Proteintech

gamma catenin Monoclonal Antibody (1A5D10)

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View all (45) gamma Catenin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

66445-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:4,000
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Product Specifications

Species Reactivity

Dog, Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1A5D10

Immunogen

gamma catenin Fusion Protein Ag1627 (396-745 aa encoded by BC011865)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LVNQLSVDD VNVLTCATGT LSNLTCNNSK NKTLVTQNSG VEALIHAILR AGDKDDITEP AVCALRHLTS RHPEAEMAQN SVRLNYGIPA IVKLLNQPNQ WPLVKATIGL IRNLALCPAN HAPLQEAAVI PRLVQLLVKA HQDAQRHVAA GTQQPYTDGV RMEEIVEGCT GALHILARDP MNRMEIFRLN TIPLFVQLLY SSVENIQRVA AGVLCELAQD KEAADAIDAE GASAPLMELL HSRNEGTATY AAAVLFRISE DKNPDYRKRV SVELTNSLFK HDPAAWEAAQ SMIPINEPYG DDLDATYRPM YSSDVPLDPL EMHMDMDGDY PIDTYSDGLR PPYPTADHML A (396-745 aa encoded by BC011865)

Target Information

JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735; plakoglobin

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Gene Aliases: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB

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UniProt ID: (Pig) Q8WNW3, (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257

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Entrez Gene ID: (Pig) 397592, (Dog) 480522, (Human) 3728, (Rat) 81679, (Mouse) 16480

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Function(s)
transcription coactivator activity signal transducer activity structural molecule activity structural constituent of cell wall protein binding protein kinase binding protein phosphatase binding protein homodimerization activity alpha-catenin binding cadherin binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cadherin binding involved in cell-cell adhesion nuclear hormone receptor binding
Process(es)
desmosome assembly cytoskeletal anchoring at plasma membrane signal transduction single organismal cell-cell adhesion cell migration adherens junction organization adherens junction assembly regulation of cell proliferation positive regulation of protein import into nucleus skin development detection of mechanical stimulus positive regulation of sequence-specific DNA binding transcription factor activity protein heterooligomerization endothelial cell-cell adhesion cellular response to indole-3-methanol bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction establishment of protein localization to plasma membrane positive regulation of canonical Wnt signaling pathway regulation of ventricular cardiac muscle cell action potential cell adhesion regulation of cell fate specification positive regulation of transcription from RNA polymerase II promoter ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication regulation of nucleic acid-templated transcription
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