Product References
FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression.
International wound journal
Feng G,Sun H,Piao M
MA1-980 was used in Western Blotting to investigate the role of FBXL6 in keloid fibroblasts, particularly its impact on cell proliferation and collagen deposition, and to explore its potential as a therapeutic target for keloid treatment.
Sun Jan 01 00:00:00 UTC 2023
FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression.
International wound journal
Feng G,Sun H,Piao M
MA1-980 was used in Western Blotting to investigate the role of FBXL6 in keloid fibroblasts, particularly its impact on cell proliferation and collagen deposition, and to explore its potential as a therapeutic target for keloid treatment.
Sun Jan 01 00:00:00 UTC 2023
ScRNA-seq revealed an immunosuppression state and tumor microenvironment heterogeneity related to lymph node metastasis in prostate cancer.
Experimental hematology & oncology
Xin S,Liu X,Li Z,Sun X,Wang R,Zhang Z,Feng X,Jin L,Li W,Tang C,Mei W,Cao Q,Wang H,Zhang J,Feng L,Ye L
MA1-980 was used in Immunocytochemistry-immunofluorescence to show that only EEF2 + and FOLH1 + luminal subgroups were present in LNM, and they appeared at the initial stage of luminal cell differentiation, which were comfirmed by verification experiments.
Tue May 23 00:00:00 UTC 2023
ScRNA-seq revealed an immunosuppression state and tumor microenvironment heterogeneity related to lymph node metastasis in prostate cancer.
Experimental hematology & oncology
Xin S,Liu X,Li Z,Sun X,Wang R,Zhang Z,Feng X,Jin L,Li W,Tang C,Mei W,Cao Q,Wang H,Zhang J,Feng L,Ye L
MA1-980 was used in Immunocytochemistry-immunofluorescence to show that only EEF2 + and FOLH1 + luminal subgroups were present in LNM, and they appeared at the initial stage of luminal cell differentiation, which were comfirmed by verification experiments.
Tue May 23 00:00:00 UTC 2023
ScRNA-seq revealed an immunosuppression state and tumor microenvironment heterogeneity related to lymph node metastasis in prostate cancer.
Experimental hematology & oncology
Xin S,Liu X,Li Z,Sun X,Wang R,Zhang Z,Feng X,Jin L,Li W,Tang C,Mei W,Cao Q,Wang H,Zhang J,Feng L,Ye L
MA1-980 was used in Immunocytochemistry-immunofluorescence to show that only EEF2 + and FOLH1 + luminal subgroups were present in LNM, and they appeared at the initial stage of luminal cell differentiation, which were comfirmed by verification experiments.
Tue May 23 00:00:00 UTC 2023
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
Journal for immunotherapy of cancer
Marquardt V,Theruvath J,Pauck D,Picard D,Qin N,Blümel L,Maue M,Bartl J,Ahmadov U,Langini M,Meyer FD,Cole A,Cruz-Cruz J,Graef CM,Wölfl M,Milde T,Witt O,Erdreich-Epstein A,Leprivier G,Kahlert U,Stefanski A,Stühler K,Keir ST,Bigner DD,Hauer J,Beez T,Knobbe-Thomsen CB,Fischer U,Felsberg J,Hansen FK,Vibhakar R,Venkatraman S,Cheshier SH,Reifenberger G,Borkhardt A,Kurz T,Remke M,Mitra S
MA1-980 was used in Immunoprecipitation to evaluate therapeutic vulnerabilities in MYC amplified MB, which sensitizes them to macrophage-mediated phagocytosis by targeting the CD47-signal regulatory protein α (SIRPα) innate checkpoint pathway.
Sun Jan 01 00:00:00 UTC 2023
The deubiquitinating enzyme USP37 promotes keloid fibroblasts proliferation and collagen production by regulating the c-Myc expression.
International wound journal
Piao M,Feng G
MA1-980 was used in Western Blot to promote the proliferation and collagen deposit of keloid fibroblasts, and USP37 could be targeted in future keloid therapy.
Mon May 01 00:00:00 UTC 2023
Detergent-insoluble PFN1 inoculation expedites disease onset and progression in PFN1 transgenic rats.
Frontiers in neuroscience
Cui S,Zhang T,Xiong X,Zhao J,Cao Q,Zhou H,Xia XG
MA1-980 was used in Immunoprecipitation to shed light on a novel mechanism that underscores the prion-like characteristics of pathogenic PFN1 in driving neurodegeneration in the context of PFN1-related ALS.
Fri Sep 27 00:00:00 UTC 2024
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species.
Science advances
Martín-Vega A,Ruiz-Peinado L,García-Gómez R,Herrero A,de la Fuente-Vivas D,Parvathaneni S,Caloto R,Morante M,von Kriegsheim A,Bustelo XR,Sacks DB,Casar B,Crespo P
MA1-980 was used in Immunoprecipitation to reveal that ERK trans-phosphorylation participates in KSR1-regulated adipogenesis, and it also underlies the modest cytotoxicity exhibited by KSR-directed inhibitors.
Wed Feb 15 00:00:00 UTC 2023
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species.
Science advances
Martín-Vega A,Ruiz-Peinado L,García-Gómez R,Herrero A,de la Fuente-Vivas D,Parvathaneni S,Caloto R,Morante M,von Kriegsheim A,Bustelo XR,Sacks DB,Casar B,Crespo P
MA1-980 was used in Immunoprecipitation to reveal that ERK trans-phosphorylation participates in KSR1-regulated adipogenesis, and it also underlies the modest cytotoxicity exhibited by KSR-directed inhibitors.
Wed Feb 15 00:00:00 UTC 2023
A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.
Genome research
Chen S,Liu Y,Zhang Y,Wierbowski SD,Lipkin SM,Wei X,Yu H
MA1-980 was used in Western Blotting to show that our framework bridges the gap between the statistical significance of mutational hotspots and their biological and clinical significance in human cancers.
Sat Jan 01 00:00:00 UTC 2022
Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport.
The Journal of cell biology
Lee J,Levin DE
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Wed Feb 09 00:00:00 UTC 2022
Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport.
The Journal of cell biology
Lee J,Levin DE
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Wed Feb 09 00:00:00 UTC 2022
Copper inhibits protein maturation in the secretory pathway by targeting the Sec61 translocon in Saccharomyces cerevisiae.
The Journal of biological chemistry
Saha N,Tomar RS
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Mon Aug 01 00:00:00 UTC 2022
Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology.
Cellular and molecular life sciences : CMLS
Heinze A,Schuldt C,Khudayberdiev S,van Bommel B,Hacker D,Schulz TG,Stringhi R,Marcello E,Mikhaylova M,Rust MB
MA1-980 was used in Western Blot to identify CAP1 as a novel regulator of the postsynaptic actin cytoskeleton that is essential for synaptic cofilin1 activity.
Thu Oct 20 00:00:00 UTC 2022
Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology.
Cellular and molecular life sciences : CMLS
Heinze A,Schuldt C,Khudayberdiev S,van Bommel B,Hacker D,Schulz TG,Stringhi R,Marcello E,Mikhaylova M,Rust MB
MA1-980 was used in Western Blot to identify CAP1 as a novel regulator of the postsynaptic actin cytoskeleton that is essential for synaptic cofilin1 activity.
Thu Oct 20 00:00:00 UTC 2022
Cyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes.
Nature communications
Shaw S,Knüsel S,Abbühl D,Naguleswaran A,Etzensperger R,Benninger M,Roditi I
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Feb 01 00:00:00 UTC 2022
Cyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes.
Nature communications
Shaw S,Knüsel S,Abbühl D,Naguleswaran A,Etzensperger R,Benninger M,Roditi I
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Feb 01 00:00:00 UTC 2022
Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.
Cell death and differentiation
Peng Y,Liu J,Wang Z,Cui C,Zhang T,Zhang S,Gao P,Hou Z,Liu H,Guo J,Zhang J,Wen Y,Wei W,Zhang L,Liu J,Long J
MA1-980 was used in Immunohistochemistry to indicate that OTUD6A is a physiological DUB for c-Myc in PrCa setting and specifically promotes prostatic tumorigenesis through stabilizing c-Myc oncoprotein.
Thu Sep 01 00:00:00 UTC 2022
Global Proximity Interactome of the Human Macroautophagy Pathway.
Autophagy
Tu YXI,Sydor AM,Coyaud E,Laurent EMN,Dyer D,Mellouk N,St-Germain J,Vernon RM,Forman-Kay JD,Li T,Hua R,Zhao K,Ridgway ND,Kim PK,Raught B,Brumell JH
MA1-980 was used in Western Blotting to perform proximity-dependent biotin identification (BioID) on 39 core human macroautophagy proteins, identifying over 700 unique high confidence proximity interactors with new putative connections between macroautophagic and essential cellular processes.
Sun May 01 00:00:00 UTC 2022
Mutagenic Analysis of the HIV Restriction Factor Shiftless.
Viruses
Jäger N,Ayyub SA,Korniy N,Peske F,Hoffmann M,Rodnina MV,Pöhlmann S
MA1-980 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to support the notion that SFL binds to the ribosome and the HIV RNA in order to block -1PRF and HIV infection, and suggest that the multimerization of SFL may be functionally important.
Thu Jun 30 00:00:00 UTC 2022
Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America
Ta N,Qu C,Wu H,Zhang D,Sun T,Li Y,Wang J,Wang X,Tang T,Chen Q,Liu L
MA1-980 was used in Immunocytochemistry-immunofluorescence to demonstrate that FUNDC2 modulates ferroptotic stress via regulating mitoGSH and further support a therapeutic strategy of cardioprotection by preventing mitoGSH depletion and ferroptosis.
Tue Sep 06 00:00:00 UTC 2022
Duck TRIM29 negatively regulates type I IFN production by targeting MAVS.
Frontiers in immunology
Li W,Song Y,Du Y,Huang Z,Zhang M,Chen Z,He Z,Ding Y,Zhang J,Zhao L,Sun H,Jiao P
MA1-980 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to demonstrate that duTRIM29 negatively regulates type I IFN production by targeting duMAVS in ducks.
Tue Jan 24 00:00:00 UTC 2023
Engineered protein-small molecule conjugates empower selective enzyme inhibition.
Cell chemical biology
Lewis AK,Harthorn A,Johnson SM,Lobb RR,Hackel BJ
MA1-980 was used in Flow Cytometry to discover protein-small molecule (PriSM) hybrids to combine unique pharmacophore activities and shapes with constrained, efficiently engineerable proteins.
Thu Feb 17 00:00:00 UTC 2022
Genomic and phenotypic characterization of 404 individuals with neurodevelopmental disorders caused by CTNNB1 variants.
Genetics in medicine : official journal of the American College of Medical Genetics
Kayumi S,Pérez-Jurado LA,Palomares M,Rangu S,Sheppard SE,Chung WK,Kruer MC,Kharbanda M,Amor DJ,McGillivray G,Cohen JS,García-Miñaúr S,van Eyk CL,Harper K,Jolly LA,Webber DL,Barnett CP,Santos-Simarro F,Pacio-Míguez M,Pozo AD,Bakhtiari S,Deardorff M,Dubbs HA,Izumi K,Grand K,Gray C,Mark PR,Bhoj EJ,Li D,Ortiz-Gonzalez XR,Keena B,Zackai EH,Goldberg EM,Perez de Nanclares G,Pereda A,Llano-Rivas I,Arroyo I,Fernández-Cuesta MÁ,Thauvin-Robinet C,Faivre L,Garde A,Mazel B,Bruel AL,Tress ML,Brilstra E,Fine AS,Crompton KE,Stegmann APA,Sinnema M,Stevens SCJ,Nicolai J,Lesca G,Lion-François L,Haye D,Chatron N,Piton A,Nizon M,Cogne B,Srivastava S,Bassetti J,Muss C,Gripp KW,Procopio RA,Millan F,Morrow MM,Assaf M,Moreno-De-Luca A,Joss S,Hamilton MJ,Bertoli M,Foulds N,McKee S,MacLennan AH,Gecz J,Corbett MA
MA1-980 was used in Western Blotting to investigate the range of clinical phenotypes owing to disruptions of CTNNB1 to determine the association between NEDSDV and CP.
Tue Nov 01 00:00:00 UTC 2022
Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells.
Cell metabolism
Fan Z,Turiel G,Ardicoglu R,Ghobrial M,Masschelein E,Kocijan T,Zhang J,Tan G,Fitzgerald G,Gorski T,Alvarado-Diaz A,Gilardoni P,Adams CM,Ghesquière B,De Bock K
MA1-980 was used in Functional assay to illustrate that spatial metabolic angiodiversity determines the angiogenic potential of muscle ECs.
Tue Sep 07 00:00:00 UTC 2021
Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
Blood
Sheng Y,Ma R,Yu C,Wu Q,Zhang S,Paulsen K,Zhang J,Ni H,Huang Y,Zheng Y,Qian Z
MA1-980 was used in ChIP assay to identify Nr4a1, Nr4a2, and Jmjd3, which are critical for the maintenance of hematopoietic stem cell (HSC) functions, as previously unrecognized downstream targets of c-Myc in HSCs.
Thu Feb 04 00:00:00 UTC 2021
Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype.
Molecular cancer research : MCR
Voigt E,Wallenburg M,Wollenzien H,Thompson E,Kumar K,Feiner J,McNally M,Friesen H,Mukherjee M,Afeworki Y,Kareta MS
MA1-980 was used in Immunohistochemistry to suggest that SOX2 can be associated with the switch of SCLC from an ASCL1 subtype to a NEUROD1 subtype.
