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Tango™ MTNR1A-bla U2OS Cells
The Tango™ MTNR1A-bla U2OS cells contain the human Melatonin Receptor 1A (MTNR1A) linked to a TEV protease site and aRead more
Catalog number K1669
Price (USD)
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The Tango™ MTNR1A-bla U2OS cells contain the human Melatonin Receptor 1A (MTNR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ MTNR1A-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ MTNR1A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
The Tango™ MTNR1A-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ MTNR1A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberNM_005958.3
Assay EntryCell-based beta-arrestin recruitment
Cell StateDividing Cells
Cytoplasmic TailNative Tail
Detection MethodFluorescence
Gene SymbolMTNR1A
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™
Protein FamilyGPCR (G-Protein Coupled Receptors)
Quantity8 x 106 cells
ReadoutEnd Point
Reporter GeneBLA (Beta-Lactamase)
Target EntryMTNR1A
Cell LineU2OS
System TypeTango™
Druggable TargetGPCR
Unit SizeEach
Contents & Storage
K1669 Tango™ MTNR1A-bla U2OS cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ MTNR1A-bla U2OS cells
• Tango™ MTNR1A-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ MTNR1A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ MTNR1A-bla U2OS cells
• Tango™ MTNR1A-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ MTNR1A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.