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          • Home
          • › Search Tool
          • › Search Results
          • › Hs00174143_m1
          See other IFNG GE Assays ›
          Gene Symbol:
          IFNG
          Gene Name:
          interferon gamma
          Gene Aliases:
          IFG, IFI
          Chromosome Location:
          Chr.12: 68154770 - 68159741 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00174143_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (31)

          Genomic Map

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          Assay Details

          Gene Symbol: IFNG
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_000619.2 NP_000610.2 1 - 2 246 79
          GenBank mRNA AB451324.1 - 1 - 2 120 79
          AB451453.1 - 1 - 2 120 79
          AF506749.1 - 1 - 2 54 79
          AM903379.1 - 1 - 2 133 79
          AY044154.1 - 1 - 2 51 79
          AY255837.1 - 1 - 2 120 79
          AY255839.1 - 1 - 2 54 79
          BC070256.1 - 1 - 2 248 30414644 79
          V00543.1 - 1 - 2 211 79
          X13274.1 - 1 - 2 228 79
          X87308.1 - 1 - 2 60 79

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC1200011177.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC12001696.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Apoptosis Immune Tolerance Network Mammalian Gene Collection Homo sapiens Human Androgen Panel Human Chemokine Panel Human TGFB Panel Human Immune Response Human Alzheimer's Disease Human Diabetes Human Angiogenesis Inventoried Human_Immune Human_Angiogenesis Human_Androgen Human_Diabetes Human_Chemokine Human_TGFB Human_Alzheimer Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene IFNG

          Panther Classification:

          Molecular Function -

          cytokine interferon superfamily intercellular signal molecule

          Gene Ontology Categories:

          Function(s) Process(es)

          protein import into nucleus, translocation
          negative regulation of transcription from RNA polymerase II promoter
          neutrophil apoptotic process
          regulation of the force of heart contraction
          adaptive immune response
          CD8-positive, alpha-beta T cell differentiation involved in immune response
          apoptotic process
          movement of cell or subcellular component
          humoral immune response
          cell cycle arrest
          cell surface receptor signaling pathway
          positive regulation of cell proliferation
          response to virus
          positive regulation of autophagy
          positive regulation of gene expression
          negative regulation of gene expression
          positive regulation of epithelial cell migration
          antigen processing and presentation
          neutrophil chemotaxis
          negative regulation of epithelial cell differentiation
          endoplasmic reticulum unfolded protein response
          negative regulation of myelination
          positive regulation of synaptic transmission, cholinergic
          negative regulation of interleukin-17 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-23 production
          positive regulation of tumor necrosis factor production
          positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
          positive regulation of peptidyl-serine phosphorylation of STAT protein
          positive regulation of smooth muscle cell apoptotic process
          positive regulation of T cell proliferation
          response to drug
          positive regulation of tyrosine phosphorylation of Stat1 protein
          defense response to bacterium
          defense response to protozoan
          negative regulation of growth of symbiont in host
          positive regulation of chemokine biosynthetic process
          positive regulation of interleukin-12 biosynthetic process
          positive regulation of MHC class II biosynthetic process
          positive regulation of interleukin-6 biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          positive regulation of neuron differentiation
          positive regulation of osteoclast differentiation
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of isotype switching to IgG isotypes
          negative regulation of smooth muscle cell proliferation
          positive regulation of interleukin-1 beta secretion
          regulation of insulin secretion
          T cell receptor signaling pathway
          sensory perception of mechanical stimulus
          positive regulation of membrane protein ectodomain proteolysis
          defense response to virus
          positive regulation of killing of cells of other organism
          interferon-gamma-mediated signaling pathway
          regulation of interferon-gamma-mediated signaling pathway
          positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
          positive regulation of fructose 1,6-bisphosphate metabolic process
          positive regulation of vitamin D biosynthetic process
          positive regulation of calcidiol 1-monooxygenase activity
          cellular response to lipopolysaccharide
          cellular response to interleukin-18
          positive regulation of establishment of protein localization to plasma membrane
          extrinsic apoptotic signaling pathway
          regulation of neuronal action potential
          positive regulation of exosomal secretion
          positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
          regulation of hepatocyte proliferation
          cytokine activity
          interferon-gamma receptor binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 TC12001696.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 TC12001696.hg.1 HTA TC
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 TC1200011177.hg.1 Clariom D TC

