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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • hnRNP A2B1 Antibodies

          Invitrogen

          hnRNP A2B1 Polyclonal Antibody

          Advanced Verification
          1 Reference
          View all (17) hnRNP A2B1 antibodies

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          Datasheet
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          Cite hnRNP A2B1 Polyclonal Antibody

          • Antibody Testing Data (4)
          • Advanced Verification (1)
          hnRNP A2B1 Antibody in Immunocytochemistry (ICC/IF)
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          hnRNP A2B1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          hnRNP A2B1 Antibody (PA5-30061) in ICC/IF

          hnRNP A2B1 Polyclonal Antibody detects hnRNP A2B1 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: hnRNP A2B1 protein stained by hnRNP A2B1 Polyclonal Antibody (Product # PA5-30061) diluted at 1:1,000. Blue: Hoechst 33342 staining. Scale bar = 10 µm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          hnRNP A2B1 Antibody in Immunocytochemistry (ICC/IF)
          hnRNP A2B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          hnRNP A2B1 Antibody in Western Blot (WB)
          hnRNP A2B1 Antibody in Western Blot (WB)
          hnRNP A2B1 Antibody

          Product Details

          PA5-30061

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:10,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human hnRNP A2B1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.75 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2547535

          Product Specific Information

          Recommended positive controls: 293T, A549, HeLa, HepG2, HCT116.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DKFZp779B0244; FLJ22720; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2 / hnRNP B1; hnRNP A2/B1; nuclear ribonucleoprotein particle A2 protein; OTTHUMP00000202465; OTTHUMP00000202466

          View more View less

          Gene Aliases: HNRNPA2; HNRNPA2B1; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; IBMPFD2; RNPA2; SNRPB1

          View more View less

          UniProt ID: (Human) P22626

          View more View less

          Entrez Gene ID: (Human) 3181

          View more View less

          Function(s)
          nucleotide binding RNA binding mRNA 3'-UTR binding protein binding miRNA binding single-stranded telomeric DNA binding poly(A) RNA binding pre-mRNA intronic binding N6-methyladenosine-containing RNA binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter mRNA splicing, via spliceosome mRNA processing mRNA export from nucleus gene expression primary miRNA processing negative regulation of mRNA splicing, via spliceosome RNA transport miRNA transport
          It has to be done as per old AB suggested Products section.
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