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Invitrogen
gamma Adaptin Recombinant Rabbit Monoclonal Antibody (4U2C8)
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FIGURE: 1 / 7
gamma Adaptin Antibody (MA5-37896) in ICC/IF
Immunofluorescence analysis of gamma Adaptin was performed using 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.01% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with gamma Adaptin Recombinant Rabbit Monoclonal Antibody (ARC2440) (Product # MA5-37896) at 1:100 in 0.1% ... View More
Product Details
MA5-37896
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4U2C8
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 723-822 of human AP1G1 (O43747)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897816
Product Specific Information
Positive Samples: HeLa, 293T, HepG2, Mouse liver, Mouse brain, Rat liver, Rat brain
Immunogen sequence: RSNTNPSVTV ITIQASNSTE LDMTDFVFQA AVPKTFQLQL LSPSSSIVPA FNTGTITQVI KVLNPQKQQL RMRIKLTYNH KGSAMQDLAE VNNFPPQSWQ
Target Information
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adapter-related protein complex 1 subunit gamma-1; adaptor protein complex AP-1 gamma 1 subunit; Adaptor protein complex AP-1 subunit gamma-1; adaptor protein complex AP-1, gamma 1 subunit; adaptor-related protein complex 1 gamma 1 subunit; Adaptor-related protein complex 1 subunit gamma-1; adaptor-related protein complex 1, gamma 1 subunit; AP-1 complex subunit gamma-1; clathrin assembly protein complex 1 gamma large chain; Clathrin assembly protein complex 1 gamma-1 large chain; clathrin-associated/assembly/adaptor protein, large, gamma 1; gamma adaptin; Gamma-adaptin; Gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; Golgi adaptor HA1/AP1 adaptin subunit gamma-1; MGC18255; testicular tissue protein Li 21
Gene Aliases: AA409002; ADTG; AP1G1; AU041323; AW551707; CLAPG1; D8Ertd374e
UniProt ID: (Human) O43747, (Mouse) P22892
Entrez Gene ID: (Human) 164, (Mouse) 11765, (Rat) 171494
microtubule cytoskeleton organization
transport
intracellular protein transport
protein transport
vesicle-mediated transport
endosome to melanosome transport
positive regulation of natural killer cell degranulation
positive regulation of natural killer cell mediated cytotoxicity
Golgi to lysosome transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
melanosome organization
regulation of defense response to virus by virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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