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Product Details
PA1-30151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Rat mGlurR2/3 residues 860-872 (NGREVVDSTTSSL)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1958342
Product Specific Information
PA1-30151 detects mGluR2 + mGluR3 from rat samples.
Sequence is 100% conserved between mGluR2 and mGluR3. Predicted to react with human and mouse.
Target Information
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glutamate receptor; M mGlu3; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 3; mGluR2; mGluR3
Gene Aliases: Gprc1b; Gprc1c; Grm2; Grm3; Mglur2; Mglur3
UniProt ID: (Rat) P31421, (Rat) P31422
Entrez Gene ID: (Rat) 24415, (Rat) 24416
Performance Guarantee
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