          Back To Top
           

          Citations (31)

          The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.
          Authors
          Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
          Journal
          Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 EDT 2009)
          Volume (Year)
          52 (2009)
          Product Usage
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          Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin.
          Authors
          Johansen C, Usher PA, Kjellerup RB, Lundsgaard D, Iversen L, Kragballe K
          Journal
          Br J Dermatol - Page No 319 (Sun Feb 01 00:00:00 EST 2009)
          Volume (Year)
          160 (2009)
          Product Usage
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          Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells.
          Authors
          Evans KN, Nguyen L, Chan J, Innes BA, Bulmer JN, Kilby MD, Hewison M
          Journal
          Biol Reprod - Page No 816 (Fri Dec 01 00:00:00 EST 2006)
          Volume (Year)
          75 (2006)
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          Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.
          Authors
          Hueso M, Navarro E, Moreso F, O'Valle F, Perez-Riba M, Del Moral RG, Grinyo JM, Seron D
          Journal
          Am J Pathol - Page No 1696 (Thu Apr 01 00:00:00 EDT 2010)
          Volume (Year)
          176 (2010)
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          Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome.
          Authors
          Chetaille B, Bertucci F, Finetti P, Esterni B, Stamatoullas A, Picquenot JM, Copin MC, Morschhauser F, Casasnovas O, Petrella T, Molina T, Vekhoff A, Feugier P, Bouabdallah R, Birnbaum D, Olive D, Xerri L
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          Blood - Page No 2765 (Thu Mar 19 00:00:00 EDT 2009)
          Volume (Year)
          113 (2009)
          Product Usage
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          Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells.
          Authors
          Ito T, Kanzler H, Duramad O, Cao W, Liu YJ
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          Blood - Page No 2423 (Wed Mar 15 00:00:00 EST 2006)
          Volume (Year)
          107 (2006)
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          Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
          Authors
          Tadokera R, Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Seldon R, Chegou NN, Maartens G, Rangaka MX, Rebe K, Walzl G, Wilkinson RJ
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          Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.
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          Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
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          Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 EST 2005)
          Volume (Year)
          152 (2005)
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          IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma.
          Authors
          Frederiksen KS, Lundsgaard D, Freeman JA, Hughes SD, Holm TL, Skrumsager BK, Petri A, Hansen LT, McArthur GA, Davis ID, Skak K
          Journal
          Cancer Immunol Immunother - Page No 1439 (Wed Oct 01 00:00:00 EDT 2008)
          Volume (Year)
          57 (2008)
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          Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.
          Authors
          Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, Grunewald J
          Journal
          Respir Res - Page No 42 (Thu Jan 01 00:00:00 EST 2009)
          Volume (Year)
          10 (2009)
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          Evasion of the mucosal innate immune system by herpes simplex virus type 2.
          Authors
          Peng T, Zhu J, Klock A, Phasouk K, Huang ML, Koelle DM, Wald A, Corey L
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          J Virol - Page No 12559 (Tue Dec 01 00:00:00 EST 2009)
          Volume (Year)
          83 (2009)
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          Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.
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          Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
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          Clin Cancer Res - Page No (Mon Oct 25 00:00:00 EDT 2010)
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          Comparing microarray versus RT-PCR assessment of renal allograft biopsies: similar performance despite different dynamic ranges.
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          Allanach K, Mengel M, Einecke G, Sis B, Hidalgo LG, Mueller T, Halloran PF
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          Am J Transplant - Page No 1006 (Thu May 01 00:00:00 EDT 2008)
          Volume (Year)
          8 (2008)
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          New means to monitor the effect of glucocorticoid therapy in children.
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          Rintamaki H, Salo HM, Vaarala O, Kolho KL
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          World J Gastroenterol - Page No 1104 (Sun Mar 07 00:00:00 EST 2010)
          Volume (Year)
          16 (2010)
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          T helper 2 biased de novo immune response to Keyhole Limpet Hemocyanin in humans.
          Authors
          Spazierer D, Skvara H, Dawid M, Fallahi N, Gruber K, Rose K, Lloyd P, Heuerding S, Stingl G, Jung T
          Journal
          Clin Exp Allergy - Page No 999 (Wed Jul 01 00:00:00 EDT 2009)
          Volume (Year)
          39 (2009)
