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Bioss
muscarinic Acetylcholine Receptor 1 Polyclonal Antibody
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FIGURE: 1 / 1
muscarinic Acetylcholine Receptor 1 Antibody (BS-1150R) in WB
L1 rat kidney lysates, L2 rat brain lysates probed (bs-1150R) Anti-ChRM1/Acetylcholine receptor(M1) Polyclonal, Unconjugated at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band and observed band size: 51 kD.
Product Details
BS-1150R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Goat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human muscarinic Acetylcholine Receptor 1, amino acids 321-420.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 1; AChR M1; cholinergic receptor; Cholinergic receptor, muscarin 1; cholinergic receptor, muscarinic 1; M1 mAChR; m1 muscarinic acetylcholine receptor protein; MGC30125; Muscarinic acetylcholine receptor M1
Gene Aliases: Chrm-1; CHRM1; HM1; M1; M1R
UniProt ID: (Human) P11229, (Mouse) P12657, (Rat) P08482
Entrez Gene ID: (Human) 1128, (Mouse) 12669, (Rat) 25229
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
neuromuscular synaptic transmission
sensory perception of chemical stimulus
regulation of locomotion
regulation of ion transport
positive regulation of ion transport
saliva secretion
cognition
positive regulation of intracellular protein transport
regulation of vascular smooth muscle contraction
cellular protein modification process
protein kinase C-activating G-protein coupled receptor signaling pathway
nervous system development
cell proliferation
positive regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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