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Alomone Labs, LTD
slo beta 2 (KCNMB2) Polyclonal Antibody
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FIGURE: 1 / 2
slo beta 2 (KCNMB2) Antibody (APC-034-200UL) in IHC
Expression of KCNMB2in rat hippocampus - Immunohistochemical staining of rat hippocampus using Anti-slo beta 2 (KCNMB2) Antibody (#APC-034). A. KCNMB2appears in the pyramidal layer (green). B. Staining of interneurons with mouse Anti-parvalbumin (PV, red). C. Confocal merge of KCNMB2and PV demonstrates presence of KCNMB2also in PV (GABA containing) cells (orange).
Product Details
APC-034-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RHDEKRNIYQKIRDHDLLD, corresponding to amino acid residues 14-32 of humanKCNMB2, Intracellular, N-terminal domain
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: big potassium channel beta subunit 2; BK channel beta subunit 2; BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel beta 2; Calcium-activated potassium channel subunit beta-2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; hbeta2; Hbeta3; hCG1646471; K(VCA)beta-2; large conductance calcium-activated potassium channel beta 2 subunit; large-conductance Ca2+-activated K+ channel beta2 subunit; Maxi K channel subunit beta-2; MaxiK channel beta 2 subunit; MaxiK channel beta-subunit 2; potassium channel subfamily M regulatory beta subunit 2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; Rbeta3; Slo-beta-2; Slo-beta2
Gene Aliases: Kcmb2; KCNMB2
UniProt ID: (Human) Q9Y691, (Rat) Q811Q0
Entrez Gene ID: (Human) 10242, (Rat) 294961
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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