Product References
SARS-CoV-2 infection alkalinizes the ERGIC and lysosomes through the viroporin activity of the viral envelope protein.
Journal of cell science
Wang WA,Carreras-Sureda A,Demaurex N
MA1-850 was used in Western Blot to conclude that the envelope protein acts as a proton channel in the ERGIC to mitigate the acidity of this intermediate compartment.
Wed Mar 15 00:00:00 UTC 2023
Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.
Nature communications
Freitas-Andrade M,Comin CH,Van Dyken P,Ouellette J,Raman-Nair J,Blakeley N,Liu QY,Leclerc S,Pan Y,Liu Z,Carrier M,Thakur K,Savard A,Rurak GM,Tremblay MÈ,Salmaso N,da F Costa L,Coppola G,Lacoste B
MA1-850 was used in Western Blotting to identify astroglial Hmgb1 as an important player in postnatal gliovascular maturation.
Wed Aug 16 00:00:00 UTC 2023
N-terminal proteoforms may engage in different protein complexes.
Life science alliance
Bogaert A,Fijalkowska D,Staes A,Van de Steene T,Vuylsteke M,Stadler C,Eyckerman S,Spirohn K,Hao T,Calderwood MA,Gevaert K
MA1-850 was used in Western Blotting to show that N-terminal proteoforms can be engaged in new interactions and/or lose several interactions compared with their canonical counterparts, thus further expanding the functional diversity of proteomes.
Tue Aug 01 00:00:00 UTC 2023
Astrocytes show increased levels of Ero1α in multiple sclerosis and its experimental autoimmune encephalomyelitis animal model.
The European journal of neuroscience
Samtleben S,Mina L,Yap MC,Branton WG,Yousuf MS,Tenorio G,Ballanyi K,Giuliani F,Kerr BJ,Power C,Simmen T
MA1-850 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot to show that Ero1α induction makes astrocytes vulnerable to oxidative stress in the MS and EAE pathologies.
Sat Oct 01 00:00:00 UTC 2022
Astrocytes show increased levels of Ero1α in multiple sclerosis and its experimental autoimmune encephalomyelitis animal model.
The European journal of neuroscience
Samtleben S,Mina L,Yap MC,Branton WG,Yousuf MS,Tenorio G,Ballanyi K,Giuliani F,Kerr BJ,Power C,Simmen T
MA1-850 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot to show that Ero1α induction makes astrocytes vulnerable to oxidative stress in the MS and EAE pathologies.
Sat Oct 01 00:00:00 UTC 2022
Electrofusion Stimulation Is an Independent Factor of Chromosome Abnormality in Mice Oocytes Reconstructed via Spindle Transfer.
Frontiers in endocrinology
Wang W,Shao S,Chen W,Wang W,Chuai Y,Li Y,Guo Y,Han S,Shu M,Wang Q,Zhang L,Shang W
MA1-850 was used in Immunohistochemistry to compare the effects of enucleation and electrofusion stimulation on maturation promoting factor activity, spindle morphology, γ-tubulin localization and chromosome arrangement in mice oocytes.
Fri Feb 11 00:00:00 UTC 2022
S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse.
eLife
Carreras-Sureda A,Abrami L,Ji-Hee K,Wang WA,Henry C,Frieden M,Didier M,van der Goot FG,Demaurex N
MA1-850 was used in Western Blotting to establish S-acylation as a critical regulator of ORAI1 channel trafficking and function at the IS and reveal that ORAI1 S-acylation enhances TCR recruitment to the synapse.
Thu Dec 16 00:00:00 UTC 2021
S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse.
eLife
Carreras-Sureda A,Abrami L,Ji-Hee K,Wang WA,Henry C,Frieden M,Didier M,van der Goot FG,Demaurex N
MA1-850 was used in Western Blotting to establish S-acylation as a critical regulator of ORAI1 channel trafficking and function at the IS and reveal that ORAI1 S-acylation enhances TCR recruitment to the synapse.
