Proteintech

iPLA2 Polyclonal Antibody

iPLA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

iPLA2 Antibody (22030-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human small intestine tissue slide using 22030-1-AP ( iPLA2 antibody at dilution of 1:50 (under 40x lens).

iPLA2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

22030-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

iPLA2 Fusion Protein Ag16896 (1-343 aa encoded by BC036742)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MQFFGRLVN TFSGVTNLFS NPFRVKEVAV ADYTSSDRVR EEGQLILFQN TPNRTWDCVL VNPRNSQSGF RLFQLELEAD ALVNFHQYSS QLLPFYESSP QVLHTEVLQH LTDLIRNHPS WSVAHLAVEL GIRECFHHSR IISCANCAEN EEGCTPLHLA CRKGDGEILV ELVQYCHTQM DVTDYKGETV FHYAVQGDNS QVLQLLGRNA VAGLNQVNNQ GLTPLHLACQ LGKQEMVRVL LLCNARCNIM GPNGYPIHSA MKFSQKGCAE MIISMDSSQI HSKDPRYGAS PLHWAKNAEM ARMLLKRGCN VNSTSSAGNT ALHVAVMRNR FDCAIVLLTH GANA (1-343 aa encoded by BC036742)

Target Information

The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition.

Cell reports

Mahoney-Sanchez L,Bouchaoui H,Boussaad I,Jonneaux A,Timmerman K,Berdeaux O,Ayton S,Krüger R,Duce JA,Devos D,Devedjian JC

Tue Aug 23 00:00:00 UTC 2022

Calcium-independent phospholipase A2 inhibitor produces an analgesic effect in a rat model of neuropathic pain by reducing central sensitization in the dorsal horn.

Neurological research

Gwak YS,Chen G,Abdi S,Kim HK

Sun Aug 01 00:00:00 UTC 2021

Inhibitory Effects of Peroxidase from Foxtail Millet Bran on Colitis-Associated Colorectal Carcinogenesis by the Blockage of Glycerophospholipid Metabolism.

Journal of agricultural and food chemistry

Shan S,Wu C,Shi J,Zhang X,Niu J,Li H,Li Z

Wed Aug 05 00:00:00 UTC 2020

Inhibitory Effects of Peroxidase from Foxtail Millet Bran on Colitis-Associated Colorectal Carcinogenesis by the Blockage of Glycerophospholipid Metabolism.

Journal of agricultural and food chemistry

Shan S,Wu C,Shi J,Zhang X,Niu J,Li H,Li Z

Wed Aug 05 00:00:00 UTC 2020

Inhibitory Effects of Peroxidase from Foxtail Millet Bran on Colitis-Associated Colorectal Carcinogenesis by the Blockage of Glycerophospholipid Metabolism.

Journal of agricultural and food chemistry

Shan S,Wu C,Shi J,Zhang X,Niu J,Li H,Li Z

Wed Aug 05 00:00:00 UTC 2020

Inhibitory Effects of Peroxidase from Foxtail Millet Bran on Colitis-Associated Colorectal Carcinogenesis by the Blockage of Glycerophospholipid Metabolism.

Journal of agricultural and food chemistry

Shan S,Wu C,Shi J,Zhang X,Niu J,Li H,Li Z

Wed Aug 05 00:00:00 UTC 2020

[Clinical features of infantile neuroaxonal dystrophy and PLA2G6 gene testing].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

Lu Y,Liu CH,Wang Y

Sun Sep 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: 2-lysophosphatidylcholine acylhydrolase; 85 kDa calcium-independent phospholipase A2; 85/88 kDa calcium-independent phospholipase A2; CaI-PLA2; Group VI phospholipase A2; GVI PLA2; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA2-beta; neurodegeneration with brain iron accumulation 2; Palmitoyl-CoA hydrolase; Patatin-like phospholipase domain-containing protein 9; phospholipase A2, group VI (cytosolic, calcium-independent); PNPLA9

View more View less

Gene Aliases: BB112799; CaI-PLA2; GVI; INAD1; iPLA(2)beta; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PLA2G6; PLPLA9; PNPLA9

View more View less

UniProt ID: (Human) O60733, (Mouse) P97819

View more View less

Entrez Gene ID: (Human) 8398, (Mouse) 53357

View more View less

Function(s)

phospholipase A2 activity calmodulin binding hydrolase activity protein kinase binding ATP-dependent protein binding calcium-independent phospholipase A2 activity

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

iPLA2 Polyclonal Antibody

iPLA2 Antibody (22030-1-AP) in IHC (P)

Product Details

22030-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!