SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
Thermo Scientific™

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)

Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of aRead more
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Catalog number 22416
Price (USD)
306.00
Each
Add to cart
Price (USD)
306.00
Each
Add to cart
Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).

Features of SMPB:

Reactive groups: NHS ester and maleimide
Reactive towards: amino and sulfhydryl groups
• Extended chain analog of MBS
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Conjugates formed with SMPB are more stable in serum than SPDP conjugates

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine-Sulfhydryl
CleavableNo
DescriptionSMPB
Molecular Weight (g/mol)356.33
PEGylatedNo
Spacer Arm Length11.6 Å
Cell PermeabilityYes
Shipping ConditionAmbient
Product LinePierce™
Labeling MethodChemical Labeling
Crosslinker TypeHeterobifunctional
Reactive MoietyMaleimide, NHS Ester
SpacerMedium (10 to 30 Å)
FormPowder
Quantity50 mg
SolubilityDMF, DMSO
FormatStandard
Water SolubleNo
Product TypeCrosslinker
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at 4°C.

Frequently asked questions (FAQs)

Can you provide the shelf-life for SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)?

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.