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          • Home
          • › Search Tool
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          • › Hs00174103_m1
          See other CXCL8 GE Assays ›
          Gene Symbol:
          CXCL8
          Gene Name:
          C-X-C motif chemokine ligand 8
          Gene Aliases:
          GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
          Chromosome Location:
          Chr.4: 73740506 - 73743716 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00174103_m1
          Best Coverage
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          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information
          • Citations (86)

          Genomic Map

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          Assay Details

          Gene Symbol: CXCL8
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_000584.3 NP_000575.1 1 - 2 222 101
          GenBank mRNA AK131067.1 - 1 - 2 159 101
          AK311874.1 - 1 - 2 159 101
          BC013615.1 - 1 - 2 109 3882471 101
          BG497712.1 - 1 - 2 223 101
          BT007067.1 - 1 - 2 69 101
          CR542151.1 - 1 - 2 69 101
          M17017.1 - 1 - 2 159 101
          M26383.1 - 1 - 2 143 101
          Y00787.1 - 1 - 2 170 101
          Z11686.1 - 1 - 2 69 101

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          More Information


          Set Membership:

          Ambion siRNA available Amplicon length greater than or equal to 101 Immune Tolerance Network Mammalian Gene Collection Recommended Assay Homo sapiens Human Androgen Panel Human Chemokine Panel Human Immune Response Human NFkB Pathway Human Angiogenesis Inventoried MicroArray Quality Control (MAQC) Human_Immune Human_Nfkb Human_Angiogenesis Human_Androgen Human_Chemokine Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene CXCL8

          Panther Classification:

          Molecular Function -

          chemokine

          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          response to molecule of bacterial origin
          movement of cell or subcellular component
          chemotaxis
          inflammatory response
          immune response
          cell cycle arrest
          signal transduction
          G-protein coupled receptor signaling pathway
          negative regulation of cell proliferation
          calcium-mediated signaling
          regulation of cell adhesion
          neutrophil chemotaxis
          receptor internalization
          response to endoplasmic reticulum stress
          intracellular signal transduction
          PERK-mediated unfolded protein response
          neutrophil activation
          cellular response to fibroblast growth factor stimulus
          regulation of single stranded viral RNA replication via double stranded DNA intermediate
          negative regulation of G-protein coupled receptor protein signaling pathway
          positive regulation of angiogenesis
          embryonic digestive tract development
          induction of positive chemotaxis
          chemokine-mediated signaling pathway
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          positive regulation of neutrophil chemotaxis
          interleukin-8 receptor binding
          protein binding
          chemokine activity

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          Citations (86)

          IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells.
          Authors
          Boost KA, Sadik CD, Bachmann M, Zwissler B, Pfeilschifter J, Muhl H
          Journal
          Bmc Cancer - Page No 265 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          8 (2008)
          Product Usage
          -
          Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression.
          Authors
          Yang EV, Kim SJ, Donovan EL, Chen M, Gross AC, Webster Marketon JI, Barsky SH, Glaser R
          Journal
          Brain Behav Immun - Page No 267 (Sun Feb 01 00:00:00 EST 2009)
          Volume (Year)
          23 (2009)
          Product Usage
          -
          The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.
          Authors
          Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
          Journal
          Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 EDT 2009)
          Volume (Year)
          52 (2009)
          Product Usage
          -
          Role of hypoxia-inducible factor-1alpha in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes.
          Authors
          Ahn JK, Koh EM, Cha HS, Lee YS, Kim J, Bae EK, Ahn KS
          Journal
          Rheumatology (Oxford) - Page No 834 (Sun Jun 01 00:00:00 EDT 2008)
          Volume (Year)
          47 (2008)
          Product Usage
          -
          Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.
          Authors
          Summers SA, van der Veen BS, O'Sullivan KM, Gan PY, Ooi JD, Heeringa P, Satchell SC, Mathieson PW, Saleem MA, Visvanathan K, Holdsworth SR, Kitching AR
          Journal
          Kidney Int - Page No 1263 (Wed Dec 01 00:00:00 EST 2010)
          Volume (Year)
          78 (2010)
          Product Usage
          -
          Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.
          Authors
          Galamb O, Spisak S, Sipos F, Toth K, Solymosi N, Wichmann B, Krenacs T, Valcz G, Tulassay Z, Molnar B
          Journal
          Br J Cancer - Page No 765 (Tue Feb 16 00:00:00 EST 2010)
          Volume (Year)
          102 (2010)
          Product Usage
          -
          NSAID-induced antral ulcers are associated with distinct changes in mucosal gene expression.
          Authors
          Desai JC, Goo T, Fukata M, Sanyal S, Dikman A, Miller K, Cohen L, Brooks A, Wang Q, Abreu MT, Aisenberg J
          Journal
          Aliment Pharmacol Ther - Page No 71 (Wed Jul 01 00:00:00 EDT 2009)
          Volume (Year)
          30 (2009)
          Product Usage
          -
          The Human Cutaneous Squamous Cell Carcinoma Microenvironment Is Characterized by Increased Lymphatic Density and Enhanced Expression of Macrophage-Derived VEGF-C.
          Authors
          Moussai D, Mitsui H, Pettersen JS, Pierson KC, Shah KR, Suarez-Farinas M, Cardinale IR, Bluth MJ, Krueger JG, Carucci JA
          Journal
          J Invest Dermatol - Page No (Thu Sep 09 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Iodide-induced chemokines and genes related to immunological function in cultured human thyroid follicles in the presence of thyrotropin.
          Authors
          Yamazaki K, Tanigawa K, Suzuki K, Yamada E, Yamada T, Takano K, Obara T, Sato K
          Journal
          Thyroid - Page No 67 (Fri Jan 01 00:00:00 EST 2010)
          Volume (Year)
          20 (2010)
          Product Usage
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          Olive oil-based lipid emulsion's neutral effects on neutrophil functions and leukocyte-endothelial cell interactions.
          Authors
          Buenestado A, Cortijo J, Sanz MJ, Naim-Abu-Nabah Y, Martinez-Losa M, Mata M, Issekutz AC, Marti-Bonmati E, Morcillo EJ
          Journal
          Jpen J Parenter Enteral Nutr - Page No 286 (Sat Jul 01 00:00:00 EDT 2006)
          Volume (Year)
          30 (2006)
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          Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.
          Authors
          Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
          Journal
          Cancer Sci - Page No 958 (Thu May 01 00:00:00 EDT 2008)
          Volume (Year)
          99 (2008)
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          IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IkappaBzeta mRNA.
          Authors
          Dhamija S, Doerrie A, Winzen R, Dittrich-Breiholz O, Taghipour A, Kuehne N, Kracht M, Holtmann H
          Journal
          J Biol Chem - Page No 29165 (Fri Sep 17 00:00:00 EDT 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -
          Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function.
          Authors
          Sorrentino R, de Souza PM, Sriskandan S, Duffin C, Paul-Clark MJ, Mitchell JA
          Journal
          Br J Pharmacol - Page No 864 (Sun Jun 01 00:00:00 EDT 2008)
          Volume (Year)
          154 (2008)
          Product Usage
          -
          Calcium dependent and independent cytokine synthesis by air pollution particle-exposed human bronchial epithelial cells.
          Authors
          Sakamoto N, Hayashi S, Gosselink J, Ishii H, Ishimatsu Y, Mukae H, Hogg JC, van Eeden SF
          Journal
          Toxicol Appl Pharmacol - Page No 134 (Sat Dec 01 00:00:00 EST 2007)
