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          • Home
          • › Search Tool
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          • › Mm00439546_s1
          See other IFNB1 GE Assays ›
          Gene Symbol:
          Ifnb1
          Gene Name:
          interferon beta 1, fibroblast
          Gene Aliases:
          IFN-beta, IFNB, Ifb
          Chromosome Location:
          Chr.4: 88522025 - 88522794 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00439546_s1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (11)

          Genomic Map

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          Assay Details

          Gene Symbol: Ifnb1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_010510.1 NP_034640.1 1 51 61
          GenBank mRNA BC119395.1 - 1 51 8734144 61
          BC119397.1 - 1 51 8734146 61
          K00020.1 - 1 51 61

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0400003001.mm.1

          Additional Information:

          This assay is in the 5'UTR region of the BC119395.1,BC119397.1,K00020.1,NM_010510.1 transcripts.

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Apoptosis Mammalian Gene Collection Detect Genomic DNA Mus musculus Inventoried Both primers and probe map within a single exon

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Ifnb1

          Panther Classification:

          Molecular Function -

          interferon superfamily

          Gene Ontology Categories:

          Function(s) Process(es)

          adaptive immune response
          T cell activation involved in immune response
          B cell activation involved in immune response
          natural killer cell activation involved in immune response
          defense response
          humoral immune response
          cytokine-mediated signaling pathway
          B cell differentiation
          positive regulation of peptidyl-serine phosphorylation of STAT protein
          cellular response to interferon-beta
          B cell proliferation
          defense response to bacterium
          response to exogenous dsRNA
          negative regulation of viral genome replication
          negative regulation of T cell differentiation
          positive regulation of transcription from RNA polymerase II promoter
          defense response to virus
          type I interferon signaling pathway
          cellular response to dexamethasone stimulus
          negative regulation of T-helper 2 cell cytokine production
          positive regulation of apoptotic signaling pathway
          cytokine activity
          cytokine receptor binding
          type I interferon receptor binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0400024292.mm.1 TC0400003001.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0400024292.mm.1 NM_010510.1.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0400024292.mm.1 NM_010510.1 Refseq

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          Citations (11)

          Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells.
          Authors
          Uhl M, Kepp O, Jusforgues-Saklani H, Vicencio JM, Kroemer G, Albert ML
          Journal
          Cell Death Differ - Page No 991 (Wed Jul 01 00:00:00 EDT 2009)
          Volume (Year)
          16 (2009)
          Product Usage
          -
          Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunity.
          Authors
          Shen H, Panchanathan R, Rajavelu P, Duan X, Gould KA, Choubey D
          Journal
          J Mol Cell Biol - Page No 284 (Fri Oct 01 00:00:00 EDT 2010)
          Volume (Year)
          2 (2010)
          Product Usage
          -
          The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling.
          Authors
          Goodman AG, Zeng H, Proll SC, Peng X, Cilloniz C, Carter VS, Korth MJ, Tumpey TM, Katze MG
          Journal
          J Virol - Page No 2027 (Mon Feb 01 00:00:00 EST 2010)
          Volume (Year)
          84 (2010)
          Product Usage
          -
          Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.
          Authors
          Fairhurst AM, Xie C, Fu Y, Wang A, Boudreaux C, Zhou XJ, Cibotti R, Coyle A, Connolly JE, Wakeland EK, Mohan C
          Journal
          J Immunol - Page No 6831 (Sun Nov 15 00:00:00 EST 2009)
          Volume (Year)
          183 (2009)
          Product Usage
          -
          Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier.
          Authors
          Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Grone HJ, Anders HJ
          Journal
          Immunology - Page No e206 (Tue Sep 01 00:00:00 EDT 2009)
          Volume (Year)
          128 (2009)
          Product Usage
          -
          Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes.
          Authors
          Shigemoto T, Kageyama M, Hirai R, Zheng J, Yoneyama M, Fujita T
          Journal
          J Biol Chem - Page No 13348 (Fri May 15 00:00:00 EDT 2009)
          Volume (Year)
          284 (2009)
          Product Usage
          -
          Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro.
          Authors
          Balga R, Wetterwald A, Portenier J, Dolder S, Mueller C, Hofstetter W
          Journal
          Bone - Page No 325 (Tue Aug 01 00:00:00 EDT 2006)
          Volume (Year)
          39 (2006)
          Product Usage
          -
          Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.
          Authors
          Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, Garcia-Sastre A, Katze MG, Gale M Jr
          Journal
          J Virol - Page No 335 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          82 (2008)
          Product Usage
          -
          Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.
          Authors
          Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ
          Journal
          J Exp Med - Page No 1879 (Mon Aug 04 00:00:00 EDT 2008)
          Volume (Year)
          205 (2008)
          Product Usage
          -
          Inflammatory responses to pneumovirus infection in IFN-alpha beta R gene-deleted mice.
          Authors
          Garvey TL, Dyer KD, Ellis JA, Bonville CA, Foster B, Prussin C, Easton AJ, Domachowske JB, Rosenberg HF
          Journal
          J Immunol - Page No 4735 (Sat Oct 01 00:00:00 EDT 2005)
          Volume (Year)
          175 (2005)
          Product Usage
          -
          Differential roles of estrogen receptors alpha and beta in control of B cell maturation and selection(1).
          Authors
          Hill L, Venkatesh J, Chinnasamy P, Grimaldi C, Diamond B
          Journal
          Mol Med - Page No (Mon Nov 22 00:00:00 EST 2010)
          Volume (Year)
           (2010)
          Product Usage
          -

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