Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
Thermo Scientific™

Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)

Thermo Scientific Pierce Sulfo-SMPB is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends ofRead more
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Catalog number 22317
Price (USD)
273.00
Each
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Price (USD)
273.00
Each
Add to cart
Thermo Scientific Pierce Sulfo-SMPB is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).

Features of Sulfo-SMPB:

• Reactive groups: sulfo-NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Extended chain length limits steric hindrance
• Non-cleavable
• Water-soluble (compare to SMPB)
• Membrane impermeable, allowing for cell surface labeling

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine-Sulfhydryl
CleavableNo
DescriptionSulfo-SMPB
Molecular Weight (g/mol)458.37
PEGylatedNo
Spacer Arm Length11.6 Å
Cell PermeabilityNo
Shipping ConditionAmbient
Product LinePierce™
Labeling MethodChemical Labeling
Crosslinker TypeHeterobifunctional
Reactive MoietyMaleimide, Sulfo-NHS Ester
SpacerMedium (10 to 30 Å)
FormPowder
Quantity50 mg
SolubilityWater
FormatStandard
Water SolubleYes
Product TypeCrosslinker
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at -20°C.

Frequently asked questions (FAQs)

Can you provide the shelf-life for Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)?

Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.