          Volume (Year)
          225 (2007)
          Product Usage
          -
          Tissue Factor-Factor VIIa complex induces cytokine expression in coronary artery smooth muscle cells.
          Authors
          Demetz G, Seitz I, Stein A, Steppich B, Groha P, Brandl R, Schomig A, Ott I
          Journal
          Atherosclerosis - Page No 466 (Fri Oct 01 00:00:00 EDT 2010)
          Volume (Year)
          212 (2010)
          Product Usage
          -
          Alterations in intestinal fatty acid metabolism in inflammatory bowel disease.
          Authors
          Heimerl S, Moehle C, Zahn A, Boettcher A, Stremmel W, Langmann T, Schmitz G
          Journal
          Biochim Biophys Acta - Page No 341 (Wed Mar 01 00:00:00 EST 2006)
          Volume (Year)
          1762 (2006)
          Product Usage
          -
          Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta.
          Authors
          Karlsen JR, Borregaard N, Cowland JB
          Journal
          J Biol Chem - Page No 14088 (Fri May 07 00:00:00 EDT 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -
          Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.
          Authors
          Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
          Journal
          Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 EST 2005)
          Volume (Year)
          152 (2005)
          Product Usage
          -
          Role of Aspergillus fumigatus DvrA in host cell interactions and virulence.
          Authors
          Ejzykowicz DE, Solis NV, Gravelat FN, Chabot J, Li X, Sheppard DC, Filler SG
          Journal
          Eukaryot Cell - Page No 1432 (Fri Oct 01 00:00:00 EDT 2010)
          Volume (Year)
          9 (2010)
          Product Usage
          -
          N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response.
          Authors
          Buetler TM, Leclerc E, Baumeyer A, Latado H, Newell J, Adolfsson O, Parisod V, Richoz J, Maurer S, Foata F, Piguet D, Junod S, Heizmann CW, Delatour T
          Journal
          Mol Nutr Food Res - Page No 370 (Sat Mar 01 00:00:00 EST 2008)
          Volume (Year)
          52 (2008)
          Product Usage
          -
          Inhibition of 13-cis retinoic acid-induced gene expression of homeobox B7 by thalidomide.
          Authors
          Milanovic D, Maier P, Lohr F, Wenz F, Herskind C
          Journal
          Int J Cancer - Page No 1205 (Sat Sep 15 00:00:00 EDT 2007)
          Volume (Year)
          121 (2007)
          Product Usage
          -
          Gene expression profiling of human mesenchymal stem cells chemotactically induced with CXCL12.
          Authors
          Stich S, Haag M, Haupl T, Sezer O, Notter M, Kaps C, Sittinger M, Ringe J
          Journal
          Cell Tissue Res - Page No 225 (Fri May 01 00:00:00 EDT 2009)
          Volume (Year)
          336 (2009)
          Product Usage
          -
          Assessment of the U937 cell line for the detection of contact allergens.
          Authors
          Python F, Goebel C, Aeby P
          Journal
          Toxicol Appl Pharmacol - Page No 113 (Sun Apr 15 00:00:00 EDT 2007)
          Volume (Year)
          220 (2007)
          Product Usage
          -
          Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.
          Authors
          Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suarez-Farinas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG
          Journal
          Br J Dermatol - Page No 1092 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          159 (2008)
          Product Usage
          -
          Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro.
          Authors
          O'Neil JD, Owen TJ, Wood VH, Date KL, Valentine R, Chukwuma MB, Arrand JR, Dawson CW, Young LS
          Journal
          J Gen Virol - Page No 2833 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          89 (2008)
          Product Usage
          -
          Cigarette smoke-induced pulmonary endothelial dysfunction is partially suppressed by sildenafil.
          Authors
          Milara J, Juan G, Ortiz JL, Guijarro R, Losada M, Serrano A, Morcillo EJ, Cortijo J
          Journal
          Eur J Pharm Sci - Page No 363 (Thu Mar 18 00:00:00 EDT 2010)
          Volume (Year)
          39 (2010)
          Product Usage
          -
          Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.
          Authors
          Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
          Journal
          Clin Cancer Res - Page No (Mon Oct 25 00:00:00 EDT 2010)
          Volume (Year)
           (2010)
          Product Usage
          -
          Hyperglycemia and lipopolysaccharide decrease depression effect of interleukin 8 production by hypothermia: an experimental study with endothelial cells.
          Authors
          Noda A, Kinoshita K, Sakurai A, Matsumoto T, Mugishima H, Tanjoh K
          Journal
          Intensive Care Med - Page No 109 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          34 (2008)
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          CD34+ cells augment endothelial cell differentiation of CD14+ endothelial progenitor cells in vitro.