Wed Dec 01 00:00:00 UTC 2021
Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus.
Molecular therapy oncolytics
Ma J,Jin C,Čančer M,Wang H,Ramachandran M,Yu D
MA1-980 was used in Immunohistochemistry (Paraffin) to suggest that distinct immune stimulation profiles are elicited when the same immunostimulatory factor is expressed by different OVs.
Fri Jun 25 00:00:00 UTC 2021
Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus.
Molecular therapy oncolytics
Ma J,Jin C,Čančer M,Wang H,Ramachandran M,Yu D
MA1-980 was used in Immunohistochemistry (Paraffin) to suggest that distinct immune stimulation profiles are elicited when the same immunostimulatory factor is expressed by different OVs.
Fri Jun 25 00:00:00 UTC 2021
Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus.
Molecular therapy oncolytics
Ma J,Jin C,Čančer M,Wang H,Ramachandran M,Yu D
MA1-980 was used in Immunohistochemistry (Paraffin) to suggest that distinct immune stimulation profiles are elicited when the same immunostimulatory factor is expressed by different OVs.
Fri Jun 25 00:00:00 UTC 2021
HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Frontiers in cell and developmental biology
Del Rosso G,Carlomagno Y,Todd TW,Jones CY,Prudencio M,Daughrity LM,Yue M,Jansen-West K,Tong J,Shao W,Wu Y,Castanedes-Casey M,Tabassian L,Oskarsson B,Ling K,Rigo F,Dickson DW,Yao TP,Petrucelli L,Cook CN,Zhang YJ
MA1-980 was used in Immunoprecipitation, Western Blot to evaluate whether the protein HDAC6 co-localizes with dipeptide repeat protein inclusions in a mouse model of frontotemporal dementia.
Tue May 03 00:00:00 UTC 2022
HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Frontiers in cell and developmental biology
Del Rosso G,Carlomagno Y,Todd TW,Jones CY,Prudencio M,Daughrity LM,Yue M,Jansen-West K,Tong J,Shao W,Wu Y,Castanedes-Casey M,Tabassian L,Oskarsson B,Ling K,Rigo F,Dickson DW,Yao TP,Petrucelli L,Cook CN,Zhang YJ
MA1-980 was used in Immunoprecipitation, Western Blot to evaluate whether the protein HDAC6 co-localizes with dipeptide repeat protein inclusions in a mouse model of frontotemporal dementia.
Tue May 03 00:00:00 UTC 2022
HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Frontiers in cell and developmental biology
Del Rosso G,Carlomagno Y,Todd TW,Jones CY,Prudencio M,Daughrity LM,Yue M,Jansen-West K,Tong J,Shao W,Wu Y,Castanedes-Casey M,Tabassian L,Oskarsson B,Ling K,Rigo F,Dickson DW,Yao TP,Petrucelli L,Cook CN,Zhang YJ
MA1-980 was used in Immunoprecipitation, Western Blot to evaluate whether the protein HDAC6 co-localizes with dipeptide repeat protein inclusions in a mouse model of frontotemporal dementia.
Tue May 03 00:00:00 UTC 2022
Large Multicohort Study Reveals a Prostate Cancer Susceptibility Allele at 5p15 Regulating TERT via Androgen Signaling-Orchestrated Chromatin Binding of E2F1 and MYC.
Frontiers in oncology
Dong X,Zhang Q,Hao J,Xie Q,Xu B,Zhang P,Lu H,Huang Q,Yang T,Wei GH,Na R,Gao P
MA1-980 was used in Chromatin immunoprecipitation and Western Blotting to investigate the roles of noncoding variations coordinated with androgen signaling and oncogenic transcription factors in mis-regulating TERT expression and driving PCa.
Mon Aug 19 00:00:00 UTC 2024
Large Multicohort Study Reveals a Prostate Cancer Susceptibility Allele at 5p15 Regulating TERT via Androgen Signaling-Orchestrated Chromatin Binding of E2F1 and MYC.
Frontiers in oncology
Dong X,Zhang Q,Hao J,Xie Q,Xu B,Zhang P,Lu H,Huang Q,Yang T,Wei GH,Na R,Gao P
MA1-980 was used in Chromatin immunoprecipitation and Western Blotting to investigate the roles of noncoding variations coordinated with androgen signaling and oncogenic transcription factors in mis-regulating TERT expression and driving PCa.
Mon Aug 19 00:00:00 UTC 2024
A Novel SEMA3G Mutation in Two Siblings Affected by Syndromic GnRH Deficiency.
Neuroendocrinology
Oleari R,André V,Lettieri A,Tahir S,Roth L,Paganoni A,Eberini I,Parravicini C,Scagliotti V,Cotellessa L,Bedogni F,De Martini LB,Corridori MV,Gulli S,Augustin HG,Gaston-Massuet C,Hussain K,Cariboni A
MA1-980 was used in Immunohistochemistry to assess the contribution of mutated Semaphorin 3G (SEMA3G) gene in the onset of a syndromic form of HH, characterized by intellectual disabilities and facial dysmorphic features.
Wed Nov 17 00:00:00 UTC 2021
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Deng Q,Wu L,Li Y,Zou L
MA1-980 was used in Western Blot to examine the role of myeloblastosis viral oncogene homolog-like 2 (MYBL2) in gastric cancer progression and investigate the underlying mechanisms.
Wed Sep 01 00:00:00 UTC 2021
Glypican 4 mediates Wnt transport between germ layers via signaling filopodia.
The Journal of cell biology
Hu B,Rodriguez JJ,Kakkerla Balaraju A,Gao Y,Nguyen NT,Steen H,Suhaib S,Chen S,Lin F
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Mon Dec 06 00:00:00 UTC 2021
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Theranostics
Taha-Mehlitz S,Bianco G,Coto-Llerena M,Kancherla V,Bantug GR,Gallon J,Ercan C,Panebianco F,Eppenberger-Castori S,von Strauss M,Staubli S,Bolli M,Peterli R,Matter MS,Terracciano LM,von Flüe M,Ng CKY,Soysal SD,Kollmar O,Piscuoglio S
MA1-980 was used in Western Blotting to investigate the putative role of adenylosuccinate lyase in colorectal carcinoma (CRC) carcinogenesis and response to antimetabolites.
Thu Jul 29 00:00:00 UTC 2021
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Theranostics
Taha-Mehlitz S,Bianco G,Coto-Llerena M,Kancherla V,Bantug GR,Gallon J,Ercan C,Panebianco F,Eppenberger-Castori S,von Strauss M,Staubli S,Bolli M,Peterli R,Matter MS,Terracciano LM,von Flüe M,Ng CKY,Soysal SD,Kollmar O,Piscuoglio S
MA1-980 was used in Western Blotting to investigate the putative role of adenylosuccinate lyase in colorectal carcinoma (CRC) carcinogenesis and response to antimetabolites.
Thu Jul 29 00:00:00 UTC 2021
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Theranostics
Taha-Mehlitz S,Bianco G,Coto-Llerena M,Kancherla V,Bantug GR,Gallon J,Ercan C,Panebianco F,Eppenberger-Castori S,von Strauss M,Staubli S,Bolli M,Peterli R,Matter MS,Terracciano LM,von Flüe M,Ng CKY,Soysal SD,Kollmar O,Piscuoglio S
MA1-980 was used in Western Blotting to investigate the putative role of adenylosuccinate lyase in colorectal carcinoma (CRC) carcinogenesis and response to antimetabolites.
Thu Jul 29 00:00:00 UTC 2021
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Theranostics
Taha-Mehlitz S,Bianco G,Coto-Llerena M,Kancherla V,Bantug GR,Gallon J,Ercan C,Panebianco F,Eppenberger-Castori S,von Strauss M,Staubli S,Bolli M,Peterli R,Matter MS,Terracciano LM,von Flüe M,Ng CKY,Soysal SD,Kollmar O,Piscuoglio S
MA1-980 was used in Western Blotting to investigate the putative role of adenylosuccinate lyase in colorectal carcinoma (CRC) carcinogenesis and response to antimetabolites.
Thu Jul 29 00:00:00 UTC 2021
Human VAMP3 Suppresses or Negatively Regulates Bax Induced Apoptosis in Yeast.
Biomedicines
Akintade DD,Chaudhuri B
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Tue Jan 19 00:00:00 UTC 2021
Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood.
International journal of molecular sciences
Michler P,Schedel A,Witschas M,Friedrich UA,Wagener R,Mehtonen J,Brozou T,Menzel M,Walter C,Nabi D,Pearce G,Erlacher M,Göhring G,Dugas M,Heinäniemi M,Borkhardt A,Stölzel F,Hauer J,Auer F
MA1-980 was used in Western Blot to show that the cells overexpressing the mutated POT1 display increased DNA damage and chromosomal instabilities compared to the wildtype counterpart.
Tue Oct 26 00:00:00 UTC 2021
ATRX proximal protein associations boast roles beyond histone deposition.
PLoS genetics
Scott WA,Dhanji EZ,Dyakov BJA,Dreseris ES,Asa JS,Grange LJ,Mirceta M,Pearson CE,Stewart GS,Gingras AC,Campos EI
MA1-980 was used in Proximity Ligation Assay to expand the repertoire of ATRX-associating proteins and functions.
Mon Nov 01 00:00:00 UTC 2021
Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Nature communications
Hoffmann J,Luxán G,Abplanalp WT,Glaser SF,Rasper T,Fischer A,Muhly-Reinholz M,Potente M,Assmus B,John D,Zeiher AM,Dimmeler S
MA1-980 was used in Immunocytochemistry to study the bone vascular niche in mice with post-myocardial infarction heart failure.
Fri Jun 25 00:00:00 UTC 2021
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung.
Respiratory research
Lüdtke TH,Wojahn I,Kleppa MJ,Schierstaedt J,Christoffels VM,Künzler P,Kispert A
MA1-980 was used in Immunoprecipitation to suggest that TBX2 interacts with homeobox and HMG-box transcription factors as well as with the NuRD chromatin remodeling complex to repress transcription of anti-proliferative genes in the pulmonary mesenchyme.
Wed Mar 17 00:00:00 UTC 2021
Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Cell metabolism
Gerlach BD,Ampomah PB,Yurdagul A,Liu C,Lauring MC,Wang X,Kasikara C,Kong N,Shi J,Tao W,Tabas I
MA1-980 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to suggest that signaling-triggered apoptotic cell-derived nucleotides can amplify this benefit by increasing the number of these macrophages.
Tue Dec 07 00:00:00 UTC 2021
A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.
International journal of molecular sciences
Uribe KB,Chemello K,Larrea-Sebal A,Benito-Vicente A,Galicia-Garcia U,Bourane S,Jaafar AK,Lambert G,Martín C
MA1-980 was used in Western Blot to propose that transient transfections of HEK293 cells with a plasmid encoding a PCSK9 variant followed by LDLR expression assessment by flow cytometry is sufficient to reliably determine its GOF or LOF status.
Sat Dec 18 00:00:00 UTC 2021
Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients.
ACS synthetic biology
Laurent E,Sieber A,Salzer B,Wachernig A,Seigner J,Lehner M,Geyeregger R,Kratzer B,Jäger U,Kunert R,Pickl WF,Traxlmayr MW
MA1-980 was used in Flow Cytometry to anticipate that the SuperFolder mutants generated in this study will be highly valuable tools for a range of applications in basic immunology and CD19-targeted cancer immunotherapy.
Fri May 21 00:00:00 UTC 2021
Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients.
ACS synthetic biology
Laurent E,Sieber A,Salzer B,Wachernig A,Seigner J,Lehner M,Geyeregger R,Kratzer B,Jäger U,Kunert R,Pickl WF,Traxlmayr MW
MA1-980 was used in Flow Cytometry to anticipate that the SuperFolder mutants generated in this study will be highly valuable tools for a range of applications in basic immunology and CD19-targeted cancer immunotherapy.
Fri May 21 00:00:00 UTC 2021
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Cell reports
Zhang Y,Hao J,Tarrago MG,Warner GM,Giorgadze N,Wei Q,Huang Y,He K,Chen C,Peclat TR,White TA,Ling K,Tchkonia T,Kirkland JL,Chini EN,Hu J
MA1-980 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to establish Fbf1tm1a/tm1a mice and discover that Fbf1tm1a/tm1a mice develop severe obesity, but surprisingly, are not predisposed to adverse metabolic complications.
Tue Aug 03 00:00:00 UTC 2021
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.
The Journal of experimental medicine
Tang J,Tu S,Lin G,Guo H,Yan C,Liu Q,Huang L,Tang N,Xiao Y,Pope RM,Rajaram MVS,Amer AO,Ahmer BM,Gunn JS,Wozniak DJ,Tao L,Coppola V,Zhang L,Langdon WY,Torrelles JB,Lipkowitz S,Zhang J
MA1-980 was used in Western Blotting to show the NLRP3 inflammasome is regulated from causing endotoxemia by K63- and K48-linked ubiquitination.
Mon Apr 06 00:00:00 UTC 2020
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.
