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Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
Thermo Scientific Pierce Sulfo-EGS is a water-soluble crosslinker that contains amine-reactive sulfo-NHS-ester ends around a 12-atom spacer arm, which canRead more
Catalog number 21566
Price (USD)
215.00
Each
Price (USD)
215.00
Each
Thermo Scientific Pierce Sulfo-EGS is a water-soluble crosslinker that contains amine-reactive sulfo-NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.
Features of Sulfo-EGS:
• Reactive groups: sulfo-NHS ester (both ends)
• Reactive towards: amino groups (primary amines)
• Water-soluble; compare to EGS
• Membrane-impermeable, allowing for cell surface labeling
• Crosslinks formed are reversible at pH 8.5 using hydroxylamine for 3 to 6 hours at 37°C
• Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
Features of Sulfo-EGS:
• Reactive groups: sulfo-NHS ester (both ends)
• Reactive towards: amino groups (primary amines)
• Water-soluble; compare to EGS
• Membrane-impermeable, allowing for cell surface labeling
• Crosslinks formed are reversible at pH 8.5 using hydroxylamine for 3 to 6 hours at 37°C
• Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine-Amine
CleavableBy Hydroxylamine
DescriptionSulfo-EGS
Molecular Weight (g/mol)660.45
PEGylatedNo
Spacer Arm Length16.1 Å
Cell PermeabilityNo
Shipping ConditionAmbient
Product LinePierce™
Labeling MethodChemical Labeling
Crosslinker TypeHomobifunctional
Reactive MoietySulfo-NHS Ester
SpacerMedium (10 to 30 Å)
FormPowder
Quantity50 mg
SolubilityWater
FormatStandard
Water SolubleYes
Product TypeCrosslinker
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at -20°C.