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Pierce™ Traut's Reagent (2-iminothiolane)
Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains)Read more
Catalog number 26101
Price (USD)
212.00
Each
Price (USD)
212.00
Each
Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.
Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):
• Simple—one-step conversion of amines to sulfhydryls
• Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility
Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.
Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
• Soluble—preserves the original positive charge to preserve protein solubility
Related Products
Pierce™ SATA
Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):
• Simple—one-step conversion of amines to sulfhydryls
• Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility
Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.
Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
• Soluble—preserves the original positive charge to preserve protein solubility
Related Products
Pierce™ SATA
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
Label or DyeSulfhydryl Group
Label TypeConjugating Groups
Product LinePierce™
SpacerShort (<10 Å)
FormPowder
Quantity500 mg
SolubilityDMF, DMSO
Product TypeThiophilic Adsorption Kit
Unit SizeEach
Contents & Storage
Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature