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Invitrogen
eIF6 Recombinant Rabbit Monoclonal Antibody (HL1758)
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Product Details
MA5-47171
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1758
Immunogen
Recombinant protein encompassing a sequence within the center region of human EIF6. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938243
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B(2)GCN homolog; B4 integrin interactor; CAB; eIF-6; eIF-6 {ECO:0000255|HAMAP-Rule:MF_03132}; EIF6; eukaryotic translation initiation factor 3A; Eukaryotic translation initiation factor 6; eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132}; integrin beta 4 binding protein; p27 beta-4 integrin-binding protein; p27(BBP)
Gene Aliases: 1110004P11; AA408895; b(2)gcn; CAB; eIF-6; EIF3A; EIF6; imc-415; ITGB4BP; itgb4bp4; OK/SW-cl.27; p27(BBP); p27BBP; si:ch211-239j9.6; wu:fc28a04; wu:ft88f05; zgc:56562
UniProt ID: (Human) P56537, (Rat) Q3KRD8, (Mouse) O55135, (Zebrafish) Q6ZM19
Entrez Gene ID: (Human) 3692, (Rat) 305506, (Mouse) 16418, (Zebrafish) 386850
ribosomal subunit export from nucleus
translational initiation
mature ribosome assembly
ribosomal large subunit biogenesis
translation
ribosome biogenesis
assembly of large subunit precursor of preribosome
maturation of 5.8S rRNA
maturation of LSU-rRNA
regulation of glycolytic process
response to insulin
gene silencing by miRNA
miRNA mediated inhibition of translation
regulation of fatty acid biosynthetic process
regulation of megakaryocyte differentiation
positive regulation of translation
regulation of reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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