Identify, quantify and verify materials—from incoming inspection through finished product

To ensure product quality and consumer safety, pharmaceutical and biotechnology manufacturers must verify materials throughout production. The Thermo Scientific TruScan RM Handheld Analyzer uses lab-proven Raman spectroscopy to perform accurate and reliable material identification at the point of need, minimizing the need for costly and time-consuming laboratory sampling tests.

The analyzer’s non-destructive point-and-shoot sampling principle facilitates rapid verification of a broad range of chemical compounds through sealed packaging to minimize the risk of contamination and exposure.

QA/QC applications:

  • Incoming raw material identification (RMID)
  • Dispensing of materials during API manufacture
  • Finished product inspection

Brand security application:

  • Identification of falsified (counterfeit) medicines

Improve productivity and efficiency, minimize lab sampling with TruScan Handheld Raman Analyzers:
 

TruScan RM ROI
Raman spectroscopy

Raman spectroscopy

The technology behind TruScan Handheld Raman Analyzers is Raman spectrometry, a type of vibrational spectroscopy that characterizes materials based on measured patterns of vibrational frequencies, or wavelengths. The analyzer emits a laser light at 785nm and detects scattered photons at other wavelengths. The scattered light is a unique fingerprint for that material, and TruScan Handheld Raman Analyzers uses this "spectral fingerprint" to identify raw material or finished drug products. The 785nm laser wavelength provides optimal balance for measuring most pharmaceutical materials without compromising spectral resolution or Raman signal intensity.

Patented chemometrics engine

Patented chemometrics engine

The TruScan Handheld Raman Analyzers patented multivariate residual analysis offers the most effective chemometric solution for material identification—with two spectral pre-processing options—that is easy to operate in challenging environments and sampling conditions.

The TruScan Handheld Raman Analyzers acquires the Raman spectrum of the material and, in real time, determines the uncertainty of that measurement, given factors such as the sample characteristics, instrument telemetry, environment and testing environment. Since the software models the uncertainty (or in statistical terms, standard deviation) directly, there is no calibration or user modeling involved with method development.

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On-demand webinars for biotech process monitoring
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Watch on-demand webinars for biotech process monitoring

Breakthrough technologies and applications that are making pharmaceutical and biopharmaceutical processes more efficient.

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Improve on-site processes

Improve on-site processes
 

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Improve pharma and biotech manufacturing processes and help ensure patient safety

Improve pharma and biotech manufacturing processes

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Truscan App Note

TruScan RM Handheld Raman Analyzer for identification of cell culture media

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Featured video: TruScan RM Handheld Raman Analyzer with TruTools Chemometrics

Learn how the TruScan RM analyzer becomes a more powerful spectrometer with the TruTools chemometrics capability, which enables users to build custom models to be deployed on the analyzer for materials analysis at the point of need.


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