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Alomone Labs, LTD
mGluR6 (extracellular) Polyclonal Antibody
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Product Details
AGC-026-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)GQSDDSTRK(S)TGEE, corresponding to amino acid residues 368-381 of rat mGluR6, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate receptor; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 6; mGluR6
Gene Aliases: BC021919; CSNB1B; Gm3; GPRC1F; GRM6; mGlu6; MGLUR6; nerg1; nob2; nob3; nob4
UniProt ID: (Human) O15303, (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Human) 2916, (Rat) 24419, (Mouse) 108072
signal transduction
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
detection of light stimulus involved in visual perception
sensory perception of light stimulus
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import
G-protein coupled receptor signaling pathway
visual perception
response to stimulus
detection of visible light
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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