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          Prospective monitoring of tumor necrosis factor alpha and interferon gamma to predict the onset of acute and chronic graft-versus-host disease after allogeneic stem cell transplantation.
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          Ritchie D, Seconi J, Wood C, Walton J, Watt V
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          Biol Blood Marrow Transplant - Page No 706 (Thu Sep 01 00:00:00 EDT 2005)
          Volume (Year)
          11 (2005)
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          Regulation of the tonsil cytokine milieu favors HIV susceptibility.
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          Moutsopoulos NM, Vazquez N, Greenwell-Wild T, Ecevit I, Horn J, Orenstein J, Wahl SM
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          J Leukoc Biol - Page No 1145 (Wed Nov 01 00:00:00 EST 2006)
          Volume (Year)
          80 (2006)
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          Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation.
          Authors
          Vlad G, Ho EK, Vasilescu ER, Fan J, Liu Z, Cai JW, Jin Z, Burke E, Deng M, Cadeiras M, Cortesini R, Itescu S, Marboe C, Mancini D, Suciu-Foca N
          Journal
          Transpl Immunol - Page No 13 (Sun Jul 01 00:00:00 EDT 2007)
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          Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.
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          Sandig H, McDonald J, Gilmour J, Arno M, Lee TH, Cousins DJ
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          Proc Natl Acad Sci U S A - Page No 12440 (Tue Jul 24 00:00:00 EDT 2007)
          Volume (Year)
          104 (2007)
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          Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions.
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          Simon D, Lindberg RL, Kozlowski E, Braathen LR, Simon HU
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          Exp Dermatol - Page No 441 (Thu Jun 01 00:00:00 EDT 2006)
          Volume (Year)
          15 (2006)
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          Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
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          Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R
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          J Immunol - Page No 7432 (Fri Jun 01 00:00:00 EDT 2007)
          Volume (Year)
          178 (2007)
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          Postmenopausal expression changes of immune system-related genes in human bone tissue.
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          Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P
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          J Clin Immunol - Page No 761 (Sun Nov 01 00:00:00 EDT 2009)
          Volume (Year)
          29 (2009)
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          Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.
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          Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
          Journal
          J Immunol - Page No 1724 (Sat Aug 01 00:00:00 EDT 2009)
          Volume (Year)
          183 (2009)
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          Characterization of the innate immune signalling pathways in hepatocyte cell lines.
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          Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P
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          J Viral Hepat - Page No 888 (Mon Dec 01 00:00:00 EST 2008)
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          Interferon-gamma expression is an independent prognostic factor in ovarian cancer.
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          Marth C, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Doppler W, Daxenbichler G
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          Am J Obstet Gynecol - Page No 1598 (Mon Nov 01 00:00:00 EST 2004)
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          191 (2004)
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          Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists.
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          Kamgang RK, Ramos I, Rodrigues Duarte L, Ghielmetti M, Freudenberg M, Dahinden C, Padovan E
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          Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.
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          Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenes C, Lafontan M, Galitzky J, Bouloumie A
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          The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
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          Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Gastl G, Gunsilius E, Marth C
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          Clin Cancer Res - Page No 8326 (Thu Dec 01 00:00:00 EST 2005)
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          Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
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          Clin Exp Immunol - Page No 479 (Mon Jun 01 00:00:00 EDT 2009)
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          Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
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          Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
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          Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes.
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          Cruz AR, Moore MW, La Vake CJ, Eggers CH, Salazar JC, Radolf JD
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