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SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of aRead more
Catalog number 22363
Price (USD)
250.00
Each
Price (USD)
250.00
Each
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).
Features of SMPH:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
Features of SMPH:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine-Sulfhydryl
CleavableNo
DescriptionSMPH
Molecular Weight (g/mol)379.36
PEGylatedNo
Spacer Arm Length14.2 Å
Cell PermeabilityYes
Shipping ConditionAmbient
Product LinePierce™
Labeling MethodChemical Labeling
Crosslinker TypeHeterobifunctional
Reactive MoietyMaleimide, NHS Ester
SpacerMedium (10 to 30 Å)
FormSolid
Quantity50 mg
SolubilityDMF, DMSO
FormatStandard
Water SolubleNo
Product TypeCrosslinker
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at 4°C.