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Product Details
100-401-A21
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal sequence of mouse cKrox protein.
Conjugate
Form
Lyophilized
Concentration
85 mg/mL
Storage buffer
0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is directed against mouse cKrox. A BLAST analysis was used to suggest cross-reactivity with cKrox from mouse, human and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.
Target Information
ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-Krox; DKFZp686G01254; hcKrox; Krueppel-related zinc finger protein cKrox; RP11-307C12.9; T helper-inducing POZ/Krueppel factor; T-helper-inducing POZ/Krueppel-like factor; Vzinc finger and BTB domain containing 7B; Zfp-67; zinc finger and BTB domain containing 15; Zinc finger and BTB domain-containing protein 15; Zinc finger and BTB domain-containing protein 7B; Zinc finger protein 67; Zinc finger protein 67 homolog; Zinc finger protein 857B; Zinc finger protein Th-POK
Gene Aliases: c-KROX; CKROX; hcKROX; THPOK; ZBTB15; ZBTB7B; ZFP-67; ZFP67; ZNF857B
UniProt ID: (Human) O15156, (Mouse) Q64321
Entrez Gene ID: (Human) 51043, (Rat) 295248, (Mouse) 22724
DNA binding
protein binding
metal ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
nucleic acid binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
transcription from RNA polymerase II promoter
positive regulation of gene expression
regulation of CD4-positive, alpha-beta T cell differentiation
regulation of CD8-positive, alpha-beta T cell differentiation
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
multicellular organism development
ectoderm development
cell differentiation
transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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