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One Lambda MagSort isolates specific HLA Antibodies using magnetic bead panels to adsorb and elute targeted antibodies.

One Lambda™ MagSort™ addresses emerging interests and challenges in adsorption and elution techniques for HLA antibody testing. Targeting individual HLA antigens enables a more focused dataset, to explore and define complex HLA antibody profiles at the antigen-specific level. This novel technology streamlines the process, reducing hands-on time for the laboratory staff, and standardizes a unique isolation approach compared to more cumbersome cell-based approaches.


Capabilities

Targeted technology

  • Individual antigen-coated magnetic beads
  • Elute antibodies that bind to a specific antigen
  • Results in a more focused HLA antibody assessment 

Customizable panels  

  • 59 antigens across 6 locus specific kits
  • Flexibility to focus only on antigens of interest
  • Coverage across well-documented antigens

Efficient workflow 

  • Up to 45 minutes of hands-on time and as little as 4 hours to      workflow completion
  • Uses equipment already found in most laboratories
  • Immediate antigen availability.

How does it work?

MagSort Workflow
MagSort example of results before and after isolating A*02:01

Products & coverage

MagSort Class I HLA-A

MagSort Class I HLA-B

MagSort Class I HLA-C 

MagSort Class II HLA-DRB1  MagSort Class II HLA-DQ MagSort Class II HLA-DP

A*0101

B*0702

C*0102

DRB1*0101 DQB1*0201
DQA1*0201
DPB1*0101
DPA1*0103

A*0201

B*0801

C*0202

DRB1*0301

DQB1*0202
DQA1*0201
DPB1*0201
DPA1*0103

A*0301

B*1301

C*0303

DRB1*0401

DQB1*0301
DQA1*0201
DPB1*0301
DPA1*0103

A*1101

B*1501

C*0304

DRB1*0404

DQB1*0302
DQA1*0201
DPB1*0401
DPA1*0103

A*2402

B*4402

C*0401

DRB1*0701

DQB1*0303
DQA1*0201
DPB1*0402
DPA1*0103

A*2501

B*4601

C*0501

DRB1*0801

DQB1*0401
DQA1*0201
DPB1*1101
DPA1*0103
A*2901 B*5301 C*0702 DRB1*1101 DQB1*0501
DQA1*0101
DPB1*1701
DPA1*0201
A*3001 B*5701 C*1203 DRB1*1201 DQB1*0602
DQA1*0101
DPB1*1901
DPA1*0103
A*3303 B*6701 C*1502 DRB1*1301 DQB1*0603
DQA1*0103
 
A*6801 B*7301 C*1601 DRB1*1501    
    C*1701 DRB1*1601    

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