Fri Sep 16 00:00:00 UTC 2022
No difference in cerebral perfusion between the wild-type and the 5XFAD mouse model of Alzheimer's disease.
Scientific reports
DeBay DR,Phi TT,Bowen CV,Burrell SC,Darvesh S
71-5800 was used in Immunohistochemistry to suggest apparent discrepancies in rCBF between human AD and the 5XFAD model.
Thu Dec 22 00:00:00 UTC 2022
5xFAD mice do not have myenteric amyloidosis, dysregulation of neuromuscular transmission or gastrointestinal dysmotility.
Neurogastroenterology and motility
Yelleswarapu NK,Masino M,Henderson S,Fernandes R,Swain G,Galligan JJ,Xu H
71-5800 was used in Immunohistochemistry to show that changes in the gut microbiome and inflammatory markers can contribute to AD development in the central nervous system (CNS).
Thu Dec 01 00:00:00 UTC 2022
Europium-Doped Cerium Oxide Nanoparticles for Microglial Amyloid Beta Clearance and Homeostasis.
ACS chemical neuroscience
Machhi J,Yeapuri P,Markovic M,Patel M,Yan W,Lu Y,Cohen JD,Hasan M,Abdelmoaty MM,Zhou Y,Xiong H,Wang X,Mosley RL,Gendelman HE,Kevadiya BD
71-5800 was used in ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry to generate cellular immune homeostasis in AD models.
Wed Apr 20 00:00:00 UTC 2022
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner.
Journal of neuroinflammation
Gannon OJ,Robison LS,Salinero AE,Abi-Ghanem C,Mansour FM,Kelly RD,Tyagi A,Brawley RR,Ogg JD,Zuloaga KL
71-5800 was used in Immunohistochemistry-immunofluorescence to indicate that High-fat diet had a wider array of metabolic, cognitive, and neuropathological consequences in AD and MxD females compared to males.
Sat May 14 00:00:00 UTC 2022
Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models.
Cell reports
Rangan P,Lobo F,Parrella E,Rochette N,Morselli M,Stephen TL,Cremonini AL,Tagliafico L,Persia A,Caffa I,Monacelli F,Odetti P,Bonfiglio T,Nencioni A,Pigliautile M,Boccardi V,Mecocci P,Pike CJ,Cohen P,LaDu MJ,Pellegrini M,Xia K,Tran K,Ann B,Chowdhury D,Longo VD
71-5800 was used in Immunohistochemistry to show that fasting-mimicking diet cycles reduce cognitive decline and Alzheimer's disease (AD) pathology in E4FAD and 3xTg AD mouse models, with effects superior to those caused by protein restriction cycles.
Tue Sep 27 00:00:00 UTC 2022
A positive allosteric modulator for the muscarinic receptor (M1 mAChR) improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice.
British journal of pharmacology
Abd-Elrahman KS,Sarasija S,Colson TL,Ferguson SSG
71-5800 was used in Western Blotting to study how using the the M1 muscarinic ACh receptor (M1 mAChR) positive allosteric modulators (PAMs) could be a viable disease-modifying approach that should be exploited clinically to slow Alzheimer's disease (AD) in women.
Fri Apr 01 00:00:00 UTC 2022
Microglial transcription profiles in mouse and human are driven by APOE4 and sex.
iScience
Moser VA,Workman MJ,Hurwitz SJ,Lipman RM,Pike CJ,Svendsen CN
Published figure using beta Amyloid polyclonal antibody (Product # 71-5800) in Immunohistochemistry
Fri Nov 19 00:00:00 UTC 2021
Restoring activity in the thalamic reticular nucleus improves sleep architecture and reduces Aβ accumulation in mice.
Science translational medicine
Jagirdar R,Fu CH,Park J,Corbett BF,Seibt FM,Beierlein M,Chin J
71-5800 was used in Immunohistochemistry to study how the thalamic reticular nucleus (TRN) may play a major role in symptoms associated with Alzheimer's disease.
Wed Nov 03 00:00:00 UTC 2021
CD4+ effector T cells accelerate Alzheimer's disease in mice.