The Journal of experimental medicine
Tang J,Tu S,Lin G,Guo H,Yan C,Liu Q,Huang L,Tang N,Xiao Y,Pope RM,Rajaram MVS,Amer AO,Ahmer BM,Gunn JS,Wozniak DJ,Tao L,Coppola V,Zhang L,Langdon WY,Torrelles JB,Lipkowitz S,Zhang J
MA1-980 was used in Western Blotting to show the NLRP3 inflammasome is regulated from causing endotoxemia by K63- and K48-linked ubiquitination.
Mon Apr 06 00:00:00 UTC 2020
Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America
Tagliatti E,Bello OD,Mendonça PRF,Kotzadimitriou D,Nicholson E,Coleman J,Timofeeva Y,Rothman JE,Krishnakumar SS,Volynski KE
MA1-980 was used in Immunohistochemistry to conclude that Ca2+-sensitive Syt1 oligomers, acting as an exocytosis clamp, are critical for maintaining the balance among the different modes of neurotransmitter release.
Tue Feb 18 00:00:00 UTC 2020
HSI2/VAL1 and HSL1/VAL2 function redundantly to repress DOG1 expression in Arabidopsis seeds and seedlings.
The New phytologist
Chen N,Wang H,Abdelmageed H,Veerappan V,Tadege M,Allen RD
MA1-980 was used in Western Blotting to study the roles of HSI2/VAL1 and HSL1/VAL2 in the repression of DOG1 in arabidopsis seeds.
Sat Aug 01 00:00:00 UTC 2020
HSI2/VAL1 and HSL1/VAL2 function redundantly to repress DOG1 expression in Arabidopsis seeds and seedlings.
The New phytologist
Chen N,Wang H,Abdelmageed H,Veerappan V,Tadege M,Allen RD
MA1-980 was used in Western Blotting to study the roles of HSI2/VAL1 and HSL1/VAL2 in the repression of DOG1 in arabidopsis seeds.
Sat Aug 01 00:00:00 UTC 2020
RAD54 promotes alternative lengthening of telomeres by mediating branch migration.
EMBO reports
Mason-Osann E,Terranova K,Lupo N,Lock YJ,Carson LM,Flynn RL
MA1-980 was used in Chromatin immunoprecipitation to demonstrate that RAD54 is enriched at ALT telomeres and promotes telomeric DNA synthesis through its ATPase-dependent branch migration activity.
Thu Jun 04 00:00:00 UTC 2020
High expression of Krüppel-like factor 5 is associated with poor prognosis in patients with colorectal cancer.
Cancer science
Takagi Y,Sakai N,Yoshitomi H,Furukawa K,Takayashiki T,Kuboki S,Takano S,Suzuki D,Kagawa S,Mishima T,Nakadai E,Miyauchi H,Matsubara H,Ohtsuka M
MA1-980 was used in Immunohistochemistry to correlate Krüppel-like factor 5 expression with colorectal cancer prognosis.
Mon Jun 01 00:00:00 UTC 2020
EXP1 is required for organisation of EXP2 in the intraerythrocytic malaria parasite vacuole.
Cellular microbiology
Nessel T,Beck JM,Rayatpisheh S,Jami-Alahmadi Y,Wohlschlegel JA,Goldberg DE,Beck JR
MA1-980 was used in Western Blot to reveal a novel PVM defect that indicates a critical role for EXP1 in maintaining proper organisation of EXP2 within the PVM.
Fri May 01 00:00:00 UTC 2020
The effect of copy number on α-synuclein's toxicity and its protective role in Bax-induced apoptosis, in yeast.
Bioscience reports
Akintade DD,Chaudhuri B
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Wed Sep 30 00:00:00 UTC 2020
Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis.
Molecular biology reports
Akintade DD,Chaudhuri B
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Tue Sep 01 00:00:00 UTC 2020
Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for Osteosarcoma.
Cancers
Pandya PH,Cheng L,Saadatzadeh MR,Bijangi-Vishehsaraei K,Tang S,Sinn AL,Trowbridge MA,Coy KL,Bailey BJ,Young CN,Ding J,Dobrota EA,Dyer S,Elmi A,Thompson Q,Barghi F,Shultz J,Albright EA,Shannon HE,Murray ME,Marshall MS,Ferguson MJ,Bertrand TE,Wurtz LD,Batra S,Li L,Renbarger JL,Pollok KE
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Wed Aug 26 00:00:00 UTC 2020
Tunable light and drug induced depletion of target proteins.
Nature communications
Deng W,Bates JA,Wei H,Bartoschek MD,Conradt B,Leonhardt H
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunocytochemistry
Thu Jan 16 00:00:00 UTC 2020
Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink.
Sensors (Basel, Switzerland)
Akintade DD,Chaudhuri B
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Tue Jul 21 00:00:00 UTC 2020
Trypanosoma brucei Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome.
mSphere
Crowe LP,Wilkinson CL,Nicholson KR,Morris MT
MA1-980 was used in Immunocytochemistry to forward our understanding of how the parasite-specific protein Pex13.2 functions in glycosome protein import and lays the foundation for future studies focused on blocking Pex13.2 function, which would be lethal to bloodstream-form parasites that reside in the mammalian bloodstream.
Wed Feb 19 00:00:00 UTC 2020
Trypanosoma brucei Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome.
mSphere
Crowe LP,Wilkinson CL,Nicholson KR,Morris MT
MA1-980 was used in Immunocytochemistry to forward our understanding of how the parasite-specific protein Pex13.2 functions in glycosome protein import and lays the foundation for future studies focused on blocking Pex13.2 function, which would be lethal to bloodstream-form parasites that reside in the mammalian bloodstream.
Wed Feb 19 00:00:00 UTC 2020
Trypanosoma brucei Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome.
mSphere
Crowe LP,Wilkinson CL,Nicholson KR,Morris MT
MA1-980 was used in Immunocytochemistry to forward our understanding of how the parasite-specific protein Pex13.2 functions in glycosome protein import and lays the foundation for future studies focused on blocking Pex13.2 function, which would be lethal to bloodstream-form parasites that reside in the mammalian bloodstream.
Wed Feb 19 00:00:00 UTC 2020
Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle.
mBio
Smith EP,Cotto-Rosario A,Borghesan E,Held K,Miller CN,Celli J
MA1-980 was used in Western Blotting to demonstrate that T4SS effectors BspB and RicA display epistatic interactions in Brucella replication.
Tue Mar 31 00:00:00 UTC 2020
Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity.
Cancer cell international
Cai J,Zhu W,Lin Y,Hu J,Liu X,Xu W,Liu Y,Hu C,He S,Gong S,Yan G,Liang J
MA1-980 was used in Immunohistochemistry to demonstrate the dependence of M1 virus on glycolysis and identify a candidate synergist for M1 virotherapy.
Mon Nov 02 00:00:00 UTC 2020
BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment.
Cell reports
Gama Braga L,Cisneros AF,Mathieu MM,Clerc M,Garcia P,Lottin B,Garand C,Thebault P,Landry CR,Elowe S
MA1-980 was used in Western Blot to elucidate a function for the BUBR1 pseudokinase domain in ensuring accurate and timely exit from mitosis.
Tue Nov 17 00:00:00 UTC 2020
Metabolic Reprogramming of Host Cells in Response to Enteroviral Infection.
Cells
Cheng ML,Chien KY,Lai CH,Li GJ,Lin JF,Ho HY
MA1-980 was used in Immunoprecipitation to suggest that virus may induce metabolic reprogramming of host cells to promote its replication through interactions between viral and host cell proteins.
Tue Feb 18 00:00:00 UTC 2020
Metabolic Reprogramming of Host Cells in Response to Enteroviral Infection.
Cells
Cheng ML,Chien KY,Lai CH,Li GJ,Lin JF,Ho HY
MA1-980 was used in Immunoprecipitation to suggest that virus may induce metabolic reprogramming of host cells to promote its replication through interactions between viral and host cell proteins.
Tue Feb 18 00:00:00 UTC 2020
Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.
Cell
Hancock ML,Meyer RC,Mistry M,Khetani RS,Wagschal A,Shin T,Ho Sui SJ,Näär AM,Flanagan JG
MA1-980 was used in Western Blot to show that IR associates with RNA polymerase II in the nucleus, with striking enrichment at promoters genome-wide.
Thu Apr 18 00:00:00 UTC 2019
MCC950 closes the active conformation of NLRP3 to an inactive state.
Nature chemical biology
Tapia-Abellán A,Angosto-Bazarra D,Martínez-Banaclocha H,de Torre-Minguela C,Cerón-Carrasco JP,Pérez-Sánchez H,Arostegui JI,Pelegrin P
MA1-980 was used in Immunocytochemistry-immunoflourescence to show the molecule sulfonylurea MCC950 induces a change from an 'open' conformation of NOD-like receptor pyrin domain-containing protein 3 to a closed form.
Sat Jun 01 00:00:00 UTC 2019
NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis and Medial Division Site Placement.
Current biology : CB
Willet AH,DeWitt AK,Beckley JR,Clifford DM,Gould KL
MA1-980 was used in Western Blot to explore how mid1 dissociates from the contractile ring during mitosis.
Mon Mar 18 00:00:00 UTC 2019
Control of leaf blade outgrowth and floral organ development by LEUNIG, ANGUSTIFOLIA3 and WOX transcriptional regulators.
The New phytologist
Zhang F,Wang H,Kalve S,Wolabu TW,Nakashima J,Golz JF,Tadege M
MA1-980 was used in Western Blotting to investigate how the activities of WOX transcriptional repressor WOX1/STF, the LEUNIG transcriptional corepressor and the ANGUSTIFOLIA3 transcriptional coactivator coordinate for roles in leaf blade outgrowth and flower development.
Sun Sep 01 00:00:00 UTC 2019
Control of leaf blade outgrowth and floral organ development by LEUNIG, ANGUSTIFOLIA3 and WOX transcriptional regulators.
The New phytologist
Zhang F,Wang H,Kalve S,Wolabu TW,Nakashima J,Golz JF,Tadege M
MA1-980 was used in Western Blotting to investigate how the activities of WOX transcriptional repressor WOX1/STF, the LEUNIG transcriptional corepressor and the ANGUSTIFOLIA3 transcriptional coactivator coordinate for roles in leaf blade outgrowth and flower development.
Sun Sep 01 00:00:00 UTC 2019
A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex.
PLoS biology
Choi CP,Moon AS,Back PS,Jami-Alahmadi Y,Vashisht AA,Wohlschlegel JA,Bradley PJ
MA1-980 was used in Western Blotting to study protein-protein interactions in Toxoplasma and provide insight into the architecture of the cytoskeletal network of the apicomplexan inner membrane complex.
Tue Oct 01 00:00:00 UTC 2019
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump.
Science signaling
Schneditz G,Elias JE,Pagano E,Zaeem Cader M,Saveljeva S,Long K,Mukhopadhyay S,Arasteh M,Lawley TD,Dougan G,Bassett A,Karlsen TH,Kaser A,Kaneider NC
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Jan 01 00:00:00 UTC 2019
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump.
Science signaling
Schneditz G,Elias JE,Pagano E,Zaeem Cader M,Saveljeva S,Long K,Mukhopadhyay S,Arasteh M,Lawley TD,Dougan G,Bassett A,Karlsen TH,Kaser A,Kaneider NC
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Jan 01 00:00:00 UTC 2019
LncRNA MACC1-AS1 sponges multiple miRNAs and RNA-binding protein PTBP1.
Oncogenesis
Zhang X,Zhou Y,Chen S,Li W,Chen W,Gu W
MA1-980 was used in Western Blotting to demonstrate cell growth can be modulated by sponging multiple miRNAs and RNA binding protein PTBP1 via lncRNA MACC1-AS1.
Tue Dec 10 00:00:00 UTC 2019
Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E.
Journal of cell science
Davidge B,Rebola KGO,Agbor LN,Sigmund CD,Singer JD
MA1-980 was used in Western Blotting to describe a mechanism whereby N-terminally truncated cyclin E can avoid the Cul3-mediated degradation pathway.
Wed Nov 06 00:00:00 UTC 2019
High HOXD4 protein expression in gastric adenocarcinoma tissues indicates unfavorable clinical outcomes.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Liu H,Tian H,Zhao J,Jia Y
MA1-980 was used in Western Blotting to examine the expression levels of homeobox D4 and dissect whether the HOXD4 expression is associated with aggressive clinicopathological outcomes of patients with gastric adenocarcinoma.
Thu Apr 04 00:00:00 UTC 2019
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination.
Frontiers in immunology
Rao Z,Chen X,Wu J,Xiao M,Zhang J,Wang B,Fang L,Zhang H,Wang X,Yang S,Chen Y
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Oct 27 00:00:00 UTC 2020
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination.
Frontiers in immunology
Rao Z,Chen X,Wu J,Xiao M,Zhang J,Wang B,Fang L,Zhang H,Wang X,Yang S,Chen Y
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Tue Oct 27 00:00:00 UTC 2020
The in vivo impact of MsLAC1, a Miscanthus laccase isoform, on lignification and lignin composition contrasts with its in vitro substrate preference.
BMC plant biology
He F,Machemer-Noonan K,Golfier P,Unda F,Dechert J,Zhang W,Hoffmann N,Samuels L,Mansfield SD,Rausch T,Wolf S
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Thu Dec 12 00:00:00 UTC 2019
Increased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells.
International journal of molecular sciences
Almars A,Chondrou PS,Onyido EK,Almozyan S,Seedhouse C,Babaei-Jadidi R,Nateri AS
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Tue Jun 04 00:00:00 UTC 2019
Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations.
