Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TAGLN Antibodies

          Proteintech

          transgelin/SM22 Polyclonal Antibody

          120 References
          View all (38) TAGLN antibodies

          Promotion

          View available promotion(s)

          Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite transgelin/SM22 Polyclonal Antibody

          • Antibody Testing Data (13)
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 13

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          transgelin/SM22 Antibody (10493-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 10493-1-AP (transgelin/SM22 antibody) at dilution of 1:400 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          transgelin/SM22 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          transgelin/SM22 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          transgelin/SM22 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          transgelin/SM22 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          transgelin/SM22 Antibody in Western Blot (WB)
          transgelin/SM22 Antibody in Western Blot (WB)
          transgelin/SM22 Antibody in Western Blot (WB)

          Product Details

          10493-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 71 publications 71 publications

          Immunohistochemistry (IHC)

          -
          View 13 publications 13 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 33 publications 33 publications

          Flow Cytometry (Flow)

          Assay-dependent
          View 1 publication 1 publication

          Miscellaneous PubMed (MISC)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          transgelin/SM22 Fusion Protein Ag0764 (1-201 aa encoded by BC004927)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.23 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody was generated against full length transgelin 1 protein. It can cross-react with other two transgelins based on the sequence similarity.

          Immunogen sequence: MANKGPSYG MSREVQSKIE KKYDEELEER LVEWIIVQCG PDVGRPDRGR LGFQVWLKNG VILSKLVNSL YPDGSKPVKV PENPPSMVFK QMEQVAQFLK AAEDYGVIKT DMFQTVDLFE GKDMAAVQRT LMALGSLAVT KNDGHYRGDP NWFMKKAQEH KREFTESQLQ EGKHVIGLQM GSNRGASQAG MTGYGRPRQI IS (1-201 aa encoded by BC004927)

          Target Information

          TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 22 kDa actin-binding protein; Actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; sm22 alpha; SM22-alpha; Sm22alpha; smooth muscle 22 protein; Smooth muscle protein 22-alpha; Transgelin; transgelin variant 2

          View more View less

          Gene Aliases: SM22; Sm22a; SMCC; TAGLN; TAGLN1; WS3-10; Ws310

          View more View less

          UniProt ID: (Human) Q01995, (Rat) P31232, (Mouse) P37804

          View more View less

          Entrez Gene ID: (Human) 6876, (Rat) 25123, (Mouse) 21345

          View more View less

          Function(s)
          actin binding protein binding protein binding, bridging actin filament binding
          Process(es)
          cytoskeleton organization epithelial cell differentiation muscle organ development
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-67c77f6dc7-n6nf2:80/100.66.135.186:80.
          git-commit: 545e792480003146e539d624bd2a21b51d198228
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0