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slo beta 4 (KCNMB4) Antibody (APC-061-200UL) in IHC (F)
Expression of KCNMB4in rat hippocampus and cortex - Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-slo beta 4 (KCNMB4) Antibody (#APC-061), (1:200), followed by goat- Anti-rabbit-AlexaFluor-488. A. KCNMB4staining (green)in rat hippocampal CA1 region is detected inapical dendrites (arrows) of pyramidal neurons from the pyramidal layer (PL). B. Staining in rat parietal cor... View More
Product Details
APC-061-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AKLRVSYEYTEAEDKS(C), corresponding to amino acid residues 2-17 of rat KCNMB4, Intracellular, N-terminal domain
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: big potassium channel beta subunit 4; BK channel beta subunit 4; BK channel subunit beta-4; BKbeta4; calcium activated potassium channel beta 4 subunit; Calcium-activated potassium channel subunit beta-4; Calcium-activated potassium channel, subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; hbeta4; K(VCA)beta-4; KCMB4; large conductance calcium-dependent potassium ion channel beta 4 subunit; Maxi K channel subunit beta-4; MaxiK channel beta-subunit 4; potassium channel subfamily M regulatory beta subunit 4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; Slo-beta-4; Slowpoke beta 4
Gene Aliases: 1700058G18Rik; 2900045G12Rik; KCNMB4
UniProt ID: (Human) Q86W47, (Rat) Q9ESK8, (Mouse) Q9JIN6
Entrez Gene ID: (Human) 27345, (Rat) 66016, (Mouse) 58802
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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