Proteintech

c-Myb Polyclonal Antibody

FIGURE: 1 / 4

c-Myb Antibody (17800-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 17800-1-AP) c-Myb antibody at dilution of 1:3,000 incubated at room temperature for 1.5 hours.

c-Myb Antibody in Immunoprecipitation (IP)

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Product Details

17800-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 8 publications 8 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

c-Myb Fusion Protein Ag12021 (1-356 aa encoded by BC064955)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MARRPRHSI YSSDEDDEDF EMCDHDYDGL LPKSGKRHLG KTRWTREEDE KLKKLVEQNG TDDWKVIANY LPNRTDVQCQ HRWQKVLNPE LIKGPWTKEE DQRVIELVQK YGPKRWSVIA KHLKGRIGKQ CRERWHNHLN PEVKKTSWTE EEDRIIYQAH KRLGNRWAEI AKLLPGRTDN AIKNHWNSTM RRKVEQEGYL QESSKASQPA VATSFQKNSH LMGFAQAPPT AQLPATGQPT VNNDYSYYHI SEAQNVSSHV PYPVALHVNI VNVPQPAAAA IQRHYNDEDP EKEKRIKELE LLLMSTENEL KGQQVLPTQN HTCSYPGWHS TTIADHTRPH GDSAPVSCLG EHHSTPS (1-356 aa encoded by BC064955)

Target Information

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells.

Cancer genomics & proteomics

Moyama C,Fujita M,Okamoto H,Ii H,Nakata S

Tue Mar 07 00:00:00 UTC 2023

A Novel Antithrombocytopenia Agent, Rhizoma cibotii, Promotes Megakaryopoiesis and Thrombopoiesis through the PI3K/AKT, MEK/ERK, and JAK2/STAT3 Signaling Pathways.

International journal of molecular sciences

Chen W,Zhu L,Wang L,Zeng J,Wen M,Xu X,Zou L,Huang F,Huang Q,Qin D,Mei Q,Yang J,Wang Q,Wu J

Mon Nov 14 00:00:00 UTC 2022

Circ_0004087 interaction with SND1 promotes docetaxel resistance in prostate cancer by boosting the mitosis error correction mechanism.

Journal of experimental & clinical cancer research : CR

Chen L,Song Y,Hou T,Li X,Cheng L,Li Y,Xing Y

Fri Jun 03 00:00:00 UTC 2022

Circ_0004087 interaction with SND1 promotes docetaxel resistance in prostate cancer by boosting the mitosis error correction mechanism.

Journal of experimental & clinical cancer research : CR

Chen L,Song Y,Hou T,Li X,Cheng L,Li Y,Xing Y

Fri Jun 03 00:00:00 UTC 2022

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.

Nature communications

Niu T,De Rosny C,Chautard S,Rey A,Patoli D,Groslambert M,Cosson C,Lagrange B,Zhang Z,Visvikis O,Hacot S,Hologne M,Walker O,Wong J,Wang P,Ricci R,Henry T,Boyer L,Petrilli V,Py BF

Wed Oct 06 00:00:00 UTC 2021

Lidocaine and Bupivacaine Downregulate MYB and DANCR lncRNA by Upregulating miR-187-5p in MCF-7 Cells.

Frontiers in medicine

Lin CY,Tseng WT,Chang YY,Tsai MH,Chuang EY,Lu TP,Lai LC

Tue Feb 01 00:00:00 UTC 2022

Tcf1 and Lef1 provide constant supervision to mature CD8⁺ T cell identity and function by organizing genomic architecture.

Nature communications

Shan Q,Li X,Chen X,Zeng Z,Zhu S,Gai K,Peng W,Xue HH

Wed Oct 06 00:00:00 UTC 2021

[PARP10 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study].

Molekuliarnaia biologiia

Wu CF,Xiao M,Wang YL,Threadgill MD,Li M,Tang Y,Lin X,Yang L,Li QS,Li X

Wed Aug 19 00:00:00 UTC 2020

SND1 acts as an anti-apoptotic factor via regulating the expression of lncRNA UCA1 in hepatocellular carcinoma.

RNA biology

Cui X,Zhao C,Yao X,Qian B,Su C,Ren Y,Yao Z,Gao X,Yang J

Mon Jan 07 00:00:00 UTC 2019

SND1 acts as an anti-apoptotic factor via regulating the expression of lncRNA UCA1 in hepatocellular carcinoma.

RNA biology

Cui X,Zhao C,Yao X,Qian B,Su C,Ren Y,Yao Z,Gao X,Yang J

Mon Jan 07 00:00:00 UTC 2019

SND1 acts as an anti-apoptotic factor via regulating the expression of lncRNA UCA1 in hepatocellular carcinoma.

RNA biology

Cui X,Zhao C,Yao X,Qian B,Su C,Ren Y,Yao Z,Gao X,Yang J

Mon Jan 07 00:00:00 UTC 2019

SND1 acts as an anti-apoptotic factor via regulating the expression of lncRNA UCA1 in hepatocellular carcinoma.

RNA biology

Cui X,Zhao C,Yao X,Qian B,Su C,Ren Y,Yao Z,Gao X,Yang J

Mon Jan 07 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog

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Gene Aliases: c-myb; c-myb_CDS; Cmyb; efg; MYB

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UniProt ID: (Human) P10242

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Entrez Gene ID: (Human) 4602

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, RNA polymerase II transcription factor recruiting protein binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter mitotic cell cycle chromatin remodeling regulation of transcription, DNA-templated transcription from RNA polymerase II promoter positive regulation of T-helper cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of histone H3-K4 methylation positive regulation of histone H3-K9 methylation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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c-Myb Polyclonal Antibody

c-Myb Antibody (17800-1-AP) in WB

Product Details

17800-1-AP

Western Blot (WB)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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