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Invitrogen
beta-Defensin 1 Polyclonal Antibody
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Product Details
PA5-94990
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1 (52-68aa FTKIQGTCYRGKAKCCK).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806796
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: COLO320 whole cell. IHC: Lung Cancer Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1
Gene Aliases: BD1; DEFB-1; DEFB1; DEFB101; HBD1
UniProt ID: (Human) P60022
Entrez Gene ID: (Human) 1672
innate immune response in mucosa
acute inflammatory response
chemotaxis
immune response
G-protein coupled receptor signaling pathway
response to bacterium
antibacterial humoral response
cAMP-mediated signaling
response to testosterone
calcium-mediated signaling using intracellular calcium source
defense response to bacterium
innate immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of sperm motility involved in capacitation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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