Scientific reports
Ji C,Li Y,Kittredge A,Hopiavuori A,Ward N,Yao P,Fukuda Y,Zhang Y,Tsang SH,Yang T
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Fri Dec 13 00:00:00 UTC 2019
Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition.
Nature communications
Potok ME,Wang Y,Xu L,Zhong Z,Liu W,Feng S,Naranbaatar B,Rayatpisheh S,Wang Z,Wohlschlegel JA,Ausin I,Jacobsen SE
MA1-980 was used in Western Blotting to identify interacting partners of a conserved Arabidopsis SWR1 subunit actin related protein 6 (ARP6).
Fri Jul 26 00:00:00 UTC 2019
Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.
eLife
Tao Y,Mis M,Blazer L,Ustav M,Steinhart Z,Chidiac R,Kubarakos E,O'Brien S,Wang X,Jarvik N,Patel N,Adams J,Moffat J,Angers S,Sidhu SS
MA1-980 was used in Flow cytometry/Cell sorting to show that activation of Wnt signaling circuits with tailored FLAgs will enable precise delineation of functional outcomes directed by distinct receptor combinations and could provide a new class of therapeutics to unlock the promise of regenerative medicine.
Tue Aug 27 00:00:00 UTC 2019
Measles vector as a multigene delivery platform facilitating iPSC reprogramming.
Gene therapy
Wang Q,Vossen A,Ikeda Y,Devaux P
MA1-980 was used in Western Blot to present a highly efficient multi-transgene delivery system based on a vaccine strain of MV, a non-integrating RNA virus that has a long-standing safety record in humans.
Wed May 01 00:00:00 UTC 2019
A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus.
Nature communications
Flint M,Chatterjee P,Lin DL,McMullan LK,Shrivastava-Ranjan P,Bergeron É,Lo MK,Welch SR,Nichol ST,Tai AW,Spiropoulou CF
MA1-980 was used in Western Blotting to identify N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus.
Thu Jan 17 00:00:00 UTC 2019
Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway.
mBio
Chen T,Wagner AS,Tams RN,Eyer JE,Kauffman SJ,Gann ER,Fernandez EJ,Reynolds TB
MA1-980 was used in In Vitro Assay to report a novel upstream regulator of Cek1 activation and characterize the impact of Cek1 activity on fungal virulence.
Tue Sep 17 00:00:00 UTC 2019
Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins.
Nature protocols
Elegheert J,Behiels E,Bishop B,Scott S,Woolley RE,Griffiths SC,Byrne EFX,Chang VT,Stuart DI,Jones EY,Siebold C,Aricescu AR
MA1-980 was used in Immunohistochemistry to describe the design and step-by-step application of a lentiviral plasmid suite, termed pHR-CMV-TetO2, for the constitutive or inducible large-scale production of soluble and membrane proteins in HEK293 cell lines.
Sat Dec 01 00:00:00 UTC 2018
In vivo generation of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome.
EMBO molecular medicine
Pfeiffer A,Thalheimer FB,Hartmann S,Frank AM,Bender RR,Danisch S,Costa C,Wels WS,Modlich U,Stripecke R,Verhoeyen E,Buchholz CJ
MA1-980 was used in Immunohistochemistry to demonstrate the feasibility of in vivo reprogramming of human CD8+ CAR T cells active against CD19+ cells.
Thu Nov 01 00:00:00 UTC 2018
Lipase maturation factor 1 affects redox homeostasis in the endoplasmic reticulum.
The EMBO journal
Roberts BS,Babilonia-Rosa MA,Broadwell LJ,Wu MJ,Neher SB
MA1-980 was used in Western Blotting to study the mechanism of regulation of LPL folding by lipase maturation factor using an in vitro study.
Mon Oct 01 00:00:00 UTC 2018
A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus.
Proceedings of the National Academy of Sciences of the United States of America
Castanotto D,Zhang X,Alluin J,Zhang X,Rüger J,Armstrong B,Rossi J,Riggs A,Stein CA
MA1-980 was used in Western Blotting to study the response of the nuclear transport of oligonucleotides, siRNAs, and miRNAs to cellular stress.
Tue Jun 19 00:00:00 UTC 2018
HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
The Plant cell
Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in ChIP assay
Thu Mar 01 00:00:00 UTC 2018
HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
The Plant cell
Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in ChIP assay
Thu Mar 01 00:00:00 UTC 2018
HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
The Plant cell
Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in ChIP assay
Thu Mar 01 00:00:00 UTC 2018
Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.
Current biology : CB
Combes G,Barysz H,Garand C,Gama Braga L,Alharbi I,Thebault P,Murakami L,Bryne DP,Stankovic S,Eyers PA,Bolanos-Garcia VM,Earnshaw WC,Maciejowski J,Jallepalli PV,Elowe S
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Mon Mar 19 00:00:00 UTC 2018
Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.
Current biology : CB
Combes G,Barysz H,Garand C,Gama Braga L,Alharbi I,Thebault P,Murakami L,Bryne DP,Stankovic S,Eyers PA,Bolanos-Garcia VM,Earnshaw WC,Maciejowski J,Jallepalli PV,Elowe S
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunoprecipitation
Mon Mar 19 00:00:00 UTC 2018
Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation.
Frontiers in immunology
Muhammad K,Rudolf R,Pham DAT,Klein-Hessling S,Takata K,Matsushita N,Ellenrieder V,Kondo E,Serfling E
MA1-980 was used in Western Blotting to investigate the role of transcription factor NFATc1 (also designated as NFAT2) in plasma cell formation.
Thu Feb 14 00:00:00 UTC 2019
Host Factor SPCS1 Regulates the Replication of Japanese Encephalitis Virus through Interactions with Transmembrane Domains of NS2B.
Journal of virology
Ma L,Li F,Zhang JW,Li W,Zhao DM,Wang H,Hua RH,Bu ZG
MA1-980 was used in Western Blotting to investigate the mechanism through which signal peptidase complex subunit 1 regulates the replication of flaviviruses.
Fri Jun 15 00:00:00 UTC 2018
CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
International journal of molecular medicine
Li ZQ,Wu WR,Zhao C,Zhao C,Zhang XL,Yang Z,Pan J,Si WK
MA1-980 was used in Western Blotting to demonstrate that cysteine-rich 61 may be involved in the progression of the hepatic cirrhosis-hepatocellular carcinoma axis through regulating hepatic stellate cells.
Thu Mar 01 00:00:00 UTC 2018
Downregulation of ROS1 enhances the therapeutic efficacy of arsenic trioxide in acute myeloid leukemia cell lines.
Oncology letters
Li J
MA1-980 was used in Western Blotting to investigate the function of ROS proto-oncogene 1 receptor tyrosine kinase in regulating the migration and proliferation of acute myeloid leukaemia cells through Wnt/Β-catenin signalling, and in arsenic trioxide treatment.
Fri Jun 01 00:00:00 UTC 2018
Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide.
ACS omega
Derf A,Mudududdla R,Akintade D,Williams IS,Abdullaha M,Chaudhuri B,Bharate SB
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Fri Aug 31 00:00:00 UTC 2018
The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast.
PloS one
Maksimov V,Oya E,Tanaka M,Kawaguchi T,Hachisuka A,Ekwall K,Bjerling P,Nakayama JI
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in ChIP assay
Thu Jan 17 00:00:00 UTC 2019
The GIS2 Gene Is Repressed by a Zinc-Regulated Bicistronic RNA in Saccharomyces cerevisiae.
Genes
Taggart J,Wang Y,Weisenhorn E,MacDiarmid CW,Russell J,Coon JJ,Eide DJ
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Western Blot
Wed Sep 19 00:00:00 UTC 2018
Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice.
Nature communications
Barragán-Iglesias P,Lou TF,Bhat VD,Megat S,Burton MD,Price TJ,Campbell ZT
MA1-980 was used in Western Blotting to demonstrate that Poly(A)-binding protein is integral for nociceptive plasticity.
Tue Jan 02 00:00:00 UTC 2018
Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi.
Frontiers in microbiology
Bonfim-Melo A,Ferreira ÉR,Mortara RA
MA1-980 was used in Immunocytochemistry-immunoflourescence to evaluate the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by Trypanosoma cruzi extracellular amastigotes.
Thu Oct 01 00:00:00 UTC 2020
Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.
Nature communications
Campbell H,Fleming N,Roth I,Mehta S,Wiles A,Williams G,Vennin C,Arsic N,Parkin A,Pajic M,Munro F,McNoe L,Black M,McCall J,Slatter TL,Timpson P,Reddel R,Roux P,Print C,Baird MA,Braithwaite AW
MA1-980 was used in Western Blotting to investigate the role of IL-6 in tumourigenesis in Δ122p53 mice.
Wed Jan 17 00:00:00 UTC 2018
VEGFR2-specific FnCAR effectively redirects the cytotoxic activity of T cells and YT NK cells.
Oncotarget
Kulemzin SV,Gorchakov AA,Chikaev AN,Kuznetsova VV,Volkova OY,Matvienko DA,Petukhov AV,Zaritskey AY,Taranin AV
MA1-980 was used in Flow cytometry/Cell sorting to study the utility of fibronectin type III domains in chimeric antigen receptors for antigen recognition.
Tue Feb 06 00:00:00 UTC 2018
Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis.
Nucleic acids research
Shao P,Liu Q,Maina PK,Cui J,Bair TB,Li T,Umesalma S,Zhang W,Qi HH
Published figure using c-Myc monoclonal antibody (Product # MA1-980) in Immunohistochemistry
Tue Feb 28 00:00:00 UTC 2017
Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis.
American journal of human genetics
Macia MS,Halbritter J,Delous M,Bredrup C,Gutter A,Filhol E,Mellgren AEC,Leh S,Bizet A,Braun DA,Gee HY,Silbermann F,Henry C,Krug P,Bole-Feysot C,Nitschké P,Joly D,Nicoud P,Paget A,Haugland H,Brackmann D,Ahmet N,Sandford R,Cengiz N,Knappskog PM,Boman H,Linghu B,Yang F,Oakeley EJ,Saint Mézard P,Sailer AW,Johansson S,Rødahl E,Saunier S,Hildebrandt F,Benmerah A
MA1-980 was used in western blot to identify MAPKBP1 mutations as a genetic cause of juvenile or late-onset and cilia-independent nephronophthisis
Thu Feb 02 00:00:00 UTC 2017
Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly.
Journal of virology
Cifuentes-Muñoz N,Sun W,Ray G,Schmitt PT,Webb S,Gibson K,Dutch RE,Schmitt AP
MA1-980 was used in Western Blotting to study how endosomal F trafficking affects Hendra virus assembly.
Sat Jul 15 00:00:00 UTC 2017
Clinical-scale expansion of CD34+ cord blood cells amplifies committed progenitors and rapid scid repopulation cells.
New biotechnology
Casamayor-Genescà A,Pla A,Oliver-Vila I,Pujals-Fonts N,Marín-Gallén S,Caminal M,Pujol-Autonell I,Carrascal J,Vives-Pi M,Garcia J,Vives J
MA1980 was used in ELISA to optimize a method to generate granulocyte lineage-committed progenitors from umbilical cord blood samples
Sat Mar 25 00:00:00 UTC 2017
Intact NYN/PIN-Like Domain is Crucial for the Degradation of Inflammation-Related Transcripts by ZC3H12D.
Journal of cellular biochemistry
Wawro M,Kochan J,Krzanik S,Jura J,Kasza A
MA1-980 was used in RNA immunoprecipitation and immunocytochemistry to elucidate the role of ZC3H12D
Wed Mar 01 00:00:00 UTC 2017
Intact NYN/PIN-Like Domain is Crucial for the Degradation of Inflammation-Related Transcripts by ZC3H12D.
Journal of cellular biochemistry
Wawro M,Kochan J,Krzanik S,Jura J,Kasza A
MA1-980 was used in RNA immunoprecipitation and immunocytochemistry to elucidate the role of ZC3H12D
Wed Mar 01 00:00:00 UTC 2017
Repression of Middle Sporulation Genes in Saccharomyces cerevisiae by the Sum1-Rfm1-Hst1 Complex Is Maintained by Set1 and H3K4 Methylation.
G3 (Bethesda, Md.)
Jaiswal D,Jezek M,Quijote J,Lum J,Choi G,Kulkarni R,Park D,Green EM
MA1-980 was used in Chromatin immunoprecipitation to show that Set1, and H3K4me2, are implicated in repression of a subset of middle sporulation genes during vegetative growth.
Mon Dec 04 00:00:00 UTC 2017
Repression of Middle Sporulation Genes in Saccharomyces cerevisiae by the Sum1-Rfm1-Hst1 Complex Is Maintained by Set1 and H3K4 Methylation.
G3 (Bethesda, Md.)
Jaiswal D,Jezek M,Quijote J,Lum J,Choi G,Kulkarni R,Park D,Green EM
MA1-980 was used in Chromatin immunoprecipitation to show that Set1, and H3K4me2, are implicated in repression of a subset of middle sporulation genes during vegetative growth.
Mon Dec 04 00:00:00 UTC 2017
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nature communications
Wu G,Yuan M,Shen S,Ma X,Fang J,Zhu L,Sun L,Liu Z,He X,Huang D,Li T,Li C,Wu J,Hu X,Li Z,Song L,Qu K,Zhang H,Gao P
MA1-980 was used in Western Blotting to identify an unexpected role of Menin in enhancing the transactivity of oncogene MYC in a way independent of H3K4me3 activity.