          Authors
          Krenning G, van der Strate BW, Schipper M, van Seijen XJ, Fernandes BC, van Luyn MJ, Harmsen MC
          Journal
          J Cell Mol Med - Page No 2521 (Sat Aug 01 00:00:00 EDT 2009)
          Volume (Year)
          13 (2009)
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          TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.
          Authors
          Lim DM, Narasimhan S, Michaylira CZ, Wang ML
          Journal
          Am J Physiol Gastrointest Liver Physiol - Page No G1172 (Tue Dec 01 00:00:00 EST 2009)
          Volume (Year)
          297 (2009)
          Product Usage
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          Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
          Authors
          Verbeke H, De Hertogh G, Li S, Vandercappellen J, Noppen S, Schutyser E, El-Asrar AA, Opdenakker G, Van Damme J, Geboes K, Struyf S
          Journal
          Hum Pathol - Page No 990 (Thu Jul 01 00:00:00 EDT 2010)
          Volume (Year)
          41 (2010)
          Product Usage
          -
          Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis.
          Authors
          Barnes MG, Aronow BJ, Luyrink LK, Moroldo MB, Pavlidis P, Passo MH, Grom AA, Hirsch R, Giannini EH, Colbert RA, Glass DN, Thompson SD
          Journal
          Rheumatology (Oxford) - Page No 973 (Sun Aug 01 00:00:00 EDT 2004)
          Volume (Year)
          43 (2004)
          Product Usage
          -
          The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin.
          Authors
          Song J, Jie C, Polk P, Shridhar R, Clair T, Zhang J, Yin L, Keppler D
          Journal
          Biochem Biophys Res Commun - Page No 175 (Fri Feb 03 00:00:00 EST 2006)
          Volume (Year)
          340 (2006)
          Product Usage
          -
          HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1beta and TNF-alpha: involvement of mitogen-activated protein kinases and protein kinase R.
          Authors
          Zheng JC, Huang Y, Tang K, Cui M, Niemann D, Lopez A, Morgello S, Chen S
          Journal
          J Neuroimmunol - Page No 100 (Sat Aug 30 00:00:00 EDT 2008)
          Volume (Year)
          200 (2008)
          Product Usage
          -
          Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.
          Authors
          Wurfel MM, Park WY, Radella F, Ruzinski J, Sandstrom A, Strout J, Bumgarner RE, Martin TR
          Journal
          J Immunol - Page No 2570 (Mon Aug 15 00:00:00 EDT 2005)
          Volume (Year)
          175 (2005)
          Product Usage
          -
          Leukocytes are primed in peripheral blood for activation during term and preterm labour.
          Authors
          Yuan M, Jordan F, McInnes IB, Harnett MM, Norman JE
          Journal
          Mol Hum Reprod - Page No 713 (Sun Nov 01 00:00:00 EDT 2009)
          Volume (Year)
          15 (2009)
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          Polarized response of endothelial cells to invasion by Aspergillus fumigatus.
          Authors
          Kamai Y, Lossinsky AS, Liu H, Sheppard DC, Filler SG
          Journal
          Cell Microbiol - Page No 170 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          11 (2009)
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          cis-Urocanic acid initiates gene transcription in primary human keratinocytes.
          Authors
          Kaneko K, Smetana-Just U, Matsui M, Young AR, John S, Norval M, Walker SL
          Journal
          J Immunol - Page No 217 (Tue Jul 01 00:00:00 EDT 2008)
          Volume (Year)
          181 (2008)
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          Macrophage-secreted factors inhibit ZAG expression and secretion by human adipocytes.
          Authors
          Gao D, Trayhurn P, Bing C
          Journal
          Mol Cell Endocrinol - Page No 135 (Mon Aug 30 00:00:00 EDT 2010)
          Volume (Year)
          325 (2010)
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          Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.
          Authors
          Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY
          Journal
          J Clin Endocrinol Metab - Page No 4065 (Wed Oct 01 00:00:00 EDT 2008)
          Volume (Year)
          93 (2008)
          Product Usage
          -
          Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells.
          Authors
          Hedvat CV, Yao J, Sokolic RA, Nimer SD
          Journal
          J Biol Chem - Page No 6395 (Fri Feb 20 00:00:00 EST 2004)
          Volume (Year)
          279 (2004)
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          Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.
          Authors
          Milara J, Mata M, Mauricio MD, Donet E, Morcillo EJ, Cortijo J
          Journal
          Eur J Pharmacol - Page No 132 (Fri May 01 00:00:00 EDT 2009)
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          609 (2009)
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          Gram-positive and Gram-negative bacteria synergize with oxidants to release CXCL8 from innate immune cells.
          Authors
          Paul-Clark MJ, Sorrentino R, Bailey LK, Sriskandan S, Mitchell JA
          Journal
