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          • Home
          • › Search Tool
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          • › Mm00446191_m1
          See other IL6 GE Assays ›
          Gene Symbol:
          Il6
          Gene Name:
          interleukin 6
          Gene Aliases:
          Il-6
          Chromosome Location:
          Chr.5: 30013161 - 30019968 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00446191_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Il6
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_031168.1 NP_112445.1 3 - 4 347 124
          GenBank mRNA AK089780.1 - 3 - 4 366 124
          AK150440.1 - 3 - 4 366 124
          AK152189.1 - 2 - 3 353 124
          BC132458.1 - 3 - 4 340 40130735 124
          BC138766.1 - 3 - 4 340 8861788 124
          BC145409.1 - 3 - 4 340 124
          DQ788722.1 - 3 - 4 316 124
          J03783.1 - 3 - 4 364 124
          X06203.1 - 3 - 4 349 124
          X54542.1 - 3 - 4 347 124

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0500000283.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length greater than or equal to 101 Apoptosis Mammalian Gene Collection Mus musculus Mouse lipid regulated genes Inventoried Mouse_lipid_regulated_genes Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Il6

          Gene Ontology Categories:

          Function(s) Process(es)

          neutrophil apoptotic process
          myeloid cell homeostasis
          hepatic immune response
          positive regulation of acute inflammatory response
          negative regulation of protein kinase activity
          acute-phase response
          inflammatory response
          immune response
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          regulation of cell shape
          response to wounding
          regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          cell growth
          cytokine-mediated signaling pathway
          endocrine pancreas development
          neuron projection development
          positive regulation of chemokine production
          positive regulation of interleukin-6 production
          negative regulation of collagen biosynthetic process
          positive regulation of peptidyl-serine phosphorylation
          positive regulation of protein import into nucleus, translocation
          positive regulation of T cell proliferation
          T cell activation
          regulation of cell proliferation
          positive regulation of tyrosine phosphorylation of Stat3 protein
          glucose homeostasis
          defense response to protozoan
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of MAPK cascade
          negative regulation of chemokine biosynthetic process
          regulation of circadian sleep/wake cycle, non-REM sleep
          positive regulation of nitric oxide biosynthetic process
          cell redox homeostasis
          positive regulation of T-helper 2 cell differentiation
          positive regulation of neuron differentiation
          negative regulation of gluconeogenesis
          positive regulation of translation
          positive regulation of DNA replication
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JAK-STAT cascade
          muscle cell cellular homeostasis
          negative regulation of hormone secretion
          negative regulation of muscle organ development
          positive regulation of smooth muscle cell proliferation
          positive regulation of epithelial cell proliferation
          negative regulation of cytokine secretion
          positive regulation of peptidyl-tyrosine phosphorylation
          positive regulation of B cell activation
          positive regulation of immunoglobulin secretion
          positive regulation of sequence-specific DNA binding transcription factor activity
          response to glucocorticoid
          defense response to virus
          positive regulation of protein kinase B signaling
          positive regulation of transmission of nerve impulse
          branching involved in salivary gland morphogenesis
          epithelial cell proliferation involved in salivary gland morphogenesis
          glucagon secretion
          interleukin-6-mediated signaling pathway
          cellular response to hydrogen peroxide
          positive regulation of ERK1 and ERK2 cascade
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          T-helper 17 cell lineage commitment
          negative regulation of neuron death
          receptor binding
          cytokine activity
          interleukin-6 receptor binding
          protein binding
          growth factor activity

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0500002169.mm.1 TC0500000283.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0500002169.mm.1 NM_031168.2 Refseq

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