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Invitrogen
betacellulin Polyclonal Antibody
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betacellulin Antibody (PA5-47044) in Neu
Neutralization of betacellulin in Balb/3T3 mouse embryonic fibroblast cell line. Samples were incubated in betacellulin polyclonal antibody (Product # PA5-47044). Recombinant Mouse Betacellulin/BTC stimulates proliferation in the Balb/3T3 mouse embryonic fibroblast cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse Betacellulin/BTC (2 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse Betacellulin/BTC Antigen Affinity-purified Polyclonal Antibody. The ND50 is typi... View More
Product Details
PA5-47044
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse Betacellulin/BTC Asp32-Gln118
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608106
Product Specific Information
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human BTC is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: betacellulin; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin
Gene Aliases: Bcn; Btc
UniProt ID: (Mouse) Q05928
Entrez Gene ID: (Mouse) 12223
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
positive regulation of urine volume
negative regulation of apoptotic process
positive regulation of cell differentiation
positive regulation of mitotic nuclear division
positive regulation of fibroblast proliferation
positive regulation of cell division
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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