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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • beta Tubulin Antibodies

          Proteintech

          beta Tubulin Polyclonal Antibody

          275 References
          View all (69) beta Tubulin antibodies
          Datasheet
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          Datasheet
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          Cite beta Tubulin Polyclonal Antibody

          • Antibody Testing Data (20)
          beta Tubulin Antibody in Immunocytochemistry (ICC/IF)
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          beta Tubulin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 20

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          beta Tubulin Antibody (10068-1-AP) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed C2C12 cells using Beta Tubulin antibody (Product # 10068-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          beta Tubulin Antibody in Immunocytochemistry (ICC/IF)
          beta Tubulin Antibody in Immunocytochemistry (ICC/IF)
          beta Tubulin Antibody in Immunocytochemistry (ICC/IF)
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Western Blot (WB)
          beta Tubulin Antibody in Flow Cytometry (Flow)
          beta Tubulin Antibody in Immunoprecipitation (IP)
          beta Tubulin Antibody in Immunoprecipitation (IP)

          Product Details

          10068-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 237 publications 237 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 11 publications 11 publications

          Flow Cytometry (Flow)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication

          Miscellaneous PubMed (MISC)

          -
          View 10 publications 10 publications

          Not applicable (N/A)

          -
          View 14 publications 14 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat, Zebrafish

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          beta Tubulin Fusion Protein Ag0117 (44-259 aa encoded by BC000748)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LERISVYYN EASSHKYVPR AILVDLEPGT MDSVRSGAFG HLFRPDNFIF GQSGAGNNWA KGHYTEGAEL VDSVLDVVRK ECENCDCLQG FQLTHSLGGG TGSGMGTLLI SKVREEYPDR IMNTFSVVPS PKVSDTVVEP YNATLSIHQL VENTDETYCI DNEALYDICF RTLKLATPTY GDLNHLVSAT MSGVTTSLRF PGQLNADLRK LAVNMVP (44-259 aa encoded by BC000748)

          Target Information

          Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintenance. Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3. Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. Glutamate residues at the C-terminus of beta III tubulin can be glutamylated. The precise function of such modifications is unclear. Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression. Ser-172 phosphorylation inhibits tubulin incorporation into microtubules.Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: beta Ib tubulin; beta tubulin 1; beta-4 tubulin; beta-tubulin T beta15 (aa 1-445); betaIII-tubulin; class II beta-tubulin isotype; class IIa beta-tubulin; class IIb beta-tubulin; class III beta-tubulin; class V beta-tubulin; dJ40E16.7; dystonia 4, torsion (autosomal dominant); HSA10p15 beta-tubulin 4Q; M40 antibody; Neuron-specific class III beta-tubulin; T beta-15; tubb2a {ECO:0000250|UniProtKB:Q7TMM9}; Tubulin 5 beta; tubulin beta; Tubulin beta 8 class VIII; Tubulin beta chain; Tubulin beta class IIa; Tubulin beta class V; tubulin beta MGC4083; Tubulin beta-1 chain; Tubulin beta-2A chain; Tubulin beta-2B chain; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-4A chain; Tubulin beta-5 chain; Tubulin beta-6 chain; Tubulin beta-8 chain; Tubulin beta-III; tubulin, beta 1 class VI; tubulin, beta 2; tubulin, beta 2A class IIa; tubulin, beta 2B class IIb; tubulin, beta 3 class III; tubulin, beta 4; tubulin, beta 4 class IVa; tubulin, beta 4A class IVa; tubulin, beta 6 class V; tubulin, beta class I; tubulin, beta polypeptide; tubulin, beta polypeptide 2; tubulin, beta polypeptide paralog; tubulin, beta, 5

          View more View less

          Gene Aliases: 2310057H16Rik; 2410129E14Rik; 2810484G07Rik; 3200002H15Rik; AA408537; AI325297; AI596182; B130022C14Rik; bA506K6.1; bA631M21.2; BB220206; beta-4; beta-5; brdp; CDCBM; CDCBM1; CDCBM5; CDCBM6; CFEOM3; CFEOM3A; CSCSC1; DYT4; FEOM3; HsT1601; M(beta)1; M(beta)2; M(beta)3; M(beta)4; M(beta)5; M(beta)6; M40; OK/SW-cl.56; OOMD; OOMD2; PMGYSA; RGD1305887; RGD1309427; TUBB; TUBB-5; TUBB1; TUBB2; TUBB2A; TUBB2B; TUBB3; TUBB4; TUBB4A; TUBB5; TUBB6; TUBB8

          View more View less

          UniProt ID: (Human) P07437, (Human) Q9H4B7, (Human) Q13885, (Human) Q9BVA1, (Human) Q13509, (Human) P04350, (Human) Q9BUF5, (Human) Q3ZCM7, (Mouse) A2AQ07, (Rat) P85108, (Mouse) Q7TMM9, (Mouse) Q9CWF2, (Rat) Q3KRE8, (Mouse) Q9ERD7, (Rat) Q4QRB4, (Mouse) Q9D6F9, (Rat) P69897, (Mouse) P99024, (Mouse) Q922F4

          View more View less

          Entrez Gene ID: (Human) 203068, (Human) 81027, (Human) 7280, (Human) 347733, (Human) 10381, (Human) 10382, (Human) 84617, (Human) 347688, (Mouse) 545486, (Rat) 679312, (Rat) 498736, (Mouse) 22151, (Mouse) 73710, (Rat) 291081, (Mouse) 22152, (Rat) 246118, (Rat) 29213, (Mouse) 22153, (Rat) 29214, (Mouse) 22154, (Mouse) 67951, (Rat) 307351

          View more View less

          Function(s)
          GTPase activity structural molecule activity structural constituent of cytoskeleton protein binding GTP binding protein domain specific binding ubiquitin protein ligase binding protein complex binding GTPase activating protein binding MHC class I protein binding peptide binding molecular_function nucleotide binding
          Process(es)
          microtubule-based process metabolic process protein polymerization neuron migration G2/M transition of mitotic cell cycle movement of cell or subcellular component cellular process cytoskeleton-dependent intracellular transport natural killer cell mediated cytotoxicity spindle assembly cell division mitotic nuclear division axon guidance neuron differentiation cytoskeleton organization biological_process cell projection organization
          It has to be done as per old AB suggested Products section.
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