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Alomone Labs, LTD
slo beta 3 (KCNMB3) (extracellular) Polyclonal Antibody
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FIGURE: 1 / 2
slo beta 3 (KCNMB3) (extracellular) Antibody (APC-068-200UL) in IHC (F)
Expression of KCNMB3 in rat hippocampus. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-slo beta 3 (KCNMB3) (extracellular) Antibody (#APC-068), (1:300), followed by goat Anti-rabbit-Alexa-488. A. Staining in the hippocampal CA3 region, showed immunoreactivity (green) in cortical neurons (arrows). B. Pre-incubation of the Antibody with slo beta 3 (KCNMB3) (extracellular)... View More
Product Details
APC-068-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)HYDEEAIRTNPK, corresponding to amino acid residues 134-145 of rat KCNMB3, Extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BK beta 3; Calcium-activated potassium channel subfamily M subunit beta-3; Calcium-activated potassium channel subunit beta-3; kcnmb3 {ECO:0000312|EMBL:BAF79924.1}; Maxi K channel subunit beta-3; potassium large conductance calcium-activated channel, subfamily M beta member 3; potassium large conductance calcium-activated channel, subfamily M, beta member 4; slobeta3 (KCNMB3)
Gene Aliases: EG435726; Gm5707; Kcnmb3
UniProt ID: (Rat) A7VL23
Entrez Gene ID: (Mouse) 100502876, (Rat) 310303
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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