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Invitrogen
cGKII Polyclonal Antibody
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Product Details
PA5-52426
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human cGKII. Recombinant protein control fragment (Product #RP-102027).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2639732
Product Specific Information
Immunogen sequence: REYHLKELRE QLSKQTVAIA ELTEELQNKC IQLNKLQDVV HMQGGSPLQA SPDKVPLEVH RKTSGLVSLH SRRGAKAGVS AEPTTRTYDL NKPPEFSFEK ARVRKDSSEK KLITDALNKN QFLKRLDPQQ IKDMVE
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Target Information
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cGK 2; cGKII; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; testicular tissue protein Li 99
Gene Aliases: cGK2; cGKII; PRKG2; PRKGR2
UniProt ID: (Human) Q13237
Entrez Gene ID: (Human) 5593
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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