Journal of neuroinflammation
Machhi J,Yeapuri P,Lu Y,Foster E,Chikhale R,Herskovitz J,Namminga KL,Olson KE,Abdelmoaty MM,Gao J,Quadros RM,Kiyota T,Jingjing L,Kevadiya BD,Wang X,Liu Y,Poluektova LY,Gurumurthy CB,Mosley RL,Gendelman HE
71-5800 was used in Immunohistochemistry to investigate the role of effector immunity and how it could affect cellular-level disease pathobiology in an alzheimer's disease animal model.
Fri Nov 19 00:00:00 UTC 2021
Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aβ1-42-mediated toxicity.
Neurobiology of disease
Tripathy D,Migazzi A,Costa F,Roncador A,Gatto P,Fusco F,Boeri L,Albani D,Juárez-Hernández JL,Musio C,Colombo L,Salmona M,Wilhelmus MMM,Drukarch B,Pennuto M,Basso M
71-5800 was used in Immunohistochemistry to investigate if a precision medicine pipeline that integrates high-throughput chemical screens with matched patient-derived cell lines and patient-derived xenografts (PDX) helps to identify new treatments for colorectal cancer.
Wed Jul 01 00:00:00 UTC 2020
Aging Reduces Estradiol Protection Against Neural but Not Metabolic Effects of Obesity in Female 3xTg-AD Mice.
Frontiers in aging neuroscience
Christensen A,Liu J,Pike CJ
71-5800 was used in Immunohistochemistry to compare how treatment with the primary estrogen, 17β-estradiol (E2), affects levels of Alzheimer''s disease-like neuropathology, behavioral impairment, and other neural and systemic effects of preexisting diet-induced obesity in female 3xTg-AD mice.
Thu Mar 28 00:00:00 UTC 2024
Aging Reduces Estradiol Protection Against Neural but Not Metabolic Effects of Obesity in Female 3xTg-AD Mice.
Frontiers in aging neuroscience
Christensen A,Liu J,Pike CJ
71-5800 was used in Immunohistochemistry to compare how treatment with the primary estrogen, 17β-estradiol (E2), affects levels of Alzheimer''s disease-like neuropathology, behavioral impairment, and other neural and systemic effects of preexisting diet-induced obesity in female 3xTg-AD mice.
Thu Mar 28 00:00:00 UTC 2024
Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived β-amyloid.
FEBS open bio
Balczon R,Morrow KA,Leavesley S,Francis CM,Stevens TC,Agwaramgbo E,Williams C,Stevens RP,Langham G,Voth S,Cioffi EA,Weintraub SE,Stevens T
Published figure using beta Amyloid polyclonal antibody (Product # 71-5800) in Neutralization
Sun Nov 01 00:00:00 UTC 2020
Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived β-amyloid.
FEBS open bio
Balczon R,Morrow KA,Leavesley S,Francis CM,Stevens TC,Agwaramgbo E,Williams C,Stevens RP,Langham G,Voth S,Cioffi EA,Weintraub SE,Stevens T
Published figure using beta Amyloid polyclonal antibody (Product # 71-5800) in Neutralization
Sun Nov 01 00:00:00 UTC 2020
mGluR5 Contribution to Neuropathology in Alzheimer Mice Is Disease Stage-Dependent.
ACS pharmacology & translational science
Abd-Elrahman KS,Hamilton A,Albaker A,Ferguson SSG
71-5800 was used in Western Blot to indicate that the contribution of pathological mGluR5-signaling to Alzheimer's disease (AD) may shift as the disease progresses.
Fri Apr 10 00:00:00 UTC 2020
Staining and Quantification of β-Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease.
Methods in molecular biology (Clifton, N.J.)
Christensen A,Pike CJ
71-5800 was used in Immunohistochemistry to describe two techniques for the histological detection of Aβ, immunostaining with Aβ antibodies and staining with the amyloid dye thioflavin S, and its quantification using digital imaging.
