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          • Home
          • › Search Tool
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          • › Mm00446500_g1
          See other TIRAP GE Assays ›
          Gene Symbol:
          Tirap
          Gene Name:
          toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
          Gene Aliases:
          AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
          Chromosome Location:
          Chr.9: 35184391 - 35200291 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00446500_g1
          Size
          Availability Made To Order
          Catalog # 4351372
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Tirap
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001177845.1 NP_001171316.1 3 - 4 344 67
          NM_001177846.1 NP_001171317.1 3 - 4 326 67
          NM_001177847.1 NP_001171318.1 3 - 4 272 67
          NM_054096.2 NP_473437.2 3 - 4 336 67
          GenBank mRNA AF378130.1 - 3 - 4 245 67
          AF410784.1 - 2 - 3 168 67
          AK036431.1 - 3 - 4 265 67
          AK080135.1 - 3 - 4 345 67
          AK151117.1 - 3 - 4 274 67
          AK168494.1 - 3 - 4 264 67
          BY740695.1 - 3 - 4 332 67
          BY743490.1 - 3 - 4 272 67

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0900002008.mm.1

          Additional Information:

          This assay is in the 5'UTR region of the AF378130.1, AF410784.1, AK036431.1, AK080135.1, AK151117.1, AK168494.1, NM_001177845.1, NM_001177846.1, NM_001177847.1, NM_054096.2 transcripts.

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Detect Genomic DNA Mus musculus Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Tirap

          Gene Ontology Categories:

          Function(s) Process(es)

          immune system process
          inflammatory response
          signal transduction
          cell surface receptor signaling pathway
          I-kappaB kinase/NF-kappaB signaling
          response to bacterium
          myeloid cell differentiation
          positive regulation of B cell proliferation
          response to lipopolysaccharide
          regulation of interferon-beta production
          regulation of interleukin-15 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-15 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of toll-like receptor 2 signaling pathway
          positive regulation of toll-like receptor 3 signaling pathway
          positive regulation of toll-like receptor 4 signaling pathway
          toll-like receptor 5 signaling pathway
          TIRAP-dependent toll-like receptor 4 signaling pathway
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          innate immune response
          regulation of innate immune response
          positive regulation of innate immune response
          positive regulation of JNK cascade
          defense response to Gram-positive bacterium
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of ERK1 and ERK2 cascade
          interleukin-1-mediated signaling pathway
          3'-UTR-mediated mRNA stabilization
          cellular response to bacterial lipopeptide
          cellular response to lipoteichoic acid
          positive regulation of neutrophil chemotaxis
          positive regulation of protein homodimerization activity
          positive regulation of chemokine (C-X-C motif) ligand 1 production
          positive regulation of chemokine (C-X-C motif) ligand 2 production
          protein kinase C binding
          protein binding
          phosphatidylinositol-4,5-bisphosphate binding
          Toll-like receptor 4 binding
          Toll-like receptor 2 binding
          protein homodimerization activity
          protein heterodimerization activity

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 TC0900002008.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177845.1.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177845.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177846.1.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177846.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177847.1.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_001177847.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_054096.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0900016676.mm.1 NM_054096.2 Refseq

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