Fri May 05 00:00:00 UTC 2017
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
eLife
Chang TY,Chen C,Lee M,Chang YC,Lu CH,Lu ST,Wang DY,Wang A,Guo CL,Cheng PL
MA1-980 was used in Immunofluorescence to reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner.
Fri Dec 22 00:00:00 UTC 2017
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
eLife
Chang TY,Chen C,Lee M,Chang YC,Lu CH,Lu ST,Wang DY,Wang A,Guo CL,Cheng PL
MA1-980 was used in Immunofluorescence to reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner.
Fri Dec 22 00:00:00 UTC 2017
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
eLife
Chang TY,Chen C,Lee M,Chang YC,Lu CH,Lu ST,Wang DY,Wang A,Guo CL,Cheng PL
MA1-980 was used in Immunofluorescence to reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner.
Fri Dec 22 00:00:00 UTC 2017
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
eLife
Chang TY,Chen C,Lee M,Chang YC,Lu CH,Lu ST,Wang DY,Wang A,Guo CL,Cheng PL
MA1-980 was used in Immunofluorescence to reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner.
Fri Dec 22 00:00:00 UTC 2017
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
eLife
Chang TY,Chen C,Lee M,Chang YC,Lu CH,Lu ST,Wang DY,Wang A,Guo CL,Cheng PL
MA1-980 was used in Immunofluorescence to reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner.
Fri Dec 22 00:00:00 UTC 2017
Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells.
Scientific reports
Zorniak M,Clark PA,Umlauf BJ,Cho Y,Shusta EV,Kuo JS
MA1-980 was used in Flow cytometry/Cell sorting to study whether the glioblastoma stem-like cell surface proteome could be mined with a yeast display antibody library to reveal novel immunophenotypes.
Mon Nov 20 00:00:00 UTC 2017
PCH1 and PCHL promote photomorphogenesis in plants by controlling phytochrome B dark reversion.
Nature communications
Enderle B,Sheerin DJ,Paik I,Kathare PK,Schwenk P,Klose C,Ulbrich MH,Huq E,Hiltbrunner A
MA1-980 was used in Western Blotting to elucidate the role of the homologous phytochrome B-binding proteins, PCH1 and PCHL, in enhancing light sensitivity in plants.
Wed Dec 20 00:00:00 UTC 2017
Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease.
Scientific reports
Hubmacher D,Schneider M,Berardinelli SJ,Takeuchi H,Willard B,Reinhardt DP,Haltiwanger RS,Apte SS
MA1980 was used in western blot to analyze the expression and characteristics of the secreted metalloprotease ADAMTS17 in regards to fibrillin microfibrils
Wed Feb 08 00:00:00 UTC 2017
DELAY OF GERMINATION1 requires PP2C phosphatases of the ABA signalling pathway to control seed dormancy.
Nature communications
Née G,Kramer K,Nakabayashi K,Yuan B,Xiang Y,Miatton E,Finkemeier I,Soppe WJJ
MA1-980 was used in Western Blotting to describe four phosphatases that interact with DOG1 in seeds.
Thu Jul 13 00:00:00 UTC 2017
Cellular prion protein targets amyloid-β fibril ends via its C-terminal domain to prevent elongation.
The Journal of biological chemistry
Bove-Fenderson E,Urano R,Straub JE,Harris DA
MA1-980 was used in Surface Plasmon Resonance to study the effect of PrPc on AB polymerisation and characterise the molecular details of their interaction.
Fri Oct 13 00:00:00 UTC 2017
X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.
Nature communications
Olcese C,Patel MP,Shoemark A,Kiviluoto S,Legendre M,Williams HJ,Vaughan CK,Hayward J,Goldenberg A,Emes RD,Munye MM,Dyer L,Cahill T,Bevillard J,Gehrig C,Guipponi M,Chantot S,Duquesnoy P,Thomas L,Jeanson L,Copin B,Tamalet A,Thauvin-Robinet C,Papon JF,Garin A,Pin I,Vera G,Aurora P,Fassad MR,Jenkins L,Boustred C,Cullup T,Dixon M,Onoufriadis A,Bush A,Chung EM,Antonarakis SE,Loebinger MR,Wilson R,Armengot M,Escudier E,Hogg C,Amselem S,Sun Z,Bartoloni L,Blouin JL,Mitchison HM
MA1-980 was used in Western blotting following immunoprecipitation to propose that PIH1D3, a protein that emerges as a new player of the cytoplasmic pre-assembly pathway, is part of a complementary conserved R2TP-like HSP90 co-chaperone complex, the loss of which affects assembly of a subset of inner arm dyneins.
Wed Feb 08 00:00:00 UTC 2017
X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.
Nature communications
Olcese C,Patel MP,Shoemark A,Kiviluoto S,Legendre M,Williams HJ,Vaughan CK,Hayward J,Goldenberg A,Emes RD,Munye MM,Dyer L,Cahill T,Bevillard J,Gehrig C,Guipponi M,Chantot S,Duquesnoy P,Thomas L,Jeanson L,Copin B,Tamalet A,Thauvin-Robinet C,Papon JF,Garin A,Pin I,Vera G,Aurora P,Fassad MR,Jenkins L,Boustred C,Cullup T,Dixon M,Onoufriadis A,Bush A,Chung EM,Antonarakis SE,Loebinger MR,Wilson R,Armengot M,Escudier E,Hogg C,Amselem S,Sun Z,Bartoloni L,Blouin JL,Mitchison HM
MA1-980 was used in Western blotting following immunoprecipitation to propose that PIH1D3, a protein that emerges as a new player of the cytoplasmic pre-assembly pathway, is part of a complementary conserved R2TP-like HSP90 co-chaperone complex, the loss of which affects assembly of a subset of inner arm dyneins.
Wed Feb 08 00:00:00 UTC 2017
Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse.
Proceedings of the National Academy of Sciences of the United States of America
Kanemori Y,Koga Y,Sudo M,Kang W,Kashiwabara S,Ikawa M,Hasuwa H,Nagashima K,Ishikawa Y,Ogonuki N,Ogura A,Baba T
MA1-980 was used in immunocytochemistry to study regulation by pre-mRNA alternative splicing of Acrbp in the mouse by biogenesis of sperm acrosome
Tue Jun 28 00:00:00 UTC 2016
The NPC2 protein: A novel dog allergen.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
Khurana T,Newman-Lindsay S,Young PR,Slater JE
MA1980 was used in western blot to discuss dog allergens such as Can f 1
Sun May 01 00:00:00 UTC 2016
The levels of epithelial anchor proteins β-catenin and zona occludens-1 are altered by E7 of human papillomaviruses 5 and 8.
The Journal of general virology
Heuser S,Hufbauer M,Marx B,Tok A,Majewski S,Pfister H,Akgül B
MA1980 was used in western blot to show that beta-catenin and ZO-1 are targets of E7 of the oncogenic human papillomaviruses types 5 and 8
Mon Feb 01 00:00:00 UTC 2016
The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregation.
Molecular biology of the cell
Fees CP,Aiken J,O'Toole ET,Giddings TH,Moore JK
MA1-980 was used in western blot to study promotion of proper chromosome segregation by the negatively charged carboxy-terminal tail of beta-tubulin
Wed Jun 01 00:00:00 UTC 2016
IF-combined smRNA FISH reveals interaction of MCPIP1 protein with IER3 mRNA.
Biology open
Kochan J,Wawro M,Kasza A
MA1-980 was used in Immunoprecipitation to demonstrate the involvement of MCPIP1 in the regulation of IER3 mRNA levels.
Fri Jul 15 00:00:00 UTC 2016
IF-combined smRNA FISH reveals interaction of MCPIP1 protein with IER3 mRNA.
Biology open
Kochan J,Wawro M,Kasza A
MA1-980 was used in Immunoprecipitation to demonstrate the involvement of MCPIP1 in the regulation of IER3 mRNA levels.
Fri Jul 15 00:00:00 UTC 2016
IF-combined smRNA FISH reveals interaction of MCPIP1 protein with IER3 mRNA.
Biology open
Kochan J,Wawro M,Kasza A
MA1-980 was used in Immunoprecipitation to demonstrate the involvement of MCPIP1 in the regulation of IER3 mRNA levels.
Fri Jul 15 00:00:00 UTC 2016
Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta.
BMC biology
Kuzuya A,Zoltowska KM,Post KL,Arimon M,Li X,Svirsky S,Maesako M,Muzikansky A,Gautam V,Kovacs D,Hyman BT,Berezovska O
MA1-980 was used in western blot to study the activity-driven interaction between presenilin 1 and synaptotagmin 1 and links to calcium, amyloid beta, and synapse
Thu Mar 31 00:00:00 UTC 2016
Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.
PLoS genetics
Harris CJ,Husmann D,Liu W,Kasmi FE,Wang H,Papikian A,Pastor WA,Moissiard G,Vashisht AA,Dangl JL,Wohlschlegel JA,Jacobsen SE
MA1-980 was used in western blot to study the formation of nuclear bodies and repression of a large number of protein-coding genes by arabidopsis AtMORC4 and AtMORC7
Sun May 01 00:00:00 UTC 2016
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.
Scientific reports
Dubail J,Vasudevan D,Wang LW,Earp SE,Jenkins MW,Haltiwanger RS,Apte SS
MA1-980 was used in western blot describe a role for ADAMTS9 in ocular morphogenesis
Fri Sep 30 00:00:00 UTC 2016
Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion.
The Journal of biological chemistry
Boateng LR,Bennin D,De Oliveira S,Huttenlocher A
MA1980 was used in western blot to report that mammalian actin-binding protein-1 and FHL2 are binding partners that regulate Rho GTPase signaling and breast cancer cell invasion
Fri Jul 01 00:00:00 UTC 2016
Postnatal Gene Therapy Improves Spatial Learning Despite the Presence of Neuronal Ectopia in a Model of Neuronal Migration Disorder.
Genes
Hu H,Liu Y,Bampoe K,He Y,Yu M
MA1-980 was used in western blot to propose that postnatal gene therapy improves spatial learning even in the presence of neuronal ectopia
Tue Nov 29 00:00:00 UTC 2016
Concerted Action of PGC-1-related Coactivator (PRC) and c-MYC in the Stress Response to Mitochondrial Dysfunction.
The Journal of biological chemistry
Gleyzer N,Scarpulla RC
MA1-980 was used in Western Blotting to study the role of c-MYC in the PRC-dependent response to mitochondrial stress.
Fri Dec 02 00:00:00 UTC 2016
XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma.
Oncotarget
Turner JG,Kashyap T,Dawson JL,Gomez J,Bauer AA,Grant S,Dai Y,Shain KH,Meads M,Landesman Y,Sullivan DM
MA1980 was used in western blot to ask if selinexor, when combined with bortezomib or carfilzomib, attenuates resistance in multiple myeloma samples
Tue Nov 29 00:00:00 UTC 2016
T cell receptor dwell times control the kinase activity of Zap70.
Nature immunology
Klammt C,Novotná L,Li DT,Wolf M,Blount A,Zhang K,Fitchett JR,Lillemeier BF
MA1-980 was used in ELISA and western blot to study how conformational changes control T cell receptor association and activity of Zap70
Tue Sep 01 00:00:00 UTC 2015
T cell receptor dwell times control the kinase activity of Zap70.
Nature immunology
Klammt C,Novotná L,Li DT,Wolf M,Blount A,Zhang K,Fitchett JR,Lillemeier BF
MA1-980 was used in ELISA and western blot to study how conformational changes control T cell receptor association and activity of Zap70
Tue Sep 01 00:00:00 UTC 2015
Identification and molecular characterisation of a homozygous missense mutation in the ADAMTS10 gene in a patient with Weill-Marchesani syndrome.
European journal of human genetics : EJHG
Steinkellner H,Etzler J,Gogoll L,Neesen J,Stifter E,Brandau O,Laccone F
MA1-980 was used in Western Blotting to identify and characterise a homozygous missense mutation of the ADAMTS10 gene in a patient with Weill-Marchesani syndrome.
Tue Sep 01 00:00:00 UTC 2015
Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3.
Journal of physiology and biochemistry
Sun Y,Fu A,Xu W,Chao JR,Moshiach S,Morris SW
MA1-980 was used in immunoprecipitation and western blot to study promotion of apoptosis by myeloid leukemia factor 1 interference with Bcl-XL and function regulated by 14-3-3
Tue Dec 01 00:00:00 UTC 2015
The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling.
Investigative ophthalmology & visual science
Taylor SM,Alvarez-Delfin K,Saade CJ,Thomas JL,Thummel R,Fadool JM,Hitchcock PF
MA1-980 was used in Immunohistochemistry to identify the signalling pathways through which NeuroD functions.
Sun Nov 01 00:00:00 UTC 2015
Studies of the TLR4-associated protein MD-2 using yeast-display and mutational analyses.
Molecular immunology
Mattis DM,Chervin AS,Ranoa DR,Kelley SL,Tapping RI,Kranz DM
MA1-980 was used in Flow Cytometry to examine the molecular details of the interaction of myeloid differentiation factor 2 (MD-2) with lipopolysaccharide and Toll-like receptor 4.
Tue Dec 01 00:00:00 UTC 2015
VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability.