          Mol Med - Page No 238 (Thu May 01 00:00:00 EDT 2008)
          Volume (Year)
          14 (2008)
          Product Usage
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          Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: implications in acute myocardial infarction.
          Authors
          Busch G, Seitz I, Steppich B, Hess S, Eckl R, Schomig A, Ott I
          Journal
          Arterioscler Thromb Vasc Biol - Page No 461 (Tue Feb 01 00:00:00 EST 2005)
          Volume (Year)
          25 (2005)
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          Angiogenic transcriptome of human microvascular endothelial cells: Effect of hypoxia, modulation by atorvastatin.
          Authors
          Loboda A, Jazwa A, Jozkowicz A, Molema G, Dulak J
          Journal
          Vascul Pharmacol - Page No 206 (Sat Apr 01 00:00:00 EST 2006)
          Volume (Year)
          44 (2006)
          Product Usage
          -
          Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10.
          Authors
          Christersson C, Johnell M, Siegbahn A
          Journal
          J Thromb Haemost - Page No 986 (Sun Jun 01 00:00:00 EDT 2008)
          Volume (Year)
          6 (2008)
          Product Usage
          -
          Differential expression patterns of cytokines in complex regional pain syndrome.
          Authors
          Uceyler N, Eberle T, Rolke R, Birklein F, Sommer C
          Journal
          Pain - Page No 195 (Thu Nov 01 00:00:00 EDT 2007)
          Volume (Year)
          132 (2007)
          Product Usage
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          Overexpression of the CXCL3 gene in response to oxidized low-density lipoprotein is associated with the presence of tendon xanthomas in familial hypercholesterolemia.
          Authors
          Martin-Fuentes P, Civeira F, Solanas-Barca M, Garcia-Otin AL, Jarauta E, Cenarro A
          Journal
          Biochem Cell Biol - Page No 493 (Mon Jun 01 00:00:00 EDT 2009)
          Volume (Year)
          87 (2009)
          Product Usage
          -
          Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept.
          Authors
          Koczan D, Drynda S, Hecker M, Drynda A, Guthke R, Kekow J, Thiesen HJ
          Journal
          Arthritis Res Ther - Page No R50 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          10 (2008)
          Product Usage
          -
          The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.
          Authors
          Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M
          Journal
          Plos One - Page No e4273 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          4 (2009)
          Product Usage
          -
          The synthetic melanocortin (CKPV)2 exerts broad anti-inflammatory effects in human neutrophils.
          Authors
          Capsoni F, Ongari A, Colombo G, Turcatti F, Catania A
          Journal
          Peptides - Page No 2016 (Mon Oct 01 00:00:00 EDT 2007)
          Volume (Year)
          28 (2007)
          Product Usage
          -
          Liver X receptor is a therapeutic target for photoaging and chronological skin aging.
          Authors
          Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins SF, Wang W, Wang Y, LaCava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S
          Journal
          Mol Endocrinol - Page No 2407 (Sat Nov 01 00:00:00 EDT 2008)
          Volume (Year)
          22 (2008)
          Product Usage
          -
          Selective regulation of MAP kinases and chemokine expression after ligation of ICAM-1 on human airway epithelial cells.
          Authors
          Krunkosky TM, Jarrett CL
          Journal
          Respir Res - Page No 12 (Sun Jan 01 00:00:00 EST 2006)
          Volume (Year)
          7 (2006)
          Product Usage
          -
          Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro.
          Authors
          Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC, Molema G
          Journal
          Am J Physiol Cell Physiol - Page No C1229 (Tue Nov 01 00:00:00 EST 2005)
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          289 (2005)
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          Hepatitis C virus proteins interfere with the activation of chemokine gene promoters and downregulate chemokine gene expression.
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          Sillanpaa M, Kaukinen P, Melen K, Julkunen I
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          89 (2008)
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          Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation.
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          Smythies LE, Shen R, Bimczok D, Novak L, Clements RH, Eckhoff DE, Bouchard P, George MD, Hu WK, Dandekar S, Smith PD
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          285 (2010)
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          Aeby P, Sieber T, Beck H, Gerberick GF, Goebel C
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          129 (2009)
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          Postmenopausal expression changes of immune system-related genes in human bone tissue.
