SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)
SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)
Thermo Scientific™

SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)

Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactiveRead more
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Catalog number 22329
Price (USD)
376.00
Each
Add to cart
Price (USD)
376.00
Each
Add to cart
Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Features of SIAB:

Reactive groups: NHS ester and iodoacetyl
Reactive toward: amino and sulfhydryl groups
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-SIAB
• Used to prepare stable enzyme-IgG conjugates
• Forms conjugates with liposomes

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
Sulfo-SIAB (sulfosuccinimidyl (4-iodoacetyl)aminobenzoate)
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine-Sulfhydryl
CleavableNo
DescriptionSIAB
Molecular Weight (g/mol)402.14
PEGylatedNo
Spacer Arm Length10.6 Å
Cell PermeabilityYes
Shipping ConditionAmbient
Product LinePierce™
Labeling MethodChemical Labeling
Crosslinker TypeHeterobifunctional
Reactive MoietyHaloacetyl, NHS Ester
SpacerMedium (10 to 30 Å)
FormPowder
Quantity50 mg
SolubilityDMF, DMSO
FormatStandard
Water SolubleNo
Product TypeCrosslinker
Unit SizeEach
Contents & Storage
Upon receipt store at 4°C protected from light.

Frequently asked questions (FAQs)

Can you provide the shelf-life for SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)?

SIAB (succinimidyl (4-iodoacetyl)aminobenzoate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.