Biochemical and biophysical research communications
Yu X,Chen S,Hou P,Wang M,Chen Y,Guo D
MA1-980 was used in western blot to identify nsp16 binding partners using a yeast two-hybrid screen
Fri Apr 03 00:00:00 UTC 2015
Tyr724 phosphorylation of ELMO1 by Src is involved in cell spreading and migration via Rac1 activation.
Cell communication and signaling : CCS
Makino Y,Tsuda M,Ohba Y,Nishihara H,Sawa H,Nagashima K,Tanaka S
MA1-980 was used in Western Blotting to identify novel tyrosine residues of ELMO1 phosphorylated by Src-family tyrosine kinases, and examine the effects on Rac1 activity, cell adhesion, spreading, and cell motility on extracellular matrix.
Sat Jul 25 00:00:00 UTC 2015
MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.
Molecular and clinical oncology
Mundim FG,Pasini FS,Brentani MM,Soares FA,Nonogaki S,Waitzberg AF
MA1-980 was used in immunohistochemistry to investigate markers expressed by stromal cells in breast cancer patients.
Fri May 01 00:00:00 UTC 2015
Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption.
PloS one
Hadzic E,Catillon M,Halavatyi A,Medves S,Van Troys M,Moes M,Baird MA,Davidson MW,Schaffner-Reckinger E,Ampe C,Friederich E
MA1-980 was used in immunocytochemistry to investigate the interaction between zyxin and Tes
Mon Jun 13 00:00:00 UTC 2016
Novel components of the Toxoplasma inner membrane complex revealed by BioID.
mBio
Chen AL,Kim EW,Toh JY,Vashisht AA,Rashoff AQ,Van C,Huang AS,Moon AS,Bell HN,Bentolila LA,Wohlschlegel JA,Bradley PJ
MA1-980 was used in immunocytochemistry to use BioID to find novel components of the Toxoplasm inner membrane complex
Tue Feb 17 00:00:00 UTC 2015
Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation.
Nature communications
Asghar A,Lajeunesse A,Dulla K,Combes G,Thebault P,Nigg EA,Elowe S
MA1-980 was used in immunocytochemistry and western blot to elucidate the regulation and dynamics of H2A-T120 phosphorylation by Bub1
Thu Sep 24 00:00:00 UTC 2015
Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells.
Cancer research
Izumi H,Kaneko Y
MA1-980 was used in immunocytochemistry to investigate the role of asymmetric cell division during tumorigenesis
Wed Oct 01 00:00:00 UTC 2014
Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers.
Proceedings of the National Academy of Sciences of the United States of America
Moissiard G,Bischof S,Husmann D,Pastor WA,Hale CJ,Yen L,Stroud H,Papikian A,Vashisht AA,Wohlschlegel JA,Jacobsen SE
MA1-980 was used in western blot to study the role of heteromer formation in transcriptional gene silencing by the Arabidopsis homologues of mouse MORC genes
Tue May 20 00:00:00 UTC 2014
RON5 is critical for organization and function of the Toxoplasma moving junction complex.
PLoS pathogens
Beck JR,Chen AL,Kim EW,Bradley PJ
MA1-980 was used in western blot to determine the role of RON5 as a critical component for function and organization of the Toxoplasma moving junction complex
Sat Mar 01 00:00:00 UTC 2014
Loss of the tectorial membrane protein CEACAM16 enhances spontaneous, stimulus-frequency, and transiently evoked otoacoustic emissions.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Cheatham MA,Goodyear RJ,Homma K,Legan PK,Korchagina J,Naskar S,Siegel JH,Dallos P,Zheng J,Richardson GP
MA1-980 was used in Immunoprecipitation to study the structural and functional significance of carcinoembryonic antigen-related cell adhesion molecule 16.
Wed Jul 30 00:00:00 UTC 2014
Identification of two novel Shank3 transcripts in the developing mouse neocortex.
Journal of neurochemistry
Waga C,Asano H,Sanagi T,Suzuki E,Nakamura Y,Tsuchiya A,Itoh M,Goto Y,Kohsaka S,Uchino S
MA1-980 was used in immunohistochemistry to study the role in the developing murine neocortex of two novel transcripts of the Shank3 synaptic scaffold protein
Wed Jan 01 00:00:00 UTC 2014
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons.
Nature neuroscience
Dobbin MM,Madabhushi R,Pan L,Chen Y,Kim D,Gao J,Ahanonu B,Pao PC,Qiu Y,Zhao Y,Tsai LH
MA1-980 was used in western blot to study the roles of SIRT1, ATM and HDAC1 in the DNA double-strand break response of neurons and the therapeutic significance for neurodegenerative disease
Thu Aug 01 00:00:00 UTC 2013
MAPK Hog1 closes the S. cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators.
Genes & development
Lee J,Reiter W,Dohnal I,Gregori C,Beese-Sims S,Kuchler K,Ammerer G,Levin DE
MA1-980 was used in immunoprecipitation and western blot to study the regulation of the Saccharomyces cerevisiae Fps1 glycerol channel by Hog1-mediated phosphorylation
Sun Dec 01 00:00:00 UTC 2013
Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex.
British journal of cancer
Giessrigl B,Schmidt WM,Kalipciyan M,Jeitler M,Bilban M,Gollinger M,Krieger S,Jäger W,Mader RM,Krupitza G
MA1-980 was used in western blot to study the roles of GPER and CDK6 in the mechanisms of fulvestrant resistance in ER-positive breast cancer cells
Tue Nov 12 00:00:00 UTC 2013
Amotl2 interacts with LL5β, localizes to podosomes and regulates postsynaptic differentiation in muscle.
Journal of cell science
Proszynski TJ,Sanes JR
MA1-980 was used in Chromatin immunoprecipitation to demonstrate a role for Amotl2 in synaptic maturation and support the involvement of podosomes in this process.
Wed May 15 00:00:00 UTC 2013
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.
Journal of cellular biochemistry
Chen S,Yu X,Lei Q,Ma L,Guo D
MA1-980 was used in western blot to study the mechanism by which Ubc9-mediated SUMOylation of ZHX1 modulates its stability and functional activity
Tue Oct 01 00:00:00 UTC 2013
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.
Journal of cellular biochemistry
Chen S,Yu X,Lei Q,Ma L,Guo D
MA1-980 was used in western blot to study the mechanism by which Ubc9-mediated SUMOylation of ZHX1 modulates its stability and functional activity
Tue Oct 01 00:00:00 UTC 2013
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.
Journal of cellular biochemistry
Chen S,Yu X,Lei Q,Ma L,Guo D
MA1-980 was used in western blot to study the mechanism by which Ubc9-mediated SUMOylation of ZHX1 modulates its stability and functional activity
Tue Oct 01 00:00:00 UTC 2013
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.
Journal of cellular biochemistry
Chen S,Yu X,Lei Q,Ma L,Guo D
MA1-980 was used in western blot to study the mechanism by which Ubc9-mediated SUMOylation of ZHX1 modulates its stability and functional activity
Tue Oct 01 00:00:00 UTC 2013
The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.
Journal of cellular biochemistry
Chen S,Yu X,Lei Q,Ma L,Guo D
MA1-980 was used in western blot to study the mechanism by which Ubc9-mediated SUMOylation of ZHX1 modulates its stability and functional activity
Tue Oct 01 00:00:00 UTC 2013
Regulation of the transcriptional activation of the androgen receptor by the UXT-binding protein VHL.
The Biochemical journal
Chen S,Chen K,Zhang Q,Cheng H,Zhou R
MA1-980 was used in immunoprecipitation and western blot to study the mechanism by which the UXT-binding protein VHL modulates androgen receptor transcriptional activation
Fri Nov 15 00:00:00 UTC 2013
Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2.
The Biochemical journal
Maurer E,Gütschow M,Stirnberg M
MA1-980 was used in Western Blotting to identify hepatocyte growth factor activator inhibitor type 2 displaying high inhibitory potential against matriptase-2 at the cell surface as well as in conditioned medium.
Fri Mar 15 00:00:00 UTC 2013
Overexpression of MRPS18-2 in Cancer Cell Lines Results in Appearance of Multinucleated Cells.
Acta naturae
Shevchuk Z,Yurchenko MY,Darekar SD,Holodnuka-Kholodnyuk I,Kashuba VI,Kashuba EV
MA1-980 was used in immunocytochemistry to discover that S18-2 overexpression results in immortalization and de-differentiation of primary rat embryonic fibroblasts
Tue Jan 01 00:00:00 UTC 2013
Glu-44 in the amino-terminal α-helix of yeast vacuolar ATPase E subunit (Vma4p) has a role for VoV1 assembly.
The Journal of biological chemistry
Okamoto-Terry H,Umeki K,Nakanishi-Matsui M,Futai M
MA1-980 was used in Western Blot to identify Glu-44 as one of the key functional residues for subunit interaction in the vacuolar-type ATPase stalk complex.
Fri Dec 20 00:00:00 UTC 2013
Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression.
Epigenetics & chromatin
Grzenda A,Leonard P,Seo S,Mathison AJ,Urrutia G,Calvo E,Iovanna J,Urrutia R,Lomberk G
MA1-980 was used in western blot to study the cell cycle role of HP1-gamma phosphorylation at Ser 83 by Aurora A
Fri Jul 05 00:00:00 UTC 2013
Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.
Journal of molecular signaling
Ritchie BJ,Smolski WC,Montgomery ER,Fisher ES,Choi TY,Olson CM,Foster LA,Meigs TE
MA1-980 was used in western blot to describe Galpha12:RhoGEF complex and Galpha13:RhoGEF complexes
Mon Mar 25 00:00:00 UTC 2013
Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.
The Journal of biological chemistry
Gleyzer N,Scarpulla RC
MA1-980 was used in western blot to study the activation of the PRC-dependent stress program by apoptosis and senescence and its role in the response to cellular dysfunction
Fri Mar 22 00:00:00 UTC 2013
Cohesin association to replication sites depends on rad50 and promotes fork restart.
Molecular cell
Tittel-Elmer M,Lengronne A,Davidson MB,Bacal J,François P,Hohl M,Petrini JHJ,Pasero P,Cobb JA
MA1-980 was used in Chromatin immunoprecipitation to study the function of cohesin in the maintenance of genome integrity during S phase.
Fri Oct 12 00:00:00 UTC 2012
Identification of prognostic biomarkers for glioblastomas using protein expression profiling.
International journal of oncology
Jung Y,Joo KM,Seong DH,Choi YL,Kong DS,Kim Y,Kim MH,Jin J,Suh YL,Seol HJ,Shin CS,Lee JI,Kim JH,Song SY,Nam DH
MA1-980 was used in immunohistochemistry - paraffin section to identify diagnostic and prognostic markers for glioblastoma
Sun Apr 01 00:00:00 UTC 2012
The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A.
Biology open
Moghe S,Jiang F,Miura Y,Cerny RL,Tsai MY,Furukawa M
MA1-980 was used in western blot to study the role of Aurora A kinase in the mechanism by which CUL3-KLHL18 regulates cell cycle entry
Wed Feb 15 00:00:00 UTC 2012
CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).
The Journal of biological chemistry
Zhao Y,Wang Y,Hu J,Zhang X,Zhang YW
MA1-980 was used in Western Blotting to identify the H component of CUTA as a novel BACE1-interacting protein that mediates the intracellular trafficking of BACE1 and the processing of amyloid precursor protein to Β-amyloid.
Fri Mar 30 00:00:00 UTC 2012
Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yu J,Deshmukh H,Payton JE,Dunham C,Scheithauer BW,Tihan T,Prayson RA,Guha A,Bridge JA,Ferner RE,Lindberg GM,Gutmann RJ,Emnett RJ,Salavaggione L,Gutmann DH,Nagarajan R,Watson MA,Perry A
MA1-980 was used in immunohistochemistry - paraffin section to identify survival-associated genomic biomarkers for malignant peripheral nerve sheath tumors.
Fri Apr 01 00:00:00 UTC 2011
Upregulation of equine matrix metalloproteinase 1 by bovine papillomavirus type 1 is through the transcription factor activator protein-1.
The Journal of general virology
Yuan Z,Gault EA,Campo MS,Nasir L
MA1-980 was used in Western Blotting to elucidate the mechanism by which bovine papillomavirus type 1 proteins regulate equine metalloproteinase 1 expression.
Tue Nov 01 00:00:00 UTC 2011
A dominant negative zebrafish Ahr2 partially protects developing zebrafish from dioxin toxicity.
PloS one
Lanham KA,Prasch AL,Weina KM,Peterson RE,Heideman W
MA1-980 was used in western blot to study the role of a dominant negative zebrafish Ahr2 in protecting zebrafish from dioxin toxicity
Mon Aug 27 00:00:00 UTC 2012
ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.
The American journal of pathology
Koo BH,Coe DM,Dixon LJ,Somerville RP,Nelson CM,Wang LW,Young ME,Lindner DJ,Apte SS
MA1-980 was used in western blot to characterize angiogenesis defects in ADAMTS9+/- mice
Mon Mar 01 00:00:00 UTC 2010
Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA.
Molecular and cellular biology
Lim KH,Brady DC,Kashatus DF,Ancrile BB,Der CJ,Cox AD,Counter CM
MA1-980 was used in immunocytochemistry and western blot to show that Aurora-A in conjunction with oncogenic Ras enhances transformed cell growth
Fri Jan 01 00:00:00 UTC 2010
Detection of protein-RNA complexes in Xenopus oocytes.
Methods (San Diego, Calif.)
