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DEFB126 (Defensin Beta 126) is a Protein Coding gene. Diseases associated with DEFB126 include Cervical Polyp and Infertility. Among its related pathways are Defensins and Innate Immune System. Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. The encoded protein is highly similar to an epididymal-specific secretory protein (ESP13.2) from cynomolgus monkey. Mutation of this gene is associated with impaired sperm function.
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Protein Aliases: Beta-defensin 126; Beta-defensin 26; C20orf8; DEFB-26; Defensin, Beta 126; Epididymal secretory protein 13.2; epididymal secretory protein ESP13.2; ESP13.2; HBD26
Gene Aliases: bA530N10.1; C20orf8; DEFB-26; DEFB126; DEFB26; hBD-26; HBD26
UniProt ID: (Human) Q9BYW3
Entrez Gene ID: (Human) 81623
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