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Exalpha
chx 10 (Visual system homeobox 2) (CT) Polyclonal Antibody
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Product Details
X1179P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Antibody raised against a recombinant protein corresponding to amino acids 264 to 361 derived from the C terminal of the human Chx10 protein conjugated to KLH.
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Rat or mouse retinal tissue lysate. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
This antibody detects a 46 kDa band in mouse and rat retinal tissue lysates by Western blot. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
Target Information
CHX10 encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C. elegans ceh-10 homeo domain containing homolog; ceh-10 homeo domain containing homolog; ceh-10 homeodomain containing homolog; Ceh-10 homeodomain-containing homolog; Homeobox protein CHX10; ocular retardation; Visual system homeobox 2
Gene Aliases: CHX10; Hox-10; HOX10; MCOP2; MCOPCB3; or; RET1; VSX2
UniProt ID: (Human) P58304, (Chicken) Q9IAL1, (Mouse) Q61412
Entrez Gene ID: (Human) 338917, (Chicken) 395536, (Mouse) 12677, (Rat) 171360
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
positive regulation of cell proliferation
negative regulation of cell proliferation
camera-type eye development
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
retinal bipolar neuron differentiation
retina morphogenesis in camera-type eye
visual perception
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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