Fri Mar 12 00:00:00 UTC 2021
APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Christensen A,Pike CJ
71-5800 was used in Immunohistochemistry to demonstrate a gene-environment interaction between APOE and obesogenic diets in females.
Fri Mar 01 00:00:00 UTC 2019
Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.
The American journal of pathology
Chiang ACA,Fowler SW,Reddy R,Pletnikova O,Troncoso JC,Sherman MA,Lesne SE,Jankowsky JL
71-5800 was used in Immunohistochemistry to quantify amyloid-Β oligomers during the evolution of cognitive deficits in an aggressive model of amyloid-Β amyloidosis.
Thu Mar 01 00:00:00 UTC 2018
URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer's disease.
Journal of neuroinflammation
Kiyota T,Machhi J,Lu Y,Dyavarshetty B,Nemati M,Zhang G,Mosley RL,Gelbard HA,Gendelman HE
71-5800 was used in Immunohistochemistry to study how URMC-099 promotes endolysosomal protein trafficking and reduces amyloid-beta (AΒ) microglial pro-inflammatory activities, and assess whether these responses affect AΒ pathobiogenesis.
Sat May 05 00:00:00 UTC 2018
Quantification of Butyrylcholinesterase Activity as a Sensitive and Specific Biomarker of Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Macdonald IR,Maxwell SP,Reid GA,Cash MK,DeBay DR,Darvesh S
71-5800 was used in Immunohistochemistry to highlight the predictive value of butyrylcholinesterase as a biomarker for Alzheimer's disease.
Fri Mar 16 00:00:00 UTC 2018
Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice.
eNeuro
Moser VA,Pike CJ
Published figure using beta Amyloid polyclonal antibody (Product # 71-5800) in Immunohistochemistry
Wed Mar 28 00:00:00 UTC 2018
Cholinesterases in normal and Alzheimer's disease primary olfactory gyrus.
Neuropathology and applied neurobiology
Hamodat H,Cash MK,Fisk JD,Darvesh S
71-5800 was used in Immunohistochemistry to examine the anatomical and cholinergic organization of the POG in normal human brain and neuropathology in AD.
Fri Dec 01 00:00:00 UTC 2017
Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice.
PloS one
Christensen A,Pike CJ
71-5800 was used in Immunohistochemistry to assess whether oestrogen-based hormone therapy for Alzheimer's disease is only beneficial if initiated near the onset of menopause.
Mon Oct 09 00:00:00 UTC 2017
The blood clotting Factor XIIIa forms unique complexes with amyloid-beta (Aβ) and colocalizes with deposited Aβ in cerebral amyloid angiopathy.
Neuropathology and applied neurobiology
de Jager M,Boot MV,Bol JG,Brevé JJ,Jongenelen CA,Drukarch B,Wilhelmus MM
Published figure using beta Amyloid polyclonal antibody (Product # 71-5800) in Immunofluorescence
Fri Apr 01 00:00:00 UTC 2016
Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer's disease mouse models.
Scientific reports
Wilhelmus MM,de Jager M,Smit AB,van der Loo RJ,Drukarch B
71-5800 was used in immunohistochemistry - frozen section to study colocalization of A-beta pathology in Alzheimer's disease mouse models with catalytically active tissue transglutaminase
Wed Feb 03 00:00:00 UTC 2016
Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer's disease mouse models.
Scientific reports
Wilhelmus MM,de Jager M,Smit AB,van der Loo RJ,Drukarch B
71-5800 was used in immunohistochemistry - frozen section to study colocalization of A-beta pathology in Alzheimer's disease mouse models with catalytically active tissue transglutaminase
Wed Feb 03 00:00:00 UTC 2016
Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity.
Journal of neurochemistry
de Jager M,Drukarch B,Hofstee M,Brevé J,Jongenelen CA,Bol JG,Wilhelmus MM
71-5800 was used in immunohistochemistry to study the role of apolipoprotein E in cerebral amyloid angiopathy.
Tue Sep 01 00:00:00 UTC 2015
Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse model.
Neuroscience
Reid GA,Darvesh S
71-5800 was used in immunohistochemistry to investigate butyrylcholinesterase activity in a mouse model of Alzheimer's disease.