Huber PW,Zhao WM
MA1-980 was used in immunoprecipitation to develop a method for detecting protein-RNA complexes in Xenopus oocytes
Sat May 01 00:00:00 UTC 2010
A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis.
PloS one
Lorestani A,Sheiner L,Yang K,Robertson SD,Sahoo N,Brooks CF,Ferguson DJ,Striepen B,Gubbels MJ
MA1-980 was used in Immunocytochemistry to study the role of membrane occupation and recognition nexus protein 1 using the relatively simple budding process of Toxoplasma gondii as a model.
Thu Aug 19 00:00:00 UTC 2010
Ribosomal protein L11 associates with c-Myc at 5 S rRNA and tRNA genes and regulates their expression.
The Journal of biological chemistry
Dai MS,Sun XX,Lu H
MA1-980 was used in ChIP assay and western blot to investigate the role of L11 in the regulation of c-Myc-driven transcription
Fri Apr 23 00:00:00 UTC 2010
Ribosomal protein L11 associates with c-Myc at 5 S rRNA and tRNA genes and regulates their expression.
The Journal of biological chemistry
Dai MS,Sun XX,Lu H
MA1-980 was used in ChIP assay and western blot to investigate the role of L11 in the regulation of c-Myc-driven transcription
Fri Apr 23 00:00:00 UTC 2010
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1.
The Journal of biological chemistry
Lausen J,Pless O,Leonard F,Kuvardina ON,Koch B,Leutz A
MA1-980 was used in Western Blotting to identify parts of the ubiquitinylation machinery as a cellular target downstream of the transcription factor Tal1 and provide novel insights into Tal1-regulated erythropoiesis.
Fri Feb 19 00:00:00 UTC 2010
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model.
Cell
Kota J,Chivukula RR,O'Donnell KA,Wentzel EA,Montgomery CL,Hwang HW,Chang TC,Vivekanandan P,Torbenson M,Clark KR,Mendell JR,Mendell JT
MA1-980 was used in Western Blotting to investigate the efficacy of a miRNA replacement therapy, using miR-26a, in hepatocellular carcinoma cells.
Fri Jun 12 00:00:00 UTC 2009
Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60.
Journal of cell science
Miyabe I,Morishita T,Shinagawa H,Carr AM
MA1-980 was used in Immunocytochemistry to study the role of Rad60 phosphorylation in the regulation of homologous recombination at stalled replication forks.
Thu Oct 15 00:00:00 UTC 2009
An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization.
Molecular and cellular biology
Huot ME,Brown CM,Lamarche-Vane N,Richard S
MA1-980 was used in immunocytochemistry to demonstrate that Sam68-deficient cells exhibit loss of cell polarity and cell migration
Wed Apr 01 00:00:00 UTC 2009
Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis.
Developmental dynamics : an official publication of the American Association of Anatomists
Hart DO,Santra MK,Raha T,Green MR
MA1-980 was used in western blot to study the interaction of Trf3 and Taf3 during early development and hematopoiesis in zebrafish
Thu Oct 01 00:00:00 UTC 2009
Classic and desmoplastic medulloblastoma: complete case reports and characterizations of two new cell lines.
Neuropathology : official journal of the Japanese Society of Neuropathology
Holthouse DJ,Dallas PB,Ford J,Fabian V,Murch AR,Watson M,Wong G,Bertram C,Egli S,Baker DL,Kees UR
MA1-980 was used in western blot to report on two cases of classic and desmoplastic medulloblastoma and the characterization of two new cell lines
Sat Aug 01 00:00:00 UTC 2009
Akt phosphorylates both Tsc1 and Tsc2 in Drosophila, but neither phosphorylation is required for normal animal growth.
PloS one
Schleich S,Teleman AA
MA1-980 was used in western blot to investigate the phosphorylation of Tsc1 and Tsc2
Fri Jul 17 00:00:00 UTC 2009
Regulatory mechanism of matrix metalloprotease-2 enzymatic activity by factor Xa and thrombin.
The Journal of biological chemistry
Koo BH,Park MY,Jeon OH,Kim DS
MA1-980 was used in western blot to discuss how factor Xa and thrombin regulate MMP-2 enzymatic activity
Fri Aug 28 00:00:00 UTC 2009
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Genes & development
Hu J,Zacharek S,He YJ,Lee H,Shumway S,Duronio RJ,Xiong Y
MA1-980 was used in immunoprecipitation to study the role of the WD40 protein FBW5 in promoting the ubiquitinylation of tumor suppresor protein TSC2
Tue Apr 01 00:00:00 UTC 2008
Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo.
American journal of physiology. Heart and circulatory physiology
O'Donnell JM,Fields A,Xu X,Chowdhury SA,Geenen DL,Bi J
MA1-980 was used in western blot to study the results of adenoviral SERCA1 gene transfer in Sprague-Dawley rat hearts.
Mon Dec 01 00:00:00 UTC 2008
A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Molecular and cellular biology
Hagan GN,Lin Y,Magnuson MA,Avruch J,Czech MP
MA1-980 was used in western blot to study the role of a Rictor-Myo1c complex in dynamic cortical actin events in 3T3-L1 adipocytes.
Tue Jul 01 00:00:00 UTC 2008
CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.
Molecular biology of the cell
Tominaga H,Maeda S,Hayashi M,Takeda S,Akira S,Komiya S,Nakamura T,Akiyama H,Imamura T
MA1-980 was used in Western blotting following immunoprecipitation to elucidate the role of CCAAT/enhancer-binding protein beta as a crucial cofactor in the promotion of osteoblast maturation by Runx2 and ATF4.
Mon Dec 01 00:00:00 UTC 2008
The secreted metalloprotease ADAMTS20 is required for melanoblast survival.
PLoS genetics
Silver DL,Hou L,Somerville R,Young ME,Apte SS,Pavan WJ
MA1-980 was used in Western Blotting to study the role of ADAMTS20 in melanoblast survival.
Fri Feb 29 00:00:00 UTC 2008
Relationship between EBV infection and expression of cellular proteins c-Myc, Bcl-2, and Bax in gastric carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B
Lima MA,Ferreira MV,Barros MA,Pardini MI,Ferrasi AC,Mota RM,Rabenhorst SH
MA1-980 was used in immunohistochemistry to study the relationship between EBV infection and expression of c-Myc, Bcl-2, and Bax in gastric carcinomas
Sun Jun 01 00:00:00 UTC 2008
HIF-dependent antitumorigenic effect of antioxidants in vivo.
Cancer cell
Gao P,Zhang H,Dinavahi R,Li F,Xiang Y,Raman V,Bhujwalla ZM,Felsher DW,Cheng L,Pevsner J,Lee LA,Semenza GL,Dang CV
MA1-980 was used in Western Blotting to challenge the paradigm that antioxidants diminish tumorigenesis primarily through decreasing DNA damage and mutations and provide significant support for a key antitumorigenic effect of diminishing HIF levels.
Sat Sep 01 00:00:00 UTC 2007
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2.
Molecular cell
Yang H,Minamishima YA,Yan Q,Schlisio S,Ebert BL,Zhang X,Zhang L,Kim WY,Olumi AF,Kaelin WG
MA1-980 was used in Immunoprecipitation to study the mechanism by which VHL tumour suppressor protein-defective renal carcinoma cells exhibit increased NF-kappaB activity.
Fri Oct 12 00:00:00 UTC 2007
Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis.
Liver international : official journal of the International Association for the Study of the Liver
Itatsu K,Zen Y,Ohira S,Ishikawa A,Sato Y,Harada K,Ikeda H,Sasaki M,Nimura Y,Nakanuma Y
MA1-980 was used in immunohistochemistry - paraffin section to analyze the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis
Thu Nov 01 00:00:00 UTC 2007
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
The Journal of cell biology
Brinkmann MM,Spooner E,Hoebe K,Beutler B,Ploegh HL,Kim YM
MA1-980 was used in Immunoprecipitation to determine the role of the interaction between the endoplasmic reticulum membrane protein UNC93B and toll-like receptors 3, 7, and 9 in TLR signalling.
Mon Apr 23 00:00:00 UTC 2007
The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network.
Journal of cell science
Bouschet T,Martin S,Kanamarlapudi V,Mundell S,Henley JM
MA1-980 was used in Immunocytochemistry-immunoflourescence to demonstrate that stimulation of the calcium-sensing receptor triggers plasma membrane ruffling, and study the mechanisms by which this is mediated.
Wed Aug 01 00:00:00 UTC 2007
Phenotypes developed in secretin receptor-null mice indicated a role for secretin in regulating renal water reabsorption.
Molecular and cellular biology
Chu JY,Chung SC,Lam AK,Tam S,Chung SK,Chow BK
MA1-980 was used in Immunocytochemistry to study the vasopressin-independent mechanisms that modulate the process of renal water reabsorption.
Sun Apr 01 00:00:00 UTC 2007
Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase.
Molecular and cellular biology
Jones N,Hardy WR,Friese MB,Jorgensen C,Smith MJ,Woody NM,Burden SJ,Pawson T
MA1-980 was used in western blot to study ShcD/Shc4 interactions with the MuSK receptor
Sun Jul 01 00:00:00 UTC 2007
Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.
Molecular genetics and metabolism
Arola AM,Sanchez X,Murphy RT,Hasle A,Li H,Elliott PM,McKenna WJ,Towbin JA,Bowles NE
MA1-980 was used in immunocytochemistry to investigate the contribution of PDLIM3 and MYOZ1 to dilated cardiomyopathy
Sun Apr 01 00:00:00 UTC 2007
DKC1 is a direct and conserved transcriptional target of c-MYC.
Biochemical and biophysical research communications
Alawi F,Lee MN
MA1-980 was used in western blot to investigate the relationship between DKC1 and c-MYC
Sat Nov 03 00:00:00 UTC 2007
The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.
The Journal of biological chemistry
De Nicola F,Bruno T,Iezzi S,Di Padova M,Floridi A,Passananti C,Del Sal G,Fanciulli M
MA1-980 was used in immunoprecipitation and western blot to show that Che-1 is a new Pin1 and HDM2 target and has a role in the cellular response to DNA damage
Fri Jul 06 00:00:00 UTC 2007
Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide.
The Journal of biological chemistry
Koo BH,Longpré JM,Somerville RP,Alexander JP,Leduc R,Apte SS
MA1-980 was used in western blot to examine the role of the ADAMTS9 propeptide in regulating its secretion and proteolytic activity
Fri Jun 01 00:00:00 UTC 2007
Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function.
Oncogene
Andrews P,He YJ,Xiong Y
MA1-980 was used in western blot to study the association between ubiquitin ligase cullin 7 binds and p53
Thu Aug 03 00:00:00 UTC 2006
GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing.
The Journal of neuroscience : the official journal of the Society for Neuroscience
von Arnim CA,Spoelgen R,Peltan ID,Deng M,Courchesne S,Koker M,Matsui T,Kowa H,Lichtenthaler SF,Irizarry MC,Hyman BT
MA1-980 was used in Immunocytochemistry to study the effects of Golgi-localised gamma-ear-containing ARF-binding 1 overexpression on the levels of beta-amyloid precursor protein C-terminal fragments.
Wed Sep 27 00:00:00 UTC 2006
A conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr motif in hepatitis C virus glycoprotein E2 is a determinant of CD81 binding and viral entry.
Journal of virology
Drummer HE,Boo I,Maerz AL,Poumbourios P
MA1-980 was used in Western Blot to study the functional role of a conserved G436WLAGLFY motif of E2.
Tue Aug 01 00:00:00 UTC 2006
A conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr motif in hepatitis C virus glycoprotein E2 is a determinant of CD81 binding and viral entry.
Journal of virology
Drummer HE,Boo I,Maerz AL,Poumbourios P
MA1-980 was used in Western Blot to study the functional role of a conserved G436WLAGLFY motif of E2.
Tue Aug 01 00:00:00 UTC 2006
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.
Molecular and cellular biology
Haque F,Lloyd DJ,Smallwood DT,Dent CL,Shanahan CM,Fry AM,Trembath RC,Shackleton S
MA1-980 was used in Immunocytochemistry to provide evidence of a physical nuclear-cytoskeletal connection that is likely to be a key mechanism in nuclear-cytoplasmic communication and regulation of nuclear position.
Mon May 01 00:00:00 UTC 2006
AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins.
Molecular and cellular biology
Spence HJ,McGarry L,Chew CS,Carragher NO,Scott-Carragher LA,Yuan Z,Croft DR,Olson MF,Frame M,Ozanne BW
MA1-980 was used in western blot determine the role of Krp1 in v-Fos-transformed rat fibroblast cells
Wed Feb 01 00:00:00 UTC 2006
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis.
Molecular and cellular biology
O'Donnell KA,Yu D,Zeller KI,Kim JW,Racke F,Thomas-Tikhonenko A,Dang CV
MA1-980 was used in western blot to show that that TFRC1 is a downstream target of c-Myc in models of B-cell lymphoma
Wed Mar 01 00:00:00 UTC 2006
Identification of multiple actin-binding sites in cofilin-phosphatase Slingshot-1L.
FEBS letters
Yamamoto M,Nagata-Ohashi K,Ohta Y,Ohashi K,Mizuno K
MA1-980 was used in Immunocytochemistry to play unique roles in the control of subcellular localization and F-actin-mediated activation of SSH1L.
Mon Mar 20 00:00:00 UTC 2006
Identification of multiple actin-binding sites in cofilin-phosphatase Slingshot-1L.
