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          • › Search Tool
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          • › Hs00178463_m1
          See other ROCK1 GE Assays ›
          Gene Symbol:
          ROCK1
          Gene Name:
          Rho associated coiled-coil containing protein kinase 1
          Gene Aliases:
          P160ROCK, ROCK-I
          Chromosome Location:
          Chr.18: 20949740 - 21111851 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00178463_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: ROCK1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_005406.2 NP_005397.1 13 - 14 2353 121
          GenBank mRNA AB208965.1 - 5 - 6 446 121
          AK057038.1 - 13 - 14 2354 121
          AK307388.1 - 13 - 14 2168 121
          BC113114.1 - 13 - 14 1428 7961989 121
          U43195.1 - 13 - 14 1412 121

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC1800008219.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC18000397.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length greater than or equal to 101 Protein Kinase Mammalian Gene Collection Homo sapiens Human TGFB Panel Human NGF Pathway HUMAN PKA SIGNALING HUMAN BREAST CANCER REGULATION BY STATHMIN1 HUMAN GPCR PATHWAY HUMAN GUIDANCE CUES AND GROWTH CONE MOTILITY HUMAN THROMBIN SIGNALING HUMAN RHO FAMILY GTPASES HUMAN RHOA PATHWAY 1700 Inventoried Human_NGF_Pathway Human_TGFB Human_Guidance_Cues_and_Growth_Cone_Motility Human_GPCR_Pathway Human_PKA_Signaling Human_Thrombin_Signaling Human_Rho_Family_GTPases Human_RhoA_Pathway Human_Breast_Cancer_Regulation_by_Stathmin1 Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene ROCK1

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          apical constriction
          protein phosphorylation
          cellular component disassembly involved in execution phase of apoptosis
          smooth muscle contraction
          leukocyte cell-cell adhesion
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          Rho protein signal transduction
          negative regulation of angiogenesis
          membrane to membrane docking
          actin cytoskeleton organization
          regulation of cell adhesion
          cortical actin cytoskeleton organization
          bleb assembly
          negative regulation of protein binding
          regulation of actin cytoskeleton organization
          negative regulation of myosin-light-chain-phosphatase activity
          negative regulation of neuron apoptotic process
          regulation of keratinocyte differentiation
          vascular endothelial growth factor receptor signaling pathway
          ephrin receptor signaling pathway
          leukocyte migration
          leukocyte tethering or rolling
          myoblast migration
          regulation of stress fiber assembly
          regulation of focal adhesion assembly
          positive regulation of focal adhesion assembly
          establishment of protein localization to plasma membrane
          regulation of establishment of endothelial barrier
          negative regulation of bicellular tight junction assembly
          regulation of establishment of cell polarity
          regulation of cell motility
          protein kinase activity
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          GTP-Rho binding
          metal ion binding

          MicroArray Probes:

          Affymetrix ABI

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR18004082.hg.1 ENST00000399799.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR18004082.hg.1 NM_005406.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR18004082.hg.1 TC18000397.hg.1 HTA TC
          Affymetrix Human Clariom D Assay PSR1800156144.hg.1 ENST00000399799.2 Ensembl
          Affymetrix Human Clariom D Assay PSR1800156144.hg.1 NM_005406.2 Refseq
          Affymetrix Human Clariom D Assay PSR1800156144.hg.1 TC1800008219.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1800156144.hg.1 ENST00000399799.2 Ensembl
          Affymetrix Human Clariom D Assay PSR1800156144.hg.1 NM_005406.2 Refseq
          Array Name Probe IDs Targets Target Type
          ABI Human Genome Survey Microarray Version 2.0 229310 - -
          ABI Human Genome Survey Microarray Version 2.0 670499 - -

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