Thu Jul 09 00:00:00 UTC 2015
Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice.
Behavioural brain research
McClean PL,Jalewa J,Hölscher C
71-5800 was used in immunohistochemistry to demonstrate that liraglutide has prophylactic properties in Alzheimer's disease models.
Thu Oct 15 00:00:00 UTC 2015
Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fowler SW,Chiang AC,Savjani RR,Larson ME,Sherman MA,Schuler DR,Cirrito JR,Lesné SE,Jankowsky JL
71-5800 was used in immunohistochemistry - frozen section to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure
Wed Jun 04 00:00:00 UTC 2014
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease.
Neuropharmacology
McClean PL,Hölscher C
71-5800 was used in immunohistochemistry (frozen) to demonstrate that GLP-1 receptor agonists are therapeutic for Alzheimer's disease.
Sat Nov 01 00:00:00 UTC 2014
Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease.
Neuropharmacology
McClean PL,Hölscher C
71-5800 was used in immunohistochemistry - frozen section to test if Liraglutide has restorative effects in late-stage Alzheimer's disease in mice.
Wed Jan 01 00:00:00 UTC 2014
Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Molecular and cellular neurosciences
Hohsfield LA,Daschil N,Orädd G,Strömberg I,Humpel C
71-5800 was used in immunohistochemistry to investigate hypercholesterolemia at various stages of Alzheimer's disease
Sat Nov 01 00:00:00 UTC 2014
Early detection of cerebral glucose uptake changes in the 5XFAD mouse.
Current Alzheimer research
Macdonald IR,DeBay DR,Reid GA,O'Leary TP,Jollymore CT,Mawko G,Burrell S,Martin E,Bowen CV,Brown RE,Darvesh S
71-5800 was used in immunohistochemistry - frozen section to examine brain beta-amyloid plaque deposition and glucose uptake in a mouse model of Alzheimer's disease
Mon Feb 02 00:00:00 UTC 2015
Early detection of cerebral glucose uptake changes in the 5XFAD mouse.
Current Alzheimer research
Macdonald IR,DeBay DR,Reid GA,O'Leary TP,Jollymore CT,Mawko G,Burrell S,Martin E,Bowen CV,Brown RE,Darvesh S
71-5800 was used in immunohistochemistry - frozen section to examine brain beta-amyloid plaque deposition and glucose uptake in a mouse model of Alzheimer's disease
Mon Feb 02 00:00:00 UTC 2015
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model.
Aging cell
Parrella E,Maxim T,Maialetti F,Zhang L,Wan J,Wei M,Cohen P,Fontana L,Longo VD
71-5800 was used in Immunohistochemistry to show that periodic protein restriction cycles without CR can promote changes in circulating growth factors and tau phosphorylation associated with protection against age-related neuropathologies.
Mon Apr 01 00:00:00 UTC 2013
Tissue transglutaminase colocalizes with extracellular matrix proteins in cerebral amyloid angiopathy.
Neurobiology of aging
de Jager M,van der Wildt B,Schul E,Bol JG,van Duinen SG,Drukarch B,Wilhelmus MM
71-5800 was used in immunohistochemistry to determine the distribution pattern, cellular source, and activity of tissue transglutaminase in cerebral amyloid angiopathy, Alzheimer's disease, and hereditary cerebral hemorrhage with amyloidosis of the Dutch type cases.
Mon Apr 01 00:00:00 UTC 2013
D-Ala2GIP facilitated synaptic plasticity and reduces plaque load in aged wild type mice and in an Alzheimer's disease mouse model.
Journal of Alzheimer's disease : JAD
Faivre E,Hölscher C
71-5800 was used in immunohistochemistry to test if D-Ala2GIP protects mice with advanced staged Alzheimer's disease.
Thu Oct 17 00:00:00 UTC 2013
Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice.
Behavioural brain research
Laursen B,Mørk A,Plath N,Kristiansen U,Bastlund JF
71-5800 was used in ELISA to study cholinergic dysfunction in a murine model of Alzheimer's disease.