Thu Dec 16 00:00:00 UTC 2021
The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction.
Cell reports
Belalcazar HM,Hendricks EL,Zamurrad S,Liebl FLW,Secombe J
MA1-850 was used in Western Blot to stud the role of the lysine demethylase 5 (KDM5) family of histone demethylases impacts transcriptional programs to mediate synaptic structure and activity.
Tue Feb 16 00:00:00 UTC 2021
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance.
EBioMedicine
Liu Q,Borcherding NC,Shao P,Maina PK,Zhang W,Qi HH
Published figure using gamma Tubulin monoclonal antibody (Product # MA1-850) in Western Blot
Wed Jan 01 00:00:00 UTC 2020
Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores.
Nature communications
Mudumbi KC,Czapiewski R,Ruba A,Junod SL,Li Y,Luo W,Ngo C,Ospina V,Schirmer EC,Yang W
MA1-850 was used in Western Blotting to suggest that peripheral channel transport is the default mechanism that was adapted in evolution to include aspects of receptor-mediated central channel transport for directed trafficking of certain membrane proteins.
Mon May 04 00:00:00 UTC 2020
Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells.
Oncology reports
Ohmine S,Salisbury JL,Ingle J,Pettinato G,Haddox CL,Haddad T,Galanis E,Ikeda Y,D'assoro AB
MA1-850 was used in Immunohistochemistry-Immunofluorescence to propose that Aurora-A-targeted therapy could represent a promising prophylactic therapeutic strategy to decrease the likelihood of CIN and development of aggressive teratomas derived from hiPSCs.
Sun Apr 01 00:00:00 UTC 2018
Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor.
Scientific reports
Groenendyk J,Paskevicius T,Urra H,Viricel C,Wang K,Barakat K,Hetz C,Kurgan L,Agellon LB,Michalak M
MA1-850 was used in Western Blotting to identify a novel and unanticipated cyclosporine-dependent signalling pathway, with cyclosporine triggering direct activation of the unfolded protein response.
Mon Nov 12 00:00:00 UTC 2018
Phaseolus vulgaris Exerts an Inhibitory Effect on Platelet Aggregation through AKT Dependent Way.
Preventive nutrition and food science
Rodríguez-Azúa R,Quinteros EF,Olate-Briones A,Moore-Carrasco R
MA1-850 was used in Western Blotting to describe a novel property of the Phaseolus vulgaris: inhibition of thrombotic cardiovascular events.
Fri Jun 01 00:00:00 UTC 2018
Hypoxic stabilization of mRNA is HIF-independent but requires mtROS.
Cellular & molecular biology letters
Fortenbery GW,Sarathy B,Carraway KR,Mansfield KD
MA1-850 was used in Western Blot to suggest that hypoxic mRNA stabilization is independent of HIF transcriptional activity but requires mtROS.
Mon Dec 31 00:00:00 UTC 2018
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.
Circulation
Abu-Taha IH,Heijman J,Hippe HJ,Wolf NM,El-Armouche A,Nikolaev VO,Schäfer M,Würtz CM,Neef S,Voigt N,Baczkó I,Varró A,Müller M,Meder B,Katus HA,Spiger K,Vettel C,Lehmann LH,Backs J,Skolnik EY,Lutz S,Dobrev D,Wieland T
MA1850 was used in western blot to demonstrate that nucleoside diphosphate kinase-C suppresses cAMP formation in human heart failure
Tue Feb 28 00:00:00 UTC 2017
Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis.
Scientific reports
Wang WA,Liu WX,Durnaoglu S,Lee SK,Lian J,Lehner R,Ahnn J,Agellon LB,Michalak M
Wed Jul 19 00:00:00 UTC 2017
c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer.
Oncotarget
Maina PK,Shao P,Liu Q,Fazli L,Tyler S,Nasir M,Dong X,Qi HH
MA1850 was used in western blot to elucidate the regulation of PHF8 and KDM3A during neuroendocrine differentiation and castration-resistant prostate cancer
Tue Nov 15 00:00:00 UTC 2016
The novel function of JADE1S in cytokinesis of epithelial cells.
