CellInsight™ CX5 High Content Screening (HCS) Platform
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Thermo Scientific™

CellInsight™ CX5 High Content Screening (HCS) Platform

The Thermo Scientific™ CellInsight™ CX5 High Content Screening (HCS) Platform is a fast, simple-to operate, automated cellular imaging and analysisRead more
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Catalog number CX51110
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The Thermo Scientific™ CellInsight™ CX5 High Content Screening (HCS) Platform is a fast, simple-to operate, automated cellular imaging and analysis benchtop platform designed for quantitative microscopy. The CellInsight CX5 HCS Platform offers a cost effective, but powerful way to quickly automate quantitative cellular and subcellular imaging.

Features of the CellInsight CX5 HCS Platform

• Easy to Use—quickly build and optimize image-based assays with included Thermo Scientific™ HCS Studio™ Cell Analysis Software
• Flexible—designed to work with or without fluorescent labeling: The CellInsight CX5 HCS Platform can use transmitted light, as well as fluorescence, to allow users to focus on visible and/or fluorescent targets
• Affordable—automated high content imaging for all budgets
• High quality optics—Light sources, lenses, filters, and CCD detector from the top names in imaging. The five color light engine insures accuracy and stability of source lighting.
• Virtually maintenance–free operation due to state-of-the-art design and construction.
• Performance—scan and analyze a 96-well plate in under four minutes
• Compact—fits on a bench and is less than 2 ft. on all sides

Capabilities:

• Make intracellular to multicellular morphology measurements while measuring intensity of specific reporter molecules.
• Collect only the images and data you select and make multiple measurements per object, over time, if desired
• Measure subpopulations and reject undesired objects automatically
• Comprehensive pre-validated and user configurable image analysis without user scripting or programming
• Exploratory assay development tools and specific biology optimized tools built into the HCS Studio™ Cell Analysis Software
• Define biological thresholds for outputs based on control populations
• Ability to create multi-parameter gates from individual output measurements

Hardware and Software:

• Stable, reliable light source reduces variability, increases data quality, and decreases operating costs
• Fluorescence options which include near-IR wavelength and compatibility with many common fluorochromes and fluorescent proteins
• • Proprietary Thermo Scientific™ AccuFocus™ System is fast, yet flexible, for imaging cells, organelles, and low contrast targets
• Unique intelligent acQuisition (iQ) real time analysis feedback to optimize image collection and data quality
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization and analysis software package for novice to advanced users
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database
• Software output features image/data portability so results can be imported into third-party software for documentation
• Compatible with SBS standard microplates (6-1536 well) and slides

Compatible with Thermo Scientific™ Orbitor RS Plate Mover and other Thermo Scientific™ Laboratory Automation Solutions
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Product LineCellInsight
DescriptionCeLLInsight™ CX5 High Content Screening Platform with HCS Studio Cell Analysis Software and Store Express
For Use With (Equipment)Thermo Scientific™ Orbitor™ RS Plate Mover
ColorGreen, Blue, Near-Infrared, Far-Red, Red
Detection MethodBrightfield, Fluorescence
FormatSlide(s), 96-well plate, 384-well plate, 6-well plate, 1536-well plate, 8 wells, 24-well plate
High-throughput CompatibilityHigh-throughput Compatible, Multiplexing, Automated Protocols
Wavelength740⁄809, 560⁄607, 485⁄521, 386⁄440, 650⁄694
ObjectivesAdditional Objectives Available, Low and High NA, Single Position 2x-20x
OpticsCCD Camera, LED, solid-state 5-color light engine
Data OutputsJPG Files, TIFF Files, PNG Files, C01, BMP, BIN, PZFX, ICE, GIF Files, DIB, CSV, FCS 3.1, XLSX
Display24in High-resolution widescreen monitor
Memory8GB RAM
Operating SystemWindows 7
PCWindows 7™ 64-bit PC with quad core 3.7GHz processor, 8GB RAM, and 500GB Hard Drive
Software CompatibilityThermo Scientific™ Store™ Image and Database Management Software, Thermo Scientific™ HCS Studio™ Cell Analysis Software
Operating EnvironmentPermissible ambient temperature range during operation : + 18 deg C to + 25 deg C, Permissible relative humidity during operation (noncondensing): > 75% at 30 deg C
Dimensions41.4 cm (16.3 in) (W) x 37.2 cm (14.6 in) (H) x 59.4 cm (23.4 in) (D)
Weight (Metric)45 kg
Voltage120V
Wattage300 W
Unit SizeEach

Frequently asked questions (FAQs)

Who do I contact if I have issues with my CellInsight systems or ArrayScan System?

Contact Instrument Customer Services for any issues regarding the CellInsight systems and ArrayScan System. They can be reached at instrumentservices@thermofisher.com.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

For high-content analysis (HCA)/high-content screening (HCS), what are the main differences between the CellInsight CX5, CX7, and ArrayScan systems?

The basic differences are in the number of channels for excitation (5 versus 7), the ability to image in brightfield, widefield, and confocal, and the number of positions available on the objective turret. The CellInsight CX5 System is the most basic HCS system with illumination in 5 channels, imaging in brightfield and widefield, and a 1-position objective turret. The CellInsight CX7 System and ArrayScan System provide illumination in 7 channels, imaging in brightfield, widefield, and confocal, and either a 3-position (CX7) or 4-position objective turret (ArrayScan System). The ArrayScan System has the added option of live-cell imaging. For more information, go here (https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cellular-imaging/high-content-screening.html).

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.