Fri Mar 01 00:00:00 UTC 2013
Neuroprotective effects of D-Ala(2)GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model.
Alzheimer's research & therapy
Faivre E,Hölscher C
71-5800 was used in immunohistochemistry to test the therapeutic value of D-Ala2GIP in a mouse model of Alzheimer's disease
Tue May 20 00:00:00 UTC 2014
A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease.
PloS one
Parthsarathy V,McClean PL,Hölscher C,Taylor M,Tinker C,Jones G,Kolosov O,Salvati E,Gregori M,Masserini M,Allsop D
71-5800 was used in immunohistochemistry - frozen section to study the use of a retro-inverso peptide inhibitor to treat a murine model of Alzheimer's disease.
Thu Aug 01 00:00:00 UTC 2013
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.
The Journal of clinical investigation
Bomfim TR,Forny-Germano L,Sathler LB,Brito-Moreira J,Houzel JC,Decker H,Silverman MA,Kazi H,Melo HM,McClean PL,Holscher C,Arnold SE,Talbot K,Klein WL,Munoz DP,Ferreira ST,De Felice FG
71-5800 was used in immunohistochemistry to investigate dysregulated insulin signaling in Alzheimer's disease and diabetes.
Sun Apr 01 00:00:00 UTC 2012
Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice.
Neurobiology of disease
Overk CR,Lu PY,Wang YT,Choi J,Shaw JW,Thatcher GR,Mufson EJ
71-5800 was used in immunohistochemistry to assess the effects of depleting both circulating and brain estrogen levels in a mouse model of Alzheimer's disease.
Sun Jan 01 00:00:00 UTC 2012
Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice.
Neurobiology of aging
Gengler S,McClean PL,McCurtin R,Gault VA,Hölscher C
71-5800 was used in immunohistochemistry - frozen section to examine the effects of Val(8)GLP-1 in a mouse model of Alzheimer's disease
Wed Feb 01 00:00:00 UTC 2012
Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice.
Brain research
Rosario ER,Carroll JC,Pike CJ
71-5800 was used in immunohistochemistry to examine how changes in testosterone and luteinizing hormone contribute to Alzheimer's disease.
Mon Jul 23 00:00:00 UTC 2012
The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.
Brain research
Hamilton A,Holscher C
71-5800 was used in immunohistochemistry - free floating to examine how ageing affects neurogenesis and oxidative stress in a mouse model of Alzheimer's disease.
Tue Apr 17 00:00:00 UTC 2012
Butyrylcholinesterase is associated with β-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease.
Journal of neuropathology and experimental neurology
Darvesh S,Cash MK,Reid GA,Martin E,Mitnitski A,Geula C
71-5800 was used in immunohistochemistry - frozen section to investigate the role of BuChE using the APPSWE/PSENdE9 transgenic mouse model.
Sun Jan 01 00:00:00 UTC 2012
Butyrylcholinesterase is associated with β-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease.
Journal of neuropathology and experimental neurology
Darvesh S,Cash MK,Reid GA,Martin E,Mitnitski A,Geula C
71-5800 was used in immunohistochemistry - frozen section to investigate the role of BuChE using the APPSWE/PSENdE9 transgenic mouse model.
Sun Jan 01 00:00:00 UTC 2012
Effects of NK-4 in a transgenic mouse model of Alzheimer's disease.
PloS one
Ohta H,Arai S,Akita K,Ohta T,Fukuda S
71-5800 was used in immunohistochemistry - paraffin section to report the effects of NK-4 on the toxicity of Aβ, on cognitive function, and Aβ concentration in a mouse model of Alzheimer's disease.
Mon May 14 00:00:00 UTC 2012
Effects of NK-4 in a transgenic mouse model of Alzheimer's disease.
PloS one
Ohta H,Arai S,Akita K,Ohta T,Fukuda S
71-5800 was used in immunohistochemistry - paraffin section to report the effects of NK-4 on the toxicity of Aβ, on cognitive function, and Aβ concentration in a mouse model of Alzheimer's disease.