Cell cycle (Georgetown, Tex.)
Siriwardana NS,Meyer RD,Panchenko MV
MA1-850 was used in Western Blotting to identify a role for JADE1S in regulation of cytokinesis and suggest its function in the Aurora B kinase-mediated cytokinesis checkpoint.
Wed Jun 22 00:00:00 UTC 2016
Inhibitory effects of Cyperus digitatus extract on human platelet function in vitro.
Platelets
Fuentes E,Forero-Doria O,Alarcón M,Palomo I
MA1-850 was used in western blot to study the mechanisms of antiplatelet action of Cyperus digitatus
Thu Jun 30 00:00:00 UTC 2016
Substrate stiffness effect and chromosome missegregation in hIPS cells.
Journal of negative results in biomedicine
Acevedo-Acevedo S,Crone WC
MA1-850 was used in immunocytochemistry to discuss how culturing conditions affect the genomic stability of pluripotent stem cells
Fri Dec 18 00:00:00 UTC 2015
Topiramate Protects Pericytes from Glucotoxicity: Role for Mitochondrial CA VA in Cerebromicrovascular Disease in Diabetes.
Journal of endocrinology and diabetes
Patrick P,Price TO,Diogo AL,Sheibani N,Banks WA,Shah GN
MA1-850 was used in western blot to study the role for mitochondrial CA VA in cerebromicrovascular disease in diabetes and protection of pericytes from glucotoxicity by topiramate
Wed Sep 30 00:00:00 UTC 2020
TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.
Human molecular genetics
Yan S,Wang CE,Wei W,Gaertig MA,Lai L,Li S,Li XJ
MA1-850 was used in western blot to study the different pathological effects of mutant TDP-43 in murine neuronal and glial cells
Thu May 15 00:00:00 UTC 2014
Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.
BMC cancer
Zhou Z,Patel M,Ng N,Hsieh MH,Orth AP,Walker JR,Batalov S,Harris JL,Liu J
MA1-850 was used in Western Blotting to suggest that the synthetic lethality between PRKDC and MYC may be partly due to PRKDC-dependent modulation of MYC expression.
Sat Dec 13 00:00:00 UTC 2014
A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities.
Nutrients
Fuentes E,Alarcón M,Fuentes M,Carrasco G,Palomo I
MA1-850 was used in Western Blotting to examine the antiplatelet and antithrombotic activities of Eruca sativa Mill.
Fri Dec 12 00:00:00 UTC 2014
NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center.
The Journal of biological chemistry
Messaed C,Akoury E,Djuric U,Zeng J,Saleh M,Gilbert L,Seoud M,Qureshi S,Slim R
MA1-850 was used in Immunofluorescence to study the effect of NLRP7 mutations on peripheral blood mononuclear cell's ability to secrete IL-1β and TNF in response to LPS.
Fri Dec 16 00:00:00 UTC 2011
NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center.
The Journal of biological chemistry
Messaed C,Akoury E,Djuric U,Zeng J,Saleh M,Gilbert L,Seoud M,Qureshi S,Slim R
MA1-850 was used in Immunofluorescence to study the effect of NLRP7 mutations on peripheral blood mononuclear cell's ability to secrete IL-1β and TNF in response to LPS.
Fri Dec 16 00:00:00 UTC 2011
Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.
Human molecular genetics
Smith WW,Liu Z,Liang Y,Masuda N,Swing DA,Jenkins NA,Copeland NG,Troncoso JC,Pletnikov M,Dawson TM,Martin LJ,Moran TH,Lee MK,Borchelt DR,Ross CA
MA1-850 was used in immunohistochemistry to investigate the neuroprotective effect of synphilin-1 in the A53T alpha-synuclein transgenic mouse model
Tue Jun 01 00:00:00 UTC 2010
