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This target displays homology in the following species: Dog: 79%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 86%; Rat: 93%; Yeast: 77%
The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: crystallin, lambda 1; crystallin, lamda 1; epididymis luminal protein 30; Gul3DH; L-gulonate 3-dehydrogenase; Lambda-crystallin homolog; testicular tissue protein Li 44
Gene Aliases: CRY; CRYL1; GDH; HEL30; lambda-CRY
UniProt ID: (Human) Q9Y2S2
Entrez Gene ID: (Human) 51084
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