Mon May 14 00:00:00 UTC 2012
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
McClean PL,Parthsarathy V,Faivre E,Hölscher C
71-5800 was used in immunohistochemistry - frozen section to examine the effects of peripherally injected liraglutide in an Alzheimer mouse model.
Wed Apr 27 00:00:00 UTC 2011
Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice.
Endocrinology
Carroll JC,Rosario ER,Villamagna A,Pike CJ
71-5800 was used in Immunohistochemistry to provide new insight into the neural interactions between estradiol and progesterone that may prove valuable in optimising hormone therapy regimens in postmenopausal women.
Tue Jun 01 00:00:00 UTC 2010
Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Neuroscience
Mei X,Ezan P,Giaume C,Koulakoff A
71-5800 was used in immunohistochemistry to determine the expression pattern of connexin43 and 30 in two murine models of Alzheimer disease
Wed Nov 24 00:00:00 UTC 2010
Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure.
Brain research
Carroll JC,Rosario ER,Kreimer S,Villamagna A,Gentzschein E,Stanczyk FZ,Pike CJ
71-5800 was used in immunohistochemistry to explore the effects of sex steroid hormones in a mouse model of Alzheimer's disease
Fri Dec 17 00:00:00 UTC 2010
Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure.
Brain research
Carroll JC,Rosario ER,Kreimer S,Villamagna A,Gentzschein E,Stanczyk FZ,Pike CJ
71-5800 was used in immunohistochemistry to explore the effects of sex steroid hormones in a mouse model of Alzheimer's disease
Fri Dec 17 00:00:00 UTC 2010
Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice.
PloS one
Gengler S,Hamilton A,Hölscher C
71-5800 was used in immunohistochemistry to study synaptic plasticity in area CA1 in a novel Alzheimer disease mouse model
Mon Mar 22 00:00:00 UTC 2010
Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice.
PloS one
Gengler S,Hamilton A,Hölscher C
71-5800 was used in immunohistochemistry to study synaptic plasticity in area CA1 in a novel Alzheimer disease mouse model
Mon Mar 22 00:00:00 UTC 2010
Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice.
Endocrinology
Carroll JC,Pike CJ
71-5800 was used in immunohistochemistry to assess the use of selective estrogen receptor modulators using a murine model of Alzheimer's disease.
Thu May 01 00:00:00 UTC 2008
Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.
PloS one
Xu G,Karch C,Li N,Lin N,Fromholt D,Gonzales V,Borchelt DR
71-5800 was used in western blot to discuss proteins that regulate the metabolism of the amyloid precursor protein and beta-amyloid peptides
Mon Sep 08 00:00:00 UTC 2008
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Carroll JC,Rosario ER,Chang L,Stanczyk FZ,Oddo S,LaFerla FM,Pike CJ
71-5800 was used in immunohistochemistry to examine the individual and combined effects of estrogen and progesterone on beta-amyloid accumulation, tau hyperphosphorylation, and hippocampal-dependent behavioral impairments
Wed Nov 28 00:00:00 UTC 2007
Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.
The Journal of biological chemistry
Jankowsky JL,Younkin LH,Gonzales V,Fadale DJ,Slunt HH,Lester HA,Younkin SG,Borchelt DR
71-5800 was used in immunohistochemistry - paraffin section, immunoprecipitation, and western blot to explore the amyloidogenic potential of mouse A beta
Fri Aug 03 00:00:00 UTC 2007
Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.
The Journal of biological chemistry
Jankowsky JL,Younkin LH,Gonzales V,Fadale DJ,Slunt HH,Lester HA,Younkin SG,Borchelt DR
71-5800 was used in immunohistochemistry - paraffin section, immunoprecipitation, and western blot to explore the amyloidogenic potential of mouse A beta
Fri Aug 03 00:00:00 UTC 2007
Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.