FEBS letters
Yamamoto M,Nagata-Ohashi K,Ohta Y,Ohashi K,Mizuno K
MA1-980 was used in Immunocytochemistry to play unique roles in the control of subcellular localization and F-actin-mediated activation of SSH1L.
Mon Mar 20 00:00:00 UTC 2006
MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10.
Blood
Nakagawa M,Hosokawa Y,Yonezumi M,Izumiyama K,Suzuki R,Tsuzuki S,Asaka M,Seto M
MA1-980 was used in Western Blot to examine the mechanism determining the localisation of MALT1.
Thu Dec 15 00:00:00 UTC 2005
Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.
Circulation research
Pyagay P,Heroult M,Wang Q,Lehnert W,Belden J,Liaw L,Friesel RE,Lindner V
MA1-980 was used in western blot to investigate injury-induced collagen triple helix repeat containing 1 expression
Fri Feb 04 00:00:00 UTC 2005
Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.
The EMBO journal
Soosairajah J,Maiti S,Wiggan O,Sarmiere P,Moussi N,Sarcevic B,Sampath R,Bamburg JR,Bernard O
MA1-980 was used in immunoprecipitation and western blot to identify and characterize an ADF/cofilin phosphoregulatory complex
Wed Feb 09 00:00:00 UTC 2005
Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.
The EMBO journal
Soosairajah J,Maiti S,Wiggan O,Sarmiere P,Moussi N,Sarcevic B,Sampath R,Bamburg JR,Bernard O
MA1-980 was used in immunoprecipitation and western blot to identify and characterize an ADF/cofilin phosphoregulatory complex
Wed Feb 09 00:00:00 UTC 2005
Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Goldstein AY,Jan YN,Luo L
MA1-980 was used in immunohistochemistry to report that Tumbleweed, Pavarotti, and their association are required for neuroblast proliferation in Drosophila
Tue Mar 08 00:00:00 UTC 2005
Functional analyses of melanocortin-4 receptor mutations identified from patients with binge eating disorder and nonobese or obese subjects.
The Journal of clinical endocrinology and metabolism
Tao YX,Segaloff DL
MA1-980 was used in immunocytochemistry to study the role of MC4R mutations in the pathogenesis of binge eating disorder.
Sat Oct 01 00:00:00 UTC 2005
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D.
Journal of cell science
Jansen S,Stefan C,Creemers JW,Waelkens E,Van Eynde A,Stalmans W,Bollen M
MA1-980 was used in immunocytochemistry to investigate the maturation of autotaxin
Fri Jul 15 00:00:00 UTC 2005
Distinct roles of EGF repeats for the Notch signaling system.
Experimental cell research
Sakamoto K,Chao WS,Katsube K,Yamaguchi A
MA1-980 was used in western blot to report that Notch1 forms homodimers via its EGF motifs
Sat Jan 15 00:00:00 UTC 2005
Characterization of the human GARP (Golgi associated retrograde protein) complex.
Experimental cell research
Liewen H,Meinhold-Heerlein I,Oliveira V,Schwarzenbacher R,Luo G,Wadle A,Jung M,Pfreundschuh M,Stenner-Liewen F
MA1-980 was used in immunoprecipitation and western blot to identify and characterize a Vps fifty-three tethering factor complex
Sun May 15 00:00:00 UTC 2005
Characterization of the human GARP (Golgi associated retrograde protein) complex.
Experimental cell research
Liewen H,Meinhold-Heerlein I,Oliveira V,Schwarzenbacher R,Luo G,Wadle A,Jung M,Pfreundschuh M,Stenner-Liewen F
MA1-980 was used in immunoprecipitation and western blot to identify and characterize a Vps fifty-three tethering factor complex
Sun May 15 00:00:00 UTC 2005
Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.
FEBS letters
Zhang J,Wang Y,Zhou Y,Cao Z,Huang P,Lu B
MA1-980 was used in immunocytochemistry, immunoprecipitation, and western blot to investigate the function of gametogenetin protein 1
Mon Jan 17 00:00:00 UTC 2005
Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.
FEBS letters
Zhang J,Wang Y,Zhou Y,Cao Z,Huang P,Lu B
MA1-980 was used in immunocytochemistry, immunoprecipitation, and western blot to investigate the function of gametogenetin protein 1
Mon Jan 17 00:00:00 UTC 2005
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.
The Journal of biological chemistry
Iwata A,Riley BE,Johnston JA,Kopito RR
MA1-980 was used in western blot to report that autophagy is induced by impaired ubiquitin proteasome system activity
Fri Dec 02 00:00:00 UTC 2005
Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation.
The Journal of biological chemistry
Cardinale A,Filesi I,Vetrugno V,Pocchiari M,Sy MS,Biocca S
MA1-980 was used in immunocytochemistry and western blot to determine where prion protein is converted into the abnormal scrapie isoform intracellularly
Fri Jan 07 00:00:00 UTC 2005
Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation.
The Journal of biological chemistry
Cardinale A,Filesi I,Vetrugno V,Pocchiari M,Sy MS,Biocca S
MA1-980 was used in immunocytochemistry and western blot to determine where prion protein is converted into the abnormal scrapie isoform intracellularly
Fri Jan 07 00:00:00 UTC 2005
Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin.
The Journal of biological chemistry
Torres VJ,Ivie SE,McClain MS,Cover TL
MA1-980 was used in western blot to characterize vacuolating cytotoxin from Helicobacter pylori
Fri Jun 03 00:00:00 UTC 2005
The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish.
Development (Cambridge, England)
Hashimoto H,Rebagliati M,Ahmad N,Muraoka O,Kurokawa T,Hibi M,Suzuki T
MA1-980 was used in Western Blot to study the role of antagonistic interactions between Charon and Nodal (Southpaw) in regions adjacent to Kupffer's vesicle in left-right patterning in zebrafish.
Thu Apr 01 00:00:00 UTC 2004
Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathway.
Molecular and cellular biology
Bose A,Robida S,Furcinitti PS,Chawla A,Fogarty K,Corvera S,Czech MP
MA1-980 was used in immunocytochemistry to study the role of Myo1c in the membrane fusion of GLUT4-containing vesicles with the adipocyte plasma membrane
Tue Jun 01 00:00:00 UTC 2004
A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium.
Developmental biology
Lin HH,Khosla M,Huang HJ,Hsu DW,Michaelis C,Weeks G,Pears C
MA1-980 was used in immunocytochemistry, immunoprecipitation, and western blot to propose a direct role for DdCdk8 in spore formation
Thu Jul 01 00:00:00 UTC 2004
EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.
The Journal of biological chemistry
Guilherme A,Soriano NA,Bose S,Holik J,Bose A,Pomerleau DP,Furcinitti P,Leszyk J,Corvera S,Czech MP
MA1-980 was used in immunocytochemistry to study the role of EHD2 and EHBP1 in coupling endocytosis to the actin cytoskeleton
Fri Mar 12 00:00:00 UTC 2004
Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female.
The Journal of clinical endocrinology and metabolism
Donohoue PA,Tao YX,Collins M,Yeo GS,O'Rahilly S,Segaloff DL
MA1-980 was used in immunocytochemistry to investigate the role of the melanocortin-4 receptor in obesity.
Mon Dec 01 00:00:00 UTC 2003
14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
The Journal of biological chemistry
Shumway SD,Li Y,Xiong Y
MA1-980 was used in western blot to study the role of 14-3-3beta in regulating the TSC2 tumor suppressor gene product tuberin
Fri Jan 24 00:00:00 UTC 2003
N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.
The Journal of biological chemistry
Wahl JK,Kim YJ,Cullen JM,Johnson KR,Wheelock MJ
MA1-980 was used in western blot to investigate N-cadherin processing by proteolysis and the formation of N-cadherin-catenin complexes
Fri May 09 00:00:00 UTC 2003
GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression.
The Journal of experimental medicine
Baker-LePain JC,Sarzotti M,Fields TA,Li CY,Nicchitta CV
MA1-980 was used in Immunoprecipitation to study the tissue restriction of GRP94 elicited protective immunity in a 4T1 mammary carcinoma model.
Mon Dec 02 00:00:00 UTC 2002
[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier.
The Journal of cell biology
Komada M,Soriano P
MA1-980 was used in Immunoprecipitation to indicate that betaIV-spectrin and ankyrin-G mutually stabilize the membrane protein cluster and the linked membrane cytoskeleton at AIS and NR.
Mon Jan 21 00:00:00 UTC 2002
Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast.
Virchows Archiv : an international journal of pathology
Selim AG,El-Ayat G,Wells CA
MA1-980 was used in immunohistochemistry - paraffin section to examine the similarity between apocrine cells and high-grade ductal carcinoma
Fri Nov 01 00:00:00 UTC 2002
Localization of Saccharomyces cerevisiae protein phosphatase 2A subunits throughout mitotic cell cycle.
Molecular biology of the cell
Gentry MS,Hallberg RL
MA1-980 was used in Western Blotting to study the cell cycle dynamics of the protein phosphatase 2A enzyme population.
Tue Oct 01 00:00:00 UTC 2002
Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic.
The Journal of cell biology
Brown FD,Rozelle AL,Yin HL,Balla T,Donaldson JG
MA1-980 was used in immunocytochemistry to show that PIP 5-kinase activity and PIP2 turnover are critical for trafficking through the Arf6 PM-endosomal recycling pathway
Mon Sep 03 00:00:00 UTC 2001
Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.
The Journal of biological chemistry
Hilairet S,Bélanger C,Bertrand J,Laperrière A,Foord SM,Bouvier M
MA1-980 was used in flow cytometry, immunocytochemistry, immunoprecipitation, and western blot to study oligomerization and localization of the calcitonin receptor-like receptor
Fri Nov 09 00:00:00 UTC 2001
Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.
The Journal of biological chemistry
Hilairet S,Bélanger C,Bertrand J,Laperrière A,Foord SM,Bouvier M
MA1-980 was used in flow cytometry, immunocytochemistry, immunoprecipitation, and western blot to study oligomerization and localization of the calcitonin receptor-like receptor
Fri Nov 09 00:00:00 UTC 2001
Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells.
The Journal of biological chemistry
Laferriere J,Houle F,Taher MM,Valerie K,Huot J
MA1-980 was used in western blot to study the roles of E-selectin and of stress-activated protein kinase-2 in modulating endothelial adhesion and transendothelial migration
Fri Sep 07 00:00:00 UTC 2001
PYK2 as a mediator of endothelin-1/G alpha 11 signaling to GLUT4 glucose transporters.
The Journal of biological chemistry
Park JG,Bose A,Leszyk J,Czech MP
MA1-980 was used in immunocytochemistry to identify proteins selectively tyrosine-phosphorylated in response to ET-1 but not insulin
Fri Dec 21 00:00:00 UTC 2001
Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization.
The Journal of biological chemistry
Kim S,Lee SH,Park D
MA1-980 was used in immunoprecipitation to show that the leucine zipper domain mediates the formation of betaPix-a homodimers
Fri Apr 06 00:00:00 UTC 2001
Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3.
The Journal of biological chemistry
Banno Y,Takuwa Y,Akao Y,Okamoto H,Osawa Y,Naganawa T,Nakashima S,Suh PG,Nozawa Y
MA1-980 was used in immunoprecipitation to report that phospholipase D contributes to the activation of PI3K and Akt stimulation of EDG3 receptor
Fri Sep 21 00:00:00 UTC 2001
Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion.
Oncogene
Johnston IM,Spence HJ,Winnie JN,McGarry L,Vass JK,Meagher L,Stapleton G,Ozanne BW
MA1-980 was used in Western Blotting to identify activator protein-1 regulated genes based upon their differential expression in 208F rat fibroblasts transformed by FBR-v-fos.
Thu Nov 09 00:00:00 UTC 2000
Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment.
The Journal of biological chemistry
Grewal T,Heeren J,Mewawala D,Schnitgerhans T,Wendt D,Salomon G,Enrich C,Beisiegel U,Jäckle S
MA1-980 was used in Immunocytochemistry to investigate the possible role of annexin VI in endocytosis and intracellular trafficking of low density lipoprotein and transferrin.
Fri Oct 27 00:00:00 UTC 2000
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Molecular cell
Ohta T,Michel JJ,Schottelius AJ,Xiong Y
MA1-980 was used in immunoprecipitation to investigate the interaction between ROC1 and cullin proteins
Thu Apr 01 00:00:00 UTC 1999
Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
The EMBO journal
Wang XZ,Harding HP,Zhang Y,Jolicoeur EM,Kuroda M,Ron D
MA1-980 was used in immunocytochemistry to demonstrate that Ire1 plays a role in multiple facets of the ER stress-response
Thu Oct 01 00:00:00 UTC 1998
A conditional allele of the novel repeat-containing yeast nucleoporin RAT7/NUP159 causes both rapid cessation of mRNA export and reversible clustering of nuclear pore complexes.
The Journal of cell biology
Gorsch LC,Dockendorff TC,Cole CN
MA1-980 was used in immunocytochemistry to study how Rat7p regulates nucleocytoplasmic export of mRNA
Mon May 01 00:00:00 UTC 1995
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.
Molecular and cellular biology
Evan GI,Lewis GK,Ramsay G,Bishop JM
MA1-980 was used in western blot to describe antibodies that can be used to quantitate p62c-myc in cells
Sun Dec 01 00:00:00 UTC 1985