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          Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P
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          29 (2009)
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          Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy.
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          Bodo E, Tobin DJ, Kamenisch Y, Biro T, Berneburg M, Funk W, Paus R
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          171 (2007)
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          Characterization of the innate immune signalling pathways in hepatocyte cell lines.
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          Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P
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          15 (2008)
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          18 (2009)
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          McHale CM, Zhang L, Hubbard AE, Zhao X, Baccarelli A, Pesatori AC, Smith MT, Landi MT
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          229 (2007)
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          13 (2008)
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          Kaneko T, Okiji T, Kaneko R, Suda H, Nor JE
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          72 (2009)
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          Tissieres P, Dunn-Siegrist I, Schappi M, Elson G, Comte R, Nobre V, Pugin J
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          111 (2008)
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          Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants.
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          10 (2008)
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          Sakamoto N, Hayashi S, Mukae H, Vincent R, Hogg JC, van Eeden SF
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          28 (2009)
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          32 (2009)
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          Gene expression profile of adult human bone marrow-derived mesenchymal stem cells stimulated by the chemokine CXCL7.
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          41 (2009)
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          39 (2009)
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          The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses.
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          184 (2010)
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          27 (2009)
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           (2010)
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          75 (2004)
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          8 (2006)
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          44 (2010)
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          Volume (Year)
          30 (2010)
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          Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF
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          81 (2007)
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          Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood.
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          Volume (Year)
          45 (2008)
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          Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
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          156 (2009)
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          238 (2009)
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          Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium.
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          Gabrielsen A, Lawler PR, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-Berne G, Kastrup J, Hansson GK
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          42 (2007)
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          Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
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          Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
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          Influenza Other Respi Viruses - Page No 139 (Sun Jul 01 00:00:00 EDT 2007)
          Volume (Year)
          1 (2007)
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          Social regulation of gene expression in human leukocytes.
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          Cole SW, Hawkley LC, Arevalo JM, Sung CY, Rose RM, Cacioppo JT
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          8 (2007)
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          -
          Transcriptional program induced by factor VIIa-tissue factor, PAR1 and PAR2 in MDA-MB-231 cells.
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          J Thromb Haemost - Page No 1588 (Wed Aug 01 00:00:00 EDT 2007)
          Volume (Year)
          5 (2007)
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