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Invitrogen
betacellulin Polyclonal Antibody
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betacellulin Antibody (PA5-78887) in IHC (P)
Immunohistochemistry analysis of betacellulin on paraffin-embedded rat cerebellum tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with betacellulin polyclonal antibody (Product# PA5-78887) with a dilution of 2 µg/mL (overnight at 4°C), followed by biotinylated goat anti-rabbit IgG (30 minutes at 37... View More
Product Details
PA5-78887
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived rat Betacellulin recombinant protein (Position: D32-A177).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746003
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat PC-12 whole cell, rat RH35 whole cell. IHC: mouse lung tissue, rat lung tissue, rat brain tissue, rat cerebellum tissue.
Target Information
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: betacellulin; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin
Gene Aliases: Bcn; Btc
UniProt ID: (Mouse) Q05928
Entrez Gene ID: (Mouse) 12223, (Rat) 64022
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
positive regulation of urine volume
negative regulation of apoptotic process
positive regulation of cell differentiation
positive regulation of mitotic nuclear division
positive regulation of fibroblast proliferation
positive regulation of cell division
DNA replication
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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