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Proteintech
iASPP Polyclonal Antibody
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Product Details
18590-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
iASPP Fusion Protein Ag13273 (481-829 aa encoded by BC064913)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody could both recognize unphosphorylated and phosphorylated iASPP.
Immunogen sequence: EGPVARPLS PTRLQPALPP EAQSVPELEE VARVLAEIPR PLKRRGSMEQ APAVALPPTH KKQYQQIISR LFHRHGGPGP GGPEPELSPI TEGSEARAGP PAPAPPAPIP PPAPSQSSPP EQPQSMEMRS VLRKAGSPRK ARRARLNPLV LLLDAALTGE LEVVQQAVKE MNDPSQPNEE GITALHNAIC GANYSIVDFL ITAGANVNSP DSHGWTPLHC AASCNDTVIC MALVQHGAAI FATTLSDGAT AFEKCDPYRE GYADCATYLA DVEQSMGLMN SGAVYALWDY SAEFGDELSF REGESVTVLR RDGPEETDWW WAALHGQEGY VPRNYFGLFP RVKPQRSKV (481-829 aa encoded by BC064913)
Target Information
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53), whereas ASPP1. and ASPP2. are activators of p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: inhibitor of apoptosis stimulating protein of p53; Inhibitor of ASPP protein; NFkB interacting protein 1; NFkB-interacting protein 1; PPP1R13B-like protein; ppp1r13l; Protein iASPP; protein phosphatase 1, regulatory (inhibitor) subunit 13 like; protein phosphatase 1, regulatory subunit 13 like; RelA-associated inhibitor; retinoic acid induced 4
Gene Aliases: AV260376; IASPP; NKIP1; PPP1R13BL; PPP1R13L; RAI; RAI4; wa3
UniProt ID: (Human) Q8WUF5, (Mouse) Q5I1X5
Entrez Gene ID: (Human) 10848, (Mouse) 333654, (Rat) 686781
negative regulation of transcription from RNA polymerase II promoter
cardiac right ventricle morphogenesis
ventricular cardiac muscle tissue development
transcription, DNA-templated
apoptotic process
post-embryonic development
embryonic camera-type eye development
multicellular organism growth
hair cycle
positive regulation of cell differentiation
multicellular organismal homeostasis
cardiac muscle contraction
cell-cell adhesion
regulation of signal transduction by p53 class mediator
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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