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Product Details
68217-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2A3H6
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FNRSVDGPIR LPIVDKYKDM GTVVLGKLES GSICKGQQLV MMPNKHNVEV LGILSDDVET DTVAPGENLK IRLKGIEEEE ILPGFILCDP NNLCHSGRTF DAQIVIIEHK SIICPGYNAV LHIHTCIEEV EITALICLVD KKSGEKSKTR PRFVKQDQVC IARLRTAGTI CLETFKDFPQ MGRFTLRDEG KTIAIGKVLK LVPEKD
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eRF3a; Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; eukaryotic polypeptide chain release factor 3; G1 to phase transition 1; G1 to S phase transition protein 1; G1 to S phase transition protein 1 homolog; G1-to-S phase transition 1; G1-to-S transition GTP binding protein; guanine nucleotide regulatory protein
Gene Aliases: 551G9.2; AI314175; AI326449; AV307676; C79774; ERF3A; ETF3A; G1st; GSPT1; Gst-1; GST1
UniProt ID: (Human) P15170, (Mouse) Q8R050
Entrez Gene ID: (Human) 2935, (Rat) 24420, (Mouse) 14852
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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