CTS™ KnockOut™ SR XenoFree Medium
CTS™ KnockOut™ SR XenoFree Medium
Gibco™

CTS™ KnockOut™ SR XenoFree Medium

Gibco CTS KnockOut SR XenoFree Medium, when formulated as a complete medium, enables the growth and expansion of human embryonicRead more
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Catalog NumberQuantity
12618013500 mL
12618012100 mL
Catalog number 12618013
Price (USD)
750.00
Each
Add to cart
Quantity:
500 mL
Price (USD)
750.00
Each
Add to cart

Gibco CTS KnockOut SR XenoFree Medium, when formulated as a complete medium, enables the growth and expansion of human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC) in a cell culture medium containing only human-derived or human recombinant proteins, to facilitate the transition of hESC and hiPSC research from the bench to the clinic.

The CTS product line enables you to reduce your burden in qualifying reagents during your transition from research applications to clinical applications.

CTS KnockOut SR XenoFree Medium does not contain bovine or other non-human, animal-derived components. Besides pluripotent stem cell culture expansion and maintenance, CTS KnockOut SR XenoFree Medium can be used for hESC⁄hiPSC cryopreservation, derivation, and differentiation studies.

Gibco CTS products are of high quality, and are supplied with harmonized documentation such as Certificates of Analysis, Certificates of Origin, and access to authorization letters for our Drug Master Files, as appropriate.

For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.
Specifications
Cell TypeEmbryonic Stem Cells (ESCs), Induced Pluripotent Stem Cells (iPSCs)
ClassificationXeno-free
FormLiquid
Product TypeCell Culture Supplement
Serum LevelSerum-free
SterilitySterile-filtered
FormatBottle
For Use With (Application)Cell and Gene Therapy Research, Development, and Manufacturing
Green FeaturesSustainable packaging
Manufacturing QualityISO 13485, MDSAP, FDA-registered, 21 CFR 820
Quantity500 mL
Shipping ConditionDry Ice
Unit SizeEach
Contents & Storage
Store at –5 to –20°C and protect from light.

Frequently asked questions (FAQs)

What is CTS?

The Gibco Cell Therapy Systems (CTS) portfolio of cell and gene therapy products are GMP manufactured, safety tested, and backed by regulatory documentation to support your transition from discovery through clinical and commercial manufacturing. Through our CTS solutions, we are committed to helping customers streamline therapeutic development, minimize risk, and ease the burden on their quality systems. Learn more here.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Do you offer a medical device–grade of CTS KnockOut SR XenoFree Medium?

Yes, we do offer a Class II medical device–labeled CTS KnockOut SR XenoFree Medium in the USA and Canada only. Please contact us at custommedia@thermofisher.com to discuss if a medical device grade is required for your application.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

How do I characterize human embryonic stem ( ES) cells?

Human ES cells are generally characterized by their typical morphology (they grow as tightly packed clusters of small cells with high ratio of nucleus to cytoplasm); surface marker expression; RT-PCR detection of stem cell-specific gene expression (such as Oct3/4, Sox2, and Nanog); alkaline phosphatase staining, and telomerase activity assay. The most commonly used ES specific surface markers include stage-specific embryonic antigens SSEA-3 and SSEA-4 for human ES cells. Other ES-specific surface antigens also include TRA-1-60 and TRA-1-81. (Science 282:1145 (1998).

How are human embryonic stem (ES) cells derived?

Human ES cells are derived from human blastocyst inner cell masses, isolated by immunosurgery with rabbit antiserum to BeWO cells (a human trophoblast cell line) (Science 282:1145 (1998)).

What are ES cells?

Embryonic stem (ES) cells are derived from the early mammalian embryo and are capable of unlimited, undifferentiated proliferation in vitro while maintaining their potential to differentiate into a wide of range of adult tissues including germ cells. The pluripotency of the ES cells is normally demonstrated in vitro by inducing ES cells to differentiate into embryoid bodies and checking lineage-specific markers for differentiated cells in three body layers (endo, meso, and ectoderm), or injecting them into immunodeficient mice and determining the cell types produced in the teratomas.