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p41-ARCb Antibody (PA5-18047) in IHC (P)
Immunohistochemistry analysis of p41-ARCb in human thymus. Samples were incubated with p41-ARCb polyclonal antibody (Product # PA5-18047) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-18047
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (AYHSFLVEPISCH) corresponding to the N-terminus amino acids of ARPC1B (aa 2-15).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10979327
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin related protein 2/3 complex subunit 1B, 41kDa; actin related protein 2/3 complex, subunit 1B, 41kDa; Actin-related protein 2/3 complex subunit 1B; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; OTTHUMP00000206020; p41-ARC
Gene Aliases: ARC41; ARPC1B; p40-ARC; p41-ARC
UniProt ID: (Human) O15143
Entrez Gene ID: (Human) 10095
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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