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Bethyl Laboratories
eIF2B delta/EIF2B4 Polyclonal Antibody
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eIF2B delta/EIF2B4 Antibody (A302-982A) in IHC (P)
Detection of human eIF2B delta/EIF2B4 by immunohistochemistry. Samples: FFPE sections of human colon carcinoma and breast carcinoma. Antibody: Affinity purified rabbit anti-eIF2B delta/EIF2B4 (Product # A302-982A) (Lot 1) used at a dilution of 1:200 (1 µg/mL). Detection: DAB.
Product Details
A302-982A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 50 and 100 of human Eukaryotic Translation Initiation Factor 2B, Subunit 4 delta, 67kDa.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; eIF2B GDP-GTP exchange factor subunit delta; eukaryotic translation initiation factor 2B subunit 4 delta; eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; translation initiation factor eIF-2b delta subunit; Translation initiation factor eIF2B subunit delta
Gene Aliases: EIF-2B; EIF2B; EIF2B4; EIF2BD; EIF2Bdelta
UniProt ID: (Human) Q9UI10
Entrez Gene ID: (Human) 8890
ovarian follicle development
translational initiation
regulation of translation
response to heat
response to glucose
oligodendrocyte development
L-methionine biosynthetic process from methylthioadenosine
negative regulation of translational initiation in response to stress
myelination
response to peptide hormone
positive regulation of GTPase activity
negative regulation of translational initiation
cellular response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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