The Journal of biological chemistry
Jankowsky JL,Younkin LH,Gonzales V,Fadale DJ,Slunt HH,Lester HA,Younkin SG,Borchelt DR
71-5800 was used in immunohistochemistry - paraffin section, immunoprecipitation, and western blot to explore the amyloidogenic potential of mouse A beta
Fri Aug 03 00:00:00 UTC 2007
Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rosario ER,Carroll JC,Oddo S,LaFerla FM,Pike CJ
71-5800 was used in immunohistochemistry - free floating to study the relationship between androgen depletion and Alzheimer's disease
Wed Dec 20 00:00:00 UTC 2006
Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rosario ER,Carroll JC,Oddo S,LaFerla FM,Pike CJ
71-5800 was used in immunohistochemistry - free floating to study the relationship between androgen depletion and Alzheimer's disease
Wed Dec 20 00:00:00 UTC 2006
Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy.
Brain : a journal of neurology
Scolding NJ,Joseph F,Kirby PA,Mazanti I,Gray F,Mikol J,Ellison D,Hilton DA,Williams TL,MacKenzie JM,Xuereb JH,Love S
71-5800 was used in immunohistochemistry - paraffin section to describe patients with Abeta-related angiitis
Tue Mar 01 00:00:00 UTC 2005
Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release.
Journal of bioenergetics and biomembranes
Aleardi AM,Benard G,Augereau O,Malgat M,Talbot JC,Mazat JP,Letellier T,Dachary-Prigent J,Solaini GC,Rossignol R
71-5800 was used in western blot to test if gradual mitochondrial dysfunction contributes to the initiation and progression of sporadic Alzheimer's disease
Mon Aug 01 00:00:00 UTC 2005
Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.
The Journal of biological chemistry
Meyer EL,Strutz N,Gahring LC,Rogers SW
71-5800 was used in western blot to investigate the processing and stability of the glutamate receptor
Fri Jun 27 00:00:00 UTC 2003
Function of beta-amyloid in cholesterol transport: a lead to neurotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yao ZX,Papadopoulos V
71-5800 was used in Western Blotting to propose that one of the physiological functions of amyloid beta-peptide (Abeta) and Abeta precursor protein is to control cholesterol transport.
Tue Oct 01 00:00:00 UTC 2002
22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide.
Journal of neurochemistry
Yao ZX,Brown RC,Teper G,Greeson J,Papadopoulos V
71-5800 was used in western blot to elucidate the mechanism of action of 22R-hydroxycholesterol on Abeta-mediated toxicity.
Sun Dec 01 00:00:00 UTC 2002
Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals.
Experimental gerontology
Weksler ME,Relkin N,Turkenich R,LaRusse S,Zhou L,Szabo P
71-5800 was used in ELISA to determine the link between lower levels of serum anti-amyloid peptide antibodies and patients with Alzheimer disease when compared to healthy elderly individuals
Mon Jul 01 00:00:00 UTC 2002
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.
Alzheimer disease and associated disorders
Xu G,Gonzales V,Borchelt DR
71-5800 was used in western blot to develop a novel method for the rapid detection of beta-amyloid aggregates in Alzheimer's patients and transgenic mouse models.
Wed Dec 04 00:00:00 UTC 2002
Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.
The Journal of biological chemistry
Mettenburg JM,Webb DJ,Gonias SL
71-5800 was used in western blot to study the mediation of the interaction with beta-amyloid peptide and growth factors due to distinct binding sites in the structure of alpha 2-macroglobulin
Fri Apr 12 00:00:00 UTC 2002
Sporadic inclusion body myositis correlates with increased expression and cross-linking by transglutaminases 1 and 2.
The Journal of biological chemistry
Choi YC,Park GT,Kim TS,Sunwoo IN,Steinert PM,Kim SY
71-5800 was used in immunohistochemistry and western blot to investigate the role of transglutaminases in sporadic inclusion body myositis
Fri Mar 24 00:00:00 UTC 2000
Amyloid-beta deposition in skeletal muscle of transgenic mice: possible model of inclusion body myopathy.
The American journal of pathology
Fukuchi K,Pham D,Hart M,Li L,Lindsey JR
71-5800 was used in immunohistochemistry - paraffin section to characterize transgenic mice that overexpress the signal plus 99-amino acid carboxyl-terminal sequences of beta protein precursor
Tue Dec 01 00:00:00 UTC 1998
