Discriminate between povidone and crospovidone in under a minute.

The Thermo Scientific^™ TruScan^™ RM handheld Raman analyzer’s built-in multivariate residual analysis decision engine can identify the majority of pharmaceutical materials directly.

When characterizing structural analogs as similar as povidone and crospovidone, building individualized chemometric models to further enhance specificity is necessary.

Thermo Scientific TruTools^™ on-board chemometrics software provides:

• Advanced preprocessing of spectra
  
• Qualitative discrimination
• Quantitative component analysis
• Customized chemometric models including PCA, PLS, and PLSDA

In this application a TruScan RM with TruTools method provides qualitative results capable of discriminating between povidone and crospovidone.

Download our free application note, Discrimination of Povidone and Crospovidone Using a Handheld Raman Analyzer with On-board Chemometrics to learn more.